2025 Volume 23 Issue 19 Published: 05 July 2025
  

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  • Article
    Analysis of the Effect of the Application of Pressure Tourniquets Throughout and Halfway of Total Knee Arthroplasty
    Lü Xiaoyan, HU Jianbin
    2025, 23(19): 1-4. https://doi.org/10.14033/j.cnki.cfmr.2025.19.001
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    Objective: To investigate the effect of using pressure tourniquets throughout and halfway of total knee arthroplasty. Method: 120 patients with knee osteoarthritis (KOA) in the hospital from March 2022 to March 2024 were selected and randomly divided into two groups using a random number table: Group A and Group B, with 60 patients in each group. In total knee replacement surgery, Group A was given a full tourniquet, while Group B was given a half tourniquet. The intraoperative blood loss, surgical time, postoperative pain [Visual Analog Scale (VAS)], degree of swelling, quadriceps muscle strength [Manual Muscle Strength Test (MMT) score], and knee joint function [Hospital for Special Surgery Knee Score (HSS)] between two groups were compared. Result: The intraoperative blood output of patients in group B was higher than that in group A, and the operation time in group B was longer than that in group A (P<0.05). 1 d and 3 d after operation, VAS scores in group B were lower than those in group A (P<0.05). 1 d and 3 d after operation, the degree of limb swelling in group B was lower than that in group A (P<0.05). 7 d and 14 d after operation, the MMT scores of patients in group B were higher than those in the control group (P<0.05). 7 d and 14 d after operation, the HSS score in group B was higher than that in group A (P<0.05). Conclusion: The use of a half tourniquet in total knee arthroplasty can alleviate early postoperative pain and limb swelling in patients, promote the recovery of quadriceps muscle strength, and improve knee joint function. However, using a half tourniquet during surgery can prolong the patient's surgery time and increase intraoperative bleeding.
  • Article
    Application Value of Laparoscopic Gallstones Surgery in the Patients with Gallstones
    CHEN Hai
    2025, 23(19): 4-7. https://doi.org/10.14033/j.cnki.cfmr.2025.19.002
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    Objective: To investigate the application value of laparoscopic gallstones surgery in the patients with gallstones. Method: 90 patients with gallstones surgery from January 2023 to March 2024 were divided into control group (n=45) and observation group (n=45) according to the method of random number table. The control group were treated with small incision surgery, and the observation group were treated with laparoscopic gallstones surgery. Then the operation time, blood loss, hospitalization time, complication rates, cholecystokinin(CCK) and its receptor, inflammatory mediators [cytokines interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), interleukin-8 (IL-8) and other inflammatory mediators prostaglandin E2 (PGE2) and platelet-activating factor (PAF)] before and after the surgery of two groups were compared. Result: The operation time of two groups were compared, and the difference was not statistically significant (P>0.05), and the hospitalization time of observation group was significantly shorter than that of control group, the blood loss was significantly less than that of control group, the total complication rate was significantly lower than that of control group, and the differences were statistically significant (P<0.05). The CCK and its receptor, cytokines and other inflammatory mediators of two groups before the surgery were compared, and the differences were not statistically significant (P>0.05). The CCK and its receptor of observation group 1 d and 3 d after the surgery were significantly higher than those of control group, the cytokines and other inflammatory mediators were significantly lower than those of control group, and the differences were statistically significant (P<0.05). Conclusion: Among patients undergoing gallstone surgery, laparoscopic surgery has better surgical indicators and lower complications. The expression changes of CCK, its receptors and inflammatory mediators during the perioperative period are different from those of small incision surgery. It is more suitable for patients undergoing gallstone surgery.
  • Article
    Efficacy of GnRH-a Combined with Laparoscopic Cyst Removal in the Treatment of Ovarian Endometriosis Cysts
    HE Li, BU Xiaoting
    2025, 23(19): 8-2. https://doi.org/10.14033/j.cnki.cfmr.2025.19.003
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    Objective: To study the therapeutic effect of gonadotropin-releasing hormone agonist (GnRH-a) combined with laparoscopic cyst removal for ovarian endometriosis. Method: 84 patients with ovarian endometriosis cysts admitted to the Obstetrics and Gynecology Department of Chenggu County Hospital from January 2023 to January 2024 were randomly divided into an observation group (n=43) and a control group (n=41). Both groups underwent laparoscopic cystectomy treatment, with the control group receiving a combination of gestrel and the observation group receiving a combination of GnRH-a. The efficacy, sex hormones [estradiol (E2), luteinizing hormone (LH), follicle stimulating hormone (FSH)], immune function indicators [T lymphocyte subsets (CD4+, CD8+, CD4+/CD8+)], adverse reactions, pregnancy and recurrence rates between two groups were compared. Result: The effective rate of the observation group was higher than that of the control group, and the difference was statistically significant (P<0.05). The levels of E2, LH, FSH, CD4+, CD4+/CD8+, incidence of adverse reactions, and recurrence rate in the observation group were lower than those in the control group, while the levels of CD8+ and pregnancy rate were higher than those in the control group, with statistically significant differences (P<0.05). Conclusion: Laparoscopic cystectomy combined with GnRH-a for the treatment of ovarian endometriosis cysts can enhance immune function, inhibit hormone release, and have a low postoperative recurrence rate and few adverse reactions. The medication is safe and reliable, and can also improve pregnancy rates.
  • Article
    Clinical Observation of Percutaneous Vertebroplasty in the Treatment of Old Unstable Osteoporotic Spinal Fractures
    XIE Liangliang
    2025, 23(19): 12-15. https://doi.org/10.14033/j.cnki.cfmr.2025.19.004
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    Objective: To explore the application value of percutaneous vertebroplasty in the treatment of old unstable osteoporotic spinal fractures. Method: 83 cases of old unstable osteoporotic spinal fractures in the hospital from September 2021 to September 2023 were selected, and divided into PVP group and PKP group according to surgical methods, with 41 and 42 patients in each group, respectively. PKP group underwent percutaneous kyphoplasty, while the PVP group underwent percutaneous kyphoplasty. The spinal condition (Cobb angle and anterior vertebral height), mobility (Oswestry disability index, ODI), the incidence of adverse reactions (respiratory/reproductive system infections, deep vein thrombosis, constipation, adjacent vertebral compression fractures) were compared between the two groups. Result: The anterior vertebral height of both groups of patients significantly increased 3 and 6 months after surgery, but the improvement of various indicators in the PKP group was better than that in the PVP group (P<0.05). The clinical indicators and postoperative recovery of the PVP group were superior to those of the PKP group, with statistically significant difference (P<0.05). 3 and 6 months after surgery, the ODI index scores of both groups of patientsdecreased significantly, and there was no significant difference in the level (P>0.05). The incidence of adverse reactions in the PVP group was slightly lower than that in the PKP group, but there was no statistically significant difference (P>0.05). Conclusion: For patients with old and unstable osteoporotic spinal fractures, percutaneous vertebroplasty can effectively improve spinal condition, increase daily activity level, and have a short recovery period. The treatment cost is also quite affordable. However, compared to kyphoplasty, the risk of pathological fractures after surgery is slightly higher. Therefore, when selecting a surgical plan, individual differences and the actual condition of the patient should be taken into account.
  • Article
    Application Effect of Lauromacrogol Sclerosing Foam in the Patients with Intracavitary Laser Closure Surgery for Varicosis of Great Saphenous Vein
    LIN Yuke
    2025, 23(19): 16-19. https://doi.org/10.14033/j.cnki.cfmr.2025.19.005
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    Objective: To investigate the application effect of lauromacrogol sclerosing foam in the patients with intracavitary laser closure surgery for varicosis of great saphenous vein. Method: 110 patients with varicosis of great saphenous vein in Second Hospital of Nanping City from March 2021 to December 2023 were divided into 55 cases in control group and in 55 cases observation group by the random number table. The control group were treated with intracavitary laser closure surgery, the observation group were treated with intracavitary laser closure surgery combined with lauromacrogol sclerosing foam. Then the total effective rates for varicosis of great saphenous vein, complication rates, saphenous nerve injury rates at different time after the surgery, saphenous nerve conduction indexes (conduction velocity, latency and wave amplitude) and life quality [chronic venous insufficiency questionnaire (CIVIQ score)] before and after the surgery of two groups were compared. Result: The total effective rates for varicosis of great saphenous vein of two groups were compared, the difference was statistically significant(P>0.05), the complication rates and saphenous nerve injury rates at different time after the surgery of observation group were significantly lower than those of control group (P<0.05), the saphenous nerve conduction indexes and CIVIQ score of two groups before the surgery were compared, the differences were not statistically significant(P>0.05). The conduction velocity, wave amplitude and CIVIQ score of observation group were significantly higher than those of control group, the latency were significantly lower than those of control group (P<0.05). Conclusion: The application effect of lauromacrogol sclerosing foam in the patients with intracavitary laser closure surgery for varicosis of great saphenous vein is good, and it can effectively control the saphenous nerve injury and is helpful to the improvement of life quality of patients, so its application value is higher.
  • Article
    Clinical Effect of Intraventricular Drilling Drainage Combined with Craniotomy Hematoma Clearance for the Treatment of Hypertensive Intracerebral Hemorrhage with Cerebral Herniation
    TANG Xingping, SUN Qiang, CHEN Xianyong
    2025, 23(19): 20-23. https://doi.org/10.14033/j.cnki.cfmr.2025.19.006
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    Objective: To analyze the therapeutic effect of using intraventricular drilling drainage combined with craniotomy hematoma removal surgery in the treatment of patients with hypertensive intracerebral hemorrhage and cerebral herniation. Method: 64 patients with hypertensive intracerebral hemorrhage and cerebral herniation admitted to Qiannan Traditional Chinese Medicine Hospital from June 2021 to August 2023 were selected as the observation subjects for this study. They were randomly divided into two groups using a number table method. The observation group (32 cases) received intraventricular drilling drainage combined with craniotomy hematoma removal surgery, while the control group (32 cases) received conventional decompression treatment. The clinical efficacy of two groups of patients after treatment was compared. The inflammatory response neurotransmitter indicators before and after treatment, i.e. procalcitonin (PCT), C-reactive protein (CRP), and interleukin-6 (IL-6), and the motor function assessment (FMA) score, the National Institutes of Health Stroke Scale (NIHSS) score, and the Barthel Index score for various scales of daily livingability were analyzed. Result: After treatment, it can be seen that the clinical efficacy of the observation group patients was higher than that of the control group patients. There was no statistically significant difference in inflammatory response neurotransmitter indicators, FMA scores, NIHSS scores, and Barthel index scores between two groups of patients before treatment intervention (P>0.05). After treatment, the inflammatory response neurotransmitter indicators, FMA score, NIHSS score, and Barthel index score of the observation group were better than those of the control group, with statistically significant difference (P<0.05). Conclusion: In the treatment of hypertensive intracerebral hemorrhage combined with cerebral herniation, the combination of intraventricular drilling drainage and craniotomy hematoma removal surgery can improve clinical efficacy, improve inflammatory response neurotransmitters. Compared to conventional treatment measures, it is more effective in reducing neurological damage. It can improve FMA score, and it contributes to the improvement of quality of life.
