2025 Volume 23 Issue 26 Published: 15 September 2025
  

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  • Article
    Analysis of the Application Effect of Labetalol-Based Comprehensive Treatment on Patients with Pregnancy-Induced Hypertension in Plateau Areas
    MA Yongping, MA Xiaoyun.
    2025, 23(26): 1-4. https://doi.org/10.14033/j.cnki.cfmr.2025.026.001
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    Objective: To analyze the effect of labetalol-based comprehensive treatment on gestational hypertension (PIH) patients in high-altitude areas. Method: A total of 84 PIH patients admitted to Qinghai Women and Children's Hospital from July 2023 to November 2024 were enrolled in this study and randomly divided into two groups, with 42 cases each. The control group received conventional antihypertensive treatment, while the experimental group was treated with labetalol-based comprehensive treatment. Both groups were treated for 14 days. The hypertension levels, pregnancy outcomes, biochemical test indicators, and clinical efficacy rates of the two groups were analyzed and compared. Result: Before treatment, both groups had high blood pressure levels. At 1 to 3 months post-treatment, blood pressure levels in both groups showed a downward trend, with the experimental group exhibiting lower diastolic/systolic blood pressure parameters compared to the control group, and the difference was statistically significant (P<0.05). The experimental group had fewer cases and a lower proportion of adverse pregnancy outcomes, with a statistically significant difference (P<0.05). No statistically significant difference was observed in blood biochemical indicators between the two groups before treatment (P>0.05). After treatment, the experimental group showed superior blood biochemical test results, with three indicator levels lower than those of the control group, and the difference was statistically significant (P<0.05). In the labetalol-based experimental group, the condition of PIH patients was effectively controlled, and the total efficacy rate was higher than that of the control group, with a statistically significant difference (P<0.05). Conclusion: Labetalol-based comprehensive treatment plays a significant role in controlling PIH symptoms, effectively reducing blood pressure, protecting vital organ functions, and improving maternal pregnancy outcomes.
  • Article
    Effect of Dopamine Combined with Phentolamine on Improvement of Symptoms and Myocardial Enzyme Profile in Children with Pneumonia Complicated with Heart Failure
    LIANG Nan, WU Hengjuan, YANG Hongyun.
    2025, 23(26): 4-7. https://doi.org/10.14033/j.cnki.cfmr.2025.026.002
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    Objective: To investigate the effect of dopamine combined with phentolamine in the treatment of children with pneumonia complicated with heart failure. Method: A total of 86 children with pneumonia complicated with heart failure admitted to the First Hospital of Hanbin District of Ankang from June 2022 to September 2024 were selected as the study objects. And they were divided into two groups according to the random number table method, with 43 cases in each group. The control group was treated with phentolamine, while the observation group was treated with dopamine. The effective rate, clinical indicators, improvement of myocardial enzymes and adverse reactions were compared between the two groups. Result: The effective rate of the observation group was higher than control group, and the difference was significant (P<0.05). The heart rate recovery time, respiratory recovery time, heart failure correction time, hospitalization time in observation group were shorter than those in control group, and the differences were statistically significant (P<0.05). After treatment, the levels of CK-MB, LDH, CK in the observation group were lower than those in control group, and the differences were statistically significant (P<0.05). Compared with the control group, the incidence of adverse reactions in the observation group was lower, the difference was significant (P<0.05). Conclusion: For children with pneumonia complicated with heart failure, the combination of phentolamine and dopamine can effectively improve the clinical efficacy, shorten the recovery time of the disease, promote the improvement of heart failure symptoms, reduce the level of myocardial enzyme spectrum indicators, and reduce the risk of adverse reactions.
  • Article
    Cross-Lagged Regression Analysis of Fear of Disease Progression and Sleep Quality in Patients after Cerebral Hemorrhage Surgery
    XUAN Mulian, LIU Lanbin, CHEN Jianbing.
    2025, 23(26): 8-13. https://doi.org/10.14033/j.cnki.cfmr.2025.026.003
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    Objective: Based on the cross-lag method, the changing trends and mutual influences of fear of disease progression and sleep quality in postoperative patients with cerebral hemorrhage over time were explored. Method: A total of 360 patients with cerebral hemorrhage who underwent surgical treatment at Zhongshan People's Hospital from January 2023 to January 2024 were selected as the research subjects. The Fear of Progression Questionnaire-Short Form (FoP-Q-SF) and the Pittsburgh Sleep Quality Score Index (PSQI) were used to evaluate and detect the fear of disease progression and sleep quality of patients at 24 hours after anesthesia and awakening (T1), 14 days after surgery (T2), and 1 month after surgery (T3), respectively. The Spearman method was used to analyze the correlation between fear of disease progression and sleep quality at different time points. The Mplus software was applied to construct a cross-lag analysis model to analyze the causal temporal relationship and direction of action between postoperative fear disease progression and sleep quality in patients with cerebral hemorrhage. Result: After excluding those who dropped out halfway and those with invalid data, a total of 338 patients completed the study. The FoP-Q-SF scores of 338 patients with cerebral hemorrhage at T1, T2 and T3 were (33.52±3.67), (28.24±2.96) and (25.37±2.41) respectively, and the PSQI scores were (15.36±2.14), (12.38±1.53) and (9.62±1.47) respectively. The results of the correlation analysis showed that the PSQI measured in the three times was positively correlated with the FoP-Q-SF score (P<0.05). The results of cross-hysteresis analysis showed that the FoP-Q-SF score of T1 in patients with cerebral hemorrhage could positively predict the T2PSQI score, and the T2FoP-Q-SF score could positively predict the T3PSQI score. The path coefficients were 0.242 and 0.359 respectively (P<0.05). The PSQI score of T1 can positively predict the FoP-Q-SF score of T2, and the PSQI score of T2 can positively predict the FOP-Q-SF score of T3. The path coefficients are 0.511 and 0.311 respectively (P<0.05). Conclusion: There is a cross-lagged effect between the fear of disease progression and sleep quality in patients with cerebral hemorrhage, suggesting a causal relationship between the two over multiple time spans. The relationship between the two can be utilized to formulate targeted postoperative care measures for patients, improving the prognosis quality of patients with cerebral hemorrhage.
  • Article
    Application of MRI in the Differential Diagnosis of Benign and Malignant Nature of Adnexal Masses
    CHEN Qikai.
    2025, 23(26): 13-16. https://doi.org/10.14033/j.cnki.cfmr.2025.026.004
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    Objective: To explore the application of magnetic resonance imaging (MRI) in the differential diagnosis of benign and malignant adnexal masses. Method: A total of 110 patients admitted to Longyan People's Hospital due to adnexal masses from January 2021 to December 2024 were selected as the research subjects and underwent MRI examinations. Taking the pathological examination results as the "gold standard", the benign and malignant conditions of adnexal masses detected by the two examination methods were compared. Result: The pathological results showed that among 110 patients, 76 were benign and 34 were diagnosed as malignant. MRI examination showed 75 benign cases and 31 malignant cases. Taking pathological diagnosis as the gold standard, the sensitivity of MRI in differentiating the benign and malignant of adnexal masses was 94.12%, the specificity was 96.05%, the accuracy rate was 95.45%, and the Kappa value was 0.894. The consistency of the two in diagnosing the benign and malignant of adnexal masses was relatively high. MRI has a relatively high detection rate for malignant teratoma, malignant ovarian choroidal stromal tumor, ovarian cyst and benign choroidal stromal tumor, all being 100.00%. The comparison of DWI signal intensity values and ADC values of benign and malignant cystic masses showed no statistically significant difference. (P>0.05). The DWI signal intensity value of malignant solid masses was higher than that of benign masses, while the ADC value was lower than that of benign masses, and the difference was statistically significant (P<0.05). Conclusion: MRI has a relatively high accuracy in differentiating benign and malignant adnexal masses and can provide a reliable basis for clinical intervention.
  • Article
    Effect of Intrauterine Balloon Tamponade Combined with Bilateral Uterine Artery Ligation on Blood Loss and Thromboelastogram Indexes in Patients with Postpartum Hemorrhage after Cesarean Section
    SHEN Sijin, SONG Lei.
    2025, 23(26): 17-20. https://doi.org/10.14033/j.cnki.cfmr.2025.026.005
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    Objective: To analyze the effects of intrauterine balloon tamponage (IUBT) combined with bilateral uterine artery ligation (BUAL) on blood loss and thromboelastogram (TEG) in patients with postpartum hemorrhage (PPH) after cesarean section. Method: Clinical data of 95 patients with PPH during cesarean section were collected from February 2023 to September 2024. They were divided into control group (48 cases) and observation group (47 cases) according to different treatment plans. The control group was hemostatic with BUAL regimen, and the observation group was hemostatic with combination BUAL regimen. The bleeding and blood transfusion, postoperative recovery indexes and adverse events were compared between the two groups. TEG indexes [reaction time (R time), coagulation time (K time), maximum thrombus elastic force (MA)] of the two groups were compared before and 12 h after surgery. Result: Compared with the control group, the total blood loss and blood transfusion in the observation group were lower, and the time of hemostasis, getting out of bed and staying in hospital were shorter (P<0.05). 12 h after operation, the R time and K time of both groups were shortened and the MA was increased, and the R time of observation group was shorter and the MA was higher than that of control group (P<0.05). The incidence of adverse events in the observation group was lower than that in the control group (P<0.05). Conclusion: IUBT combined with BUAL can improve hemostasis, reduce blood loss, improve coagulation function and promote postoperative recovery in PPH patients after cesarean section.
  • Article
    The Effect of Combined Treatment of Sodium Thiosulfate and Hemoperfusion on Skin Itching Score and Calcium and Phosphorus Metabolism in Patients with Uremia and Refractory Skin Itching
    ZHANG Shuilian, LIAO Yingfeng.
