Objective: To explore the significance of serum cytokeratin 18-M30 fragment (CK18-M30) and cytokeratin 18-M65 fragment (CK18-M65) levels in screening of fatty liver in physical examination population, and analysis of risk factors for fatty liver. Method: A total of 147 physical examiners from July 2020 to June 2022 in Taicang First People's Hospital were selected as the subjects of this study. The detection of fatty liver in physical examiners was recorded, and they were divided into fatty liver group (n=38) and non fatty liver group (n=109) according to whether they had fatty liver. The expression levels of CK18-M30 and CK18-M65 in serum of the two groups were compared, the factors influencing fatty liver were analyzed by univariate and multivariate logistic regression, and the application value of their expression levels in the diagnosis of fatty liver was analyzed with receiver operating characteristic (ROC). Result: Among 147 examiners, a total of 38 patients with fatty liver were detected, with a detection rate of 25.85% (38/147). The expression levels of CK18-M30 and CK18-M65 in the serum of the fatty liver group were higher than those of the non fatty liver group, the differences were statistically significant (P<0.05). The results of univariate analysis showed that there were no significant differences in gender, age, and the levels of tumor necrosis factor-α (TNF-α), C-reactive protein (CRP) and aspartate aminotransferase (AST) between the two groups (P>0.05). The body mass index (BMI), waist circumference, the proportion of diabetes, hypertension, hyperlipidemia and alanine aminotransferase (ALT) levels in the fatty liver group were significantly higher than those in the non fatty liver group, the differences were statistically significant (P<0.05). Multivariate logistic regression analysis showed that high BMI (OR=1.874), high waist circumference (OR=2.114), combined diabetes (OR=2.257), high CK18-M30 (OR=2.577), and high CK18-M65 (OR=1.974) were independent risk factors for fatty liver (P<0.05). The results of ROC analysis showed that the area under the curve (AUC) of CK18-M30 and CK18-M65 in the diagnosis of fatty liver was 0.885 (95%CI: 0.822, 0.948), significantly higher than 0.735 (95%CI: 0.636, 0.834) of CK18-M30 alone and 0.778 (95%CI: 0.704, 0.853) of CK18-M65 alone. Conclusion: High BMI, High waist circumference, combined diabetes, high CK18-M30 and high CK18-M65 are independent risk factors for fatty liver. The levels of CK18-M30 and CK18-M65 show abnormally high expression in the serum of patients with fatty liver, which has good clinical diagnostic effect in fatty liver, and can be used as effective indicators for screening fatty liver in the physical examination population.

Objective: To assess the therapeutic response of tongue acupuncture in patients with post-stroke dysphagia (PSD). Method: Medical records of PSD patients consecutively admitted to Yangjiang Hospital of Traditional Chinese Medicine between October 2021 and December 2022 were retrospectively analyzed. Eighty patients meeting the inclusion criteria were enrolled. Participants were stratified into a control group (n=40) and a tongue acupuncture group (n=40) based on the specific therapeutic regimen received. The control group was given rehabilitation therapy, while the treatment group was combined with tongue acupuncture. The differences in Water Swallowing Test (WST) grades and Standardized Swallowing Assessment (SSA) scores were compared. The therapeutic outcomes and adverse events were documented following the intervention period. Result: Baseline equivalence in WST grades and SSA scores was observed, demonstrated no significant intergroup differences (P>0.05). Post-therapy, the tongue acupuncture cohort demonstrated greater WST improvement, lower SSA scores, and higher clinical efficacy rates versus controls, differences were statistically significant (P<0.05). No adverse events occurred in either group. Conclusion: Tongue acupuncture combined with rehabilitation achieves superior dysphagia mitigation in PSD compared to rehabilitation alone, with sustained short-term effects observed at 3-month follow-up and an optimal safety trajectory.

Migraine is a common chronic neurovascular disease in clinical practice, with repeated attacks, stubborn and difficult to heal as the main characteristics, to the patient's physical and psychological caused significant distress, greatly affecting the quality of life of patients. In recent years, the in-depth study of intestinal microecology theory has found that intestinal flora can participate in the occurrence and development of migraine through various ways. Based on the theory of "microbial-gut-brain axis", this paper discusses the four aspects of meridians, Qi and blood, emotions, phlegm turbidity, so as to provide the basis for the treatment of migraine by spleen and stomach in traditional Chinese medicine.

Objective: To explore the effectiveness of mind mapping health education in patients with colorectal cancer with temporary colostomy. Method: 130 patients with colorectal cancer with temporary enterostomy admitted to Jianyang First Hospital in Nanping City from June 2020 to June 2024 were selected the subjects, and were randomly into the study and the control group, 65 cases in group. The control received conventional rehabilitation nursing care, and the study group used thinking guide health education, and both groups received nursing care for a period of 12 weeks . Before and after the intervention, self-care ability, survival quality, peristoma skin status, awareness and complications were compared between the two groups. Result: After 12 weeks of intervention, erosion, discoloration, and tissue proliferation scores lower in study group compared the control, and difference was statisically sigifiant (P<0.05). The quality of cancer survival scores in the 3 domains of symptomatic domain, functional domain and general health status were elevated in study group compared the control group, the difference was statistcally signifcant (P<0.05). The scores the dimensions of self-care ability the study increased mpared with the trol group, and the diffence was statiscally signcant (P<0.05). Knowledge scores the 3 dimensions of complication recognition, stoma replacement, and precautions were elevated in the study compared with control group, difference was stastically signcant (P<0.05). The complicon rate of the study group was lwer than that of the control, and the difference was stastically signifnt (P<0.05). Conclusion: Mind mapping health education can better improve the quality of cancer survival and peristoma skin status of colorectal cancer patients with temporary colostomy, improve self-care ability and knowledge.

Objective: To investigate the clinical effectiveness of analgesic and sedative comfort nursing combined with seamless care for patients with severe pneumonia and diabetes undergoing mechanical ventilation. Method: A total of 80 patients with severe pneumonia and diabetes undergoing mechanical ventilation admitted to the First Affiliated Hospital of Xiamen University from January to December 2023, were enrolled and randomly assigned using random number table into observation group (n=40) and control group (n=40). The control group received routine care, while the observation group received analgesic and sedative comfort nursing combined with seamless care. Psychological status [Self-rated Anxiety Scale (SAS), Self-rated Depression Scale (SDS) score], treatment compliance, blood glucose levels (fasting and postprandial), duration of mechanical ventilation and hospitalization, as well as the incidence of adverse events were compared between the two groups. Result: After intervention, the observation group showed significantly lower SAS and SDS scores compared to the control group; better treatment compliance and blood glucose control, shorter duration of mechanical ventilation and hospitalization, and a lower incidence of adverse events, the differences were all statistically significant (P<0.05). Conclusion: Analgesic and sedative comfort nursing combined with seamless care can effectively improve the psychological status and treatment compliance of patients with severe pneumonia and diabetes undergoing mechanical ventilation, stabilize blood glucose levels, reduce treatment duration, and lower the risk of adverse events, significantly enhancing overall clinical outcomes.