  • Article
    Effects of Different Laparoscopic Surgical Approaches on Perioperative Indicators, Stress Response, and Postoperative Complications in Patients with Acute Cholecystitis
    HU Yue, HU Heng, LI Yunkui
    2025, 23(19): 24-27. https://doi.org/10.14033/j.cnki.cfmr.2025.19.007
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    Objective: To investigate the effects of different laparoscopic surgical approaches on perioperative indicators, stress response, and postoperative complications in patients with acute cholecystitis. Method: A total of 315 patients with acute cholecystitis treated with laparoscopic surgery in the Third People's Hospital of Jingzhou City from January 2022 to September 2024 were selected as the study subjects. The patients were divided into a lateral group (n=165) and an anterograde/retrograde group (n=150) according to the laparoscopic surgical approach. The lateral group underwent lateral laparoscopic cholecystectomy, while the anterograde/retrograde group underwent either anterograde or retrograde laparoscopic cholecystectomy. The perioperative indicators (surgical time, drainage tube placement time, length of hospital stay, intraoperative bleeding volume and postoperative drainage volume), stress response [norepinephrine (NE), adrenocorticotropic hormone (ACTH), cortisol (Cor)], and postoperative outcomes were compared between the two groups. Result: The surgical time, length of hospital stay, and drainage tube placement time of the lateral group were shorter than those of the anterograde/retrograde group (P<0.05). Before surgery, there was no statistically significant difference in stress response between the two groups (P>0.05). 24 h and 72 h after surgery, the stress response in the lateral group was lower than that in the anterograde/retrograde group, and the difference was statistically significant (P<0.05). The total incidence rate of the lateral group was significantly lower than the anterograde/retrograde group, and the difference was statistically significant (P<0.05). Conclusion: The use of lateral laparoscopic surgical approach in patients with acute cholecystitis can reduce stress response, decrease bleeding volume, improve postoperative complications, and shorten hospitalization time.
  • Article
    Effect of Tanshinone ⅡA Sodium Sulfonate Injection Combined with Amiodarone Hydrochloride Injection on Ventricular Arrhythmia and its Effect on Heart Rate Variability
    CHEN Mingjun
    2025, 23(19): 27-31. https://doi.org/10.14033/j.cnki.cfmr.2025.19.008
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    Objective: To investigate the therapeutic effect of tanshinone IIA sodium sulfonate combined with amiodarone hydrochloride on ventricular arrhythmia (VA). Method: 98 VA patients treated in Qianjiang Central Hospital from January 2023 to January 2024 were selected and divided into combination group and routine group, with 49 cases in each group according to random number table method. The conventional group was treated with amiodarone hydrochloride injection, and the combined group was treated with tanshinone ⅡA sodium sulfonate injection. The clinical efficacy and adverse drug reactions were compared between the two groups. HRV [global standard deviation during sinus R-R (SDNN), mean standard deviation during RR (SDANN), root mean square of the difference between adjacent normal RR periods (RMSSD)], B-type natriuretic peptide (BNP), cardiac function indicators [left ventricular ejection fraction (LVEF), heart index (CI)] and 6 min walking distance (6MWD), cardiac function grade, inflammatory markers [tumor necrosis factor-α (TFN-α), interleukin-6 (IL-6), C-reactive protein (CRP)] were compared between the two groups before and after treatment. Result: The clinical effect of the combined group was significantly better than that of the conventional group, and the difference was statistically significant (P<0.05). After treatment, SDNN, SDANN, RMSSD, LVEF, CI and 6MWD were increased in 2 groups, the combined group was higher than the conventional group, and the difference was statistically significant (P<0.05). After treatment, BNP, TFN-α, IL-6 and CRP in 2 groups were decreased, the combined group was lower than the conventional group, and the difference was statistically significant (P<0.05). After treatment, the cardiac function grade of the combined group was significantly better than that of the conventional group, and the proportion of grade Ⅱ in the combined group was higher than that of the conventional group, the proportion of grade Ⅲ was lower than that of the conventional group, and the difference was statistically significant (P<0.05). There was no significant difference in the incidence of adverse drug reactions between the two groups (P>0.05). Conclusion: Tanshinone ⅡA sodium sulfonate injection combined with amiodarone hydrochloride injection can improve heart function and heart rate variability in VA patients, promote myocardial function recovery, and reduce inflammation. The side effects are mild.
    • Clinical practice
  • Clinical practice
    Clinical Efficacy of Adaptive Therapy for Acute Posterior Circulation Cerebral Infarction After Remote Ischemia
    ZHAO Xia
    2025, 23(19): 32-36. https://doi.org/10.14033/j.cnki.cfmr.2025.19.009
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    Objective: To explore the clinical efficacy of Remote Ischemic Post adaptation (RIPostC) in the treatment of acute posterior circulation cerebral infarction (APCI). Method: 100 APCI patients admitted to Xinhua Hospital of Ili Kazakh Autonomous Prefecture from May 2023 to April 2024 were randomly divided into experimental group (n=50) and control group (n=50). The control group received conventional treatment, while the experimental group received conventional treatment plus RIPostC treatment for 2 weeks. The modified Ranlin Scale (mRS) scores, Barthel Index (BI) scores, Extended National Institutes of Health Stroke Scale (e-NIHSS) scores, and incidence of adverse reactions during treatment in two groups before and after 2, 4, and 12 weeks of treatment were observed. Result: The total effective rate of the experimental group was higher than that of the control group, and the difference was statistically significant (P<0.05). There were statistically significant differences in the time factors, inter group factors, and time and inter group interactions of e-NIHSS, BI, and mRS scores between the two groups (P<0.05). After treatment, the BI scores of the experimental group were higher than those of the control group at all time points, while the e-NIHSS and mRS scores were lower than those of the control group, and the differences were statistically significant (P<0.05). There was no statistically significant difference in the total incidence of adverse reactions between the two groups (P>0.05). Conclusion: RIPostC treatment for APCI patients can significantly improve clinical outcomes, neurological function, and daily living abilities. It has good safety.
  • Clinical practice
    Study on the Clinical Efficacy of High-frequency Oscillating Pneumonia Machine Combined with Nebulized Inhalation in the Treatment of Hospital-acquired Pneumonia in Elderly Inpatients
    FAN Rusha
    2025, 23(19): 36-41. https://doi.org/10.14033/j.cnki.cfmr.2025.19.010
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    Objective: To investigate the clinical efficacy of high-frequency oscillatory sputum drainage machine combined with nebulization inhalation in the treatment of hospital-acquired pneumonia (HAP) in elderly hospitalized patients. Method: 100 elderly HAP patients admitted to Jinnan Branch of Jinjiang Hospital from January 2022 to January 2024 were randomly divided into control group (n=50) and experimental group (n=50). Both groups received nebulization treatment, and in addition, the control group received conventional sputum drainage treatment, while the experimental group received high-frequency oscillatory sputum drainage machine treatment. The oxygenation index (OI), C-reactive protein (CRP), blood routine [white blood cell count (WBC), neutrophil percentage (NEUT%)], lung function indicators [forced vital capacity (FVC), forced expiratory volume (FEV1)], symptom disappearance time, and acute and chronic health score (APACHE Ⅱ score) were compared between the two groups. Result: The cough cessation time, lung rales disappearance time, and fever duration were shorter, and the daily sputum volume was higher in the experimental group than in the control group, with statistically significant differences (P<0.05). After treatment, CRP, WBC, and NEUT% in the experimental group were lower than those in the control group, with statistically significant differences (P<0.05). The FVC, FEV1, and OI in the experimental group were better than those in the control group, with statistically significant differences (P<0.05). The APACHE Ⅱ score in the experimental group was lower than that in the control group, with statistically significant difference (P<0.05). Conclusion: The combination of high-frequency oscillatory sputum drainage machine and nebulization inhalation treatment for elderly HAP can achieve significant efficacy, reduce the incidence of complications, and improve the cure rate.
  • Clinical practice
    Effect of Insulin Combined with Medical Nutrition Therapy on Gestational Diabetes Mellitus
    HE Lilian
    2025, 23(19): 42-45. https://doi.org/10.14033/j.cnki.cfmr.2025.19.011
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    Objective: To investigate the effect of insulin combined with medical nutrition therapy on patients with gestational diabetes. Method: A total of 94 patients with gestational diabetes who received treatment in the hospital from March 2022 to March 2024 were selected as research samples and divided into groups according to different treatment intervention methods. Patients in the control group (47 cases) received insulin aspartate treatment, and patients in the observation group (47 cases) received medical nutrition therapy on the basis of insulin aspartate treatment. Blood glucose levels, nutritional indexes and serum factors before and after treatment were compared between the two groups, and adverse pregnancy outcomes of the two groups were recorded. Result: After treatment, the observation group blood glucose indexes were lower than control group (P<0.05). After treatment, the observation group indexes of serum total protein and serum albumin were higher than control group (P<0.05). After treatment, fasting insulin and cholesterol of the observation group were lower than control group, and the function index of islet β cell was higher than control group (P<0.05). Overall incidence of adverse pregnancy outcomes of the observation group was lower than the control group (P<0.05). Conclusion: The combination of insulin and medical nutrition therapy is effective in gestational diabetes patients, which can effectively reduce the blood sugar level of patients, improve nutritional indexes, regulate the islet function and cholesterol level, and reduce the risk of adverse pregnancy outcomes.