    2025, 23(26): 20-24. https://doi.org/10.14033/j.cnki.cfmr.2025.026.006
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    Objective: To analyze the effect of combined treatment of sodium thiosulfate and hemoperfusion (HP) on skin itching score and calcium and phosphorus metabolism in patients with uremia complicated with refractory skin itching. Method: 86 patients with uremia complicated with refractory skin itching admitted to Fujian Tingzhou Hospital frrom January 2022 to August 2023 were taken as the subjects. All selected cases were assigned to two groups (43 cases each) with random numerical table. The control group received routine hemodialysis treatment, while the observation group received a combination of sodium thiosulfate and HP hemodialysis treatment. The clinical efficacy, renal function indicators (BUN, Scr, Cys-C), calcium and phosphorus metabolism indicators (Ca, P, iPTH), inflammation indicators (CRP, PCT, SAA), 14-item uremic skin itching scale (14-tem UP-Dial Scale), and complications in both groups were compared. Result: The observation group obtained higher effective rate than the control group (P<0.05). The observation group had lower BUN, Scr, Cys-C, Ca, P, iPTH, CRP, PCT, SAA levels and 14-tem UP-Dial Scale score compared with the control group (P<0.05). The comparison of the incidence of complications in both groups expressed no statistical difference (P>0.05). Conclusion: Sodium thiosulfate combined with HP can improve renal function, promote calcium and phosphorus metabolism, reduce inflammation in the blood, alleviate skin itching symptoms and have a low risk of complicationsin patients with uremia complicated by refractory skin itching.
  • Article
    The Value of Combined Detection of Lipoprotein a, High-Sensitivity C-Reactive Protein and Homocysteine in the Diagnosis of Stroke
    WEI Zongkun, LIAO Bin, MO Si, HUANG Libing, XIANG Ping, QIN Xihuan.
    2025, 23(26): 25-27. https://doi.org/10.14033/j.cnki.cfmr.2025.026.007
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    Objective: This study aims to explore the application value of combined detection of lipoprotein a [Lp (a)], high-sensitivity C-reactive protein (hs-CRP), and homocysteine (Hcy) in the diagnosis of acute stroke. Method: 128 patients with acute stroke who were hospitalized in the Department of Neurology of the Eighth People's Hospital of Nanning from January 2022 to December 2024 were selected as the observation group, and another 116 healthy individuals undergoing physical examinations were selected as the control group. The levels of Lp(a), hs-CRP and Hcy in the serum of the two groups were detected. The collected data were statistically analyzed using SPSS 21.0 software, and the diagnostic validity of these biomarkers was evaluated. Result: The research results showed that the levels of Lp (a), hs-CRP and Hcy in the observation group were significantly higher than those in the healthy control group (P<0.05). In addition, the positive rate of the combined detection of these three indicators was significantly higher than that of the single indicator detection (P<0.05). Through analysis, it is indicated that the diagnostic efficacy of combined detection is superior to that of individual detection. The study also found that Lp (a) levels are associated with atherosclerotic status, hs-CRP can effectively reflect acute inflammatory responses, and Hcy is closely related to vascular endothelial dysfunction. Conclusion: To sum up, the combined detection of Lp (a), hs-CRP and Hcy has shown obvious clinical value in the early diagnosis and risk assessment of acute stroke, providing a scientific basis for the development of precision medicine.
    • Clinical practice
  • Clinical practice
    The Clinical Efficacy and Early Recurrence and Metastasis of Xiaoji Huayu Pill Combined with Cyberknife in Patients with Primary Liver Cancer
    MO Yuanjun, LU Xuquan, ZHOU Hui, TAN Zhiwei, ZHANG Xiaofei, LU Yunxin.
    2025, 23(26): 28-32. https://doi.org/10.14033/j.cnki.cfmr.2025.026.008
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    Objective: To observe the clinical efficacy of the treatment of liver cancer with Xiaoji Huayu Pills combined with cyberknife and its influence on early recurrence and metastasis. Method: A total of 80 patients with primary liver cancer who had received cyberknife treatment from January 2021 to October 2023 were selected as the research subjects. And they were all admitted to Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine. They were randomly assigned to two group. The treatment group was also given oral Xiaoji Huayu Pills for a course of one year. The clinical effects and toxic side effects of the two groups were compared. Result: After half a year and one year of treatment, The treatment group showed a higher total effective rate for tumor reduction, with the difference being statistically significant (P<0.05). After one year of treatment, the treatment group's recurrence and metastasis rates was lower than the other with the difference being statistically significant (P<0.05). The serum vascular endothelial growth factor (VEGF) and alpha-fetoprotein (AFP) in both groups were down-regulated, and the expression of serum tumor protein 53 (P53) was up-regulated after treatment. Moreover, the treatment group's improvement was significantly greater, and this difference was statistically significant (P<0.05). A more significant improvement in both the traditional Chinese medicine symptom score and the quality of life score demonstrated in the treatment group, and the incidence of adverse reactions decreased by 20%. The difference was statistically significant (P<0.05). Conclusion: The combination of Xiaoji Huayu Pills and cyberknife in the treatment of liver cancer has a good clinical efficacy, effectively reduces the early recurrence and metastasis of tumors, and has good safety. It can be used for clinical promotion.
  • Clinical practice
    The Clinical Effect of Electroacupuncture and Chinese Herbal Fumigation in Patients with Ankle Fractures after Surgery
    DAI Shaochuan.
    2025, 23(26): 32-35. https://doi.org/10.14033/j.cnki.cfmr.2025.026.009
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    Objective: To explore the application value of electroacupuncture combined with Chinese herbal fumigation in patients with ankle fractures. Method: A total of 94 patients with ankle fractures admitted to the First Affiliated Hospital of Xiamen University from August 2019 to August 2024 were selected as the research subjects. Using the random numerical table, all selected patients were assigned to two groups (47 cases each). The patients of control group were provided with conventional treatment, while the observation group was treated with electroacupuncture combined with Chinese herbal fumigation on the basis of the control group. The degrees of pain and swelling, fracture healing, ankle joint function, incidence of complications and quality of life were compared between the two groups. Result: Compared with the control group, the observation group had lower degree of pain and swelling, shorter fracture healing time, higher score of ankle joint function, greater ankle joint range of motion, fewer complications, and higher score of quality of life after treatment (P<0.05). Conclusion: Electroacupuncture combined with Chinese herbal fumigation can alleviate postoperative pain and swelling in patients with ankle fractures, accelerate fracture healing, reduce complications, and promote the recovery of ankle joint function and the improvement of quality of life.
  • Clinical practice
    The Effect of Modified Buzhong Yiqi Decoction Combined with Acupuncture in Patients with Qi Deficiency Type of Postpartum Stress Urinary Incontinence
    YAN Zhoudan.
    2025, 23(26): 36-39. https://doi.org/10.14033/j.cnki.cfmr.2025.026.010
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    Objective: To explore the application value of modified Buzhong Yiqi Decoction combined with acupuncture in postpartum stress urinary incontinence of qi deficiency type. Method: 80 patients with postpartum stress urinary incontinence of qi deficiency type admitted to Xuzhou Central Hospital from April 2023 to April 2024 were taken as the objects. And they were assigned to two groups with random numerical table. The patients of control group were administrated electrical stimulation biofeedback therapy, and on this basis, the patients of observation group additionally took modified Buzhong Yiqi Decoction and acupuncture. The comparisons were made on clinical efficacy, pelvic floor surface electromyography values, TCM syndrome scores and pelvic floor muscle strength in both groups. Result: The observation group obtained higher overall effective rate than the control group (P<0.05). The observation group showed lower average values of the pre-resting stage and the post-resting stage compared to the control group, and the observation group had higher maximum values of the fast muscle (type Ⅱ fiber) stage, the average values of the slow muscle (type Ⅰ fiber) stage, and the average values of the endurance test stage than the control group after treatment (P<0.05). Compared with the control group, the observation group achieved lower scores of urinary incontinence, soreness and weakness of the waist and knees, lower abdominal distension and incomplete drainage after urination, and higher pelvic floor muscle strength (P<0.05). Conclusion: The modified Buzhong Yiqi Decoction combined with acupuncture has a definite effect in the treatment of postpartum stress urinary incontinence of qi deficiency type. It can improve the pelvic floor surface electromyography value and TCM syndrome score of patients, and enhance pelvic floor muscle strength.
  • Clinical practice
    Effect of Ivabradine Early Intervention on Patients with Right Heart Failure
    HUANG Fei, XIE Xiaoming, ZHENG Chongzhou, CHEN Chunmei.
    2025, 23(26): 40-43. https://doi.org/10.14033/j.cnki.cfmr.2025.026.011
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    Objective: Taking patients with right heart failure as the observation subjects and early intervention with ivabradine as the treatment method, the clinical effects of the above treatment methods on the observation subjects were analyzed and discussed. Method: The study took 100 cases of right heart failure received by the Affiliated Hospital of Guangdong Medical University from July 2022 to December 2023 as samples and divided the samples into two equal groups based on the time of admission. Among them, the cases admitted to the hospital from July 2022 to March 2023 were set as the control group, including a total of 50 cases, and were treated with levosimendan. Cases admitted to the hospital from April to December 2023 were regarded as the observation group, which also included 50 cases. On the basis of the control group, early intervention with ivabradine was combined. The clinical efficacy, cardiac function indicators before and after treatment, and the incidence of adverse reactions of the two groups were compared. Result: In terms of the comparison of the total clinical effective rate, compared with the control group, the observation group showed a higher effective rate value, and the difference was statistically significant (P<0.05). After treatment, in the comparison of left ventricular end-systolic diameter (LVESD) and left ventricular end-diastolic diameter (LVEDD), the observation group was relatively lower compared with the control group. Moreover, in the comparison of left ventricular ejection fraction (LVEF), the observation group was relatively higher compared with the control group, and the differences were statistically significant (P<0.05). In terms of the comparison of the total clinical effective rate, compared with the control group, the observation group showed a higher effective rate value, and the difference was statistically significant(P>0.05). Conclusion: For right heart failure, the application of ivabradine intervention measures in the early stage can achieve quite ideal therapeutic effects, which is conducive to improving cardiac function indicators and has good safety.
  • Clinical practice
    Clinical Study on the Treatment of Anemia in Pregnant Women with Protein Succinate Iron Oral Solution Combined with Vitamin D
    WU Ranhong.
    2025, 23(26): 43-46. https://doi.org/10.14033/j.cnki.cfmr.2025.026.012
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    Objective: To investigate the effect of iron protein succinate oral solution combined with vitamin D on anemia in pregnant women. Method: A total of 122 patients with gestational anemia who attended Pizhou Hospital of Traditional Chinese Medicine from September 2021 to May 2024 were selected as the study objects and divided into two groups according to the random number table method, with 61 cases in each group. The control group was treated with traditional iron, and the experimental group was treated with iron protein succinate oral solution combined with vitamin D. The clinical efficacy, blood biochemical indexes, iron metabolism indexes and incidence of adverse pregnancy outcomes were compared between the two groups. Result: After treatment, the clinical efficacy, red blood cell count, hemoglobin, hematocrit, mean corpuscular volume, serum ferritin, transferrin saturation, and serum iron level in the experimental group were higher than those in the control group, and the incidence of adverse pregnancy outcomes was lower than that in the control group, and the difference was statistically significant (P<0.05). Conclusion: Iron protein succinate oral solution combined with vitamin D in the treatment of pregnant women can effectively correct anemia, improve iron metabolism and pregnancy outcomes, and is worthy of clinical promotion.