Objective: To explore the influence of different postures on patients after laryngeal mask removal in laparoscopic cholecystectomy. Method: According to the random number table method, 80 cases of laparoscopic cholecystectomy in the First Affiliated Hospital of Bengbu Medical University from March 2022 to July 2024 were divided into recumbent group (40 cases with pillows removed) and semi-recumbent group (40 cases with 30° semi-recumbent). The indexes of hemodynamics, pulmonary ventilation and respiratory mechanics of the two groups were compared. Result: There was no significant difference in heart rate (HR) and mean arterial pressure (MAP) at the end of operation, 10 min after laryngeal mask removal, 1 h after laryngeal mask removal and 2 h after laryngeal mask removal between the two groups (P>0.05). Forced vital capacity (FVC), forced expiratory volume in the first second (FEV 1) and FEV 1/FVC in the semi-recumbent group were all higher than those in the recumbent group, and the difference was statistically significant(P<0.05). The maximal expiratory pressure (MEP) and maximal inspiratory pressure (MIP) in the semi-recumbent group were higher than those in the recumbent group at 1 h and 2 h after the laryngeal mask removal, with statistical significance (P<0.05). Conclusion: In laparoscopic cholecystectomy, lying flat without a pillow and 30° semi-lying position will not affect the hemodynamics of patients after laryngeal mask removal, but 30° semi-lying position is more beneficial to the pulmonary ventilation and respiratory mechanics effect of patients.

Objective: To evaluate the efficacy of a precision intercostal nerve block for postoperative analgesia in single-port television-assisted thoracoscopic surgery. Method: 100 patients who underwent single-hole TV-assisted thoracoscopic surgery in the Affiliated Hospital of Qinghai University from January 2022 to January 2023 were selected as the study subjects, and randomly divided into the precise intercostal nerve block (PINB) group and the local infiltration anesthesia (LIA) group, with 50 cases in each group. Pain levels were assessed in the patients' quiet state and deep breathing state in the post-anesthesia recovery room (PACU) (T1), 1 h after leaving the PACU (T2), 4 h (T3), 12 h (T4), and 24 h (T5). The quality of patients' postoperative recovery was assessed at the T5 time point using the 40-item Quality of Recovery Rating Scale (QoR-40). The number of patient controlled intravenous analgesia (PCIA) pump presses and the number of remedial analgesia were recorded for each postoperative period. The time of the first remedial analgesia, patient agitation during awakening, delayed awakening, chills, and the occurrence of adverse reactions such as postoperative nausea and vomiting (PONV), dizziness, skin itching, and hypoxemia during the 24 h postoperative period were recorded. Result: The visual analog scale (VAS) scores at the T2 time point during deep breathing were lower in the PINB group than in the LIA group, and the difference was statistically significant (P<0.05). The VAS at rest and at the T3 time point during deep breathing was lower in the PINB group than in the LIA group, and the difference was statistically significant (P<0.05). The scores of comfort category and pain category in QoR-40 in PINB group were higher than that in LIA group at 24 h after operation, and the difference was statistically significant (P<0.05). The number of PCIA presses and the number of remedial analgesia in PINB group in the time period of T1~T3 was less than that in LIA group, and the difference was statistically significant (P<0.05). The time of the first remedial analgesia in PINB group was shorter than that in LIA group, and the difference was statistically significant (P<0.05). Conclusion: Precision intercostal nerve block provides excellent postoperative analgesia with a high degree of safety in patients undergoing single-port television-assisted thoracoscopic surgery.

Objective: To analyze the influence of hospital to family seamless model nursing on the stigma and negative psychology of patients undergoing enterostomy. Method: A total of 80 patients undergoing enterostomy admitted to the Department of General Surgery of the First Affiliated Hospital of Xiamen University from January 2021 to June 2022 were selected as the study objects. They were divided into control group and observation group according to random number table method, with 40 cases in each group. The control group was given routine nursing, and the observation group was given hospital to family seamless model nursing on the basis of control group. Stigma, negative psychology before and after nursing and gastrointestinal function recovery time were compared between the two groups. Result: After nursing, the scores of social exclusion, intrinsic shame and social isolation in the observation group were lower than those in the control group, and the differences were statistically significant (P<0.05). After nursing, depression score and anxiety score in the observation group were lower than those in the control group, and the differences were statistically significant (P<0.05). The first feeding time, first ostomy defecation time and first ostomy exhaust time in the observation group were significantly earlier than those in the control group, and the differences were statistically significant (P<0.05). Conclusion: The hospital to family seamless model nursing can effectively reduce the sense of shame and negative psychological emotions of patients, and is more conducive to promoting the recovery of gastrointestinal function of patients.

Objective: Observation of the surgical effect of ultrasound-guided percutaneous microwave ablation in the clinical treatment of benign thyroid nodules. Method: 284 patients with benign thyroid nodules from Shenzhen Hengsheng Hospital from July 2021 to July 2024 were selected as the study subjects. The grouping method was envelope randomization. The control group (142 cases) underwent conventional endoscopic unilateral thyroidectomy, while the study group (142 cases) underwent ultrasound-guided percutaneous microwave ablation. The clinical efficacy of the two groups was compared. Result: The appearance satisfaction, postoperative free triiodothyronine (FT3) levels, free tetraiodothyronine (FT4) levels and total thyroxine (TT4) levels of the study group were all higher than those of the control group, with significant difference (P<0.05). The postoperative thyroid stimulating hormone (TSH) levels, adrenocorticotropic hormone (ACTH) levels, aldosterone (ALD) levels, cortisol (Cor) levels, total white blood cell count (WBC) levels, tumor necrosis factor-α (TNF-α) levels, C-reactive protein (CRP) levels, and pain index (VAS) scores of the study group were all lower than those of the control group, with significant difference (P<0.05). The improvement of perioperative indicators in the research group was better than that in the control group, with significant difference (P<0.05). Postoperative complications are comparable between the two groups with no signigicant difference (P>0.05). Conclusion: Ultrasound guided percutaneous microwave ablation for the treatment of benign thyroid nodules can promote postoperative appearance satisfaction, reduce thyroid function damage, alleviate postoperative traumatic stress and inflammatory reactions, improve rehabilitation efficiency, and improve prognosis.

Objective: To analyze the effects of psychological nursing interventions on symptom self-assessment scores and quality of life levels in patients with first-time stroke. Method: A total of 82 patients with first-time stroke admitted to Gaochun People's Hospital in Nanjing from January to November 2024 were selected as the study subjects. They were divided into an observation group and a control group using the envelope method, with 41 cases in each group. The control group received routine nursing intervention, while the observation group received psychological intervention in addition to the routine nursing intervention. The psychological status and quality of life of the two groups were compared. Result: After intervention, anxiety, depression, fear, hostility, paranoia, somatization, obsessive-compulsive symptoms, interpersonal sensitivity, and psychoticism scores decreased in both groups, and the observation group had lower scores, with statistically significant differences (P<0.05). After intervention, both groups showed improvements in energy, mood, personality, thinking, family role, self-care ability, activity ability, and upper limb function scores, and the observation group showed higher scores, with statistically significant differences (P<0.05). Conclusion: Psychological care interventions for patients experiencing their first stroke can effectively improve their psychological condition and quality of life. However, patients often experience severe depression, which requires further targeted measures.