  • Clinical practice
    Effects of Xuanbi Qingfei Decoction Combined with Antibiotics in the Treatment of Severe Pneumonia in the Elderly
    HU Xuesong, WU Longchuan
    2025, 23(19): 46-49. https://doi.org/10.14033/j.cnki.cfmr.2025.19.012
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    Objective: To explore the efficacy of Xuanbi Qingfei Decoction combined with antibiotics in treating severe pneumonia in the elderly. Method: From June 2022 to June 2024, 84 elderly patients with severe pneumonia from Medical School of Yangzhou University were included. According to the coin throwing method, the patients were divided into test group (42 cases) and control group (42 cases). The control group received standard antibiotic therapy, while the trial group received Xuanbi Qingfei Decoction in addition to the standard treatment. The treatment period was 14 days. Differences in treatment efficacy, Traditional Chinese Medicine (TCM) syndrome scores, lung function, inflammatory markers, and disease severity [Acute Physiology and Chronic Health Evaluation Ⅱ (APACHE Ⅱ) scores] between the two groups were compared. Result: The overall effectiveness rate of the experimental group was higher than that of the control group (P<0.05). Before treatment, there was no significant difference in Traditional Chinese Medicine (TCM) syndrome scores between the two groups (P>0.05). After treatment, the experimental group showed lower scores in symptoms such as cough, fever, yellow or blood-tinged sputum, wheezing, chest tightness, and dry mouth compared to before treatment, and these scores were also lower than those of the control group (P<0.05). Before treatment, there was no significant difference in lung function levels between the two groups (P>0.05); however, after treatment, the experimental group showed higher FEV1, FVC, FEV1/FVC, PEF, and MVV than before treatment and higher than those of the control group (P<0.05). Before treatment, there was no significant difference in CRP and PCT levels, and APACHE Ⅱ scores between the two groups (P>0.05). After treatment, the experimental group had lower CRP and PCT levels, and APACHE II scores compared to before treatment, and also lower than those of the control group (P<0.05). Conclusion: Xuanbi Qingfei Decoction combined with antibiotics significantly enhances treatment efficacy, improves lung function and TCM syndrome scores, effectively reduces levels of inflammatory markers and the severity of the disease, and is well-tolerated in elderly patients with severe pneumonia.
  • Clinical practice
    Effect of MIPPO Combined with LCP on Patients with Distal TIbial Fracture
    LI Qiansong
    2025, 23(19): 50-53. https://doi.org/10.14033/j.cnki.cfmr.2025.19.013
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    Objective: To explore the effect of MIPPO and LCP in the treatment of distal tibial fractures. Method: 102 patients with distal tibial fracture who were treated in Guizhou Staff Hospital from June 2021 to August 2024. They were randomly divided into two groups: reference group, research group, with 51 cases in each group. Control group received open reduction + internal fixation with steel plate, and the study group received MIPPO+LCP. The excellent and good rate of ankle joint function and the expression of bone markers in the two groups were observed. Result: 3 months after operation, the excellent and good rate of ankle joint function in the study group was higher than reference group (P<0.05). Before operation, there was no statistically significant difference in OC, PⅠCP, BALP and PTH (P>0.05). 1 day and 3 months after operation, OC, PⅠCP, BALP and PTH in the study group were higher, with statistically significant difference (P<0.05). Conclusion: MIPPO+LCP can improve ankle joint function, enhance osteocyte activity and promote fracture healing in the treatment of distal tibial fracture. It has good application value.
  • Clinical practice
    Effect of Blood Perfusion Combined with Iodothyroxine on Patients with Acute Severe Organophosphate Pesticide Poisoning
    LI Li, HUANG Wei, XU Yong
    2025, 23(19): 53-56. https://doi.org/10.14033/j.cnki.cfmr.2025.19.014
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    Objective: To analyze the therapeutic effect of blood perfusion combined with iodothyroxine on patients with acute severe organophosphate pesticide poisoning. Method: Selecting 90 patients with acute severe organophosphate pesticide poisoning admitted to Tongren People's Hospital from January 2020 to August 2024. They were grouped according to different treatment plans. According to different treatment plans, they were divided into a control group of 40 cases and an observation group of 50 cases. During routine treatment, the control group was treated with iodipyrimidine. Hemoperfusion was applied in the observation group during the treatment with iodophosphatine. The treatment effects, cholinesterase (CHE) activity, aspartate aminotransferase (AST) levels, etc. of the two groups were compared. Result: The clinical symptom relief time and atropine dosage of the observation group were lower than those of the control group. The CHE activity was higher than that of the control group 6, 12, 24, and 48 h after treatment, and the difference was statistically significant (P<0.05). The levels of serum creatine kinase (CK), cardiac troponin I (cTnI), aspartate aminotransferase (AST), and alanine aminotransferase (ALT) of observation group were lower than those in the control group 48 h after treatment, and the expression of serum inflammation was lower than that in the control group, with statistically significant difference (P<0.05). There was no statistically significant difference in the incidence of complications and mortality between the two groups (P>0.05). Conclusion: The combination of hemoperfusion and iodothyroxine can improve the CEH activity in patients with acute severe organophosphate pesticide poisoning, alleviate liver and myocardial damage.
  • Clinical practice
    Efficacy of Ulinastatin Combined with Octreotide in the Treatment of Acute Pancreatitis and its Adverse Reactions
    RUAN Shunxing, CHEN Yazhi
    2025, 23(19): 57-60. https://doi.org/10.14033/j.cnki.cfmr.2025.19.015
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    Objective: To analyze the efficacy of ulinastatin combined with octreotide in patients with acute pancreatitis and its adverse reactions. Method: A retrospective analysis was conducted on the clinical data of 82 patients with acute pancreatitis admitted to First Hospital of Putian City from June 2022 to February 2024. All selected patients were divided into two groups with 41 cases in each group by treatment methods. The control group took octreotide alone, and the observation group added ustervastatin. The clinical efficacy, symptom disappearance and hospitalization time, white blood cell count (WBC), serum amylase (AMS), urinary amylase (UAMY) levels, serum inflammatory factors [interleukin-10 (IL-10), C-reactive protein (CRP), tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6)], and adverse reactions of two groups were compared. Result: After treatment, the clinical effect of observation group was higher than that of control group. The symptoms disappeared in the observation group and the hospitalization time was shorter than that in the control group. The levels of WBC, AMS, UAMY, CRP, IL-6 and TNF-α were lower than those of control group, and the levels of IL-10 were higher than those of control group, with statistically significant difference (P<0.05). The adverse reactions of the two groups were compared, with no statistically significant difference (P>0.05). Conclusion: The combination of ustepidem and octreotide can effectively improve the levels of detection factors: WBC in patients with acute pancreatitis, alleviate inflammation, shorten the duration of symptoms, and do not increase adverse reactions, which has higher safety.
  • Clinical practice
    Effect of Banxia Baizhu Tianma Decoction on Patients with Angina Pectoris of Coronary Heart Disease
    JIANG Huinan, LUAN Jianwei, JIANG Weidong
    2025, 23(19): 60-63. https://doi.org/10.14033/j.cnki.cfmr.2025.19.016
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    Objective: To explore the curative effect of Banxia Baizhu Tianma Decoction in patients with angina pectoris of coronary heart disease. Method: A total of 100 patients with angina pectoris of coronary heart disease admitted to Nantong Hospital of Traditional Chinese Medicine were enrolled and randomly divided into control group (routine western medicine) and observation group (Banxia Baizhu Tianma Decoction on basis of control group) from August 2022 and April 2024, with 50 cases in each group. All patients were treated for 2 months. The response rate of treatment, cardiac function [left ventricular end-systolic diameter (LVESD), left ventricular end-diastolic diameter (LVEDD), left ventricular ejection fraction (LVEF)], hemorheologyindexes (plasma viscosity, equation K value of erythrocyte sedimentation rate, platelet aggregation rate) and incidence of adverse events in the two groups were compared. Result: After treatment, effective rate of treatment in the observation group was higher than that in the control group (P<0.05). LVESD and LVEDD were lower (P<0.05), while LVEF was higher in observation group (P<0.05). The plasma viscosity, equation K value of erythrocyte sedimentation rate and platelet aggregation rate were lower in observation group than control group (P<0.05). The difference in incidence of adverse reactions between observation group and control group was not statistically significant (P>0.05). Conclusion: Banxia Baizhu Tianma Decoction can significantly improve cardiac function and hemorheology indexes in patients with angina pectoris of coronary heart disease, which will not significantly increase the incidence of adverse reactions, with good safety.
  • Clinical practice
    Effect of Chaihu Kegu Oyster Decoction on Esophageal Reflux Gastritis
    LI Liyuan
    2025, 23(19): 64-67. https://doi.org/10.14033/j.cnki.cfmr.2025.19.017
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    Objective: To evaluate the efficacy of Chaihu Kegu Oyster Decoction in the treatment of esophageal reflux gastritis. Method: A total of 206 patients diagnosed with esophageal reflux gastritis admitted to the hospital from June 2022 to June 2024, were randomly assigned to two groups. The control group received rabeprazole sodium enteric-coated tablets, while the study group was administered Chaihu Kegu Oyster Decoction in addition to treatment regimen of the control group. Both groups underwent an 8-week treatment period. Traditional Chinese Medicine (TCM) syndrome scores, severity of reflux disease, and esophageal motor function were assessed and compared between the two groups. Result: 8 weeks after treatment, the study group exhibited significantly lower scores for acid reflux, retrosternal burning, upper abdominal discomfort, and noise compared to the control group (P<0.05). After 4 and 8 weeks treatment, RDQ scores in the study group were significantly lower than those in the control group (P<0.05). 8 weeks after treatment, the amplitude of esophageal constriction waves was higher, the transmission speed of esophageal peristaltic waves was faster, and the average duration of esophageal constriction was shorter in the study group compared to the control group (P<0.05). The therapeutic effect was superior in the study group (P<0.05), with lower rates of adverse reactions and recurrence (P<0.05). Conclusion: Chaihu Kegu Oyster Decoction effectively improves esophageal motor function; alleviates clinical symptoms, such as acid reflux and upper abdominal discomfort; reduces recurrence rates; and demonstrates safety.
