2025 Volume 23 Issue 9 Published: 25 March 2025
  

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  • Article
    DENG Haiyan, CHEN Wenlan, MA Lianying
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    Objective: To investigate the effect of pre-labor hyperbaric oxygen (HBO) combined with labetalol in the treatment of hypertensive patients during pregnancy. Method: A total of 101 patients with pregnancy-induced hypertension admitted to Wuyishan City Maternal and Child Health Hospital from January 2020 to January 2024 were selected as the study objects, and randomly divided into control group (n=49) and observation group (n=52). The control group was treated with labetalol, and the observation group was treated with HBO. Blood pressure control level, uterine arterial hemodynamics [pulse index (PI), resistance index (RI), systolic peak velocity/diastolic end velocity (S/D)] and incidence of adverse pregnancy outcomes were compared between the two groups. Result: After treatment, diastolic blood pressure (DBP), systolic blood pressure (SBP), PI, RI and S/D in the observation group were lower than those in the control group, and the differences were statistically significant (P<0.05). The incidence of adverse delivery outcomes and adverse fetal outcomes in the observation group were lower than those in the control group, with statistical significance (P<0.05). Conclusion: HBO combined with labetalol in the treatment of gestational hypertension before delivery can effectively control the blood pressure level of patients, promote hemodynamic recovery, and have good safety.
  • Article
    CHEN Na
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    Objective: To analyze the effect of immunotherapy on immune function and symptoms of children with adenovirus pneumonia. Method: A total of A total of 80 children with adenovirus pneumonia admitted to Xianning First People's Hospital of from January 2022 to December 2023 were selected as the study objects and divided into two groups according to the principle of random single blindness, with 40 cases in each group. The control group only received cedovir treatment, while the study group was treated with gamma globulin on the basis of the control group, and the immune function and symptom improvement of the two groups were compared. Result: Compared with the control group, the total effective rate of the study group was significantly higher, and the duration of cough, fever, moist rales disappearance and hospital stay were significantly shorter, and the difference was statistically significant (P<0.05). Compared with the control group after treatment, the levels of CD3+, CD4+, CD4+/CD8+, immunoglobulin G (IgG) and immunoglobulin A (IgA) in the study group were significantly higher, but the levels of CD8+, immunoglobulin M (IgM), Clara cell secreted protein (CCSP), interleukin-1 (IL-1), interleukin-2 (IL-2) and tumor necrosis factor-α (TNF-α) were significantly lower, the difference was statistically significant (P<0.05). There was no significant difference in adverse reactions between the two groups (P>0.05). Conclusion: Immunotherapy in children with adenovirus pneumonia can significantly improve their immune function, effectively reduce their symptoms and inflammatory expression, and reduce adverse reactions, which can promote early recovery of children.
  • Article
    YI Tingwei, YANG Shengwen, LI Jingjing
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    Objective: To analyze the effects of transcranial direct current stimulation on upper limb motor function recovery and prognosis in patients with stroke-induced upper limb motor impairment. Method: A total of 86 patients with upper limb motor dysfunction after stroke admitted to Liangzhou Hospital of Wuwei City from March 2019 to May 2023 were selected as the study objects. According to the method of computer random number table, the patients were divided into control group and study group, with 43 cases in each group. The control group received conventional rehabilitation treatment, while the experimental group received transcranial direct current stimulation technology. The effect of upper limb motor function recovery, hand function level, somatosensory evoked potential and EMG level of the affected upper limb were compared between the two groups. Result: After treatment, the scores of Fugl-Meyer Assessment Upper Extremity Scale (FMA-UE), Simple Test For Evaluating Hand Function (STEF) and Carroll Upper Extremity Function Test (UEFT) in experimental group were higher than those in control group, and the differences were statistically significant (P<0.05). The Wolf Motor Function Test Scale (WMFT) score in experimental group was higher than that in control group, and the difference was statistically significant (P<0.05). The amplitude of N20 in the affected upper limb of the experimental group was higher than that in the control group, and the incubation period was shorter, with statistical significance (P<0.05). The integrated electromyography (iEMG) of the forearm extensor muscle group, deltoid muscle and triceps muscle of the affected side of the experimental group were higher than those of the control group, and the difference was statistically significant (P<0.05). Conclusion: In the rehabilitation treatment of stroke patients with upper limb motor dysfunction, transcranial direct current stimulation can improve the recovery effect of upper limb motor function, improve hand function level, and promote the recovery of somatosensory evoked potential and EMG level of the affected upper limb.
  • Article
    LI Zhibin, GUO Min, YANG Jianchang
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    Objective: To analyze and logistic regression analysis of infection and risk factors after prostate biopsy. Method: A total of 234 patients with transrectal prostate biopsy admitted to People's Hospital of Dali Bai Autonomous Prefecture from November 2019 to November 2023 were selected as the study objects. The patients were divided into using routine antibiotic prophylaxis group (n=123) and no routine prophylaxis group (n=111) according to whether they used prophylactic antibiotics. The incidence of infection in the two groups 2 weeks after surgery was analyzed by logistic regression. The risk factors of infection after prostate biopsy were analyzed. Result: The infection rate in the group using prophylactic antibiotics was significantly lower than that in the group without prophylactic antibiotics, and the difference was statistically significant (P<0.05). There were significant differences in body mass index (BMI), diabetes mellitus, catheter indentation before surgery, puncture inflammation and tumor bone metastasis between the two groups (P<0.05). Logistic regression analysis showed that diabetes mellitus, catheter indentation before surgery, and tumor bone metastasis were the risk factors for infection after transrectal prostate biopsy, and the difference was statistically significant (P<0.05). Conclusion: Preoperative prophylactic use of antibiotics can reduce the risk of infection after transrectal prostate biopsy to a certain extent. Diabetes mellitus, catheter indwelling before surgery, and tumor bone metastasis are risk factors for infection after transrectal prostate biopsy.