Dexamethasone is a synthetic long-acting glucocorticoid, a fluorinated derivative of prednisolone, with anti-inflammatory, antitoxic, anti-immune and antishock effects, excitation of the central nervous system, affecting the hematopoietic system, promoting the secretion of gastric acid, inhibiting the pineal gland's secretion of melatonin, and decreasing iodine ion uptake by the thyroid gland, which has been widely used in clinical practice. For unexplained fever and osteoarthritic pain, it has the effect of temporarily reducing fever and alleviating pain, which is favored by clinicians, especially in the primary health care institutions is a large number of applications, and even reached the point of abuse. The article found that dexamethasone would have adverse reactions such as ergotism, hypokalemic paralysis, anaphylactic shock, mental abnormality, perineal itching, urinary incontinence, acanthosis nigricans, epilepsy, gastric perforation, and femoral head necrosis in clinical application, which would cause unnecessary pain to patients. These adverse reactions occurring in the clinical application of dexamethasone in recent years are now analyzed and summarized to provide reference for future clinical application.

Objective: To compare the differences between percutaneous microballoon compression and radiofrequency thermocoagulation in the treatment of primary trigeminal neuralgia. Method: A retrospective review of clinical data from 86 patients with primary trigeminal neuralgia admitted to Yancheng NO.1 People's Hospital between August 2019 and August 2023 was conducted, and the patients were divided into two groups based on treatment modality: the balloon group and the radiofrequency group, with 43 patients in each group. The balloon group received percutaneous microballoon compression therapy, while the radiofrequency group received radiofrequency thermal coagulation therapy. The clinical efficacy, pain levels, recurrence rates, and incidence of complications were compared between the two groups. Result: After 3 months postoperatively, there was no statistically significant difference in the overall clinical efficacy rate between the two groups (P>0.05). Compared with 1 month postoperatively, the visual analog scale scores were higher in both groups at 3 months postoperatively, with a statistically significant difference (P<0.05). The recurrence rate was higher in the radiofrequency group than in the balloon group, but the difference was not statistically significant (P>0.05). The incidence of facial numbness and masseter muscle weakness was lower in the radiofrequency group than in the balloon group, while the incidence of corneal discomfort was higher in the radiofrequency group than in the balloon group, and both differences were statistically significant (P<0.05). There was no statistically significant difference in the incidence of oral herpes between the two groups (P>0.05). Conclusion: Microballoon compression and radiofrequency thermocoagulation are similar in their effectiveness in treating patients with primary trigeminal neuralgia. Both procedures result in similar pain relief and recurrence rates one year after surgery. However, percutaneous microballoon compression has a lower incidence of complications such as facial numbness and masseter muscle weakness, but a higher incidence of corneal discomfort.

Objective: To observe the effect of Cameron's timely theoretical rehabilitation exercises combined with first-perspective multifaceted evangelism in patients undergoing hip arthroplasty for femoral neck fracture. Method: 94 patients with femoral neck fracture who underwent hip arthroplasty treatment in Putian First Hospital from July 2023 to June 2024 were selected as the study subjects, and were divided into experimental group and control group by coin-flip method, with 47 cases in each group. The control group followed the conventional rehabilitation mode of hip arthroplasty for femoral neck fracture to carry out nursing activities, and the experimental group added Cameron's timely theoretical rehabilitation exercise combined with the first perspective multivariate missionary intervention. The indicators of the two groups after the intervention were compared. Result: The TSK-11 score of the experimental group was lower than that of the control group, the rehabilitation exercise adherence score was higher than that of the control group, the rehabilitation effect indexes were better than that of the control group, and the complication rate was lower than that of the control group, and the difference was statistically significant (P<0.05). Conclusion: The use of Cameron's timely theory of rehabilitation exercise combined with the first perspective multivariate missionary intervention for hip arthroplasty patients with femoral neck fracture can reduce the patients' fear of exercise, improve the patients' adherence to rehabilitation exercise, optimize the patients' rehabilitation effect, and reduce the incidence of complications.

Objective: To compare the effectiveness of perioperative care based on situational leadership theory with traditional care in patients with osteoporotic vertebral compression fractures (OCVF) undergoing percutaneous vertebroplasty (PVP). Method: 200 OVCF patients who underwent PVP in Dongguan Donghua Hospital from September 2023 to September 2024 were selected and divided into the control group (100 cases) and the observation group (100 cases) randomly. Traditional nursing methods was used in the control group, and the observation group was given perioperative care using the situational leadership theory. The visual analog scale (VAS) score was used to assess the patients' pain relief. The patients' satisfaction evaluated, and the length of hospitalization, the time to get off the floor, the adherence to rehabilitation, and the occurrence of postoperative complications were observed in the two groups. Result: The postoperative pain relief rate of the observation group was higher than that of the control group, and statistically significant was seen in the difference (P<0.05). The hospitalization time, postoperative time out of bed, postoperative complication rate, nursing satisfaction, and rehabilitation compliance rate in observation group were better, and statistically significant was seen in the difference (P<0.05). Conclusion: Perioperative care based on the situational leadership theory can effectively improve the quality of care for patients undergoing PVP for OVCF and promote patient recovery.

Objective: To explore the application effect of prenatal perineal massage combined with psychological counseling in primiparas. Method: A total of 200 primiparas admitted to the Zhongshan People's Hospital from June 2023 to June 2024 were selected as the research subjects and divided into two groups by envelope method, with 100 cases in each group. Both groups received conventional care. The control group was combined with psychological counseling, while the observation group was combined with prenatal perineal massage on the basis of the control group. Both groups completed 3 d care. The psychological resilience, stress response, role transition scores and delivery outcomes of the two groups were compared. Result: The observation group had a higher score on the Connor-Davidson Resilience Scale (CD-RISC) after intervention than the control group, with a statistically significant difference (P<0.05). Both groups of primiparous women had varying degrees of stress response, but the degree of stress response in the observation group was milder than that in the control group. The stress response indicators in the observation group were lower than those in the control group. The role transition score and normal delivery rate in the observation group were higher than those in the control group after intervention, and the rate of instrumental delivery was slightly lower than that in the control group, with a statistically significant difference (P<0.05). Conclusion: Prenatal perineal massage combined with psychological counseling for primiparas can help improve their psychological resilience, reduce the stress response during delivery, increase the role transition score, reduce the incidence of instrument delivery, and increase the rate of normal delivery.