  • Clinical practice
    Comparative Study on the Analgesic Effects of Local Wound Infiltration Anesthesia and Lumbar Muscle Block Anesthesia After Laparoscopic Colorectal Cancer Surgery
    MENG Pei, ZHU Shaohui
    2025, 23(19): 67-70. https://doi.org/10.14033/j.cnki.cfmr.2025.19.018
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    Objective: To compare the analgesic effects of local wound infiltration anesthesia and lumbar muscle block anesthesia after laparoscopic colorectal cancer surgery. Method: 90 patients with colorectal cancer who underwent laparoscopic surgery at the Second People's Hospital of Jiaozuo City from January to June 2024 were selected as the study subjects. They were randomly divided into two groups of 45 patients each using a random number table method. The control group received lumbar muscle block anesthesia, while the observation group received local wound infiltration anesthesia. The pain scores, PCIA compression frequency, first additional analgesia time, postoperative exhaust time and adverse reactions between two groups were compared. Result: The NRS scores of the observation group were lower than those of the control group at 4, 24, and 48 hours after surgery in both resting and exercise states, and the difference was statistically significant (P<0.05). The observation group had fewer PCIA compressions than the control group, and the first additional analgesia and postoperative exhaust time were shorter than those of the control group, with statistically significant differences (P<0.05). There was no statistically significant difference in adverse reactions between the two groups (P>0.05). Conclusion: Local wound infiltration anesthesia has a comparable effect to lumbar muscle block anesthesia in postoperative analgesia for laparoscopic colorectal cancer. Its operation is simple, the effect is accurate, and the medical cost is low.
  • Clinical practice
    Clinical Study on the Effect of Limb Placement Combined with Weight Loss Walking Training on Balance and Walking Ability in Stroke Patients with Hemiplegia
    LIN Zhigang, ZHOU Guoyan
    2025, 23(19): 71-74. https://doi.org/10.14033/j.cnki.cfmr.2025.19.019
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    Objective: To explore the effects of good limb position placement combined with body weight support treadmill training on balance and walking ability in stroke patients with hemiplegia. Method: 61 stroke patients treated in the hospital from March 2021 to June 2024 were randomized by envelope method: 31 in the observation group, and 30 in the control group. Both groups received conventional rehabilitation training, while the observation group added good limb position placement and body weight support treadmill training on the basis of the control group. After 12 weeks of continuous treatment, the Berg Balance Scale (BBS) scores and 10-meter walk test (10MWT) were used to evaluate the balance and walking ability of the patients before and after training. Result: After 12 weeks of treatment intervention, the BBS scores and 10MWT speed of both groups were higher than before training, the balance and walking ability of both groups improved significantly, and the observation group showed better improvement in scale scores than the control group (P<0.05). Conclusion: Adopting good limb position placement combined with body weight support treadmill training for stroke patients with hemiplegia can improve their balance and walking ability.
  • Clinical practice
    Clinical Effect of Xingnaojing Injection on Cognitive Impairment After Aneurysmal Subarachnoid Hemorrhage (aSAH)
    QIN Jun, HE Ting, XIA Jin, ZHANG Dong, QUAN Liuyan
    2025, 23(19): 75-78. https://doi.org/10.14033/j.cnki.cfmr.2025.19.020
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    Objective: To investigate the clinical efficacy of Xingnaojing injection in treating cognitive impairment after aneurysmal subarachnoid hemorrhage (aSAH). Method: A total of 60 patients with aSAH admitted to the hospital from January 2023 to June 2024 were randomly divided into control group (n=30) receiving conventional treatment and study group (n=30) receiving Xingnaojing injection. The levels of inflammatory factors, cerebral blood flow velocity, and cognitive function between two groups are compared. Result: After intervention, the levels of CRP, NSE, IL-6 and TNF-α showed a decreasing trend in both groups, with the study group showing a more significant decrease (P<0.05). The two intervention groups showed a decreasing trend in cerebral blood flow velocity, with the study group showing a more significant decrease (P<0.05). After intervention, the MOCA scores showed an upward trend in both groups, with the study group showing a more significant increase (P<0.05). Conclusion: Xingnaojing injection can regulate cerebral blood flow velocity, reduce inflammatory response, and have significant therapeutic effects on improving cognitive impairment in patients with aSAH.
  • Clinical practice
    Clinical Effect of Laparoscopic Lesion Resection Combined with GnRH-a in the Treatment of StageⅡ~Ⅳ Endometriosis
    MA Liangjuan
    2025, 23(19): 78-81. https://doi.org/10.14033/j.cnki.cfmr.2025.19.021
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    Objective: To observe the clinical efficacy of laparoscopic lesion resection combined with gonadotropin-releasing hormone agonist (GnRH-a) in the treatment of stage Ⅱ~Ⅳ endometriosis (EMT). Method: A retrospective analysis was conducted on the clinical data of 64 patients with stage Ⅱ~Ⅳ EMT admitted to the Third People's Hospital of Jingzhou City from January 2021 to April 2022. According to different treatment methods, they were divided into control group and combination group, with 32 cases in each group. The control group was treated with laparoscopic lesion resection, while the combination group was treated with GnRH-a after laparoscopic lesion resection. The clinical treatment efficacy, clinical symptom related indicators (dysmenorrhea pain level, ovarian volume, endometrial thickness), Follicle Stimulating Hormone (FSH), Luteinizing Hormone (LH), Estradiol (E2), and Carbohydrate Antigen 125 (CA125) between two groups were compared. Both groups completed at least 2 years of follow-up, and the recurrence rates 1 and 2 years after surgery were recorded. Result: The effective rate of the combined treatment group was higher than that of the control group, and the difference was statistically significant (P<0.05). Compared with before treatment, the VAS scores, endometrial thickness, FSH, LH, E2, CA12 were lower, and the ovarian volume was smaller in both groups after treatment, with statistically significant difference (P<0.05). After treatment, compared with the control group, the combination group had lower VAS scores, endometrial thickness, FSH, LH, E2, CA12, and smaller ovarian volume, with statistically significant difference (P<0.05). The recurrence rates of the combined group 1 and 2 years after surgery were lower than those of the control group, and the difference was statistically significant (P<0.05). Conclusion: Laparoscopic lesion resection combined with GnRH-a treatment for stage Ⅱ~Ⅳ EMT patients can alleviate patient pain, facilitate the recovery of ovarian volume and endometrium, effectively improve patient sex hormone levels, and have a low postoperative disease recurrence rate.
  • Clinical practice
    Efficacy and Safety of Betahistine Tablets Combined Treatment with Omalizumab in Chronic Spontaneous Urticaria
    TAN Fenfang, ZUO Yuhui, ZOU Song
    2025, 23(19): 82-85. https://doi.org/10.14033/j.cnki.cfmr.2025.19.022
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    Objective: To evaluate the effect and safety of combined application of levocetirizine dihydrochloride tablets and omalizumab patients with chronic spontaneous urticaria (CSU). Method: A total of 102 patients with CSU from Guiping People's Hospital from March to September 2023 were included. The patients were divided into two groups according to the randomized numerical table method. The control group (n=51) was treated with levocetirizine dihydrochloride tablets, and the observation group (n=51) was treated with levocetiriz dihydrochloride tablets combined with omalizumab. The clinical efficacy, 7-day urticaria activity score (UAS7), urticaria control (UCT), dermatology life quality index (DLQI), serological indicators [immunoglobulin E (IgE), C-reactive protein (CR)], and safety of the two groups were evaluated. Result: After 6 months of treatment, the clinical efficacy, IgE and UCT of the group were higher than those of the control group, and the UAS7, DLQI, and CRP were lower than those of the control group, with statistically significant difference (P<0.05). In terms of adverse reactions, there was no significant difference between 5.88% of observation group and 3.92% of control group (P>0.05). Conclusion: The combination of benzenesulfestatin tablets and omazumab in CSU patients can improve the overall efficacy, enhance the disease control effect, improve the quality of life, and regulate the level of IgE and CRP. It has good safety.
    • Medical technology and clinical
  • Medical technology and clinical
    Significance of Preoperative Gene Examinations in Posterior Scleral Reinforcement of Pathological Myopia
    LIN Yanyu, LI Pengting, XIAO Chunting, LI Chunhua, HUA Chengzhou, XIE Jiangbin
    2025, 23(19): 86-89. https://doi.org/10.14033/j.cnki.cfmr.2025.19.023
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    Objective: To explore the significance of gene examinations before posterior scleral reinforcement (PSR) in pathological myopia patients, and to compare the curative effects of PSR in patients with positive and negative gene mutations in pathological myopia. Method: Patients with pathological myopia who underwent PSR surgery in Quanzhou Maternal and Child Health Hospital/Children's Hospital, Fujian Province from September 2019 to November 2020 were selected as the research subjects for PSR. Medical exome sequencing is used to detect whether there are genetic variations that match the clinical phenotype of pathological myopia. The patients were observed for 24 months before PSR and followed up for 24 months after PSR. The changes in best corrected visual acuity (BCVA), diopter (D), and axial length (AL) before and after PSR were observed. Paired t test was adopted. Independent sample t tests were used to compare the differences in BCVA, diopter increase and AL increase before and after the operation between gene-positive and gene-negative patients. Result: The preoperative BCVA of positive patients was (0.35±0.24), and the postoperative BCVA was (0.51±0.36), with statistically significant difference (P<0.05). The preoperative diopter of positive patients increased by (1.16±0.21) D/ year, and the postoperative diopter increased by (0.05±0.72) D/ year, with statistically significant difference (P<0.05). The preoperative AL increase of positive patients was (0.49±0.21) mm/ year, and the postoperative AL increase was (0.22±0.18) mm/ year, with statistically significant difference (P<0.05). The preoperative AL increase of negative patients was (0.48±0.25) mm/ year, and the postoperative AL increase was (0.37±0.24) mm/ year, with statistically significant difference (P<0.05). Conclusion: PSR is effective for patients with pathological myopia, whether the gene test is positive or negative. Postoperative BCVA is improved compared with the preoperative BCVA. Postoperative diopter growth and AL growth delay compared with those before surgery. Although the preoperative BCVA of gene positive patients is significantly worse than those of negative patients, PSR is effective in both groups, and there is no significant difference in curative effect.
  • Medical technology and clinical
    Impact of Early Pulmonary Rehabilitation Grading Management on Exercise Endurance and Quality of Life in AECOPD Patients
    JIANG Xiaoling, WANG Ling, WANG Ning
    2025, 23(19): 90-93. https://doi.org/10.14033/j.cnki.cfmr.2025.19.024
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    Objective: To explore the effect of early pulmonary rehabilitation grading management on exercise endurance and quality of life in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Method: A total of 110 AECOPD patients admitted to the First Affiliated Hospital of Bengbu Medical University from May 2022 to October 2024 were selected and randomly divided into two groups through random number table. The control group (n=54) received routine pulmonary rehabilitation management, while the observation group (n=56) received early pulmonary rehabilitation grading management. The compliance of two groups with rehabilitation exercise, 6-minute walk test (6MWT), and COPD health-related quality of life scale (COPD-QOL) scores were compared. Result: Compared with before intervention, both groups showed an increasing trend in their adherence to correct exercise, conscious exercise on time, systematic completion of exercise compliance scores, and 6MWT after one month of intervention. The COPD-QOL scale scores for daily living ability, social activity status, anxiety symptoms, and depression symptoms all showed a decreasing trend, and the differences were statistically significant (P<0.05). Among them, the observation group patients’ adherence to correct exercise, conscious exercise on time, systematic completion of exercise compliance scores, and 6MWT were significantly higher than those of the control group during the same period, while the COPD-QOL scale scores were significantly lower than those of the control group during the same period, and the differences were statistically significant (P<0.05). Conclusion: Early pulmonary rehabilitation grading management can effectively improve the rehabilitation exercise compliance, exercise endurance, and quality of life of AECOPD patients.