  • Article
    ZHANG Jie, LIU Chengying
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    Objective: To explore the biochemical detection of recombinant histone deacetylase 2 (HDAC2) and Interleukin-8 (IL-8) and Tumor necrosis factor-α (TNF-α) in patients with chronic obstructive pulmonary disease, and analyze the relationship between the level of various indicators and the disease, as well as the evaluation value of the treatment effect of the disease. Method: 165 patients with chronic obstructive pulmonary disease treated in Jiangyin People's Hospital from January 2022 to May 2024 were selected as the study group. Another 150 healthy adults were selected as control group. The levels of HDAC2, IL-8 and TNF-α were compared between the two groups, and the levels of HDAC2, IL-8 and TNF-α were compared between the attack stage and the stable stage of chronic obstructive pulmonary disease. The levels of HDAC2, IL-8 and TNF-α were compared before and after treatment. Result: The levels of HDAC2 in the study group were lower than those in the control group, and the levels of IL-8 and TNF-α were significantly higher than those in the control group (P<0.05). The levels of HDAC2 in patients with COPD were lower than those in control group, and the levels of IL-8 and TNF-α were higher than those in control group (P<0.05). After treatment, the HDAC2 detection level in the study group was higher than that before treatment, and the IL-8 and TNF-α levels were lower than that before treatment (P<0.05). Conclusion: The detection levels of HDAC2, IL-8 and TNF-α can be used as diagnostic basis for chronic obstructive pulmonary disease, and can evaluate the severity of the disease and provide reference for the treatment of the disease.
  • Article
    DENG Ya, YANG Xiaoming, LAI Hanguang, LIN Xianniang
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    Objective: To explore the predictive value of C-reactive protein combined with eosinophils for adverse transfusion reactions. Method: Clinical data of 160 blood transfusion patients admitted to the Second Hospital of Sanming from January 2020 to December 2023 was retrospectively analyzed, and divided into observation group (adverse blood transfusion reaction accurred, n=88) and control group (no adverse blood transfusion reaction, n=72) according to whether there was adverse blood transfusion reaction. The changes and correlation of CRP and eosinophils before and after transfusion were analyzed in the two groups, and the value of CRP combined with eosinophils in predicting transfusion adverse reactions was evaluated. Result: The difference of CRP and eosinophils in observation group were higher than those in control group, and the difference was statistically significant (P<0.05). Multifactor analysis showed that CRP difference and eosinophil difference were risk factors for adverse blood transfusion reactions (P<0.05). Receiver operating characteristic (ROC) showed that the sensitivity and specificity of the combined test for the diagnosis of adverse blood transfusion reactions were 0.918 and 0.817, respectively, and the area under the curve (AUC) was 0.906, which was significantly higher than that predicted by alone, and the difference was statistically significant (P<0.05). Conclusion: The difference of CRP and eosinophils before and after transfusion can predict the occurrence of adverse reactions after transfusion, and the combination of CRP and eosinophils is more valuable.
  • Article
    ZHAN Yan
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    Objective: To explore the clinical efficacy of bevacizumab in the treatment of platinum resistant recurrent advanced ovarian cancer. Method: A total of 80 patients with platinum-resistant recurrent advanced ovarian cancer treated in People's Hospital of Luotian County from December 2021 to December 2023 were selected as study objects, and divided into study group (n=40) and control group (n=40) according to random number table method. The control group was given paclitaxel chemotherapy, and the study group was given bevacizumab combined with paclitaxel chemotherapy. The clinical efficacy, serum indexes, quality of life and adverse reactions were compared between the two groups. Result: The disease control rate (DCR) and objective response rate (ORR) of the study group were higher than those of the control group, and the difference was statistically significant (P<0.05). After treatment, the levels of Human Epidrdymis protein 4 (HE4), carcinoembryonic antigen (CEA) and vascular endothelial growth factor (VEGF) in two groups were decreased, and the levels in the study group were lower than those in the control group, and the difference was statistically significant (P<0.05). After treatment, the Karnofsky Performance Status Scale (KPS) score of the two groups increased, and the study group was higher than the control group, and the difference was statistically significant (P<0.05). The incidence of adverse reactions in study group was lower than that in control group, and the difference was not statistically significant (P>0.05). Conclusion: Bevacizumab is used in the treatment of platinum-resistant recurrent advanced ovarian cancer, which can improve clinical efficacy, promote quality of life, and have high safety. Its mechanism of action may be related to inhibiting the expression of tumor markers and improving VEGF levels.
  • Clinical practice
  • Clinical practice
    CHEN Man, ZHAO Xiaohui, XIE Saihua
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    Objective: To discuss the efficacy of atorvastatin and ezetimibe in patients with coronary heart disease (CHD). Method: A total of 60 CHD patients admitted to Guilin Hospital of Traditional Chinese Medicine from December 2022 to December 2023 were selected as the study objects and divided into control group (n=30, atorvastatin oral treatment) and observation group (n=30, atorvastatin combined with Ezetimibe oral treatment) by random number table method, and the specific treatment effects of the two groups were compared. Result: The effective rate of observation group was was higher than that of control group, and the difference was statistically significant (P<0.05). After treatment, the indexes of left ventricular end-systolic diameter (LVESD), left ventricular end-diastolic diameter (LVEDD) and amino-terminal brain lipeptide precursor (NT-proBNP) in observation group were lower than those in control group, and left ventricular ejection fraction (LVEF) was higher than that in control group, with statistical significance (P<0.05). The incidence of headache, abdominal discomfort, insomnia, nausea and other adverse reactions in the observation group was higher than that in the control group, there was no statistical significance (P>0.05). Conclusion: Atorvastatin combined with ezetimibe is effective in the treatment of CHD, which is better than atorvastatin monotherapy, and the heart function of patients is effectively improved with guaranteed safety.