Objective: To investigate the effects of ultrasound-guided dual nerve block technology on analgesia, motor function preservation, and postoperative recovery in ankle surgery patients. Method: A total of 80 patients undergoing ankle surgery at Xinhui District Hospital of Traditional Chinese Medicine in Jiangmen City, Guangdong Province from April to November 2024 were selected as subjects. The study was divided into experimental and control groups using equalized sequential matching. Equalized sequential matching was applied, with 40 cases in the control group receiving combined spinal-epidural anesthesia and 40 cases in the experimental group receiving ultrasound-guided popliteal popliteal nerve block combined with obturator block. The effectiveness of the control anesthesia protocol during surgical treatment was evaluated. Result: Analysis of heart rate, systolic blood pressure, diastolic blood pressure, and oxygen saturation levels showed no significant differences across time periods. Systolic and diastolic blood pressure remained unchanged before anesthesia initiation and at the end of surgery. However, the experimental group exhibited higher blood pressure at the start of surgery and 30 minutes post-surgery compared to the control group, with statistically significant difference (P<0.05). No significant difference was observed at 1 h postoperative, but statistically significant differences (P<0.05) were found at 12 h and 24 h postoperative, indicating better analgesia outcomes. The experimental group also demonstrated superior nerve block efficacy compared to the control group (P<0.05). Conclusion: During ankle surgery, implementing ultrasound-guided popliteal popliteal nerve block combined with obturator block ensures reliable anesthesia blockade, maintains stable circulatory status, and delivers high-quality analgesia.

Objective: To analyze the effects of a new perineal massage technique combined with a responsibility-based one-to-one nursing model on labor progression and delivery outcomes in primiparous women. Method: A total of 200 primiparous women who delivered at the Zunyi Maternal and Child Health Hospital from April to November 2024 were selected as study subjects. They were divided into a control group (96 cases) and an observation group (104 cases) based on differences in nursing methods during delivery. The control group received one-to-one nursing care under the responsibility system, while the observation group received the new perineal massage technique in addition to one-to-one nursing care under the responsibility system. The two groups were compared in terms of labor progression and delivery outcomes. Result: There was no statistically significant difference in the specific duration of the first and third stages of labor between the two groups (P>0.05). The duration of the second stage of labor was significantly shorter in the observation group compared to the control group (P<0.05) . The incidence of perineal side incisions, tears, and the severity of perineal edema were lower in the observation group than in the control group, with statistically significant differences (P<0.05). There were no statistically significant differences between the two groups in terms of cesarean section rates and postpartum complications (P>0.05). Conclusion: The new perineal massage technique combined with a responsibility-based one-to-one nursing model can accelerate the second stage of labor in primiparous women, protect perineal integrity, and result in better delivery outcomes.

Lumbar disc herniation (LDH) is a common condition in clinical practice, particularly in orthopedics, often causing lower back and leg pain and affecting patients' quality of life. Traditional Chinese medicine acupuncture has been shown to be effective in treating LDH patients, offering advantages such as simplicity, convenience, affordability and reliability, and plays an irreplaceable role in treatment. The article reviews relevant literature on the mechanisms of action of acupuncture in the treatment of LDH over the past five years and summarizes the findings. The results indicate that acupuncture treatment for LDH is closely associated with multiple mechanisms of action, including reducing inflammation levels, improving bone metabolism, improving serum differential metabolite levels, regulating neurotransmitters, enhancing nerve conduction velocity, and improving blood rheology.

Objective: To explore the impact of refined care based on early warning scores for children on the nursing outcomes of pediatric patients with pneumonia admitted to the emergency department for observation. Method: A retrospective analysis was conducted on the medical records of 80 pediatric pneumonia patients admitted to Quanzhou Children's Hospital from May to October 2023. The patients were divided into two groups based on different nursing approaches, with 40 cases in each group. The control group received routine care based on early warning scores, while the observation group received specialized care based on early warning scores. The early warning assessment scores (PEWS), observation time, prognosis, and family satisfaction of the two groups of children were evaluated. Result: After nursing care, compared with the control group, the observation group had lower PEWS scores and shorter observation times, with statistically significant differences (P<0.05). The number of cases admitted to the PICU in the observation group was lower than that in the control group, while the number of outpatient follow-up cases was higher than that in the control group, with statistically significant differences (P<0.05). Family members in the observation group reported higher satisfaction with nursing care than those in the control group, with statistically significant differences (P<0.05). Conclusion: In the clinical treatment of pediatric pneumonia patients in the emergency department, the use of refined nursing care based on early warning scores can effectively shorten the observation time of patients, improve their prognosis, and increase the satisfaction of their families with the nursing care, thereby achieving significant nursing outcomes.

Objective: To investigate the prophylactic effect of the application of a plantar pump after femoral artery puncture intervention on lower extremity deep vein thrombosis (DVT) and its hemodynamic impact. Method: 196 patients who underwent femoral artery puncture intervention in the Second Affiliated Hospital of Shandong First Medical University from January 2020 to January 2025 were selected as the study subjects, and were randomly divided into observation group (n=98) and control group (n=98).The observation group used the plantar pump to promote blood circulation in the lower limbs after surgery, while the control group did not carry out this intervention. The clinical effect of the plantar pump was analyzed by comparing the incidence of postoperative DVT, hemodynamic changes, and patient comfort between the two groups. Result: In the experimental group, the incidence of lower limb venous thrombosis was significantly less than that in the control group after undergoing surgery, and this difference was statistically significant (P<0.05). In the control group, two cases developed lower limb oedema, and three cases felt discomfort after standing activities. Prior to clinical intervention, there was no significant difference between the two groups in terms of haemorheological parameters and coagulation function (P>0.05). On the first day after the intervention treatment, the partial thromboplastin time and prothrombin time of the two groups of patients did not show any significant changes, and there was no statistically significant difference between the two groups (P>0.05). In the observation group, platelet counts decreased, fibrinogen decreased, and plasma viscosity levels showed a downward trend, and this difference reached statistical significance when compared with the control samples (P<0.05). The concentration of D-dimer generally increased after the operation, but in the patients in the observation group, this increase was lower than that in the control group, and the difference between the two groups was statistically significant (P<0.05). The lower limb venous blood flow velocity in the observation group was significantly higher compared to the control group, and this difference was also statistically significant (P<0.05). Compared with the control sample, these indicators in the observation group showed significant improvement, and the satisfaction of the observation group increased, and the difference was statistically significant (P<0.05). Conclusion: The plantar pump as an adjunctive therapy is effective in preventing lower extremity DVT after femoral artery puncture interventions.