  • Medical technology and clinical
    Characteristics of Peripheral Blood Cells of Patients with Dengue Fever
    LIANG Guilan, GE Jingjing, YU Zhaobin
    2025, 23(19): 94-96. https://doi.org/10.14033/j.cnki.cfmr.2025.19.025
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    Objective: To investigate the changes of peripheral blood cell count and clinical features of early dengue fever patients. Method: 63 cases of early dengue fever diagnosed and treated from August to November 2024 were taken as dengue fever group, and 51 cases of other viral infections diagnosed and treated in January 2025 were taken as other viral groups, and 56 cases of bacterial infection diagnosed and treated from January to October 2024 were taken as bacterial infection group. A total of 35 healthy volunteers who went to the hospital for physical examination from May to October 2024 were selected as the healthy control group. Peripheral venous blood of all subjects was collected after inclusion for whole blood cell test. The differences and characteristics of blood cell indexes in different groups were compared. Result: It was determined that the white blood cells (WBC) and platelets (PLT) in the dengue fever group were both relatively low, and the difference was statistically significant (P<0.05). There was no statistically significant difference in neutrophil count (NE) between the dengue fever group and the healthy control group (P>0.05). The neutrophil count (NE) in the dengue fever group was lower than that in other virus groups and bacterial infection groups, and the difference was statistically significant (P<0.05). The lymphoid count (LYM) in the dengue fever group was lower than that in the healthy control group, and the difference was statistically significant (P<0.05). The lymphoid count (LYM) in the dengue fever group was higher than that in the virus group and the bacterial infection group, and the difference was statistically significant (P<0.05). The monocyte count (MON0) in the dengue fever group was higher than that in the bacterial infection group and the healthy control group, and the difference was statistically significant (P<0.05). Compared with other virus groups, the difference was not statistically significant (P>0.05). There was no statistically significant difference in hemoglobin (HGB) and hematocrit (HCT) between the dengue fever group and the other groups (P>0.05). Conclusion: The peripheral blood cell count of early dengue fever patients will change significantly, which is different from other viral and bacterial infections. The detection of blood cells can provide evidence for early diagnosis and treatment of dengue fever and the evaluation of the outcome of the disease, which has important clinical significance.
  • Medical technology and clinical
    Exploration of the Value of CT Quantitative Parameters in the Diagnosis of NAFLD and Evaluation of Patient Condition
    CHEN Shenghui, XIAN Weibin
    2025, 23(19): 97-100. https://doi.org/10.14033/j.cnki.cfmr.2025.19.026
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    Objective： To analyze the value of quantitative computed tomography (CT) parameters of liver and abdominal fat in the diagnosis and evaluation of non-alcoholic fatty liver disease (NAFLD). Method： 50 NAFLD patients who visited Changpo Branch of Gaozhou People's Hospital in Guangdong Province from September 2022 to September 2024 were selected as the observation group， and 50 non NAFLD patients who underwent physical examinations during the same period were selected as the control group. Clinical data of all subjects， as well as CT quantitative measurement of abdominal fat area values [total fat (TF)， subcutaneous fat (SF)， visceral fat (VF)， subcutaneous fat thickness， intermuscular fat (IMF)] was collected and oragized， the visceral to abdominal fat ratio (V/T) was calculated， and multivariate logistic regression analysis was conducted to analyze the relationship between the above parameters and NAFLD. ROC curve analysis was used to evaluate its diagnostic value for NAFLD， and further analyze its relationship with the severity of NAFLD. Result： There was no statistically significant difference in subcutaneous fat thickness and IMFA between the two groups (P>0.05)， while BMI， TFA， SFA， VFA， and V/T were all higher in the observation group than in the control group， with statistically significant differences (P<0.05). Through multiple logistic regression analysis， SFA， VFA， and V/T indicators were found to be independent risk factors for NAFLD， with statistically significant differences (P<0.05). The areas under the ROC curves of SFA， VFA， and V/T for diagnosing NAFLD were 0.635， 0.740， and 0.679， respectively， with statistically significant differences (P<0.05). After determining the critical values， their sensitivities and specificities with VFA had the highest diagnostic value. SFA， VFA， and V/T in patients with mild， moderate， and severe NAFLD increased sequentially， with statistically significant differences (P<0.05). Conclusion： The quantitative CT parameters SFA， VFA， and V/T of liver and abdominal fat are closely related to NAFLD and have certain diagnostic value for NAFLD. VFA has the highest diagnostic value and is closely related to the severity of the patient's condition.
  • Medical technology and clinical
    Value Analysis of Serum sFLC and ADA Combined with Immunoglobulin in Diagnosis of Multiple Myeloma
    LI Yan
    2025, 23(19): 100-103. https://doi.org/10.14033/j.cnki.cfmr.2025.19.027
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    Objective: To investigate the diagnostic value of serum free 1ight chain (sFLC), adenosine deaminase (ADA) and immunoglobulin in multiple myeloma. Method: A total of 103 newly diagnosed multiple myeloma patients admitted to Zhaoqing First People's Hospital from December 2020 to December 2023 were retrospectively selected, and 100 healthy patients from the physical examination center during the same period were selected as the control group. The levels of sFLC-λ, ADA and IgG were compared between patients with multiple myeloma and control group. The risk factors of patients with multiple myeloma were analyzed. The levels of sFLC-λ, ADA and IgG were taken as independent variables and the patients with multiple myeloma as dependent variables. Binary logistic regression was included to evaluate the value of the combined diagnosis of multiple myeloma with sFLC-λ, ADA and IgG, and the ROC curve of the combined diagnosis of multiple myeloma with sFLC-λ, ADA and IgG was drawn. Result: Compared with the control group, the levels of sFLC-λ, ADA and IgG in multiple myeloma patients were higher (P<0.05). The AUC of SCL-λ, ADA and IgG in the diagnosis of multiple myeloma were 0.844 (95%CI: 0.775~0.913), 0.759 (95%CI: 0.681~0.837), 0.840 (95%CI: 0.775~0.908) and 0.873 (95%CI: 0.799~0.928). The sensitivity was 82.55%, 80.88%, 76.47%, 84.93%. And the specificity was 76.48%, 62.06%, 74.24%, 77.92%. Conclusion: Serum sFLC and ADA combined with immunoglobulin have high diagnostic value in the diagnosis of multiple myeloma, which is helpful for early detection and intervention.
  • Medical technology and clinical
    Application Value of Pulse Oscillation Pulmonary Function Test in the Diagnosis of Bronchial Asthma in Preschool Children
    LIN Jiayuan, LIN Liping, LIU Fangyi, TAO Yinglin, OUYANG Yafang
    2025, 23(19): 104-107. https://doi.org/10.14033/j.cnki.cfmr.2025.19.028
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    Objective: To explore the application value of pulse oscillation (IOS) pulmonary function test in the diagnosis of bronchial asthma in preschool children. Method: 102 children with bronchial asthma admitted to Jinjiang Hospital from February 2023 to February 2024 were selected as the bronchial asthma group, and another 60 healthy children who underwent physical examinations during the same period were selected as the control group. IOS lung function tests were performed on all children, and they were divided into three subgroups according to the severity of bronchial asthma: mild group (n=35), moderate group (n=43), and severe group (n=24). The differences in IOS lung function test parameters [impedance at 5 Hz oscillation frequency (R5), impedance at 20 Hz oscillation frequency (R20), airway resistance difference at 5 Hz and 20 Hz oscillation frequency (R5-R20), and total respiratory impedance (Zrs)] were compared among the groups, and the differences were plotted. Receiver operating characteristic (ROC) curve analysis of the diagnostic value of IOS lung function test parameters for bronchial asthma in preschool children was conducted. Result: It is shown that the IOS lung function test parameters R5, R20, R5-R20, and Zrs levels in the bronchial asthma group were higher than those in the control group (P<0.05). The IOS lung function test parameters R5, R20, R5-R20, and Zrs levels in children with severe bronchial asthma were higher than those in the moderate and mild groups, and the IOS lung function test parameters R5, R20, R5-R20, and Zrs levels in children with moderate bronchial asthma were higher than those in the mild group (P<0.05). ROC curve analysis showed that the AUC (95% CI) of IOS lung function test parameters R5, R20, R5-R20, and Zrs for diagnosing bronchial asthma in preschool children were 0.758 (0.683~0.834), 0.842 (0.784~0.901), 0.847 (0.787~0.906), and 0.868 (0.810~0.927), respectively. The sensitivity was 63.7%, 62.7%, 80.4% and 81.4%, and the specificity was 78.3%, 86.7%, 81.7% and 83.3%. Conclusion: IOS lung function test parameters R5, R20, R5-R20, and Zrs have certain diagnostic value for bronchial asthma in preschool children. In clinical practice, the level of IOS lung function test parameters can be comprehensively analyzed to assist in the early diagnosis and treatment of bronchial asthma in preschool children.