  • Clinical practice
    GUO Pingping, QIU Canming
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    Objective: To investigate the efficacy of nebulized inhalation of terbutaline combined with beclomethasone in the treatment of elderly patients with chronic obstructive pulmonary disease. Method: A total of 82 elderly patients with chronic obstructive pulmonary disease admitted to the Second Hospital of Longyan, from January 2021 to January 2024 were selected as the study objects, and were divided into study group and control group according to the lottery method, with 41 cases in each group. The study group was given terbutaline combined with beclomethasone atomized inhalation therapy, while the control group was given terbutaline therapy. The clinical efficacy, symptom remission time, lung function, blood gas index and the occurrence of adverse reactions were compared between the two groups. Result: The total effective rate of the study group was higher than that of the control group, and the difference was statistically significant (P<0.05). The resolution time of cough, wheezing and dyspnea in the study group was shorter than that in the control group, and the difference was statistically significant (P<0.05). After treatment, forced vital capacity (FCV) and forced expiratory volume in the first second (FEV1) of both groups were increased, and the study group was higher than the control group, and the difference was statistically significant (P<0.05). After treatment, the arterial partial pressure of oxygen (PaO2) and oxygen saturation (SpO2) were increased and the arterial partial pressure of carbon dioxide (PaCO2) was decreased in both groups, and the PaO2 and SpO2 in the study group were higher than those in the control group and the PaCO2 was lower than those in the control group, with statistical significance (P<0.05). There was statistical significance in the incidence of adverse reactions between the two groups (P<0.05). Conclusion: The application of terbutaline combined with beclomethasone atomized inhalation in the treatment of chronic obstructive pulmonary disease in the elderly has a good effect, can improve lung function and blood gas indexes, promote symptom relief, and has a certain safety.
  • Clinical practice
    FAN Menghao
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    Objective: To explore the effects of blood flow restriction therapy combined with Mulligan dynamic joint mobilization on pain, exercise fear, and functional recovery in patients with knee osteoarthritis. Method: A total of 120 patients with knee osteoarthritis who were treated in Shanxi Provincial Integrated TCM and WM Hospital from January 2022 to June 2023 were selected as the study objects, and were divided into combination group, blood flow restriction therapy group and dynamic joint loosening group according to random number table method, with 40 cases in each group. The dynamic joint loosening group received Mulligan dynamic joint loosening, the blood flow restriction therapy group received blood flow restriction training, and the combined group received both dynamic joint loosening and blood flow restriction training for a total of 8 weeks. Visual Analog Scale (VAS), Tampa Scale for Kinesiophobia (TSK), Western Ontario and McMaster University Rating Scale (WOMAC), Berg Balance Scale (BBS), standing up and Sitting test (TUGT) and 10-meter walking test were compared before and after the intervention. Result: After intervention, VAS score, TSK score, WOMAC score, TUGT score and 10-meter walking test were all decreased in the three groups, and BBS score was increased, and the difference was statistically significant (P<0.05). After intervention, compared with the blood flow restriction group and dynamic joint loosening group, VAS score, TSK score, WOMAC score, TUGT score and 10-meter walking test were lower in the combined group. And BBS score was higher, with statistical significance (P<0.05). Conclusion: The combination of flow restriction therapy and Mulligan dynamic joint loosening or single method can improve pain, exercise fear and functional recovery in patients with knee osteoarthritis, but the combined effect is more obvious.
  • Clinical practice
    JIANG Yan, WANG Xiaoqin
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    Objective: To explore the clinical effect of Yinhu Ganmao powder patch on acute upper respiratory tract infection in children. Method: Sixty children with acute upper respiratory tract infection admitted to the Affiliated Hospital of Zunyi Medical University from May 2022 to November 2022 were selected as the study objects. The patients were divided into observation group and control group by systematic randomization, with 30 cases in each group. The control group received conventional oral treatment, and the observation group received Yinhu Ganmao powder patch on the basis of conventional treatment. The main disease score, secondary disease score, symptom change time, clinical efficacy, symptom score and incidence of adverse reactions were compared between the two groups. Result: After treatment, the disappearance time of clinical symptoms in the observation group was shorter than that in the control group, and the difference was statistically significant (P<0.05). The effective rate of treatment in observation group was higher than that in control group, and the difference was statistically significant (P<0.05). Symptom score of observation group was lower than control group, and the difference was statistically significant (P<0.05). The incidence of adverse events in observation group was lower than that in control group, and the difference was statistically significant (P<0.05). Conclusion: The use of Yinhu Ganmao powder patch in the treatment of acute upper respiratory tract infection in children can improve the clinical symptoms, shorten the course of the disease, reduce the symptom score, and no adverse reactions.
  • Clinical practice
    TIAN Xiayang, LIN Peng, CAI Qiyao, DING Yating, LAI Weihong, HONG Tiansheng
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    Objective: To investigate the efficacy of intramuscular taping therapy on early functional recovery after patellar fracture surgery. Method: 60 with patellar fracture admitted to Jinjiang Hospital from July 2023 to April 2024 were selected as study objects and divided into control group (routine rehabilitation training, 30 cases) and observation group (routine rehabilitation training combined with intramuscular bandage, 30 cases) according to random number table method. The function of the patients was evaluated before treatment, 7 days and 21 d, respectively. To analyze the effect of intramuscular taping therapy on early functional recovery after patellar fracture. Result: After treatment, the observation group was superior to the control group in knee function (HSS score), Lysholm knee score scale(LKSS), Visual Analogue Scale (VAS), quadriceps recruitment and activation, and the difference was statistically significant (P<0.05). Conclusion: Intramuscular taping therapy has a good effect on early functional recovery after patellar fracture surgery.
  • Clinical practice
    XIE Lifei, JIANG Kai
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    Objective: To study the effect of totally laparoscopic distal gastrectomy (TLDG) and laparoscopic assisted distal gastrectomy (TLDG) in elderly patients with gastric cancer. Method: A total of 60 patients with gastric cancer admitted to the Affiliated Hospital of Jiangnan University from January 2022 to January 2024 were selected for this study. They were randomly divided into full cavity mirror group (n=30) and auxiliary group (n=30) by computer numbering method. TLDG was used in the endoscopic group and LADG was used in the auxiliary group. The results of the two groups were compared (evaluation indicators included surgical indicators, inflammatory factors, immune indicators, complications). Result: The intraoperative blood loss in the total endoscopy group was less than that in the auxiliary group, and the postoperative exhaust time, feeding time and hospitalization days were shorter than those in the auxiliary group, with statistical significance (P<0.05). The levels of serum inflammatory factors in 2 groups were higher than before 3 days after surgery, but the total endoscopy group was lower than the auxiliary group, and the difference was statistically significant (P<0.05). The levels of all immune function indexes in the two groups were lower than those before surgery, but the total endoscopy group was higher than the auxiliary group, with statistical significance (P<0.05). Conclusion: Compared with LADG, the application of TLDG in elderly patients with gastric cancer has a better effect, which can promote the early recovery of patients, reduce the degree of inflammation and immune function decline caused by surgery, and will not increase the risk of complications.