Objective: To explore the importance of actively implementing acupressure therapy to effectively alleviate the negative effects of pain after cesarean section. Method: 40 cases of cesarean section patients in the control group (routine nursing) and 40 cases in the observation group (acupuncture therapy) were all from Sinan County Traditional Chinese Medicine Hospital for Nationalities, and the selection period was from October 2023 to October 2024. The differences of pain and duration, effective pressing times of analgesic pump, recovery of intestinal function and nursing effect between the two groups before and after treatment were analyzed and explored. Result: Compared with the improvement of Numeric Rating Scale (NRS), the observation group was lower than the control group, and the difference was statistically significant (P<0.05). To compare the effective pressing times of analgesic pump, there was no significant difference between the observation group and the control group (P>0.05). Compared with the control group, the first defecation, the recovery of bowel sounds and the postoperative anal exhaust time in the observation group were all lower, and the difference was statistically significant (P<0.05). After nursing, the total effective rate in the observation group was higher than that in the control group, and the difference was statistically significant (P<0.05). Conclusion: Actively implementing acupressure therapy during the postoperative nursing period of cesarean section can effectively reduce postoperative pain, accelerate intestinal function recovery, and improve overall nursing effectiveness.

Objective: To compare the therapeutic effects of laparoscopic resection and open abdominal surgery on patients with uterine fibroids (UF). Method: 68 patients with uterine fibroids admitted to the Gaochun People's Hospital in Nanjing from January 2022 to June 2024 were selected and divided into group B (n=34, treated with open abdominal surgery) and group A (n=34, treated with laparoscopic resection) according to different surgical methods. Compare two groups of surgical indicators, Visual Analog Scale (VAS) scores, Generic Quality of Life Inventory (GQOLI-74) scores, and incidence of complications. Result: The surgical indicators in group A were superior to those in group B, and the difference was statistically significant (P<0.05)； The postoperative pain level in group A was lower than that in group B, and the difference was statistically significant (P<0.05)； The postoperative quality of life in group A was higher than that in group B, and the difference was statistically significant (P<0.05)； The incidence of complications in group A was lower than that in group B, and the difference was statistically significant (P<0.05).Conclusion: Compared with open surgery abdominal, laparoscopic resection is more effective in treating patients with uterine fibroids, which can further reduce pain, improve quality of life, and prevent postoperative complications.

Objective: To investigate the effect of non-invasive positive pressure ventilation (NPPV) combined with active short-term respiratory muscle resistance training on systemic inflammatory response levels in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Method: 80 AECOPD patients were selected as the study subjects from the Enshi Central Hospital from March 2022 to March 2024. They were randomly divided into two groups. Both groups of patients received routine symptomatic treatment and NPPV treatment, and 40 patients were observed using active short-term respiratory muscle resistance training. Both groups of patients were observed for one week. Compare lung function [FEV1/FVC, peak expiratory flow (PEF), FEV1], respiratory function [maximum expiratory pressure (MEP), diaphragmatic activity, maximum inspiratory pressure (MIP)], inflammatory markers [interleukin-8 (IL-8), tumor necrosis factor alpha (TNF-α), C-reactive protein (CRP)], and quality of life [Health Survey Brief (SF-36)]. Result: There was no statistically significant difference in the levels of various lung function indicators between the two groups of patients before intervention (P>0.05). After treatment, both groups of patients showed improvement in lung function. The observation group had higher levels of FEV1, PEF and FEV1/FVC after intervention, and the differences were statistically significant compared with the control group (P<0.05). There was no significant difference in the levels of respiratory function indicators between the two groups of patients before intervention (P>0.05). After intervention, both groups of patients showed recovery in respiratory function. The observation group had higher levels of MIP, MEP, and diaphragm activity after intervention (P<0.05). There was no statistically significant difference in the levels of various inflammatory indicators between the two groups of patients before intervention (P>0.05). After treatment, the inflammation in both groups of patients improved. The observation group had lower levels of IL-8, TNF-α, and CRP after intervention, and the differences were statistically significant compared with the control group (P<0.05). There was no statistically significant difference in the quality of life level between the two groups of patients before intervention (P>0.05). After treatment, the quality of life of both groups of patients improved. The observation group had a higher SF-36 level after intervention, and the difference was statistically significant compared with the control group (P<0.05). Conclusion: The combination of NPPV treatment and active short-term respiratory muscle resistance training is effective in AECOPD patients, improving respiratory function, reducing inflammation levels, and restoring lung function.

Objective: To analyze the clinical results of the application of nasal endoscopic treatment in the restoration of traumatic nasal bone fractures. Method: 100 cases of traumatic nasal bone fracture patients admitted to the People's Hospital of Pu'an County, from January 2021 to December 2024 were selected for clinical practice research, and they were divided into two groups by using the single and double number method. 50 cases who were assigned to single number were included in the control group, and the treatment method was traditional nasal bone resurfacing surgery, 50 cases who were assigned to double number were included in the observation group, and the treatment method was nasal endoscopic resurfacing surgery. Nasal volume, nasal breathing resistance, total effective rate of treatment and postoperative complication rate were evaluated and compared between the two groups before and after treatment. Result: After treatment, the nasal volume of the observation group was higher than that of the control group, the nasal breathing resistance of the observation group was lower than that of the control group, the total effective rate of treatment of the observation group was higher than that of the control group, and the incidence of postoperative complications of the observation group was lower than that of the control group, and the difference was statistically significant (P<0.05). Conclusion: Nasal endoscopic treatment of traumatic nasal bone fracture repositioning is clinically effective and safe.

　　Constipation is a common clinical symptom, which often leads to anorectal diseases, colorectal cancer, acute myocardial infarction, cerebrovascular accidents and other diseases. It affects the daily life of patients and causes economic and social burden. The unique "holistic concept" and "syndrome differentiation and treatment" theoretical system of traditional Chinese medicine has advantages in the treatment of constipation. In clinical practice, chronic constipation is common in the form of asthenia constipation, mainly in the form of Qi deficiency and Yin deficiency, and mostly mixed with each other. Therefore, this paper briefly describes the methods of treating constipation with deficiency of both Qi and Yin in recent years, with a view to providing inspiration or improving the deficiency of the treatment of constipation with deficiency of both Qi and Yin.

Objective: To observe the effect of treatment of refractory diabetic macular edema (DME) using intravitreal dexamethasone extended-release injection versus ranibizumab. Method: 68 patients with refractory DME admitted to Sanmenxia Hospital of Yellow River from June 2022 to June 2024 were selected as the study subjects, and were divided into the experimental group (dexamethasone extended-release agent combined with intravitreal injection of ranibizumab, 36 cases) and the control group (intravitreal injection of ranibizumab, 32 cases) according to the different modes of treatment. Retinal thickness (CMT), intraocular pressure (IOP), best corrected visual acuity (BCVA), number of injections of anti-vascular endothelial growth factor (VEGF) medication, recurrence of edema, and complication rate were compared between the two groups. Result: At 6 months of treatment, the difference in IOP between the two groups was not statistically significant (P>0.05). Compared with the control group, the experimental group had lower BCVA (logMAR) and CMT, fewer recurrences of edema, longer duration of edema recurrence, fewer injections of anti-VEGF drugs and lower overall complication rate, and the differences were all statistically significant (P<0.05). Conclusion: For refractory DME, the application of intravitreal dexamethasone extended-release injections with ranibizumab for treatment improves the patient's visual acuity and condition, reduces recurrence of edema, reduces the frequency of anti-VEGF drug injections, and enhances safety.