  • Clinical practice
    Effect of rhEGF Combined with Sodium Hyaluronate Eye Drops on Dry Eye after Phacoemulsification of Cataract
    ZHANG Shaobin.
    2025, 23(26): 47-50. https://doi.org/10.14033/j.cnki.cfmr.2025.026.013
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    Objective: Evaluating the therapeutic efficacy of recombinant human epidermal growth factor (rhEGF) in synergistic combination with sodium hyaluronate for the management of post-phacoemulsification dry eye (PKPD). Method: The clinical cases of 100 PKPD patients admitted to Fuzhou First General Hospital across from September 2022 to September 2024 were selected. The study adopted the random number table method for grouping. The observation group and the control group each included 50 patients. The control group was patients treated with sodium hyaluronate eye dreps while the intervention group was treated with rhEGF on the basis of controll group. Tear film stability, the condition of corneal epithelial defect, condition, tear secretion, response rate and adverse reaction were assessed. Result: The control group exhibited significantly longer duration of ocular dryness, burning sensation, eye pain, and photophobia symptoms compared to the observation group, with statistically significant differences (P<0.05). Pretreatment assessments showed no significant intergroup differences in tear film stability, corneal epithelial defect status, disease severity, or tear secretion function (P>0.05). Post-treatment evaluations revealed significantly greater reductions in Ocular Surface Disease Index (OSDI) and fluorescein staining (FL) scores, along with more substantial improvements in Schirmer's test (SIt) and tear film breakup time (BUT) in the observation group versus controls (P<0.05). Efficacy analysis demonstrated a significantly higher treatment response rate in the observation group (98.00%) compared to the control group (86.00%) (P<0.05). Safety assessment indicated no statistically significant difference in the incidence of local reactions including eyelid itching, conjunctival congestion, and ocular redness between groups (P>0.05). Conclusion: The dual-action mechanism of rhEGF and sodium hyaluronate promotes more rapid clinical symptom abatement in affected patients, alleviate the condition, repair corneal epithelial defects, enhance tear secretion function, prolong tear film break-up time, and has good therapeutic effect and high safety.
  • Clinical practice
    The Effect of Catgut Embedding at the Beiyu Acupoint on Sleep Quality and Serum 5-HT and DA Levels in Patients with Sub-Health Status of Insomnia
    LU Meng, HE Lei, ZHU Yulian, SONG Wenping.
    2025, 23(26): 51-54. https://doi.org/10.14033/j.cnki.cfmr.2025.026.014
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    Objective: To explore the application value of catgut embedding at the Beiyu acupoint in patients with sub-health status of insomnia. Method: 80 patients with sub-health status of insomnia who visited Lianyungang Hospital of Traditional Chinese Medicine from October 2022 to October 2024 were selected as the research subjects and divided into two groups according to the random number table method, with 40 cases in each group. The patients of control group were administrated routine western medicine, and on this basis, the patients of observation group additionally took catgut embedding at the Beiyu acupoint. The sleep quality, serological indicators, negative emotions and quality of life of the two groups were compared. Result: The comparisons of sleep quality, serological indicators, negative emotions and quality of life in both groups before treatment showed no statistical difference (P>0.05). The observation group had lower scores of Pittsburgh Sleep Quality Index (PSQI), dopamine (DA), Self-Rating Anxiety Scale (SAS), and Self-rating Depression Scale (SDS), higher 5-hydroxytryptamine (5-HT) and the psychology of World Health Organization Quality of Life Scale (WHOQOL-100) compared with the control group after treatment (P<0.05). Conclusion: Catgut embedding at the Beiyu acupoint can improve the sleep quality of patients with sub-health status of insomnia, alleviate negative emotions, and enhance the quality of life.
  • Clinical practice
    The Effect of Aripiprazole Combined with Lithium Carbonate on Patients with Schizophrenia
    XU Shan.
    2025, 23(26): 54-57. https://doi.org/10.14033/j.cnki.cfmr.2025.026.015
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    Objective: Exploring the efficacy of combination therapy with aripiprazole and lithium carbonate in patients with schizophrenia. Method: 80 patients with schizophrenia admitted to the Third Hospital of Nanping City from January 2023 to May 2024 were selected as the study objects and randomly divided into an observation group (40 cases, treated with aripiprazole combined with lithium carbonate) and a control group (40 cases, treated with aripiprazole). The mental symptoms, neurotransmitters [dopamine (DA), norepinephrine (NE)], aggressive behaviors, quality of life and adverse reactions of the two groups were compared. Result: After 12 weeks of treatment, the observation group had lower scores in all dimensions and total scores of the Positive and Negative Symptom Scale, as well as lower scores in the Revised Explicit Aggressive Behavior Scale (MOAS) and DA compared to the control group. The NE level and Activities of Daily Living (ADL) score were higher in the observation group than in the control group, and the differences were statistically significant (P<0.05). There was no statistically significant difference in adverse reactions between the two groups (P>0.05). Conclusion: The combination of aripiprazole and lithium carbonate can not only regulate the neurotransmitter metabolism levels of patients with schizophrenia, but also alleviate their mental symptoms and aggressive behavior, while helping to improve their quality of life, with acceptable safety.
  • Clinical practice
    The Combined Application of Nebulized Terbutaline Inhalation and Sequential Azithromycin Therapy on Serum Inflammatory Factors and Lung Function in Patients with Mycoplasma Pneumonia
    PAN Xiaoping, ZHENG Juan, GAO Bing, YANG Yanhui.
    2025, 23(26): 58-61. https://doi.org/10.14033/j.cnki.cfmr.2025.026.016
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    Objective: To explore the effect of the combined application of terbutaline nebulized inhalation and azithromycin sequential therapy on patients with mycoplasma pneumonia (MPP). Method: A total of 82 patients with MPP admitted to Huanggang Maternal and Child Health Hospital from June 2021 to June 2024 were selected. According to the random number table method, the patients were divided into the control group (n=41, treated with sequential azithromycin therapy) and the observation group (n=41, treated with terbutaline nebulized inhalation on the basis of the treatment in the control group). The treatment course of both groups was 14 days. The clinical efficacy, symptom relief time, serum inflammatory factors, lung function and adverse reactions of the two groups were compared. Result: The total effective rate of treatment in the observation group (95.12%) was higher than that in the control group (78.05%). The relief time of fever symptoms in the observation group was (2.69±0.42) days, that of cough symptoms was (5.11±1.01) days, that of pulmonary rales symptoms was (5.08±1.02) days, and that of wheezing symptoms was (2.01±0.11) days, which were shorter than those in the control group. After treatment in the observation group, interleukin-6 (IL-6) was (15.54±2.11) pg/mL, C-reactive protein (CRP) was (6.04±1.08) mg/L, tumor necrosis factor -α (TNF-α) was (8.11±1.21) ng/L, and interferon -γ (INF-γ) was (14.04±2.05) ng/mL, which were lower than those of the control group. After treatment, the maximum expiratory flow rate (PEF) (3.39±0.49) L/min, forced vital capacity (FVC) (3.72±0.31) L, midcourse expiratory flow rate (MMEF) (1.85±0.25) L/S, and forced expiratory volume in one second (FEV1) (1.40±0.25) L in the observation group were higher than those in the control group. The difference was statistically significant (P<0.05). There was no statistically significant difference in adverse reactions between the two groups (P>0.05). Conclusion: In patients with MPP, the sequential therapy of terbutaline nebulized inhalation combined with azithromycin has a significant effect in terms of disappearance of clinical symptoms, reduction of inflammatory response, improvement of lung function, etc., and has a relatively high safety.
  • Clinical practice
    The Therapeutic Effects of Budesonide-Formoterol in Patients with Chronic Obstructive Pulmonary Disease and Respiratory Failure and Its Relationship with Oxidative Stress Responses
    ZHOU Rong, FANG Yan, XIE Jinfeng, CHEN Qi, WEN Xiaomin, GONG Shaoxiang, GONG Xiaoyan.
    2025, 23(26): 62-66. https://doi.org/10.14033/j.cnki.cfmr.2025.026.017
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    Objective: To investigate the efficacy and safety of budesonide formoterol combination inhalation therapy in patients with chronic obstructive pulmonary disease (COPD) with respiratory failure, with particular attention to changes in oxidative stress, and to assess its impact on clinical symptoms, lung function, and inflammatory factor levels. Method: The clinical data of 100 patients with COPD with respiratory failure admitted to the First Affiliated Hospital of Gannan Medical University from January 2023 to December 2024 were retrospectively analysed, and were divided into the experimental group and the control group according to the different treatment protocols, with 50 cases each. On the basis of conventional treatment, the experimental group was treated with budesonide formoterol combined inhalation therapy, and the control group was not treated with budesonide formoterol combined inhalation therapy. Lung function, arterial blood gases, levels of inflammatory factors, and drug safety were assessed in the 2 groups after 10 days of treatment. Result: The experimental group was significantly better than the control group in improving lung function, reducing dyspnoea, increasing PaO2 and reducing PaCO2. Inflammatory factor levels decreased significantly in the experimental group. During treatment, the experimental group had fewer adverse drug reactions and the side effects were mainly mild local discomfort. Conclusion: Budesonide-formoterol combination inhalation therapy showed favorable clinical efficacy in patients with COPD and respiratory failure, effectively improving lung function, alleviating symptoms, and suppressing inflammation. This treatment regimen has a high safety profile.
    • Medical technology and clinical
  • Medical technology and clinical
    Analysis of the Application Value of Magnetic Resonance Silent Sequence in Intracranial Arterial Angiography
    XU Chao, WANG Di.