  • Clinical practice
    ZHANG Chengrong, ZHONG Zhengping
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    Objective: To investigate the effects of doxofylline combined with Budesonide on symptoms and pulmonary function in patients with asthma. Method: A total of 104 asthma patients admitted to Zunyi Infectious Disease Hospital from April 2022 to April 2024 were selected as the study objects and divided into a control group and an observation group according to the random number table. The control group (52 cases) were treated with budesonide, while the observation group (52 cases) was treated with doxofylline and budesonide. The changes of small airway response, lung function, adverse reactions and clinical efficacy of the two groups were observed. Result: The maximum respiraory airflow at each level of vital capacity in the observation group were significantly higher than those in the control group, with statistical significance (P<0.05). The levels of Forced Vital Capacity (FVC), Percentage of Predicated Value of Forced Expiratory Volume in One Second (FEV1%), Percentage of Predicted Maximal Voluntary Ventilation (MVV%) and Peak Expiratory Flow (PEF) were significantly higher than those of control group, with statistical significance (P<0.05). There was no statistical significance in the occurrence of nausea and vomiting, dysphagia, abdominal pain and tachycardia between the two groups (P>0.05). And the curative effect of the observation group was significantly higher than that of the control group, with statistical significance (P<0.05). Conclusion: Doxofylline and budesonide combined therapy can relieve inflammation, improve small airway function and lung function, and reduce oxidative stress in patients with asthma. The efficacy is safe and reliable.
  • Clinical practice
    WANG Yajian
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    Objective: To analyze the clinical efficacy and impact on renal function of the combined use of cyclophosphamide and glucocorticoids in the treatment of nephrotic syndrome (NS) patients. Method: A total of 86 patients with NS treated in Liupanshui People's Hospital from July 2020 to August 2024 were selected as the study objects. They were divided into control group and observation group by stratified drawing method, with 43 cases in each group. The control group was treated with glucocorticoid, and the observation group was treated with cyclophosphamide combined with glucocorticoid. The therapeutic effect, renal function index, blood lipid index, toxicity and side effects were compared between the two groups. Result: The total clinical effective rate of the observation group was better than that of the control group, and the difference was statistically significant (P<0.05). After treatment, compared with control group, serum albumin (ALB) content and serum creatinine level in observation group were higher, blood urea nitrogen (BUN) concentration and 24 h urinary protein quantitative level were lower, and the differences were statistically significant (P<0.05). After treatment, the levels of triglyceride (TG), total cholesterol (TC)and low density lipoprotein cholesterol (LDL-C) in the observation group were lower than those in the control group, and the difference was statistically significant (P<0.05). There was no significant difference in the incidence of side effects between the two groups (P>0.05). Conclusion: Combined treatment with cyclophosphamide and glucocorticoid can improve the clinical efficacy of patients with nephrotic syndrome, improve renal function and lipid indexes, and do not increase the incidence of side effects.
  • Clinical practice
    WU Wenbin, YOU Yuting, HUANG Xiaoqiang, HONG Wanqian, ZHENG Jingyang
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    Objective: To analyze the application value of neutrophil to lymphocyte ratio (NLR), lactate dehydrogenase (LDH) and D-dimer (DDR) in evaluation and diagnosis of mycoplasma pneumoniae necrotizing pneumonia (MPNP) in children. Method: A total of 82mycoplasma pneumoniae pneumonia (MPP) children admitted to Quanzhou Maternal and Child Health Hospital and Children's Hospital from June 2022 to June 2024 were selected as the study objects. According to whether they developed necrotic pneumonia (NP), they were divided into MPNP group (39 cases) and non-MPNP group (43 cases). Baseline data and laboratory test results were compared between the two groups, and the influencing factors of MPNP in children with MPP were analyzed by logistic stepstep regression. The working characteristic curve of subjects was drawn, and the area under the curve (AUC) was used to evaluate the predictive efficacy of each influencing factor in MPNP in children with MPP. Result: There were significant differences in NLR, LDH and DDR levels between the two groups (P<0.05). logistic regression analysis showed that NLR, LDH and DDR levels were the influencing factors for MPNP in MPP children (P<0.05). The AUC predicted by NLR, LDH and DDR levels for MPNP in MPP children was 0.759, 0.691 and 0.732, respectively. The AUC predicted by NLR, LDH and DDR levels was 0.858, which was higher than that by single detection, and the difference was statistically significant (P<0.001). The sensitivity and specificity of combined detection were 69.23% and 95.35%. Conclusion: NLR, LDH and DDR levels were significantly correlated with MPNP in children with MPP, and could be used as predictors of MPNP in children with MPP. Combined detection could improve the diagnostic accuracy.
  • Clinical practice
    ZHANG Yi
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    Objective: The combined treatment of butylphthalein and Donepezil hydrochloride was perrformed in elderly patients with vascular dementia after cerebral infarction, and the effects of cerebral blood flow and serum related factor were discussed. Method: A total of 80 elderly patients with vascular dementia after cerebral infarction who received treatment in the People's Hospital of Guangxi Zhuang Autonomous Region from April 2021 to March 2024 were selected as the study objects. They were divided into control group and observation group, with 40 cases in each group. The control group was treated with Donepezil hydrochloride alone, while the observation group was treated with butylphthalein combined with Donepezil hydrochloride. The clinical efficacy, cognitive function, cerebral blood flow status, serum related factors and the occurrence of adverse reactions were compared between the two groups. Result: The total effective rate, Mini-Mental State Examination (MMSE) score, Clinical Dementia Rating (CDR) score, Cerebral Blood Volume (CBV), Cerebral Blood Flow (CBF), Brain-Derived Neurotrophic Factor (BDNF), Angiotensin 1-7 (Ang1-7) and Activities of Daily Living (ADL) score of the observation group were significantly increased compared with the control group, while the other indexes were significantly decreased, with statistical significance (P<0.05). There was no significant difference in the incidence of adverse reactions (P>0.05). Conclusion: In elderly patients with vascular dementia after cerebral infarction, the combination of butylphthalide and Donepezil hydrochloride can achieve satisfactory results, which can improve the blood flow state of the brain, regulate the level of serum related factors, and promote the recovery of cognitive function and improve the ability of daily life.