Objective: To compare the differences in clinical pharmacodynamic characteristics between Ciprofol and Propofol. Method: From July to October 2021, 80 patients underwent internal fixation of distal upper limb fractures in the Affiliated Hospital of Panzhihua University were randomly divided into Ciprofol group and Propofol group, 40 cases in each group. After the completion of ultrasound-guided brachial plexus block, two groups were intravenously pumped with 2 mg/kg Propofol and 0.4 mg/kg Ciprofol for 1 min. The mean arterial pressure (MAP), heart rate (HR), blood oxygen saturation (SpO₂) and bispectral index (BIS) were recorded and compared between two groups before administration (T0) and 1 min (T1), 2 min (T2), 3 min (T3), 4 min (T4), 5 min (T5) after the start of pumping drugs; the induction time, consciousness recovery time and orientation recovery time of two groups were observed; in addition, the injection pain score and adverse reactions were compared between the two groups. Result: There were significant differences in MAP, HR, SpO₂ and BIS at different time points between two groups (P<0.05); MAP and SpO₂ at T1, T2, T3, T4, T5 in Propofol group were lower than those at T0, the differences were statistically significant (P<0.05); MAP at T1 and T2 in Ciprofol group were lower than those at T0, and SpO₂ at T1, T2, T3, T4 were lower than those at T0, the differences were statistically significant (P<0.05); MAP and SpO₂ at T1, T2, T3, T4, T5 of Ciprofol group were higher than those of Propofol group, the differences were statistically significant (P<0.05); HR at T1 and T2 of two groups were higher than those at T0, the differences were statistically significant (P<0.05); HR at T1 and T2 of Ciprofol group were lower than those of Propofol group, the differences were statistically significant (P<0.05); BIS at T1, T2, T3, T4 and T5 of two groups were lower than those at T0, the differences were statistically significant (P<0.05). The induction time, consciousness recovery time and orientation recovery time of Ciprofol group were significantly shorter than those of Propofol group, and the differences were statistically significant (P<0.05 ). The visual analogue scale (VAS) score and incidence of hypotension and hypoxemia in Ciprofol group were lower than those in Propofol group, and the differences were statistically significant (P<0.05). Conclusion: The anesthetic efficacy of 0.4mg/kg Ciprofol was equivalent to

Objective: To explore the effect of the Guwei Jianpi Formula combined with nasal massage in the treatment of allergic rhinitis (AR) in children with lung-qi deficiency type. Method: A total of 70 children with AR admitted to Longyan Hospital of Traditional Chinese Medicine from September 2022 to September 2023 were included in the study and randomly divided into the combined group (n=35) and the control group (n=35). The control group was given conventional Western medical treatment, while the combined group was treated with the Guwei Jianpi Formula and nasal massage on this basis. The therapeutic effects, adverse reactions, clinical symptom and sign scores before and after treatment, serum immunoglobulin E (IgE), and eosinophil (EOS) levels of the two groups were compared. Result: The total effective rate of the combined group was higher than that of the control group (P<0.05). After treatment, the vital sign score, clinical symptoms, serum IgE and EOS levels in the combined group were lower than those in the control group (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion: The combination of Guwei Jianpi Formula and nasal massage in the treatment of AR children with lung-qi deficiency type can reduce the levels of serum IgE and EOS, improve clinical symptoms and signs, has a significant therapeutic effect, and is highly safe.

Objective: To explore the effect of Shujin Huoxue ointment combined with functional training on functional rehabilitation after knee unicondylar replacement. Method: 90 patients who underwent UKA in the Affiliated Hospital of Traditional Chinese Medicine of Xinjiang Medical University from January, 2022 to January, 2024 were selected. They were random divided into observation group and control group, 45 cases in each group. Under the concept of accelerated recovery from surgery, the control group received perioperative treatment and care, and the observation group was treated with Shujin and blood activating cream on the basis of the control group. The postoperative swelling degree (the difference between the 3-inch circumference of the affected limb above and below the patella), the postoperative pain degree (VAS score), and the knee joint function index (HSS score) were detected. Result: After treatment, the indexes of postoperative swelling degree and postoperative pain degree in both groups decreased (P<0.05), and the difference was statistically significant (P<0.05). HSS scores all increased, and the difference was statistically significant (P<0.05). Compared with the control group, the improvement in the observation group was more significant, with statistical significance (P<0.05). Conclusion: Shujin Huoxue ointment combined with functional training can significantly improve the clinical symptoms and joint function of patients after UKA operation, and reduce postoperative swelling and pain.

Objective: To analyze the effect of labetalol-based comprehensive treatment on gestational hypertension (PIH) patients in high-altitude areas. Method: A total of 84 PIH patients admitted to Qinghai Women and Children's Hospital from July 2023 to November 2024 were enrolled in this study and randomly divided into two groups, with 42 cases each. The control group received conventional antihypertensive treatment, while the experimental group was treated with labetalol-based comprehensive treatment. Both groups were treated for 14 days. The hypertension levels, pregnancy outcomes, biochemical test indicators, and clinical efficacy rates of the two groups were analyzed and compared. Result: Before treatment, both groups had high blood pressure levels. At 1 to 3 months post-treatment, blood pressure levels in both groups showed a downward trend, with the experimental group exhibiting lower diastolic/systolic blood pressure parameters compared to the control group, and the difference was statistically significant (P<0.05). The experimental group had fewer cases and a lower proportion of adverse pregnancy outcomes, with a statistically significant difference (P<0.05). No statistically significant difference was observed in blood biochemical indicators between the two groups before treatment (P>0.05). After treatment, the experimental group showed superior blood biochemical test results, with three indicator levels lower than those of the control group, and the difference was statistically significant (P<0.05). In the labetalol-based experimental group, the condition of PIH patients was effectively controlled, and the total efficacy rate was higher than that of the control group, with a statistically significant difference (P<0.05). Conclusion: Labetalol-based comprehensive treatment plays a significant role in controlling PIH symptoms, effectively reducing blood pressure, protecting vital organ functions, and improving maternal pregnancy outcomes.