    2025, 23(26): 67-70. https://doi.org/10.14033/j.cnki.cfmr.2025.026.018
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: To analyze the application value of magnetic resonance silent sequences in intracranial arterial angiography. Method: 80 patients with intracranial artery diseases admitted to Guizhou Provincial People's Hospital from January 2024 to December 2024 were selected as the research subjects. They were divided into the control group and the observation group by random number table method, with 40 cases in each group. The control group was examined and diagnosed using the conventional magnetic resonance sequence, while the observation group was examined and diagnosed using the silent magnetic resonance sequence. The signal-to-noise ratio, contrast-to-noise ratio, examination comfort score, and excellent and good rate of image quality of the internal carotid artery and basilar artery were compared between the two groups. Result: The signal-to-noise ratio and contrast-to-noise ratio of the internal carotid artery and basilar artery in the observation group were lower than those in the control group. The comfort score of the observation group was higher than that of the control group, and the excellent and good rate of the observer image quality was higher than that of the control group. The differences were statistically significant (P<0.05). Conclusion: The application value of silent magnetic resonance sequences in intracranial artery angiography is significant. It can not only reduce the signal-to-noise ratio and contrast-to-noise ratio of the internal carotid artery and basilar artery in patients, but also improve the comfort of patients during the examination and the quality of images, thereby providing a reliable basis for intracranial artery angiography.
  • Medical technology and clinical
    Application of TB RNA Combined with Xpert Detection Technology in the Clinical Diagnosis of Pulmonary Tuberculosis
    CHEN Weibin, ZHANG Chuanyi, WANG Weibin, ZHANG Mingyi.
    2025, 23(26): 70-73. https://doi.org/10.14033/j.cnki.cfmr.2025.026.019
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: To explore the application value of Mycobacterium tuberculosis RNA (TB RNA) combined with Mycobacterium tuberculosis/rifampicin resistance real-time fluorescent quantitative gene amplification (Xpert) detection technology. Method: A total of 150 patients with suspected pulmonary tuberculosis admitted to Hui 'an County Hospital of Quanzhou City from September 2022 to November 2024 were selected as the research subjects. All patients received sputum collection after admission, and the sputum was divided into three equal parts. Subsequently, TB RNA detection, Xpert detection, and combined detection of TB RNA and Xpert were conducted. Taking the clinical diagnostic results such as clinical symptoms, imaging examinations, sputum culture or histopathological examination as the gold standard, the positive detection rate, detection time and detection efficacy of TB RNA detection and Xpert detection alone and in combination for the diagnosis of pulmonary tuberculosis were compared. Result: The clinical diagnosis results show that among the 150 patients suspected of having pulmonary tuberculosis, a total of 129 patients were diagnosed with pulmonary tuberculosis. Compared with individual detection, the positive detection rate of the combined diagnosis of pulmonary tuberculosis by TB RNA detection method and Xpert detection method was higher (P<0.05). Moreover, it will not prolong the detection time and can reflect the live bacteria in sputum specimens and assess the drug resistance situation. The accuracy, sensitivity and specificity of the TB RNA detection method were 85.33%, 86.05% and 80.95% respectively, and those of the Xpert detection method were 86.67%, 87.60% and 80.95% respectively. The accuracy, sensitivity and specificity of the combined detection were 93.33%, 94.57% and 85.71% respectively. Conclusion: The combined diagnosis of pulmonary tuberculosis by TB RNA+Xpert detection method has high accuracy, sensitivity and specificity, considerable detection efficiency, and does not prolong the detection time. It can effectively evaluate the live bacteria and drug resistance of samples and is expected to provide an effective basis for the clinical diagnosis and treatment of pulmonary tuberculosis.
  • Medical technology and clinical
    The Effect of Arthroscopic Assisted Ilizarov Traction Technique on Joint Range of Motion, AOS Score, and Inflammatory Factors in Patients with Ankle Traumatic Osteoarthritis
    FAN Youbin.
    2025, 23(26): 74-77. https://doi.org/10.14033/j.cnki.cfmr.2025.026.020
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: To explore the effects of arthroscopic-assisted Ilizarov stretch technique on joint range of motion, ankle osteoarthritis (AOS) score and inflammatory factors in patients with post-traumatic osteoarthritis of the ankle (PTOA). Method: A retrospective analysis was conducted on the diagnosis and treatment data of 67 patients with PTOA who underwent surgical treatment at Xiamen Fifth Hospital from January 2020 to December 2023. Among them, 35 cases were treated with arthroscopic-assisted Ilizarov traction technique (Group A), and 32 cases were treated with traditional open ankle arthroplasty (Group B). The general conditions of the surgery and the levels of serum inflammatory factors before and after the surgery were compared between the two groups. The patients were followed up for 6 months after the surgery. The AOS score and joint range of motion at the last follow-up were recorded, and the therapeutic effect was evaluated. Result: The operation time, intraoperative blood loss and hospital stay in group A were significantly less than those in group B, and the incidence of complications was significantly lower than that in group B. The differences were statistically significant (P<0.05). Half a month after the operation, the indicators of interleukin (IL) -6, C-reactive protein (CRP), and tumor necrosis factor (TNF) -α in group A were significantly lower than those in group B. At the last follow-up, the AOS score and joint range of motion in group A were significantly greater than those in group B, and the differences were statistically significant (P<0.05). The excellent and good rate of group A was significantly higher than that of group B, and the difference was statistically significant (P<0.05). Conclusion: Compared with open fusion in the treatment of PTOA, arthroscopic-assisted Ilizarov stretch technique can quickly restore the ankle function of patients and reduce inflammatory responses. It is an effective and safe method for the treatment of traumatic ankle osteoarthritis.
  • Medical technology and clinical
    Comparative Study of Thoracoscopic Single Segmentectomy and Combined Segmentectomy for the Treatment of Non-Small Cell Lung Cancer with a Diameter of ≤2 cm
    LUO Liang, YANG Libao, LIAN Baozhen.
    2025, 23(26): 77-80. https://doi.org/10.14033/j.cnki.cfmr.2025.026.021
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: To explore the comparative effects of thoracoscopic single segmental lung resection and combined segmental lung resection in the treatment of non-small cell lung cancer (NSCLC) with a diameter of ≤2 cm. Method: A total of 80 patients with NSCLC (diameter ≤2 cm) admitted to the Second Hospital of Sanming City from January 2021 to December 2024 were selected as the research subjects. They were divided into the combined group (42 cases, undergoing combined pulmonary subsegment resection) and the single resection group (38 cases, undergoing thoracoscopic single pulmonary subsegment resection) according to different surgical methods. Observe and compare the perioperative indicators, pain sensation and the occurrence of postoperative complications of the two groups. Result: Compared with the combination group, the single incision group had shorter hospitalization and drainage tube retention time, surgical duration, and cutting edge distance, and less intraoperative bleeding, with statistically significant differences (P<0.05). Compared with preoperative, VAS scores decreased in both groups 3 days after surgery, and the single incision group was lower than the combination group, with a statistically significant difference (P<0.05). 80 cases of NSCLC (diameter ≤2 cm) patients with postoperative pathological margins were all negative. There was no statistically significant difference in the surgical pathological types and postoperative complication rates between the two groups (P>0.05). Conclusion: Compared with combined pulmonary subsegmentectomy, patients undergoing single pulmonary subsegmentectomy have shorter hospital stays, operation duration, indwelling time of drainage tubes, less intraoperative blood loss, and less postoperative pain. Moreover, combined pulmonary subsegmentectomy has more advantages in complete tumor resection.
  • Medical technology and clinical
    Clinical Comparative Study of Endoscopic Surgery Via Axillary and Thoracic Breast Approach and Microscopic Assisted Open Surgery for Differentiated Thyroid Cancer
    ZHAN Bin, WEI Yongjun, GAO Kai, HUANG Zhiwei, TAI Junhu.
    2025, 23(26): 81-83. https://doi.org/10.14033/j.cnki.cfmr.2025.026.022
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: To compare the clinical efficacy of two endoscopic approaches and microscopic-assisted open surgery in the treatment of differentiated thyroid cancer. Method: A total of 90 patients with differentiated thyroid cancer admitted to the Second Affiliated Hospital of Xiamen Medical College from May 2019 to May 2024 were selected as the research subjects and divided into three groups according to the surgical methods, with 30 cases in each group. Group A received open thyroid surgery assisted by a microscope, Group B received endoscopic thyroid surgery via the thoracobreast approach, and Group C received endoscopic thyroid surgery via the axillary approach. The clinical data, operation time, intraoperative blood loss, the number of lymph node dissections in the central area and the number of positive lymph nodes, the total postoperative drainage volume, the number of days discharged after operation, cosmetic satisfaction, and complications of the three groups were compared. Result: There was no statistically significant difference in the operation time, intraoperative blood loss, the number of central lymph node dissections and the number of positive lymph nodes among the three groups (P>0.05). There was no statistically significant difference in the postoperative discharge days and postoperative complications among the three groups (P>0.05). After the operation, the total drainage volume was greater in group B than in group C than in group A, and the difference was statistically significant (P<0.05). After the operation, the cosmetic satisfaction rate was greater in group C than in Group B and greater in Group A, and the difference was statistically significant (P<0.05). Conclusion: The three surgical methods have similar surgical effects in the treatment of differentiated thyroid cancer. Laparoscopic surgery via axillary and thoracolumbral approaches has better cosmetic effects compared with open surgery assisted by a microscope.
    • Modern nursing
  • Modern nursing
    Research and Development on the Application of Cardiac Rehabilitation in Transcatheter Aortic Valve Replacement
    CUI Jianfeng, MA Li, LIN Xiaoyan, ZHANG Qingfen.
    2025, 23(26): 84-87. https://doi.org/10.14033/j.cnki.cfmr.2025.026.023
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: The application effect of cardiac rehabilitation (CR) in transcatheter aortic valve replacement (TAVR) was explored and analyzed. Method: A total of 150 patients with aortic stenosis (AS) admitted to Gaozhou People's Hospital from April 2023 to January 2025 were selected as the research subjects. All patients were treated with TAVR. The patients were randomly divided into two groups by the random number table method. The control group and the observation group were respectively given conventional nursing and CR nursing intervention, and the intervention effects of the two groups were compared. Result: After the intervention, the levels of left ventricular ejection fraction (LVEF) in both groups increased to a certain extent, while the levels of left ventricular end-diastolic diameter (LVEDD) and left ventricular end-systolic diameter (LVESD) decreased. Moreover, compared with the control group, it can be seen that the level of LVEF in the observation group was higher, while the levels of LVEDD and LVESD were lower, and the difference was statistically significant (P<0.05). After the intervention, the 6-minute walk test (6MWT) and the score of the Minnesota Heart Failure Quality of Life Scale (MLHFQ) of both groups of patients increased to varying degrees. Moreover, compared with the control group, it can be seen that the scores of 6MWT and MLHFQ in the observation group were significantly higher, and the difference was statistically significant (P<0.05). Compared with the control group, the all-cause mortality rate and the total incidence of adverse cardiovascular events in the observation group were significantly lower, and the difference was statistically significant (P<0.05). Conclusion: Providing CR care to patients with AS during TAVR has a significant effect. It can effectively improve the cardiac function of patients, promote the recovery of their exercise capacity and quality of life, and also reduce the risk of all-cause mortality and adverse cardiovascular events after surgery.