  • Medical technology and clinical
    Value of Homocysteine, Cystatin C, and High-Sensitivity C-Reactive Protein Combined Detection in the Early Diagnosis of Diabetic Nephropathy
    ZHAO Yunjuan, WU Jiayi, SHEN Hanchan, FAN Jing
    2025, 23(19): 108-111. https://doi.org/10.14033/j.cnki.cfmr.2025.19.029
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    Objective: To explore the value of combined detection of homocysteine (Hcy), cystatin C (Cys C) and high-sensitivity C-reactive protein (hs-CRP) in the early diagnosis of diabetic nephropathy. Method: 82 patients with diabetic nephropathy treated in Jiangsu Shengze Hospital from February 2021 to February 2023 were included in the observation group. Another 82 patients with diabetes mellitus alone were selected as the control group during the same period. The levels and positive rates of Hcy, Cys C and hs-CRP were compared between the two groups. The diagnostic efficacy of the combined detection of Hcy, Cys C and hs-CRP in diabetic nephropathy was analyzed using the receiver operating characteristic (ROC) curve. Result: The levels of Hcy, Cys C and hs-CRP in the observation group were (22.68±2.58), (2.39±0.49) and (8.58±1.03), respectively, which were significantly higher than were (12.54±1.74), (1.12±0.12) and (2.91±0.42) in the control group (P<0.05). The positive rates of Hcy, Cys C and hs-CRP, as well as the combined detection, were 68.29%, 67.07%, 74.39% and 96.34%, respectively, in the observation group, which were significantly higher than 21.95%, 9.76%, 17.07% and 35.37% in the control group (P<0.05). ROC analysis showed that the sensitivity and specificity of combined detection of Hcy, Cys C and hs-CRP for diagnosing diabetic nephropathy were 96.3% and 96.3%, respectively, with an area under the curve (AUC) of 0.955, which was higher than any single test. Conclusion: The combined detection of Hcy, Cys C and hs-CRP in the early diagnosis of diabetic nephropathy shows high diagnostic efficacy. Compared with individual tests, the combined detection method has higher sensitivity and specificity in diagnosing diabetic nephropathy, effectively aiding in the early identification and intervention of patients with diabetic nephropathy.
  • Medical technology and clinical
    Value of Ultrasound Hemodynamic Parameters and Real-time Shear Wave Elastography Quantitative Parameters in Predicting Acute Kidney Injury After Kidney Transplantation
    SU Juan
    2025, 23(19): 111-114. https://doi.org/10.14033/j.cnki.cfmr.2025.19.030
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    Objective: To explore the value of ultrasound hemodynamic parameters and real-time shear wave elastography (SWE) quantitative parameters in predicting acute kidney injury (AKI) after kidney transplantation. Method: 52 renal transplant patients who were undergoing re-examination in Xintai People's Hospital from October 2020 to September 2023 were selected, all of whom were underwent color Doppler ultrasound examination. Hemodynamic parameters (peak flow velocity, RI and PI), and SWE quantitative parameters (renal sinus, renal cortex and medullary elastic modulus) were collected from the renal aorta, renal segmental artery, and renal vertebral inter lobar artery. The occurrence of AKI within 6 months after surgery was statistically analyzed, and univariate and multivariate logistic regression analysis was conducted to clarify the predictive value of combined diagnosis. Result: Among 52 kidney transplant patients, 13 cases developed AKI. In the renal diameter, compared with non AKI group, the AKI group was shorter, and the difference was statistically significant (P<0.05). In the RI, PI, and elastic modulus of renal cortex, compared with non AKI group, the AKI group was higher, and the difference was statistically significant (P<0.05). The results of multivariate logistic regression analysis showed that renal vertebral inter lobar artery RI, renal vertebral inter lobar artery PI, and renal cortical elastic modulus were independent risk factors for AKI after kidney transplantation (P<0.05). ROC curves were plotted to show that the areas under the curves of the RI, PI and elastic modulus of the renal cortex for predicting renal transplant induced AKI were 0.662, 0.780, 0.732 and 0.819, respectively. Conclusion: The combination of ultrasound hemodynamic parameters and SWE quantitative parameters can be applied to determine AKI after kidney transplantation, with high predictive efficacy.
    • Modern nursing
  • Modern nursing
    Clinical Study of Traditional Chinese Medicine Nursing Program Led by Bian-Shi-Warm Moxibustion on Deficiency Cold Type Chronic Gastritis
    CHEN Tuanyou, LONG Yajie, YE Feiyan
    2025, 23(19): 115-119. https://doi.org/10.14033/j.cnki.cfmr.2025.19.031
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    Objective: To explore the clinical application of traditional Chinese medicine nursing program led by stone needle warm moxibustion on chronic gastritis of asyngeal cold type. Method: 60 patients with chronic gastritis treated in Yangjiang Hospital of Traditional Chinese Medicine from October 2023 to August 2024, all of whom were deficient cold type in TCM. They were selected and divided into control group (30 cases) and experimental group (30 cases) according to computerized randomized control method. The patients in two groups were treated according to the modern medical routine of chronic gastritis, and given conventional modern medical nursing to the control group. The patients in the experimental group were treated with traditional Chinese medicine nursing program led by stone needle temperature moxibustion on the basis of the control group. The changes of TCM syndrome scores, quality of life (SF-36), sleep quality (Pittsburgh Sleep Quality Index, PSQI), anxiety (self-rating Anxiety Scale, SAS) and depression (Self-rating Depression Scale, SDS), compliance and satisfaction were compared between the two groups before and after nursing intervention. Result: Compared with the control group, the abdominal pain relief time, acid reflux relief time and hospital stay of experimental group after nursing intervention were lower, and the difference was statistically significant (P<0.05). The scores of each syndrome in wot groups decreased, and the experimental group was lower than the control group after nursing intervention, and the difference was statistically significant (P<0.05). The scores of SAS, PSQI and SDS were decreased, and the SF-36 scores were increased, the difference was statistically significant (P<0.05). Compared with the control group, after nursing intervention, the scores of SAS, PSQI and SDS in the experimental group were lower, and the scores of SF-36 were higher, with statistically significant difference (P<0.05). The nursing compliance rate in the control group was higher than the experimental group, with statistically significant difference (P<0.05). The nursing satisfaction rate of the control group was higher than the experimental group, with statistically significant difference (P<0.05). Conclusion: The traditional Chinese medicine nursing program led by stone Needle temperature moxibustion can significantly reduce the symptoms of patients with asi-cold type chronic gastritis, improve the quality of life and sleep quality of patients, the anxiety and depression of patients were reduced, the degree of gastric mucosal erosion and inflammation of patients was improved, and the patients have high compliance and satisfaction with nursing.
  • Modern nursing
    Application Effect of Graded Nursing Mode in Emergency Nursing of Patients with Acute Pancreatitis and its Impact on Prognosis
    KANG Jiejie, YAO Junxi, WANG Yin’e, XIE Ping
    2025, 23(19): 119-122. https://doi.org/10.14033/j.cnki.cfmr.2025.19.032
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    Objective: To explore the application effect of graded nursing mode in emergency nursing of patients with acute pancreatitis and its impact on prognosis. Method: A total of 106 patients with acute pancreatitis admitted to the First Affiliated Hospital of Bengbu Medical College from June 2021 to June 2024 were selected. The patients were randomly divided into two groups with random number table: control group (n=52, receiving routine nursing intervention) and observation group (n=54, receiving graded nursing intervention). The emergency treatment time and clinical symptom relief time between two groups were recorded and compared. Before and after intervention, the psychological status of patients with Self Rating Anxiety Scale (SAS) and Self Rating Depression Scale (SDS) was evaluated, and the incidence of complications between the two groups was compared. Result: The waiting time, triage evaluation time, emergency observation time, and relief time of abdominal pain, fever, nausea, and vomiting in the observation group were all shorter than those in the control group (P<0.05). After intervention, both groups of patients showed a decreasing trend in SAS and SDS scores compared to before intervention (P<0.05). After intervention, the SAS and SDS scores of the observation group were lower than those of the control group at the same time (P<0.05). The incidence of complications in the observation group was lower than the control group (P<0.05). Conclusion: The hierarchical nursing model can effectively shorten the emergency treatment time of patients with acute pancreatitis, alleviate clinical symptoms, improve adverse psychological states, and reduce the incidence of complications.
  • Modern nursing
    Effect of Motivational Psychological Care Combined with Cognitive-behavioral Intervention on Stigma and Self-management Ability of Patients with Urinary Incontinence After Prostate Cancer Surgery
    DONG Lingyu
    2025, 23(19): 123-126. https://doi.org/10.14033/j.cnki.cfmr.2025.19.033
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: To investigate the effect of motivational psychological nursing combined with cognitive behavioral intervention on stigma and self-management ability of patients with urinary incontinence after prostate cancer surgery. Method: A total of 80 patients with urinary incontinence after radical prostatectomy who were admitted to the hospital from June 2022 to June 2024 were selected and divided into control group and observation group, with 40 cases in each group. The control group was given routine nursing, and the observation group was given motivational psychological nursing combined with cognitive behavioral intervention on the basis of routine nursing. The Social Impact Scale (SIS) score, Exercise of Self-Care Agency Scale (ESCA) score and quality of life (QOL) score were compared between the two groups before and after intervention. Result: After intervention, the SIS score of the observation group was lower than that of the control group, the ESCA score was higher than that of the control group, and the QOL score was higher than that of the control group, and the differences were statistically significant (P<0.05). Conclusion: Motivational psychological nursing combined with cognitive behavioral intervention can effectively reduce the stigma, and improve the self-management ability and quality of life of patients with urinary incontinence after prostate cancer surgery.
  • Modern nursing
    Effect of Patient-care Shared Decision Making Combined with CBT Intervention in Patients After Coronary Angiography
    HUANG Yueli, YANG Congde, HUANG Yanan, LIU Lina, HUANG Shunhong
    2025, 23(19): 127-130. https://doi.org/10.14033/j.cnki.cfmr.2025.19.034
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: To explore the effect of patient-care shared decision making combined with cognitive behavioral therapy (CBT) in patients after coronary angiography. Method: From June 2023 to September 2024, 126 patients with coronary angiography admitted to the hospital were selected and divided into group A and group B by random number table method, with 63 cases each. Group A was given routine nursing intervention, group B was combined with CBT intervention on the basis of group A. The psychological status on the day after surgery, the 7 d of intervention [Hamilton Anxiety Scale (HAMA) score, Patient Health Questionnaire Depression Scale (PHQ-9) score], self-care ability [Self-care ability Measurement Scale (ESCA)] and the incidence of complications during the intervention were compared between the two groups. Result: On the 7th day of intervention, HAMA and PHQ-9 scores in both groups were lower than those on the day after surgery, and those in group B were lower than those in group A (P<0.05). On the 7th day of intervention, ESCA scores and total scores of both groups were higher than those of the postoperative day (P<0.05). During the intervention period, the complication rate of group B was lower than that of group A (P<0.05). Conclusion: The implementation of shared decision making and CBT intervention in patients after coronary angiography can significantly improve their psychological state and self-care ability, and the incidence of complications during the intervention is lower.