Objective: To explore the application value of Mycobacterium tuberculosis RNA (TB RNA) combined with Mycobacterium tuberculosis/rifampicin resistance real-time fluorescent quantitative gene amplification (Xpert) detection technology. Method: A total of 150 patients with suspected pulmonary tuberculosis admitted to Hui 'an County Hospital of Quanzhou City from September 2022 to November 2024 were selected as the research subjects. All patients received sputum collection after admission, and the sputum was divided into three equal parts. Subsequently, TB RNA detection, Xpert detection, and combined detection of TB RNA and Xpert were conducted. Taking the clinical diagnostic results such as clinical symptoms, imaging examinations, sputum culture or histopathological examination as the gold standard, the positive detection rate, detection time and detection efficacy of TB RNA detection and Xpert detection alone and in combination for the diagnosis of pulmonary tuberculosis were compared. Result: The clinical diagnosis results show that among the 150 patients suspected of having pulmonary tuberculosis, a total of 129 patients were diagnosed with pulmonary tuberculosis. Compared with individual detection, the positive detection rate of the combined diagnosis of pulmonary tuberculosis by TB RNA detection method and Xpert detection method was higher (P<0.05). Moreover, it will not prolong the detection time and can reflect the live bacteria in sputum specimens and assess the drug resistance situation. The accuracy, sensitivity and specificity of the TB RNA detection method were 85.33%, 86.05% and 80.95% respectively, and those of the Xpert detection method were 86.67%, 87.60% and 80.95% respectively. The accuracy, sensitivity and specificity of the combined detection were 93.33%, 94.57% and 85.71% respectively. Conclusion: The combined diagnosis of pulmonary tuberculosis by TB RNA+Xpert detection method has high accuracy, sensitivity and specificity, considerable detection efficiency, and does not prolong the detection time. It can effectively evaluate the live bacteria and drug resistance of samples and is expected to provide an effective basis for the clinical diagnosis and treatment of pulmonary tuberculosis.

Objective: To explore the application effect of self-made Chinese herbal heat packs in mechanical phlebitis after percutaneously inserted centeral catheter (PICC) in cancer patients. Method: A total of 76 patients who underwent PICC replacement at Yangjiang People's Hospital from June 2023 to November 2024 were selected as the subjects and randomly divided into two groups by the envelope method, with 38 cases in each group. The control group was given routine care to help patients change dressings regularly, once a week. The observation group was combined with self-made traditional Chinese medicine hot compress packs for intervention. Both groups were continuously intervened for 7 days. The incidence of mechanical phlebitis, the degree of swelling, the degree of pain, the bleeding at the PICC puncture site, the quality of life and the incidence of complications were compared between the two groups. Result: The incidence of mechanical phlebitis in the observation group was lower than that in the control group, and the difference was statistically significant (P<0.05). After the intervention, the swelling and pain were relieved in both groups, and the bleeding area at the PICC puncture site was reduced. The scores of swelling and pain and the bleeding area at the PICC puncture site in the observation group were lower than those in the control group, and the difference was statistically significant (P<0.05). After interventien, the quality of life of the observation group was higher than that of the control group. The incidence of complications was lower than that of the control group, and the difference was statistically significant (P<0.05). Conclusion: The self-made traditional Chinese medicine hot compress bag has a good effect in the postoperative PICC surgery of tumor patients. It can reduce the incidence of mechanical phlebitis after surgery, help alleviate the degree of swelling and pain, reduce the bleeding and complication rate at the PICC puncture site, and improve the quality of life of patients.

Objective: To explore the application of magnetic resonance imaging (MRI) in the differential diagnosis of benign and malignant adnexal masses. Method: A total of 110 patients admitted to Longyan People's Hospital due to adnexal masses from January 2021 to December 2024 were selected as the research subjects and underwent MRI examinations. Taking the pathological examination results as the "gold standard", the benign and malignant conditions of adnexal masses detected by the two examination methods were compared. Result: The pathological results showed that among 110 patients, 76 were benign and 34 were diagnosed as malignant. MRI examination showed 75 benign cases and 31 malignant cases. Taking pathological diagnosis as the gold standard, the sensitivity of MRI in differentiating the benign and malignant of adnexal masses was 94.12%, the specificity was 96.05%, the accuracy rate was 95.45%, and the Kappa value was 0.894. The consistency of the two in diagnosing the benign and malignant of adnexal masses was relatively high. MRI has a relatively high detection rate for malignant teratoma, malignant ovarian choroidal stromal tumor, ovarian cyst and benign choroidal stromal tumor, all being 100.00%. The comparison of DWI signal intensity values and ADC values of benign and malignant cystic masses showed no statistically significant difference. (P>0.05). The DWI signal intensity value of malignant solid masses was higher than that of benign masses, while the ADC value was lower than that of benign masses, and the difference was statistically significant (P<0.05). Conclusion: MRI has a relatively high accuracy in differentiating benign and malignant adnexal masses and can provide a reliable basis for clinical intervention.

Thrombotic microangiopathy (TMA) is a group of diseases characterized by microvascular embolism. Its etiology and pathogenesis are complex and diverse, including primary thrombotic microangiopathy and secondary thrombotic microangiopathy. There is a close correlation between A Disintegrin and Metalloproteinase with Thrombospondin Type 1 motif, member 13 (ADAMTS13) and TMA. There are various methods for detecting its activity, and it has positive clinical significance in disease diagnosis, prognosis assessment, and disease differentiation. The role of ADAMTS13 in the diagnosis and treatment of thrombotic thrombocytopenic purpura is relatively clear, and it may also play an important role in other types of thrombotic microvascular diseases. The determination of its activity helps to distinguish different types of hemolytic uremic syndrome and other diseases, and provides a basis for treatment. The activity of ADAMTS13 has been reduced to varying degrees in thrombotic microvascular diseases such as disseminated intravascular coagulation, systemic lupus erythematosus nephritis, and severe liver injury, and it may serve as an auxiliary diagnostic indicator for such diseases.

Objective: To explore the therapeutic effect of the penetrating along meridians method combined with Qufeng Jiedu Huoluo Decoction in the treatment of acute peripheral facial paralysis. Method: A total of 80 acute peripheral facial paralysis patients were admitted to Renhuai People's Hospital between June 2022 and December 2024. According to the random envelope method, the patients were divided into the control group (n=40 cases, treated with conventional Western medicine combined with Qufeng Jiedu Huoluo Decoction) and the combined group (n=40 cases, treated with meridian puncture method on the basis of the control group). The therapeutic effects, TCM syndrome scores, facial nerve functions [House-Brackmann Facial Nerve Function Grading Scale (H-B), facial paralysis score Portmann], facial neuromuscular electromyography and adverse reactions were compared between the two groups. Result: Compared to the control group, the combined group demonstrated a significantly higher total effective rate (P<0.05). After 4 weeks of treatment, the combined group showed lower TCM syndrome scores,House-Brackmann (H-B) scores but higher Portmann scores compared to the control group (P<0.05). Additionally, the combined group exhibited lower compound muscle action potential (CMAP) amplitudes and blink reflex (BR) latencies than the control group (P<0.05). There was no statistically significant difference in the total incidence of adverse reactions between the two groups (P>0.05). Conclusion: The meridian penetration method combined with Qufeng Jiedu Huoluo Decoction has a significant effect in the treatment of acute peripheral facial paralysis. It can improve clinical symptoms, the functional level of the facial nerve, reduce facial nerve damage, and has good safety.