  • Modern nursing
    Clinical Observation of Comprehensive Rehabilitation Therapy Combined with Soft Muscle Spasmodic Acupuncture for Treating Post Stroke Hemiplegia
    CHEN Zhiguang, ZENG Honghui, CAI Tingyu.
    2025, 23(26): 88-91. https://doi.org/10.14033/j.cnki.cfmr.2025.026.024
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: To observe the combined application effect of soft muscle and antispasmodic acupuncture and comprehensive rehabilitation therapy in the clinical treatment of post-stroke hemiplegia. Method: Ninety patients with post-stroke hemiplegia admitted to Quanzhou Traditional Chinese Medicine Hospital from June 2023 to May 2024 were randomly divided into two groups using the random envelope method. Both groups received routine treatment, with the control group (45 cases) receiving comprehensive rehabilitation therapy and the study group (45 cases) receiving combined treatment with soft muscle antispasmodic acupuncture. The clinical efficacy of the two groups was compared. Result: The clinical efficacy and life index (BI), limb motor function (FMA), functional walking ability (FAC), and Berg balance ability (BBS) scores of the study group were higher than those of the control group, while the TCM syndrome score was lower than that of the control group (P<0.05). Conclusion: In the clinical treatment of post-stroke hemiplegia, the combination of soft muscle antispasmodic acupuncture and comprehensive rehabilitation therapy can improve patients' limb movement function, balance, and walking ability.
  • Modern nursing
    The Effect of Bundled Nursing Combined with Psychological Nursing on Patients Treated with EICU Severe CRRT Machine
    CHEN Huaping.
    2025, 23(26): 91-94. https://doi.org/10.14033/j.cnki.cfmr.2025.026.025
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: To explore the clinical effect of implementing cluster nursing combined with psychological nursing intervention for patients in the EICU who are undergoing continuous renal replacement therapy (CRRT) treatment. Method: A total of 100 patients admitted to the Sanming First Hospital from January 2021 to January 2024 for CRRT machine treatment were included as the analysis subjects. They were randomly grouped by a random number table and divided into a control group and an observation group. During the CRRT machine treatment period, they were respectively provided with cluster care and cluster care combined with psychological care intervention, with 50 cases in each group. The differences in psychological state, blood gas indicators and vital signs data between the two groups of patients were analyzed. Result: After the intervention, the evaluation scores of the anxiety and depression scales in the observation group were lower than those in the control group, and the difference was statistically significant (P<0.05). After the intervention, the detection data of arterial partial pressure of oxygen (PaO2) and arterial partial pressure of carbon dioxide (PaCO2) in the observation group were better than those in the control group, and the difference was statistically significant (P<0.05). After the intervention, the detection data of heart rate, respiratory rate and blood pressure in the observation group were better than those in the control group, and the difference was statistically significant (P<0.05). Conclusion: For critically ill patients in the EICU treated with CRRT machines, on the basis of implementing targeted and bundled care, psychological care that is conducive to stabilizing the patients' emotions can better ensure the implementation of various medical and nursing measures, thereby guaranteeing the intervention effect.
  • Modern nursing
    Evaluation of the Effect of Bundle Nursing Combined with Pneumatic Therapy in Thoracic Surgery for Preventing Deep Vein Thrombosis in the Lower Limbs
    WU Wu.
    2025, 23(26): 95-99. https://doi.org/10.14033/j.cnki.cfmr.2025.026.026
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: To analyze the application value of the combined intervention method of cluster nursing and barometric therapy for patients undergoing thoracic surgery, and to explore its preventive effect on deep vein thrombosis of the lower extremities. Method: A total of 102 patients who underwent thoracic surgery in the First Affiliated Hospital of Bengbu Medical University from July 2021 to July 2024 were selected as the research subjects and randomly divided into the control group (51 cases, receiving barometric therapy) and the observation group (51 cases, receiving combined intervention treatment of cluster nursing and barometric therapy).The peak blood flow, average blood flow velocity value, coagulation function, quality of life, occurrence of deep vein thrombosis in the lower extremities and satisfaction degree of femoral venous blood in the two groups were analyzed. Result: The peak blood flow and average blood flow velocity values of the femoral vein blood in the lower extremities showed an increasing trend when compared within the group before and after the intervention. When compared between groups after the intervention, the values in the observation group were higher than those in the control group (P<0.05). The levels of D-dimer (D-D) and fibrinogen (FIB) were compared within the groups before and after the intervention, showing a decreasing trend. When compared between groups after the intervention, the levels in the observation group were lower than those in the control group (P<0.05). The levels of activated partial thromboplastin time (APTT), prothrombin time (PT), and quality of life score were compared within the group before and after the intervention, showing an increasing trend. When compared between groups after the intervention, the observation group was higher than the control group (P<0.05). The occurrence rate for deep vein thrombosis of the lower extremities in the control group was higher than that in control group (P<0.05). The overall satisfaction of patients in the control group was lower than that in the observation group (P<0.05). Conclusion: For patients undergoing thoracic surgery, the combined intervention of cluster nursing and pneumatic therapy can effectively improve the blood flow in the lower extremities of patients, enhance their coagulation function, promote the improvement of their quality of life, and reduce the incidence of deep vein thrombosis in the lower extremities. Patients have a high satisfaction with this nursing intervention model.
  • Modern nursing
    The Impact of Empowerment Emotional Intervention Combined with Transtheoretical Model Intervention on Negative Emotions and Epileptic Seizures in Adult Epilepsy Patients
    LIN Huiyan, CHEN Meiyan.
    2025, 23(26): 99-102. https://doi.org/10.14033/j.cnki.cfmr.2025.026.027
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: To explore the application value of empowerment emotional intervention combined with transtheoretical model (TTM) intervention in adult epilepsy patients. Method: A total of 92 adult epilepsy patients admitted to the First Affiliated Hospital of Xiamen University from January 2022 to December 2023 were selected as the research subjects and divided into the observation group and the combined group according to different nursing methods, with 46 cases in each group. The control group received routine care, while the observation group received empowerment emotional intervention combined with TTM intervention. The comparisons were performed on negative emotions, self-management ability, seizure rate, and quality of life in both groups. Result: Compared with the control group, the observation group had lower incidence of negative emotions and epilepsy, and higher scores of self-management ability and quality of life after intervention (P<0.05). Conclusion: Empowerment emotional intervention combined with TTM intervention can alleviate negative emotions in adult epilepsy patients, enhance self-management ability, reduce epileptic seizures, and thereby improving the quality of life.
  • Modern nursing
    The Effect of Child Friendly Intervention Combined with Accelerated Rehabilitation Surgery Nursing on Adverse Emotions and Postoperative Recovery in Children Undergoing Thoracoscopic Segmentectomy
    WU Shunying, WENG Yanlian.
    2025, 23(26): 103-106. https://doi.org/10.14033/j.cnki.cfmr.2025.026.028
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: To explore the influence of childlike fun intervention combined with enhanced recovery after surgery nursing on the negative emotions and postoperative recovery of children undergoing thoracoscopic pulmonary segmentectomy. Method: A total of 116 children who underwent thoracoscopic segmental lung resection and were admitted to the First Affiliated Hospital of Xiamen University from January 2020 to October 2024 were selected as the research subjects. They were divided into two groups according to different intervention methods, with 35 cases in each group. The control group received conventional thoracoscopic segmental lung resection care, while the observation group received childlike intervention combined with enhanced recovery after surgery care. The negative emotions, postoperative recovery status, compliance with medical advice and complications of the two groups were compared. Result: The Screen for Child Anxiety Related Emotional Disorders (SCARED) and the Pediatric Medical Fear Scale (CMFS) in the observation group were lower than the control group, the differences were statistically significant (P<0.05). The indwelling time of the drainage tube and the hospital stay in the observation group were shorter than the control group, the differences were statistically significant (P<0.05). The Visual Analogue Scale (VAS) score 72 hours after surgery was lower than that in the control group. The compliance with medical advice in the observation group was better than that in the control group, and the incidence of complications was lower. The differences were statistically significant (P<0.05). Conclusion: Child-friendly intervention combined with enhanced recovery after surgery nursing can relieve the negative emotions of children undergoing thoracoscopic pulmonary segmentectomy, improve compliance with medical advice, accelerate postoperative recovery speed, and reduce the risk of complications.
  • Modern nursing
    Application of Palliative Care Combined with Ankle Pump Exercise in Bedridden Patients with Advanced Cancer
    LUO Xiaoling.
    2025, 23(26): 106-110. https://doi.org/10.14033/j.cnki.cfmr.2025.026.029
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: To explore the application effect of palliative care combined with ankle pump exercise in patients in bed with advanced tumors. Method: 60 patients with advanced bedridden tumors who were hospitalized at Kunshan Mental Health Center from January 2023 to December 2024 were selected as the research subjects and divided into the observation group (n=30) and the control group (n=30) according to the random number table method. The control group was given routine care, while the observation group was given palliative care combined with ankle pump exercise on this basis. The fatigue degree, negative emotions, attitudes towards death, pain scores, incidence of deep vein thrombosis, quality of life and other indicators of the two groups were compared. Result: After the intervention, compared with the control group, the observation group exhibited significantly lower scores for pain, negative affect, fatigue severity, and across all dimensions of attitudes toward death, higher quality-of-life scores, and a lower incidence of deep vein thrombosis. The differences were statistically significant (P<0.05). Conclusion: Palliative care combined with ankle pump exercise has a significant effect in improving the physical and psychological symptoms of advanced bedridden tumor patients, reducing the incidence of deep vein thrombosis in patients and improving their quality of life.
  • Modern nursing
    Application of Optimization of Transitional Nursing Process and Health Education Process in EICU under Multidisciplinary Collaboration Model in Severe Pancreatitis
    CHEN Yaxiu, L Mingfang.