    • Experience
  • Experience
    Effect of Combined Application of Betahistine Mesylate and Manual Reduction on Vestibular Function in Patients with Benign Paroxysmal Positional Vertigo
    LIU He, SUN Zhongwu, MA Liang
    2025, 23(19): 131-134. https://doi.org/10.14033/j.cnki.cfmr.2025.19.035
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: To explore the effect of the combined application of betamethasone sulfonate and manual reduction on vestibular function in patients with benign paroxysmal positional vertigo (BPPV). Method: According to the inclusion/exclusion criteria, 108 BPPV patients were selected from Beijing Aerospace General Hospital from January 2023 to February 2024 were selected. Each patient was numbered and randomly divided into the control group and the observation group, with 54 patients in each group. The control group was treated with manual reduction, while the observation group was treated with betamethasone and manual reduction. The efficacy, vestibular function (VSI), balance function (BBS), Chinese version of dizziness handicap inventory (DHI), and recurrence rate between two groups were compared. Result: The total effective rate of the observation group was higher than that of the control group, and the difference was statistically significant (P<0.05). After treatment, compared with the control group, the observation group had lower VSI scores and higher BBS scores, with statistically significant differences (P<0.05). After treatment, compared with the control group, the observation group had significantly lower scores in the three dimensions of the DHI scale, and the difference was statistically significant (P<0.05). There was no statistically significant difference in the recurrence rate of BPPV between the two groups of patients after 3 months of treatment (P>0.05), but the observation group had a lower recurrence rate of BPPV after 6 months of treatment, and the difference was statistically significant (P<0.05). Conclusion: Simultaneous implement of manual reduction therapy for BPPV patients, combined with betamethasone sulfonate, is more conducive to improving vestibular function and balance ability, enhancing quality of life, and reducing the risk of recurrence
  • Experience
    Clinical Effect Analysis of Modified Gualou Xiebai Banxia Decoction Combined with Metoprolol Tartrate Tablets in the Treatment of Angina Pectoris in Coronary Heart Disease
    WANG Manqiang, LI Limei
    2025, 23(19): 135-138. https://doi.org/10.14033/j.cnki.cfmr.2025.19.036
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: To explore the efficacy and value of combined modified Gualou Xiebai Banxia decoction in the treatment of coronary heart disease angina pectoris. Method: 78 patients with coronary heart disease and angina pectoris in The Affiliated Rehabilitation Hospital of Fujian University of Traditional Chinese Medicine from May 2022 to April 2024 according to the inclusion and exclusion criteria. Different treatment plans were used as the grouping strategy. The control group (39 cases) was treated with metoprolol tartrate tablets, and the observation group (39 cases) was treated with modified Gualou Xiebai Banxia decoction. The clinical efficacy, angina attacks, TCM symptom scores, and related factor levels were compared between the two groups. Result: The total effective rate of the observation group was 92.31%, which was higher and the difference was statistically significant (P<0.05). After treatment, the observation group had less frequency and duration of angina attacks, and the difference was statistically significant (P<0.05). After treatment, the observation group had a lower TCM symptom score, and the difference was statistically significant (P<0.05). After treatment, the observation group had lower levels of matrix metalloproteinase-9 (MMP-9) and higher levels of matrix metalloproteinase inhibitor-1 (TIMP-1), with statistically significant difference (P<0.05). Conclusion: In the treatment of patients with coronary heart disease and angina pectoris, the combination of modified Gualou Xiebai Banxia decoction and metoprolol tartrate tablets can improve clinical efficacy, alleviate angina attacks, and improve traditional Chinese medicine syndrome scores and MMP-9, TIMP-1 levels. The curative effect is good.
  • Experience
    Influence of LCP Combined with Minimally Invasive Plate Osteotomy Technique on the Therapeutic Effect and Complications of Patients with Traumatic Fractures of the Extremities
    QIN Guangyang, GUO Xiaoxiang, WEI Wanmian, WEI Yongping, WEI Baotang, WEI Xiangao, TAN Xingyue, WEI Yong’an
    2025, 23(19): 138-142. https://doi.org/10.14033/j.cnki.cfmr.2025.19.037
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: To explore the influence of locking compression plate (LCP) combined with minimally invasive plate osteosynthesis technique on the therapeutic effect and complications of patients with traumatic fractures of the extremities. Method: A total of 78 patients with traumatic fractures of the extremities admitted to the First People's Hospital of Hechi City, Guangxi from January 2022 to December 2023 were randomly divided into control group (n=39) and observation group (n=39) using a random number table. The control group was treated with open reduction and internal fixation, while the observation group was treated with LCP combined with minimally invasive plate osteosynthesis. The treatment effects and complication rates were compared between the two groups. Result: Compared with the control group, the observation group had shorter operation time, hospital stay, callus formation and healing time; lower levels of serum enzymes such as lactate dehydrogenase (LDH), creatine kinase (CK), and creatine kinase-MB (CK-MB) at 1 week postoperatively; longer prothrombin time (PT) and thrombin time (TT), and lower fibrinogen (FIB) levels at 1 week postoperatively; lower levels of inflammatory response indicators such as interleukin-6 (IL-6) and high-sensitivity C-reactive protein (hs-CRP) at 1 week postoperatively; higher levels of superoxide dismutase (SOD) and lower levels of malondialdehyde (MDA) after 1 week postoperatively; and a lower total incidence of postoperative complications, with statistically significant differences (P<0.05). Conclusion: The application of LCP combined with minimally invasive plate osteosynthesis in the treatment of patients with traumatic fractures of the extremities can promote rapid healing of the fracture site, improve serum enzyme and coagulation function, reduce the body's inflammatory and stress responses, and effectively prevent the occurrence of postoperative complications..
  • Experience
    Curative Effect of Wenshen Jianpi Qinghua Decoction in Patients with Chronic Renal Failure of Spleen-kidney Qi Deficiency Type
    SHEN Kangfei, ZHOU Yilie
    2025, 23(19): 143-147. https://doi.org/10.14033/j.cnki.cfmr.2025.19.038
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: To explore the curative effect of Wenshen Jianpi Qinghua Decoction in patients with chronic renal failure (CRF). Method: 100 patients with CRF treated in Suzhou Wujiang District Hospital of Traditional Chinese Medicine from May 2023 to July 2024 were enrolled. According to random number table method, they were divided into routine group (n=50, compound α-ketoacid tablets) and study group (n=50, Wenshen Jianpi Qinghua Decoction on basis of routine group). The clinical curative effect, scores of TCM symptoms, renal function indexes [serum creatinine (Scr), blood urea nitrogen (BUN) and uric acid (UA)], oxidative stress level [superoxide dismutase (SOD), malondialdehyde (MDA), glutathione peroxidase (GSH-Px)] and adverse reactions were compared between the two groups after treatment. Result: The total response rate of study group was higher than routine group (P<0.05). After treatment, scores of TCM syndromes were decreased in both groups, which were lower in study group than routine group (P<0.05). After treatment, Scr, BUN and UA decreased in both groups, which were lower in study group than routine group (P<0.05). After treatment, SOD and GSH-Px increased in both groups, which were higher in study group than routine group, while MDA was decreased, which was lower in study group than routine group (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion: Adjuvant therapy with Wenshen Jianpi Qinghua Decoction has significant curative effect in CRF patients, which is beneficial to alleviate clinical symptoms, improve renal function and reduce oxidative stress level, with certain safety.
  • Experience
    Effect of Pingwei San Combined with Shenling Baizhu San on Traditional Chinese Medicine Syndrome Score and Gastrointestinal Motility in Patients with Diarrhea Predominant Irritable Bowel Syndrome of Spleen and Stomach Weakness Syndrome
    LIU Zongyan, LIU Xiaoyan
    2025, 23(19): 147-150. https://doi.org/10.14033/j.cnki.cfmr.2025.19.039
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: To investigate the effects of Pingwei San combined with Shenling Baizhu San on the TCM syndrome score and gastrointestinal motility in patients with Irritable Bowel Syndrome with Diarrhea (IBS-D) due to spleen and stomach weakness. Method: A total of 92 patients with IBS-D admitted to Chengguan District People's Hospital in Lanzhou City from August 2021 to August 2024 were selected and divided into control group (46 cases, treated with Trimebutine Maleate Capsules+Bifidobacterium Triple Active Bacteria Enteric Coating Capsules) and observation group (46 cases, treated with Pingwei Powder and Shenling Baizhu Powder). After 4 weeks of treatment, the clinical efficacy of the two groups was compared, including traditional Chinese medicine syndrome scores, gastrointestinal motility indicators (Motilin, MTL), substance P (SP), and adverse reactions before and after treatment. Result: After treatment, the effective rate of the observation group was higher than that of the control group, and the difference was statistically significant (P<0.05). The scores of various traditional Chinese medicine syndromes in the observation group were lower than those in the control group, and the difference was statistically significant (P<0.05). The MTL of the observation group was lower than that of the control group, and the SP was higher than that of the control group, with statistically significant difference (P<0.05). The difference in adverse reaction rates between the two groups was statistically significant (P=0.011). Conclusion: The treatment of IBS-D patients with spleen and stomach weakness with Pingwei San combined with Shenling Baizhu San can effectively improve their traditional Chinese medicine symptoms and gastrointestinal motility levels, with significant therapeutic effects and high safety.
  • Experience
    Effect of Oral Sucrose Combined with Non Nutritive Sucking on Neonatal Operational Pain
    LU Rongrong, HAO Jiali, CAI Juan, ZHAO Shengnan
    2025, 23(19): 151-154. https://doi.org/10.14033/j.cnki.cfmr.2025.19.040
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: To explore the effect of oral sucrose combined with non nutritional sucking on painful procedures in newborns in NICU wards. Method: 120 newborns hospitalized in The First Affiliated Hospital of Bengbu Medical University from January to December 2023 were selected as the study subjects, and randomly divided into experimental group (n=60) and control group (n=60). During hospitalization, these 120 newborns underwent painful procedures such as venipuncture. The experimental group received oral sucrose combined with non nutritive suction before puncture, while the control group received routine nursing measures such as comfort. The physiological indicators, facial coding system,and pain rating scale of two groups were compared. Result: The experimental group not only had better indicators such as heart rate, respiration, and oxygen saturation than the control group, but also had lower facial coding system and pain scale scores than the control group, with statistically significant differences (P<0.05). Conclusion: For newborns who require intravenous puncture, the intervention of oral sucrose combined with non nutritive suction can significantly improve their pain indicators, and reduce the negative impact of pain.