Objective: To analyze the application value of the combined intervention method of cluster nursing and barometric therapy for patients undergoing thoracic surgery, and to explore its preventive effect on deep vein thrombosis of the lower extremities. Method: A total of 102 patients who underwent thoracic surgery in the First Affiliated Hospital of Bengbu Medical University from July 2021 to July 2024 were selected as the research subjects and randomly divided into the control group (51 cases, receiving barometric therapy) and the observation group (51 cases, receiving combined intervention treatment of cluster nursing and barometric therapy).The peak blood flow, average blood flow velocity value, coagulation function, quality of life, occurrence of deep vein thrombosis in the lower extremities and satisfaction degree of femoral venous blood in the two groups were analyzed. Result: The peak blood flow and average blood flow velocity values of the femoral vein blood in the lower extremities showed an increasing trend when compared within the group before and after the intervention. When compared between groups after the intervention, the values in the observation group were higher than those in the control group (P<0.05). The levels of D-dimer (D-D) and fibrinogen (FIB) were compared within the groups before and after the intervention, showing a decreasing trend. When compared between groups after the intervention, the levels in the observation group were lower than those in the control group (P<0.05). The levels of activated partial thromboplastin time (APTT), prothrombin time (PT), and quality of life score were compared within the group before and after the intervention, showing an increasing trend. When compared between groups after the intervention, the observation group was higher than the control group (P<0.05). The occurrence rate for deep vein thrombosis of the lower extremities in the control group was higher than that in control group (P<0.05). The overall satisfaction of patients in the control group was lower than that in the observation group (P<0.05). Conclusion: For patients undergoing thoracic surgery, the combined intervention of cluster nursing and pneumatic therapy can effectively improve the blood flow in the lower extremities of patients, enhance their coagulation function, promote the improvement of their quality of life, and reduce the incidence of deep vein thrombosis in the lower extremities. Patients have a high satisfaction with this nursing intervention model.

Objective: To observe the clinical efficacy of the treatment of liver cancer with Xiaoji Huayu Pills combined with cyberknife and its influence on early recurrence and metastasis. Method: A total of 80 patients with primary liver cancer who had received cyberknife treatment from January 2021 to October 2023 were selected as the research subjects. And they were all admitted to Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine. They were randomly assigned to two group. The treatment group was also given oral Xiaoji Huayu Pills for a course of one year. The clinical effects and toxic side effects of the two groups were compared. Result: After half a year and one year of treatment, The treatment group showed a higher total effective rate for tumor reduction, with the difference being statistically significant (P<0.05). After one year of treatment, the treatment group's recurrence and metastasis rates was lower than the other with the difference being statistically significant (P<0.05). The serum vascular endothelial growth factor (VEGF) and alpha-fetoprotein (AFP) in both groups were down-regulated, and the expression of serum tumor protein 53 (P53) was up-regulated after treatment. Moreover, the treatment group's improvement was significantly greater, and this difference was statistically significant (P<0.05). A more significant improvement in both the traditional Chinese medicine symptom score and the quality of life score demonstrated in the treatment group, and the incidence of adverse reactions decreased by 20%. The difference was statistically significant (P<0.05). Conclusion: The combination of Xiaoji Huayu Pills and cyberknife in the treatment of liver cancer has a good clinical efficacy, effectively reduces the early recurrence and metastasis of tumors, and has good safety. It can be used for clinical promotion.

Objective: To explore the influence of multidimensional psychological support intervention on psychological stress and quality of life of postoperative patients with differentiated thyroid carcinoma during iodine 131 treatment. Method: 227 patients with differentiated thyroid carcinoma admitted to the nuclear medicine department of the 910th Hospital of the Joint Logistics Support Force of the Chinese People's Liberation Army (January 2019 to December 2023) were selected as the research object, and were divided into control group (n=113, routine nursing measures) and observation group (n=114, routine nursing measures combined with multidimensional psychological support intervention). Symptom CheckList-90 (SCL-90), Mishel Uncertainty in Illness Scale (MUIS), Medical Coping Modes Questionnaire (MCMQ) and Short Form Health Survey (SF-36) were used to evaluate the psychological stress response, disease uncertainty, coping style and quality of life of the two groups, and the differences of the above indexes were compared. Result: After the intervention, the scores of SCL-90, MUIS, avoidance and yield in both groups decreased, while the scores of face and SF-36 increased (P<0.05). After the intervention, the above indexes in the observation group were better than those in the control group (P<0.05). Conclusion: Multidimensional psychological support intervention can alleviate the psychological stress and uncertainty of disease in patients with differentiated thyroid carcinoma treated with iodine 131 after operation, improve their coping style and improve their quality of life.

Objective: To investigate the effect of keratoplasty on corneal function and visual acuity recovery in adolescent myopic patients. Method: The data of 120 adolescent myopia patients (186 eyes) who underwent visual acuity examination and correction at the First Affiliated Hospital of Xiamen University from July 2021 to January 2024 were retrospectively analyzed, and based on the different correction methods, they were divided into the control group (59 cases and 91 eyes wearing conventional myopia spectacles), and the plasmapheresis group (61 cases and 95 eyes wearing keratoplasty lenses continuously for 6 months). Corneal function and visual acuity were examined before, 1 week, 1 month, 3 months, and 6 months after lens wear and the number of corneal endothelial cells, corneal refractive error, intraocular pressure length, ocular axis, corneal thickness, anterior and posterior surface high-order aberration, and naked-eye visual acuity (UCVA) were compared between the two groups. Result: Corneal refraction, axial length, and corneal thickness were significantly reduced in both groups at 1 week, 1 month, 3 months, and 6 months after wearing the lenses, and the refraction was higher in the plastic lens group than in the control group at all time points, and the axial length and corneal thickness were lower than those in the control group, and the difference was statistically significant (P<0.05). The anterior surface high-order aberration was higher than that before lens wear in both groups at 1 week, 1 month, 3 months, and 6 months after lens wear, and the anterior surface high-order aberration was higher in the plastigraphy group than that in the control group at all time points, and the difference was statistically significant (P<0.05). The UCVA (logMA) of the plastic lens group was better than that of the control group at 1 week, 1 month, 3 months, and 6 months after lens wear, and the difference was statistically significant (P<0.05). Pearson's parametric correlation analysis showed that corneal refraction, corneal thickness, and ocular axis length were positively correlated with naked-eye distance visual acuity (UDVA), and anterior surface higher-order aberrations were negatively correlated with UDVA in myopia patients at 6 months after lens wear (P<0.05). Conclusion: The recovery of corneal function and visual acuity is most obvious 1 week after keratoplasty in adolescent myopic patients, while continuous wearing of keratoplasty lenses for 6 months can effectively improve patients' corneal function and naked-eye visual acuity.

Meniscus injury is a common knee joint disease. As a common sports injury, it often leads to symptoms such as knee joint pain and limited movement, seriously affecting patients' daily life and athletic ability. This literature reviews the latest research progress in the treatment of meniscus injury with both traditional Chinese and Western medicine. The exploration of treatment methods has always been a hot topic in the field of orthopedics. In recent years, significant progress has been made in the clinical application of integrated traditional Chinese and Western medicine in the treatment of meniscus injuries. This article explores the advantages and clinical application prospects of different treatment methods, aiming to provide references for clinical treatment.