    2025, 23(26): 111-114. https://doi.org/10.14033/j.cnki.cfmr.2025.026.030
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: To explore the application effect of the transitional nursing process and health education process optimization in the emergency intensive care unit (EICU) under the multidisciplinary collaboration model in severe pancreatitis. Method: A total of 100 patients admitted to the First Affiliated Hospital of Xiamen University from January to December 2024 were selected and divided into the control (n=53) and observation group (n=47). The control group implemented the conventional transitional nursing process, while the observation group implemented the transitional nursing process under the multidisciplinary collaboration model. The hospitalization time, ICU return rate, patients' health behavior ability and family care ability of the two groups were compared. The occurrence of risk events and the satisfaction of patients' families during the nursing period were recorded. Result: Compared with the control group, the observation group had shorter hospital stay (P<0.05).After the intervention, the observation group got a higher score for the Self-Rated Abilities for Health Practices (SRAHP) scale and a lower score for the Family Caregiver Task Inventory (FCTI) compared with the control group (P<0.05). The incidence of risk events during the intervention was comparable between the two groups (P>0.05). The observation group got a higher score for the Chinese version of Critical Care Family Satisfaction Survey (C-CCFSS) compared with the control group (P<0.05). Conclusion: The optimization of the transitional nursing process and health education process in the EICU based on the multidisciplinary collaboration model can shorten the hospital stay of patients with severe pancreatitis. While improving the health behavior ability of patients, it can also enhance the care ability and satisfaction of caregivers.
  • Modern nursing
    Application of Universalized Standardized Cancer Pain in the Care of Cervical Cancer Patients
    HAN Lili, PANG Qingqun, ZHU Naijin.
    2025, 23(26): 114-117. https://doi.org/10.14033/j.cnki.cfmr.2025.026.031
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: To evaluate the effectiveness of universalized standardized cancer pain management in cervical cancer patient care. Method: A total of 100 cervical cancer patients admitted to the First Affiliated Hospital of Bengbu Medical University were selected as the study objects and randomly assigned into two groups from January 2023 to December 2024. The control group (n=50) received standard care, while the intervention group (n=50) implemented universalized standardized cancer pain management. The pain intensity, sleep quality, coping strategies, negative emotions, and nursing satisfaction were compared between the two groups. Result: The scores of pain and sleep quality in the study group were lower than those in the conventional group after the intervention. The confrontation scores of study group were higher than those of the intervention group, the submission and avoidance scores were lower than that of the intervention group conventional group. The scores of the Self-Rating Anxiety Scale (SAS) and the Self-Rating Depression Scale (SDS) in the study group were lower than those in the conventional group after the intervention (P<0.05). The discharge satisfaction of the research group was higher than that of the conventional group (P<0.05). Conclusion: Implementing universalized standardized cancer pain management in cervical cancer patients can effectively alleviate pain, reduce anxiety, improve sleep quality, and enhance nursing outcomes, demonstrating significant practical value.
  • Modern nursing
    Study on the Comprehensive Effect of Multidimensional Psychological Support Intervention Intervention on Relieving Psychological Stress and Improving Quality of Life of Patients with Differentiated Thyroid Carcinoma Treated with Iodine 131
    ZHENG Xiuhua, LIANG Liping, CHEN Kang, LIN Tao, CHANG Kaimin, YANG Zida.
    2025, 23(26): 118-121. https://doi.org/10.14033/j.cnki.cfmr.2025.026.032
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: To explore the influence of multidimensional psychological support intervention on psychological stress and quality of life of postoperative patients with differentiated thyroid carcinoma during iodine 131 treatment. Method: 227 patients with differentiated thyroid carcinoma admitted to the nuclear medicine department of the 910th Hospital of the Joint Logistics Support Force of the Chinese People's Liberation Army (January 2019 to December 2023) were selected as the research object, and were divided into control group (n=113, routine nursing measures) and observation group (n=114, routine nursing measures combined with multidimensional psychological support intervention). Symptom CheckList-90 (SCL-90), Mishel Uncertainty in Illness Scale (MUIS), Medical Coping Modes Questionnaire (MCMQ) and Short Form Health Survey (SF-36) were used to evaluate the psychological stress response, disease uncertainty, coping style and quality of life of the two groups, and the differences of the above indexes were compared. Result: After the intervention, the scores of SCL-90, MUIS, avoidance and yield in both groups decreased, while the scores of face and SF-36 increased (P<0.05). After the intervention, the above indexes in the observation group were better than those in the control group (P<0.05). Conclusion: Multidimensional psychological support intervention can alleviate the psychological stress and uncertainty of disease in patients with differentiated thyroid carcinoma treated with iodine 131 after operation, improve their coping style and improve their quality of life.
  • Modern nursing
    Effect of King's Theory of Reaching the Standard Combined with Cluster Intervention Model on Tracheotomy in Stroke Patients
    LI Chen.
    2025, 23(26): 122-125. https://doi.org/10.14033/j.cnki.cfmr.2025.026.033
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: To explore the effect of applying King's achievement theory combined with the cluster intervention model in patients with stroke undergoing tracheotomy. Method: A total of 90 stroke patients with tracheotomy admitted to the First Affiliated Hospital of Bengbu Medical University from June 2023 to July 2024 were selected as the research subjects. They were divided into a control group and an observation group by the coin-tossing method, with 45 cases in each group. The control group was given conventional nursing intervention, while the observation group added the King's achievement theory combined with the cluster intervention mode on the basis of the control group for 3 months. The satisfaction with nursing, anxiety and depression, blood gas indicators and quality of life levels after treatment were compared between the two groups. Result: After the intervention, the nursing satisfaction of the control group (80.00%) was lower than that of the observation group (95.56%) (P<0.05). After the intervention, the scores of the Hamilton Anxiety Scale (HAMA) and the Beck Depression Questionnaire (BDI) in both groups decreased, and the observation group was lower, with statistically significant differences (P<0.05). The blood oxygen saturation (SatO2) and partial pressure of oxygen (PaO2) in both groups increased,the observation group is higher (P<0.05). The partial pressure of carbon dioxide (PCO2) in both groups decreased, the observation group was lower (P<0.05). After the intervention, the scores of each sub-item of the quality of life summary in both groups increased, the observation group is higher (P<0.05). Conclusion: The application of King's achievement theory combined with the cluster intervention model in patients with tracheotomy after stroke can effectively improve nursing satisfaction, alleviate anxiety and depression, and improve blood gas index levels and quality of life.
    • Experience
  • Experience
    Study on the Application of Self-Made Chinese Herbal Heat Packs in Mechanical Phlebitis after PICC Catheterization in Tumor Patients
    XIAN Yuelian, ZHONG Fanxiang, MO Suying, LIN Xiaofang, FAN Huijie, ZHANG Wei.
    2025, 23(26): 126-130. https://doi.org/10.14033/j.cnki.cfmr.2025.026.034
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: To explore the application effect of self-made Chinese herbal heat packs in mechanical phlebitis after percutaneously inserted centeral catheter (PICC) in cancer patients. Method: A total of 76 patients who underwent PICC replacement at Yangjiang People's Hospital from June 2023 to November 2024 were selected as the subjects and randomly divided into two groups by the envelope method, with 38 cases in each group. The control group was given routine care to help patients change dressings regularly, once a week. The observation group was combined with self-made traditional Chinese medicine hot compress packs for intervention. Both groups were continuously intervened for 7 days. The incidence of mechanical phlebitis, the degree of swelling, the degree of pain, the bleeding at the PICC puncture site, the quality of life and the incidence of complications were compared between the two groups. Result: The incidence of mechanical phlebitis in the observation group was lower than that in the control group, and the difference was statistically significant (P<0.05). After the intervention, the swelling and pain were relieved in both groups, and the bleeding area at the PICC puncture site was reduced. The scores of swelling and pain and the bleeding area at the PICC puncture site in the observation group were lower than those in the control group, and the difference was statistically significant (P<0.05). After interventien, the quality of life of the observation group was higher than that of the control group. The incidence of complications was lower than that of the control group, and the difference was statistically significant (P<0.05). Conclusion: The self-made traditional Chinese medicine hot compress bag has a good effect in the postoperative PICC surgery of tumor patients. It can reduce the incidence of mechanical phlebitis after surgery, help alleviate the degree of swelling and pain, reduce the bleeding and complication rate at the PICC puncture site, and improve the quality of life of patients.
  • Experience
    The Effect of Acupuncture Synchronized Rehabilitation Exercise on Upper Limb Motor and Sensory Function after Stroke
    SHEN Yanling, SU Ting, CHEN Yinqian.
    2025, 23(26): 130-133. https://doi.org/10.14033/j.cnki.cfmr.2025.026.035
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: To explore the effect of acupuncture and concurrent rehabilitation exercise on the motor and sensory functions of the upper limbs after stroke. Method: A total of 100 patients in the recovery period of stroke admitted to Longyan Hospital of Traditional Chinese Medicine from February 2023 to October 2024 were selected as the study objects and divided into Group A (50 cases) and Group B (50 cases) by random number table method. Group A received conventional rehabilitation exercises, while Group B received acupuncture on the basis of Group A. The Fugl-Meyer Assessment (FMA) score, Barthel Index (BI) score, sensory function score, Stroke-specific Quality of Life Scale (SS-QOL) score, and patient nursing satisfaction of group A and group B were compared before and after the intervention. Result: Following a 4-week intervention, the Berg Balance Index (BI) and upper limb Fugl-Meyer Assessment (FMA) scores in Group B were significantly higher than those in Group A, with statistically significant differences (P<0.05). Similarly, the scores for light touch sensation and acupuncture response in Group B were significantly higher than those in Group A (P<0.05). Furthermore, the scores for activity ability, self-care, and upper limb function were also significantly improved in Group B compared to Group A (P<0.05). The nursing satisfaction rate in Group B was 92.00%, which was notably higher than that in Group A (78.00%), and this difference was statistically significant (P<0.05). Conclusion: The application of acupuncture synchronous rehabilitation exercise in stroke patients can promote the recovery of motor and sensory functions of the affected upper limb, improve the quality of life of patients, and the patients' satisfaction with nursing is relatively high.
  • Experience
    Comparative Study on the Effects of SIMV+VG and PSV+VG Ventilation Modes on Important Indicators and Inflammatory Mediators in Newborns
    WANG Xiaowei, WANG Xinping.