  • Experience
    Effect of Thoracic Paravertebral Block Combined with General Anesthesia in Radical Lung Cancer Surgery
    LIU Guangjie, LIU Tao
    2025, 23(19): 155-158. https://doi.org/10.14033/j.cnki.cfmr.2025.19.041
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: To investigate the effect of thoracic paravertebral block (TPVB) combined with general anesthesia in radical lung cancer surgery. Method: A total of 180 patients who underwent radical lung cancer surgery in Zhangqiu District People's Hospital, from March 2022 to November 2024, were enrolled as research subjects. They were randomly divided into two groups using the envelope draw method: the general anesthesia group (n=90) and the combined anesthesia group (n=90). The general anesthesia group received general anesthesia, while the combined anesthesia group received TPVB combined with general anesthesia. The perioperative indicators, heart rate (HR), mean arterial pressure (MAP) at different time points, and cognitive function were compared between the two groups. Result: The postoperative anesthesia care unit (PACU) stay duration and the number of patient-controlled intravenous analgesia (PCIA) presses in the combined group were significantly lower than those in the general anesthesia group (P<0.05). 5 minutes after the start of surgery (T1) and at the end of surgery (T2), the heart rate (HR) and mean arterial pressure (MAP) in the combined group were significantly lower than those in the general anesthesia group (P<0.05). 24 hours after operation, the level of S100β, a central nervous system-specific protein in the combined group was significantly lower than that in the general anesthesia group, while the levels of brain-derived neurotrophic factor (BDNF) and the Mini-Mental State Examination (MMSE) scores were significantly higher (P<0.05). Conclusion: TPVB combined with general anesthesia shows significant effects in radical lung cancer surgery.
    • Synthetic medicine
  • Synthetic medicine
    Application of Family Empowerment and Self-efficacy Theory in Treatment Compliance of Patients with Diabetes Retinopathy
    BAN Fengjiao, HE Jie, TANG Jinmei, LONG Yanchun, HE Qianshang
    2025, 23(19): 159-162. https://doi.org/10.14033/j.cnki.cfmr.2025.19.042
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: To explore the application effect of family empowerment and self-efficacy theory in the treatment compliance of patients with diabetes retinopathy. Method: 80 patients with diabetes retinopathy admitted to Baise People's Hospital from January 2023 to June 2024 were randomly divided into control group (40 cases) and study group (40 cases) with conventional intervention based on family empowerment and self-efficacy theory. Two sets of biochemical indicators, self-efficacy, and treatment compliance were compared. Result: After the intervention, both groups showed a decreasing trend in fasting blood glucose and 2-hour postprandial blood glucose, and an increasing trend in self-efficacy score, with the study group showing a more significant trend (P<0.05). The compliance of the research group was significantly higher than that of the control group (P<0.05). Conclusion: The application of family empowerment and self-efficacy theory in patients with diabetes retinopathy can promote patients to control blood sugar, and improve self-efficacy and treatment compliance.
  • Synthetic medicine
    Study on the Application of Cognitive Stimulation Training Combined with Medical Community Intervention in Patients with Cognitive Dysfunction and its Influence on Quality of Life and Cognitive Level
    LIN Wenjing
    2025, 23(19): 163-166. https://doi.org/10.14033/j.cnki.cfmr.2025.19.043
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: To explore the application effect of cognitive stimulation training combined with medical community intervention in patients with cognitive dysfunction and its influence on quality of life and cognitive level. Method: 120 patients with cognitive dysfunction were selected from May 2022 to February 2024. They were divided into two groups by envelope method, with 60 cases in each group. The control group received routine nursing, and the observation group combined with the intervention of the medical community and cognitive stimulation training. The effects of the two groups were evaluated after 4 weeks of intervention. The quality of life, cognitive level, drinking water test, fall score, compliance and satisfaction were compared between the two groups. Result: The quality of life of two groups was improved after intervention. The life quality of observation group was higher than that of control group (P<0.05). The MMSE score of observation group was higher than that of control group after intervention (P<0.05). The scores of fall in drinking water test were lower than those in control group (P<0.05). The compliance and satisfaction of the observation group after intervention were higher than those of the control group (P<0.05). Conclusion: Cognitive stimulation training combined with medical community intervention has good effect in patients with cognitive dysfunction, which can improve the daily living standard, promote the cognitive level of patients, and reduce the fall score. The patient compliance and satisfaction are high.
  • Synthetic medicine
    Application of Precision Nutrition Support Combined with Active Psychological Interventions in Patients with Esophageal Cancer
    TENG Hong, WANG Qifang
    2025, 23(19): 167-171. https://doi.org/10.14033/j.cnki.cfmr.2025.19.044
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: To investigate the impact of precision nutrition support and active psychological interventions on psychological health, fatigue and quality of life in patients with esophageal cancer. Method: 92 patients with esophageal cancer admitted to Funing County People's Hospital from March 2022 and February 2024 were randomly assigned to conventional group or combined group using a random number table, with 46 patients in each group. The conventional group received standard care, while the combined group received precision nutrition support combined with active psychological intervention. The psychological health status, fatigue levels, quality of life nutritional indices and nursing satisfaction before and after intervention were compared between the two groups. Result: After the intervention, the combined group showed significantly higher levels of total protein (TP), albumin (ALB) and prealbumin (PA) compared to the routine care group, with statistically significant differences (P<0.05). Additionally, the combined group had lower scores on the Distress Thermometer (DT) and higher scores on the Connor-Davidson Resilience Scale (CD-RISC) compared to the routine group after the intervention, with statistically significant differences (P<0.05). Furthermore, the combined group showed significantly lower levels of physical fatigue, emotional fatigue, cognitive fatigue and overall scores on the Chinese version of the Cancer Fatigue Scale (CFS) compared to the routine group after the intervention, with statistically significant differences (P<0.05). After the intervention, the combined group also had significantly lower scores for swallowing difficulties, eating, pain, and reflux compared to the routine care group, with statistically significant differences (P<0.05). The nursing satisfaction rate in the combined group was 89.13%, which was significantly higher than the 71.74% in the routine care group, with statistically significant difference (P<0.05). Conclusion: Fine nutritional support combined with positive psychological intervention can significantly improve the psychological state and quality of life of esophageal cancer patients, while enhance their nutritional status and nursing satisfaction.
  • Synthetic medicine
    A Case-control Study on the Relationship Between Traditional Chinese Medicine Constitution Types and Bone Metabolism Indicators in Middle-aged and ELderly Patients with Osteoporosis Undergoing Physical Examination in the Community
    LIU Xiaoshuang
    2025, 23(19): 172-175. https://doi.org/10.14033/j.cnki.cfmr.2025.19.045
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: To comprehensively analyze the constitution classification of elderly osteoporosis physical examination subjects in the community and its interaction with bone metabolism indicators. Method: 50 middle-aged and elderly patients with osteoporosis who underwent physical examinations in The Second Affiliated Hospital of Fujian University of Traditional Chinese Medicine from January 2023 to June 2024 were selected as the case group, and another 50 healthy middle-aged and elderly patients who underwent physical examinations during the same period were selected as the control group. General information of patients was collected on site, standardized traditional Chinese medicine constitution identification scales for detailed constitution classification was conducted, and bone metabolism indicators (N-terminal osteocalcin, alkaline phosphatase, β-collagen special sequence) were detected. Result: The proportions of qi deficiency constitution, Yang deficiency constitution and phlegm-dampness constitution in the case group were significantly higher than those in the control group, and the difference was statistically significant (P<0.05). Among patients aged 50 to 60, the proportions of qi deficiency constitution and phlegm-dampness constitution were the highest. Among patients aged 61 to 70, the proportions of qi deficiency constitution, Yang deficiency constitution and phlegm-dampness constitution were relatively high. Among patients aged 71 to 80, the proportion of those with Yang deficiency was the highest. The levels of N-terminal osteocalcin in qi deficiency constitution, Yang deficiency constitution and phlegm-dampness constitution were significantly lower than those in other constitution types, and the difference was statistically significant (P<0.05). The levels of alkaline phosphatase and special sequences of β-collagen were significantly higher than those in other constitution types, and the difference was statistically significant (P<0.05). Conclusion: The traditional Chinese medicine constitution types of middle-aged and elderly osteoporosis patients undergoing physical examination in the community are mainly qi deficiency, Yang deficiency, and phlegm dampness, which can change with age, and have significant correlation with bone metabolism.
    • Review
  • Review
    Research Progress on the Characteristics of Intracranial Atherosclerotic Plaques in Diabetic Patients Based on High-resolution Magnetic Resonance Vessel Wall Imaging Technology
    HU Junwei, SANG Junzhi, HUANG Xin
    2025, 23(19): 176-179. https://doi.org/10.14033/j.cnki.cfmr.2025.19.046
    Abstract ( ) PDF ( ) Knowledge map Save
    Diabetes is an important risk factor for atherosclerosis and stroke, and it is an important factor contributing to the death and poor prognosis of patients with intracranial ischemic stroke. Early diagnosis, formulation of treatment plans, and prognosis evaluation are crucial for preventing stroke, improving prognosis, and reducing mortality in diabetic patients. High-resolution magnetic resonance vessel wall imaging technology (HRMR-VWI) can directly present the situation of the intracranial arterial wall in diabetic patients with ischemic stroke and provide qualitative and quantitative assessment of plaques, which is of great significance in providing diagnostic basis, risk stratification, etiological analysis, formulation of treatment plans, and prognosis evaluation for patients. The study reviews the HRMR-VWI technology and its application in analyzing the characteristics of intracranial plaques in diabetic patients.
  • Review
    Research Progress in the Treatment of Gastroesophageal Reflux Disease
    LI Zongxuan
    2025, 23(19): 180-184. https://doi.org/10.14033/j.cnki.cfmr.2025.19.047
    Abstract ( ) PDF ( ) Knowledge map Save
    Gastroesophageal reflux disease (GERD) is a common chronic digestive disorder characterized by symptoms such as reflux, heartburn, bloating, belching, and chest pain, which can lead to severe complications like esophageal adenocarcinoma. With the ongoing social and economic development and lifestyle changes, the prevalence of GERD continues to rise, particularly in Asian countries. Although proton pump inhibitors (PPIs) are considered as the first-line treatment, monotherapy presents limitations, such as incomplete symptom relief and long-term safety concerns. Therefore, recent treatment strategies have gradually shifted towards diversification and personalization. The study summarizes the latest advances in GERD treatment, including the use of acid-suppressing agents, prokinetics, mucosal protectants, reflux inhibitors, and neuromodulators, as well as non-pharmacological interventions such as endoscopic and surgical therapies. Additionally, the treatment characteristics for special populations, including children, the elderly, and pregnant women, are discussed. By optimizing combination therapy and individualized approaches, the clinical outcomes for GERD patients and their quality of life are expected to improve further.

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