  • Medical technology and clinical
  • Medical technology and clinical
    CHEN Chao, WANG Xin, DU Huaqing
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    Objective: To investigate the effect of double-pulley knotless suture bridge technique under shoulder arthroscopy on shoulder joint motion and functional repair in patients with rotator cuff tear complicated with osteoporosis. Method: 54 patients with rotator cuff tear complicated with osteoporosis admitted to the People's Hospital of Jiawang District of Xuzhou City from July 2021 to January 2024 were selected as the study objects and randomly divided into two groups, with 27cases in each group. The traditional group was treated with traditional arthroscopic suture bridge fixation, while the observation group was treated with arthroscopic double-pulley suture bridge technique. The pain, shoulder motion and shoulder function of the two groups were compared before and after 3 months of treatment. The mean recovery time, bearing time of affected side and the incidence of joint stiffness and rotator cuff retear were compared between the two groups. Result: After 3 months of treatment, the Numeric Rating Scale (NRS) scores of the two groups were significantly decreased, but the forward flexion, external rotation and abduction were significantly increased, the difference was statistically significant (P<0.05). And compared with the traditional group, the NRS score of the observation group after 3 months of treatment was significantly decreased, and the forward flexion, external rotation and abduction were significantly increased, with statistical significance (P<0.05). Compared with the same group before treatment, the Constant score and the American Society for Shoulder and Elbow Surgery Scoring system (ASES) of both groups were significantly increased, and compared with the traditional group, the Constant score and ASES of the observation group were significantly increased, with statistical significance (P<0.05). Compared with the traditional group, the mean recovery time, bearing time on the affected side and the incidence of joint stiffness and rotator cuff retear in the observation group were significantly reduced, with statistical significance (P<0.05). Conclusion: The double-pulley knotless suture bridge technique under shoulder arthroscopy can significantly promote shoulder joint mobility and functional recovery in patients with rotator cuff tear complicated with osteoporosis, reduce the risk of postoperative complications, and have certain reference value in the formulation of clinical treatment strategies for rotator cuff tear.
  • Medical technology and clinical
    LI Xin, YIN Yanhai, MA Fengli, WANG Meng, MA Zhiying
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    Objective: To explore the influencing factors of bleeding after CT-guided coaxial puncture biopsy of small pulmonary nodules, and to propose corresponding intervention strategies. Method: 168 patients who received CT-guided coaxial puncture biopsy of small pulmonary nodules in Binzhou Central Hospital from January 2019 to December 2023 were selected as the study objects, and their basic information, clinical manifestations, imaging features and postoperative bleeding were collected. Patients with postoperative bleeding were selected as the bleeding group (n=14), and those without postoperative bleeding were selected as the no bleeding group (n=154). Univariate and multivariate logistic regression analysis was applied to explore the influencing factors of postoperative bleeding, and corresponding intervention countermeasures were proposed according to the main risk factors. Result: Compared with the non-bleeding group, the lower lobe accounted for a higher proportion of lesions, the lesion size was smaller, the puncture depth was deeper, the number of samples>2 accounted for a higher proportion of patients, and the pathological results showed a higher proportion of tumor patients, with statistical significance (P<0.05). Multivariate logistic regression analysis showed that the lesion location was lower lobe, lesion size, puncture depth and number of samples were>2, and pathological results showed that tumors could be used as high risk factors for postoperative bleeding after CT-guided coaxial puncture biopsy, with statistical significance (P<0.05). Conclusion: The occurrence of postoperative bleeding after CT-guided coaxial puncture biopsy of small pulmonary nodules is related to many factors. Targeted intervention can effectively reduce the occurrence of postoperative bleeding and improve surgical safety.
  • Medical technology and clinical
    JIANG Defeng, CHEN Yan, WANG Shihui
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    Objective: This study aims to evaluate the effects of the Penumbra system combined with Reco stent interventional thrombectomy on the recanalization rate and hemodynamics in patients with acute ischemic stroke (AIS). Method: Ninety-six patients with acute cerebral infarction admitted to Siyang Hospital of Traditional Chinese Medicine, Affiliated to Yangzhou University Medical College from February 2022 to February 2024 were selected as the study objects, and were divided into study group (n=48) and control group (n=48) according to random number table method. The study group received thrombolysis plus Penumbra system combined with Reco stent, and the control group received thrombolysis. Vascular revascularization rate, hemodynamic parameters [Hematocrit high shear viscosity (HSV), low shear viscosity (LSV), and plasma viscosity (PV)], neurological function [using the National Institutes of Health Stroke Scale (NIHSS)], vascular endothelial function [serum nitric oxide (NO), endothelin (ET)] as assessed by statistical methods, Complications were recorded. Result: After treatment, HSV, LSV and PV in the study group were lower than those in the control group, and the difference was statistically significant (P<0.05). NIHSS score and ET level were lower than control group, the difference was statistically significant (P<0.05). The level of NO was higher than that of control group, and the difference was statistically significant (P<0.05). After treatment, there was no significant difference in the incidence of complications between the two groups (P>0.05). Conclusion: Penumbra system combined with Reco stent can significantly improve the vascular revascularization rate and hemodynamic parameters in patients with acute cerebral infarction.