    2025, 23(26): 134-137. https://doi.org/10.14033/j.cnki.cfmr.2025.026.036
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: To analyze the effects of two ventilation modes, namely synchronous intermittent mandatory ventilation (SIMV) + volume guarantee (VG) and pressure support ventilation (PSV) +VG, on the clinical indicators and inflammatory mediators of neonatal respiratory failure (NRF). Method: A total of 100 children with NRF admitted to Qingyang Maternal and Child Health Hospital from January 2023 to December 2024 were selected as the research subjects and randomly divided into a control group and a study group, with 50 cases in each group. The control group used the SIMV+VG mode, while the study group used the PSV+VG mode. The levels of arterial partial pressure of oxygen (PaO2), arterial partial pressure of carbon dioxide (PaCO2), oxygenation index (OI), respiratory index (RI), inflammatory mediators [C-reactive protein (CRP), procalcitonin (PCT), and neutrophil percentage (NEUT %)], and ventilation indicators [mechanical ventilation time, weaning duration and extubation failure rate] and complications were compared between the two groups before and after treatment. Result: There were statistically significant differences in PaO2, PaCO2, OI and RI between the two groups after treatment (P<0.05). After treatment, the levels of CRP, PCT and NEUT % in the study group were lower than those in the control group, the weaning duration in the study group was shorter than that in the control group, and the extubation failure rate in the study group was lower than that in the control group. The differences were statistically significant (P<0.05). There was no statistically significant difference in the mechanical ventilation time and the total incidence of complications between the two groups (P>0.05). Conclusion: Compared with the SIMV+VG mode, the PSV+VG mode intervention for children with NRF can effectively improve oxygenation indicators, down-regulate the levels of inflammatory mediators, shorten the weaning time, reduce the risk of weaning failure, and does not increase the risk of complications. It is safe and feasible.
  • Experience
    Influence of Cholecystectomy Timing after PTGD on Surgical Effect and Complications in Elderly Patients with Acute Cholecystitis
    ZHANG Chu, CUI Yunwei.
    2025, 23(26): 137-140. https://doi.org/10.14033/j.cnki.cfmr.2025.026.037
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: To investigate the influence of laparoscopic cholecystectomy (LC) at different timing after percutaneous transhepatic gallbladder drainage (PTGD) on surgical effect and complications in elderly patients with acute cholecystitis (AC). Method: Elderly patients with AC who received PTGD followed by LC in the Second Affiliated Hospital of Bengbu Medical University were selected from October 2022 to October 2024. According to the time from PTGD to LC, the patients were divided into early group (LC at 1 to 4 weeks after PTGD) and delayed group (LC at 4 to 8 weeks after PTGD). The propensity matching score was used to exclude the influence of baseline data confounding factors. Finally, 49 patients with comparable baseline data were identified in each group. The LC-related indexes (surgical time, intraoperative blood loss, postoperative first ambulation time, total length of hospital stay) and inflammatory indexes [white blood cell count (WBC), C-reactive protein (CRP), procalcitonin (PCT)] before PTGD and after LC were compared between the two groups, and the incidence rates of postoperative complications were counted. Result: The blood loss during LC in delayed group was less than that in early group, and the postoperative ambulation time and total length of hospital stay were shorter, with statistical differences (P<0.05). No statistical significance was found in LC time between the two groups (P>0.05). After LC, the levels of WBC, CRP and PCT in the two groups were reduced compared with those before PTGD, and the levels in delayed group were lower compared to early group, with statistical differences (P<0.05). The total incidence rate of postoperative complications was 6.12% in delayed group and that in early group was 14.29%, with no statistical difference (P>0.05). Conclusion: For elderly patients with AC, compared with early surgery (1 to 4 weeks), delayed LC (4 to 8 weeks) after PTGD can more effectively reduce intraoperative blood loss, accelerate postoperative recovery, and relieve systemic inflammatory response, and it does not increase the risk of complications.
  • Experience
    Observation on the Therapeutic Effect and Facial Muscle Function of the Combination of Method Penetrating Along Meridians Method and Qufeng Jiedu Huoluo Decoction in the Treatment of Acute Peripheral Facial Paralysis
    LU Xixia.
    2025, 23(26): 141-145. https://doi.org/10.14033/j.cnki.cfmr.2025.026.038
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: To explore the therapeutic effect of the penetrating along meridians method combined with Qufeng Jiedu Huoluo Decoction in the treatment of acute peripheral facial paralysis. Method: A total of 80 acute peripheral facial paralysis patients were admitted to Renhuai People's Hospital between June 2022 and December 2024. According to the random envelope method, the patients were divided into the control group (n=40 cases, treated with conventional Western medicine combined with Qufeng Jiedu Huoluo Decoction) and the combined group (n=40 cases, treated with meridian puncture method on the basis of the control group). The therapeutic effects, TCM syndrome scores, facial nerve functions [House-Brackmann Facial Nerve Function Grading Scale (H-B), facial paralysis score Portmann], facial neuromuscular electromyography and adverse reactions were compared between the two groups. Result: Compared to the control group, the combined group demonstrated a significantly higher total effective rate (P<0.05). After 4 weeks of treatment, the combined group showed lower TCM syndrome scores,House-Brackmann (H-B) scores but higher Portmann scores compared to the control group (P<0.05). Additionally, the combined group exhibited lower compound muscle action potential (CMAP) amplitudes and blink reflex (BR) latencies than the control group (P<0.05). There was no statistically significant difference in the total incidence of adverse reactions between the two groups (P>0.05). Conclusion: The meridian penetration method combined with Qufeng Jiedu Huoluo Decoction has a significant effect in the treatment of acute peripheral facial paralysis. It can improve clinical symptoms, the functional level of the facial nerve, reduce facial nerve damage, and has good safety.
  • Experience
    Clinical Study of Finerenone Combined with Traditional Chinese Medicine Enema for Detoxification, Purging and Removing Blood Stasis on Diabetic Kidney Disease Nephropathy
    GONG Qiong, WANG Haiyan.
    2025, 23(26): 145-148. https://doi.org/10.14033/j.cnki.cfmr.2025.026.039
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: To explore the clinical effect of finerenone combined with traditional Chinese medicine enema for detoxification, purging, and removing blood stasis in the treatment of diabetic kidney disease (DKD), and to offer new therapeutic directions for the clinic. Method: 60 patients with DKD admitted to the Traditional Chinese Medicine Hospital of Qianxinan Prefecture from December 2023 to December 2024 were taken as the objects. All selected cases were randomly assigned to two groups (observation group and control group). Both groups received conventional basic treatments such as lowering blood glucose, blood lipid, blood pressure and improving circulation. On this basis, the control group was treated with oral fineridone, while the observation group was treated with traditional Chinese medicine enema for detoxification, purging and removing blood stasis. The clinical efficacy and various experimental indicators of the two groups were compared. Result: Compared with the control group, the observation group had higher clinical efficacy and traditional Chinese medicine syndrome efficacy (P<0.05). The comparisons on fasting blood glucose, urine albumin-to-creatinine ratio (UACR), blood urea nitrogen (BUN), and blood creatinine (Scr) in both groups before treatment expressed no statistical difference (P>0.05). The observation group had lower indicators than the control group after treatment (P<0.05). The adverse reactions of both groups were compared, which showed no difference (P>0.05). Conclusion: Finerenone and traditional Chinese medicine enema for detoxification, purging, and removing blood stasis can enhance the clinical efficacy of patients with DKD, lower blood glucose levels, improve renal function, and reduce UACR. It has complementary advantages and cumulative therapeutic effects, and is safe and reliable.
  • Experience
    The Effect of Cangerzi San Combined with Yupingfeng San Modified in the Treatment of Allergic Rhinitis with Lung Qi Deficiency
    ZHANG Huaxing, CHEN Qin.
    2025, 23(26): 149-153. https://doi.org/10.14033/j.cnki.cfmr.2025.026.040
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: To observe the effect of Xanthium sibiricum powder combined with modified Yupingfeng powder and triamcinolone acetonide nasal spray in the treatment of Weibiao Bugu Type Rhinitis with lung qi deficiency and coldness and unstable exterior defense. Method: A total of 80 patients with Weibiao Bugu Type Rhinitis of lung qi deficiency, cold and weak exterior defense type admitted to the outpatient department of outpatient service of Sanming Hospital of Integrated Traditional Chinese and Western Medicine affiliated to Fujian University of traditional Chinese Medicine from February to October 2024 were selected and randomly divided into the experimental group (Cangerzi San combined with Yupingfeng San modified + triamcinolone acetonide Nasal spray, group A) and the control group (triamcinolone acetonide nasal spray, group B), with 40 cases in each group. The treatment course for both groups was one month. Group A completed the study with 34 cases, and Group B completed the study with 38 cases. Nasal Symptom Score (TNSS), Nasal Conjunctivitis Quality of Life Questionnaire (RQLQ), and TCM Syndrome Score were used to record the scores of patients when they evaluated themselves in the past 6 months and at the end of the treatment course.Blood samples were drawn to detect interleukin-10 (IL-10) and CD4+CD25+Foxp3+ regulatory T cells (T cells, CD4+CD25+Foxp3+Treg) before and one month after the treatment of the patients. Result: Compared within the same group of indicators, TNSS, RQLQ, and TCM syndrome score all decreased after treatment, while IL-10 and CD4+CD25+Foxp3+Treg increased after treatment, and the differences were statistically significant (P<0.05). After treatment, when comparing the same indicators between groups, the RQLQ and TCM syndrome score in group A were lower than those in group B. The IL-10 and CD4+CD25+Foxp3+Treg in group A were higher than those in group B, and the differences were statistically significant (P<0.05). The effective rate was 91.18% in group A and 71.05% in group B, and the difference was statistically significant (P<0.05). Conclusion: The combination of Cangerzi San and modified Yupingfeng San with triamcinolone acetonide nasal spray is superior to the use of nasal spray alone in improving the clinical symptoms of AR patients with lung qi deficiency and coldness and unstable exterior defense. Both treatment plans are effective.
  • Experience
    Clinical Observation of Early Laparoscopic Cholecystectomy within 48 h for Patients with Gallstone Pancreatitis
    LUO Wen, FANG Weilin, GAO Linjie.
    2025, 23(26): 153-156. https://doi.org/10.14033/j.cnki.cfmr.2025.026.041
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: To explore the clinical effect of early laparoscopic cholecystectomy (LC) within 48 hours in the treatment of patients with gallstone pancreatitis (GSP). Method: A total of 80 patients with GSP admitted to Guangze County Hospital from January 2023 to October 2024 were selected as the research subjects. They were divided into the early group and the delayed group by stratified random grouping method, with 40 cases in each group. The early group received LC within 48 hours after the onset of the disease, while the delayed group received LC beyond 48 hours after the onset of the disease. The surgery-related indicators, postoperative recovery-related indicators, biochemical indicators on postoperative day 1, day 3 and day 7, and the occurrence of complications were compared between the two groups. Result: Compared with the delayed group, the early group showed reductions in operation time, intraoperative blood loss, hospital stay, postoperative recovery time of bowel sounds, time of postoperative first exhaust, drainage time, and total drainage volume (P<0.05). Compared with the levels on postoperative day 1, the levels of alanine aminotransferase + aspartate aminotransferase (ALT+AST) and alkaline phosphatase (AKP) in both groups were higher on postoperative day 3 (P<0.05). Moreover, the levels of ALT + AST and AKP were lower on postoperative day 7 than on postoperative day 1 and day 3 (P<0.05). There was no significant difference in the levels of ALT + AST and AKP between the groups (P>0.05). There were no significent differences in complication rates between the two group (P>0.05). Conclusion: Early LC within 48 hours for patients with GSP shows significant advantages in surgery-related indicators and postoperative recovery, without increase in abnormal postoperative biochemical indicators. However, its impact on complications remains to be explored.