  • Medical technology and clinical
    SUN Zhiqiang, LU Chenguang, WANG Deyan
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    Objective: To analyze electromyography (EMG) and CT imaging features of patients with lumbar disc herniation (LDH). Method: 90 LDH patients admitted to the Third people's Hospital of Jingzhou from June 2020 to May 2024 were selected as the study objects, and all of them underwent EMG and CT examination. The imaging features were analyzed and compared with the surgical results to analyze the diagnostic coincidence rate. Result: EMG showed that the terminal latency of tibial nerve and common peroneal nerve on the affected side of LDH patients was longer than that on the healthy side, and the amplitude of tibial nerve and common peroneal nerve on the affected side was smaller than that on the healthy side, and the difference was statistically significant (P<0.05). CT showed that the nucleus pulposus was free in the spinal canal of LDH patients and was atrophied/scarring, with protrusion such as adhesion and hill, etc. The coincidence rate between the surgical site and the results of EMG and CT were higher. The terminal latency of tibial nerve and common peroneal nerve on the affected side of LDH patients was shortened and the amplitude was increased, and the difference was statistically significant (P<0.05). The terminal latency of tibial nerve and peroneal nerve on the affected side was shorter in patients with excellent and good curative effect than in patients with fair or poor curative effect, and the difference was statistically significant (P<0.05). The amplitude of tibial nerve and peroneal nerve on the affected side was greater in patients with excellent and good curative effect, and the difference was statistically significant (P<0.05). The proportion of free nucleus pulposus in vertebral canal, frontal protrusion in c~d region, dural sac compression and displacement were higher in patients with good or fair curative effect, and the difference was statistically significant (P<0.05). Conclusion: Patients with LDH have certain EMG and CT features which are coincident with surgical results. The two can also be used to evaluate therapeutic effects.
  • Medical technology and clinical
    YANG Wuliu
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    Objective: To compare the efficacy of total hip arthroplasty and hemiarthroplasty in the treatment of elderly patients with femoral neck fractures. Method: Sixty elderly patients with femoral neck fracture admitted to Qianxi People's Hospital from March 2023 to March 2024 were selected as the study objects, and were divided into control group and observation group by random number table method, with 30 cases in each group. The control group was treated with semi-hip replacement, the observation group was treated with total hip replacement, and the therapeutic effect of the two groups was compared. Result: The intraoperative blood loss, postoperative pain score and incidence of postoperative complications in observation group were higher than those in control group, with statistical significance (P<0.05). Hip function score and total effective rate of treatment in observation group were higher than those in control group, and the difference was statistically significant (P<0.05). Conclusion: Total hip replacement and semi-hip replacement have their respective advantages and disadvantages in the treatment of elderly femoral neck fractures. Among them, total hip replacement can better improve the hip function of patients, but the trauma is greater, while semi-hip replacement has less trauma, but the efficacy is relatively insufficient. It is recommended to choose a reasonable operation according to the actual situation and needs of patients.
  • Modern nursing
  • Modern nursing
    WANG Meilan, ZHANG Liping, WEI Meilan
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    Objective: To explore the application effect of ear acupoint pressing bean method in postoperative rehabilitation after cesarean section. Method: A total of 120 women who underwent cesarean section in the Sixth People's Hospital of Huizhou City from July 2023 to May 2024 were selected as the study objects and randomly divided into observation group and control group, with 60 cases in each group. The control group was given routine postoperative treatment and nursing, and the observation group was given auricular point compression bean method. Postoperative pain score, gastrointestinal exhaust recovery time, uterine rejuvenation time, postpartum blood loss 24 h, milk secretion and incidence of urinary retention were observed and compared between the two groups. Result: The degree of postoperative pain in the observation group was lower than that in the control group, and the difference was statistically significant (P<0.05). The postoperative pain score of the observation group was lower than that of the control group, and the difference was statistically significant (P<0.05). Compared with the control group, the postoperative recovery time of gastrointestinal exhaust and uterine rehabilitation time in the observation group were shorter, and the postpartum blood loss at 24 h was less, with statistical significance (P<0.05). The rate of adequate breastfeeding in the observation group was higher than that in the control group, and the difference was statistically significant (P<0.05). The frequency of milk powder feeding in the observation group was less than that in the control group, and the difference was statistically significant (P<0.05). The incidence of urinary retention in the observation group was lower than that in the control group, and the difference was statistically significant (P<0.05). Conclusion: Auricular point compression method can effectively promote the recovery of the parturient after cesarean section, reduce the postoperative pain, shorten the recovery time and reduce the incidence of complications.
  • Modern nursing
    FU Ting, WEI Xiufang
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    Objective: To explore the effects of humanistic care combined with situational cognitive training on cognitive function, psychological status and quality of life in patients with post-stroke cognitive impairment (PSCI) . Method: A total of 82 patients with PSCI treated in Nanjing Gaochun People's Hospital from January 2022 to May 2024 were selected as the study objects, and were divided into control group and observation group according to envelope randomization method, including control group (n=41, with routine nursing intervention) and observation group (n=41, with humanistic care combined with situational cognitive training mode intervention). The cognitive function, mental state and quality of life of the two groups were assessed by the Montreal Cognitive Assessment Scale (MoCA), the Mini-Mental State Examination (MMSE), the Hospital Anxiety and Depression Scale (HADS), and the Stroke Quality of Life Scale (SS-QOL) before and after the intervention. Result: After intervention, MoCA score, MMSE score, HDS-A score and HDS-D score were decreased in both groups. SS-QOL scale of energy, activity, self-care ability, social role scores increased. After intervention, MoCA score, MMSE score, HDS-A score and HDS-D score in observation group were lower than those in control group, and the differences were statistically significant (P<0.05). The score of SS-QOL was higher than that of control group, and the difference was statistically significant (P<0.05). Conclusion: Humanistic care combined with scene cognitive training mode can improve the cognitive function of PSCI patients, improve the poor mental state and quality of life.