    • Synthetic medicine
  • Synthetic medicine
    Clinical Efficacy and Safety Evaluation of the Combination of Traditional Chinese Medicine Acupuncture and Western Medicine in Patients with Knee Arthritis
    HUANG Yu, DU Shengyang.
    2025, 23(26): 157-161. https://doi.org/10.14033/j.cnki.cfmr.2025.026.042
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: To explore and evaluate the clinical efficacy and safety of combining traditional Chinese medicine acupuncture with Western medicine in the treatment of knee osteoarthritis. Method: A total of 100 patients with knee osteoarthritis who visited the Rehabilitation Department of Shifang Second Hospital from May 2022 to May 2023 were selected as the study sample. They were randomly divided into a control group and an observation group, with 50 cases in each group. The control group received conventional Western medical treatment, while the observation group received acupuncture intervention in addition to this treatment. After a continuous treatment period of 4 weeks, a comparative analysis was conducted on the pain levels, knee joint function, and the occurrence of adverse reactions between the two groups. Result: At the second week of treatment, at the end of treatment (4th week), and during the follow-up phase (8th week), pain scores in both groups significantly decreased compared to before treatment, while knee joint function scores notably improved. The improvement in the observation group was superior to the control group, with statistically significant differences (P<0.05). Additionally, the observation group had significantly higher scores than the control group in terms of physiological function, bodily pain, social activity ability, overall health, and mental health (P<0.05). The total effective treatment rate was also significantly higher in the observation group compared to the control group (P<0.05). Regarding the incidence of adverse reactions, no significant difference was observed between the two groups (P>0.05). Conclusion: The combined treatment of traditional Chinese medicine acupuncture and Western medicine for knee osteoarthritis shows significant clinical efficacy, especially in pain reduction and functional improvement, with good safety. It can provide an effective treatment option for clinical practice.
  • Synthetic medicine
    Application of Supraclavicular Approach in Unilateral Neck Lymph Node Dissection
    XUE Chun, YUE Xicheng, YAO Tingjing, QIAN Liyu, TANG Jie, JIANG Fangqian, JIN Gongsheng.
    2025, 23(26): 161-164. https://doi.org/10.14033/j.cnki.cfmr.2025.026.043
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: To explore the application effect of the lateral cervical approach of the supraclavicular fossa in unilateral cervical lymph node dissection. Method: A total of 56 patients who underwent unilateral thyroid surgery and cervical lymph node dissection in the First Affiliated Hospital of Bengbu Medical University from July 2020 to July 2024 were selected as the research subjects. The patients were divided into the lateral cervical approach group (n=28 The approach was made through and oblique incision in the supraclavicular fossa) and median incision group (n=28 Enter the route through the cut of the neck whire line) according to the surgical approach. The postoperative complications, surgery-related indicators, pain scores and cosmetic effects of the two groups were compared. Result: The occurrence of postoperative complications (such as hoarseness, choking cough when drinking water and hypocalcemia) in the lateral cervical approach group was better than that in the median incision group, and the difference was statistically significant (P<0.05). The surgery-related indicators, pain scores and cosmetic effects of the lateral cervical approach group were all better than those of the median incision group, and the difference was statistically significant (P<0.05). Conclusion: Compared with the traditional median incision for lateral cervical lymph node dissection, lateral cervical lymph node dissection through the lateral cervical approach incision can reduce postoperative complications for patients, lower the values of surgery-related indicators, alleviate patient pain, and achieve higher cosmetic satisfaction than traditional surgical methods.
  • Synthetic medicine
    Effect of Guwei Jianpi Formula Combined with Nasal Massage on Allergic Rhinitis in Children with Lung-Qi Deficiency
    XIE Chundi, LAI Shengxiu.
    2025, 23(26): 165-168. https://doi.org/10.14033/j.cnki.cfmr.2025.026.044
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: To explore the effect of the Guwei Jianpi Formula combined with nasal massage in the treatment of allergic rhinitis (AR) in children with lung-qi deficiency type. Method: A total of 70 children with AR admitted to Longyan Hospital of Traditional Chinese Medicine from September 2022 to September 2023 were included in the study and randomly divided into the combined group (n=35) and the control group (n=35). The control group was given conventional Western medical treatment, while the combined group was treated with the Guwei Jianpi Formula and nasal massage on this basis. The therapeutic effects, adverse reactions, clinical symptom and sign scores before and after treatment, serum immunoglobulin E (IgE), and eosinophil (EOS) levels of the two groups were compared. Result: The total effective rate of the combined group was higher than that of the control group (P<0.05). After treatment, the vital sign score, clinical symptoms, serum IgE and EOS levels in the combined group were lower than those in the control group (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion: The combination of Guwei Jianpi Formula and nasal massage in the treatment of AR children with lung-qi deficiency type can reduce the levels of serum IgE and EOS, improve clinical symptoms and signs, has a significant therapeutic effect, and is highly safe.
  • Synthetic medicine
    The Impact of Combining Traditional Chinese Medicine Fumigation with LF-rTMS on Upper Limb Motor Function during the Convalescent Period of Cerebral Infarction in Patients with Qi Deficiency and Blood Stasis
    CHEN Bifang, HUANG Ping, HUANG Yanghua.
    2025, 23(26): 168-171. https://doi.org/10.14033/j.cnki.cfmr.2025.026.045
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: To investigate the synergistic effects of Buyang Huanwu Decoction fumigation therapy and Low Frequency Repetitive Transcranial Magnetic Stimulation (LF-rTMS) on upper extremity motor recovery in cerebral infarction patients with qi deficiency and blood stasis during the convalescent phase. Method: 70 convalescent-phase stroke patients with qi-blood stasis pattern and upper extremity motor impairment from Ningde TCM Hospital were taken in the study. Using computer-generated randomization, participants were equally allocated to the control group and observation groups (with 35 cases in each group). The control group was treated with low-frequency repetitive transcranial magnetic stimulation, while the observation group was treated with Buyang Huanwu Decoction traditional Chinese medicine fumigation and washing on the basis of the control group. The Fugl-Meyer Assessment (FMA-UE) score of the upper limb and the modified Barthel index (MBI) score of the two groups before and after treatment were compared. Result: Both groups demonstrated statistically significant improvements in FMA-UE and MBI scores post-intervention compared to baseline (P<0.05). Moreover, The intervention group showed superior FMA-UE scores and MBI scores compared to controls, with statistically significant between-group differences (P<0.05).Conclusion: The combined therapy of Buyang Huanwu Decoction herbal fumigation and low-frequency rTMS demonstrated superior efficacy in enhancing upper limb motor function and activities of daily living (ADL) in post-stroke patients with qi-blood stasis syndrome.
    • Review
  • Review
    Research Progress on the Combined Treatment of Traditional Chinese and Western Medicine for Meniscus Injury
    LI Meijiao, JIANG Min.
    2025, 23(26): 172-175. https://doi.org/10.14033/j.cnki.cfmr.2025.026.046
    Abstract ( ) PDF ( ) Knowledge map Save
    Meniscus injury is a common knee joint disease. As a common sports injury, it often leads to symptoms such as knee joint pain and limited movement, seriously affecting patients' daily life and athletic ability. This literature reviews the latest research progress in the treatment of meniscus injury with both traditional Chinese and Western medicine. The exploration of treatment methods has always been a hot topic in the field of orthopedics. In recent years, significant progress has been made in the clinical application of integrated traditional Chinese and Western medicine in the treatment of meniscus injuries. This article explores the advantages and clinical application prospects of different treatment methods, aiming to provide references for clinical treatment.
  • Review
    Research Progress on Adverse Pregnancy Outcomes with Premature Rupture of Membranes and Chorioamnionitis
    HOU Lu, FU Dan.
    2025, 23(26): 176-180. https://doi.org/10.14033/j.cnki.cfmr.2025.026.047
    Abstract ( ) PDF ( ) Knowledge map Save
    Premature rupture of membranes (PROM) is a common complication during pregnancy, and one of the main risks associated with it is chorioamnionitis (CA). PROM combined with CA can cause fetal inflammatory response syndrome, increase the incidence of neonatal infectious diseases and perinatal complications, and in severe cases, it can endanger the lives of both the mother and the child. Understanding its pathogenesis, grasping adverse pregnancy outcomes, early prediction and identification of CA based on biomarkers from existing research, and strengthening prenatal management will help reduce the incidence of maternal and neonatal complications.
  • Review
    Progress in the Diagnosis and Treatment of Hemophilia Factor Lyase and Thrombotic Microvascular Disease
    YAN Ni, BAI Jun, XU Zekun.
    2025, 23(26): 181-184. https://doi.org/10.14033/j.cnki.cfmr.2025.026.048
    Abstract ( ) PDF ( ) Knowledge map Save
    Thrombotic microangiopathy (TMA) is a group of diseases characterized by microvascular embolism. Its etiology and pathogenesis are complex and diverse, including primary thrombotic microangiopathy and secondary thrombotic microangiopathy. There is a close correlation between A Disintegrin and Metalloproteinase with Thrombospondin Type 1 motif, member 13 (ADAMTS13) and TMA. There are various methods for detecting its activity, and it has positive clinical significance in disease diagnosis, prognosis assessment, and disease differentiation. The role of ADAMTS13 in the diagnosis and treatment of thrombotic thrombocytopenic purpura is relatively clear, and it may also play an important role in other types of thrombotic microvascular diseases. The determination of its activity helps to distinguish different types of hemolytic uremic syndrome and other diseases, and provides a basis for treatment. The activity of ADAMTS13 has been reduced to varying degrees in thrombotic microvascular diseases such as disseminated intravascular coagulation, systemic lupus erythematosus nephritis, and severe liver injury, and it may serve as an auxiliary diagnostic indicator for such diseases.

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