  • Modern nursing
    WU Linxian, SU Zhaoyuan, XU Zhibin
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: To investigate the effect of combined bone-setting manipulation and functional exercise on postoperative rehabilitation in elderly patients with intertrochanteric fracture of femur. Method: Sixty-four elderly patients with intertrochanteric fracture of femur treated in Quanzhou Hospital of Traditional Chinese Medicine from January 2022 to April 2024 were selected as the study objects, and were divided into control group and observation group according to random number table method, with 32 cases in each group. The control group received intervention with routine nursing and functional exercise, and the observation group received intervention combined with bone setting manipulation on the basis of the control group. The clinical indicators, hipfunction [Harris Hip Score (HHS)] on the day of surgery, 1 week after surgery, and 3 weeks after surgery were compared between the two groups, and the ability of daily living [Activity Daily Living Scale (ADL)] before and after intervention was compared between the two groups. Result: After the intervention, the visual analogue score (VAS) of the observation group was lower than that of the control group, and the weight-bearing time, swelling reduction time, getting out of bed time and hospitalization time of the affected limb were shorter than those of the control group, with statistical significance (P<0.05). The HHS scores of the observation group were higher than those of the control group at 1 and 3 weeks after surgery, and the difference was statistically significant (P<0.05). The ADL score of observation group was higher than that of control group after intervention, and the difference was statistically significant (P<0.05). Conclusion: The combination of bone manipulation and functional exercise in postoperative rehabilitation of elderly patients with intertrochanteric fracture of femur can reduce the VAS score of patients, shorten the postoperative recovery time of patients, improve the hip function of patients, and enhance the daily living ability of patients.
  • Modern nursing
    HAN Fengyun
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: The objective of this study is to investigate the influence of perioperative nursing, grounded in the Neuman Systems Model, on the emotional well-being and postoperative recovery of patients undergoing laparoscopic radical gastrectomy for the treatment of gastric cancer, with the goal of providing new ideas and methods for perioperative nursing of gastric cancer patients and promoting the improvement of their overall recovery. Method: A total of 120 patients with laparoscopic radical gastrectomy treated in Jinan Integrated Traditional Chinese and Western Medicine Hospital from January to December 2023 were selected as the study objects and were divided into control group and an observation group by random number table method, with 60 cases in each group. The control group received standard nursing methods, while the observation group received nursing based on the Neuman Systems Model. The nursing effects of the two groups were evaluated and compared using indicators such as the Self-Rating Anxiety Scale (SAS), gastrointestinal function recovery, Health-Related Quality of Life Scale (HRQOL), Self-Rating Depression Scale (SDS), immune function indicators (CD4+T and CD8+T lymphocytes), perioperative indicators, nursing compliance, and nursing satisfaction. Result: After treatment, the scores of SAS, SDS and HRQOL in the observation group were lower than those in the control group, and the difference was statistically significant (P<0.05). Operation time, first time to get out of bed, ventilation time, defecation time and intraoperative fluid volume in the observation group were significantly lower than those in the control group, with statistical significance (P<0.05). And bowel sound recovery time, first feeding time, first exhaust time and hospital stay were also lower than those in the control group, with statistical significance (P<0.05). The proportion of CD4+ T lymphocytes in the observation group was higher than that in the control group at 3 days after surgery and at discharge, with statistical significance (P<0.05). The proportion of CD8+ T lymphocytes was lower than that of control group, and the difference was statistically significant (P<0.05). The nursing compliance and satisfaction of the observation group were also higher than that of the control group, with statistical significance (P<0.05). Conclusion: Perioperative care based on the Neumann system model has shown significant advantages in patients undergoing laparoscopic radical gastrectomy, which can effectively relieve patients' negative emotions and significantly improve their living standards. Promote postoperative recovery and immune function improvement, while enhancing patients' nursing compliance and satisfaction.
  • Modern nursing
    CAO Hua
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: To study the effect of biofeedback therapy combined with hemiplegic limb comprehensive training in stroke patients, and further analyze the impact on limb function and life ability recovery. Method: 120 stroke patients admitted to Xianning Central Hospital from June 2021 to June 2023 were selected as the study objects. According to the random number table, the patients were divided into two groups. 60 patients in the control group received routine intervention. 60 patients in the observation group were treated with biofeedback therapy and comprehensive training of hemiplegic limbs. The therapeutic effect was compared between the two groups. Result: After intervention, the test results showed that the upper limb function score, lower limb function score and total Fugl-Meyer Assessment (FMA) score of the observation group were higher than those of the control group. Barthel index (BI) score, Stroke-Specific Quality of Life Scale (SS-QOL) score and good recovery rate were also higher than those in the control group, and the difference was statistically significant (P<0.05). Conclusion: In the intervention of patients recovering from stroke, stimulation through biofeedback therapy combined with comprehensive training of hemiplegic limbs can help improve their limb function, self-care ability of daily life and quality of life, and can promote the improvement of patient prognosis.
  • Modern nursing
    YE Liyun
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: To explore the effects of positional intervention combined with nasal high-flow humidified oxygen therapy (HFNC) on serum Interleukin IL-6 (IL-6), C-Reactive Protein (CRP), and blood oxygen levels in newborns with pneumonia. Method: 210 newborns with pneumonia treated in our hospital from January 2021 to December 2022 were selected as the subjects of this study and randomly divided into control group and observation group, with 105 cases in each group. The control group was treated with HFNC, and the observation group added positional intervention measures on the basis of the treatment in the control group. The IL-6, C-reactive protein, and blood oxygen indexes before and after treatment in the two groups were compared, and the clinical symptoms and efficacy of the two groups of patients were compared. Result: After treatment, the levels of IL-6, CRP, carbon dioxide partial pressure (PaCO2) and oxygen partial pressure (PaO2) in observation group were significantly lower than those in control group, with statistical significance (P<0.05). The level of arterial oxygen saturation (SpO2) in the observation group was significantly higher than that in the control group, with statistical significance (P<0.05). After treatment, the duration of non-invasive ventilation, heart rate recovery, respiratory improvement and hospitalization in the observation group was significantly lower than that in the control group, with statistical significance (P<0.05). The total effective rate of the observation group was significantly higher than that of the control group, and the difference was statistically significant (P<0.05). Conclusion: Positional intervention combined with HFNC can effectively reduce the inflammation level of newborns with pneumonia, improve their blood oxygen indicators and clinical symptoms, and improve their clinical efficacy.
  • Experience
  • Experience
    FENG Zihao, XU Wen, CUI Wenying
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    Objective: To explore the clinical effect of Xiaojin Tang combined with navel stickers and spinal compression in the treatment of pediatric sweating syndrome. Method: A total of 86 children with sweating syndrome (lung wei deficiency syndrome) treated in Zhaotong Hospital of Traditional Chinese Medicine from October 2022 to July 2023 were selected as the research objects, and were divided into control group and research group according to random number table method, with 43 cases in each group. The control group was given Yupingfeng oral liquid, while the study group was given Xiaojin Decoction combined with nawel stickers and chiropractic treatment on the basis of the control group. TCM syndrome score, therapeutic effect and occurrence of adverse reactions were compared between the two groups. After 6 months of follow-up, the recurrence rate of the two groups was analyzed. Result: Before treatment, there was no significant difference in the scores of main syndrome sweating and secondary syndrome fatigue, thirst and bad wind between the two groups (P>0.05). After treatment, the scores of the 4 indicators of sweating, fatigue, thirst and bad wind in the two groups were decreased, and the study group was lower than the control group, and the difference was statistically significant (P<0.05). After treatment, the total clinical effective rate of the study group was higher than that of the control group, and the difference was statistically significant (P<0.05). After treatment, there was no significant difference in the total adverse reaction rate between the two groups (P>0.05). After 6 months of treatment, the recurrence rate of control group was higher than that of study group, and the difference was statistically significant (P<0.05). Conclusion: Xiaojin Decoction combined with navel patch and chiropractic treatment can effectively improve the TCM syndromes of children with good clinical efficacy, low adverse reaction rate, high safety and low recurrence rate.
  • Experience
    WU Yangyang
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    Objective: To explore the clinical effect of Yangxin Jianpi Tang combined with acupuncture in the treatment of pediatric anorexia with heart spleen imbalance. Method: A total of 102 children with anorexia with heart spleen imbalance treated in Liyang Hospital of Chinese Medicine from February 2022 to February 2023 were selected as the study objects and divided into control group and study group according to random number table method, with 51 cases in each group. The control group was treated with conventional western medicine, and the study group was treated with Yangxin Jianpi Decoction combined with acupuncture. TCM syndrome score, blood trace element level (zinc, calcium and iron), gastrointestinal hormone (motilin, gastrin, neuropeptide Y), occurrence of adverse reactions (vomiting, diarrhea, fatigue) and efficacy were compared between the two groups after intervention. Result: After intervention, the scores of appetite loss, abdominal distension and fatigue syndrome in the study group were lower than those in the control group, and the differences were statistically significant (P<0.05). After intervention, serum zinc, calcium and hot metal in the study group were higher than those in the control group, and the difference was statistically significant (P<0.05). The levels of motilin, gastrin and neuropeptide Y in the study group were higher than those in the control group, and the difference was statistically significant (P<0.05). After intervention, the incidence of adverse reactions in study group was lower than that in control group, and the difference was statistically significant (P<0.05). After intervention, the total effective rate of the study group was higher than that of the control group, and the difference was statistically significant (P<0.05). Conclusion: Yangxin Jianpi Decoction combined with acupuncture in the treatment of children with heart-spleen disorder anorexia can improve the symptoms of children, increase the level of blood trace elements and gastrointestinal hormones, and reduce the incidence of adverse reactions.
  • Experience
    HU Zhaohui
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    Objective: To explore the clinical effect of different doses of Pulmonary surfactant (PS) combined with non-invasive high frequency oscillatory ventilation (NHFOV) on respiratory distress syndrome (RDS) of premature infants. Method: A total of 60 children with RDS treated in Daye People's Hospital from January 2020 to June 2023 were selected as the study objects and divided into control group and observation group according to random number table, with 30 cases in each group. The two groups were treated with PS combined with NHFOV on the basis of conventional treatment, in which the control group was given a low dose of PS (100 mg/kg) and the observation group was given a high dose of PS (150 mg/kg). The clinical efficacy, mechanical ventilation parameters [respiratory rate (RR), inhaled oxygen concentration (FiO2), positive end-expiratory pressure (PEEP), peak inspiratory pressure (PIP)], blood gas indexes [pH value, arterial partial pressure of oxygen (PaO2), arterial partial pressure of carbon dioxide (PaCO2)] and the incidence of complications were compared between the two groups before treatment and 3 days after treatment. Result: After treatment, the clinical efficacy of the observation group was higher than that of the control group, and the difference was statistically significant (P<0.05). After treatment, the levels of RR, FiO2, PEEP and PIP in observation group were lower than those in control group, and the differences were statistically significant (P<0.05). After treatment, pH and PaO2 in observation group were higher than those in control group, and PaCO2 was lower than those in control group, and the difference was statistically significant (P<0.05). After treatment, the incidence of complications in the observation group was lower than that in the control group, and the difference was statistically significant (P<0.05). Conclusion: High-dose PS combined with NHFOV is effective in the treatment of RDS children, which can effectively improve the mechanical ventilation parameters and blood gas indexes of children, reduce the incidence of complications, and facilitate rehabilitation.
  • Experience
    WU Shuangmei, WU Wenzong, LIAO Xingming
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    Objective: To investigate the effect of Guishao Lizhong Decoction combined with acupuncture therapy on functional constipation (Qi deficiency and Yang deficiency type) and the effects of intestinal flora homeostasis. Method: A total of 100 patients with functional constipation (Qi deficiency and Yang deficiency type) admitted to the Second Hospital of Sanming City from January 2020 to December 2023 were selected as research objects and divided into control group and experimental group according to random number table method, with 50 cases in each group. The control group was treated with Guishao Lizhong Decoction, and the experimental group was treated with Guishao Lizhong Decoction combined with acupuncture therapy. After 4 weeks of treatment, the clinical efficacy, intestinal flora homeostasis, TCM symptom score and constipation symptom score of the two groups were compared. Result: The total effective rate of the experimental group was higher than that of the control group, and the difference was statistically significant (P<0.05). After treatment, the level of enterobacter in the experimental group was lower than that in the control group, and the level of bifidobacterium and lactobacillus was higher than that in the control group, with statistical significance (P<0.05). After treatment, the scores of difficult defecation, dry stool, prolonged defecation time and cold fatigue in the experimental group were lower than those in the control group, and the difference was statistically significant (P<0.05). After treatment, the defecation effort, defecation frequency and defecation trait score of the experimental group were lower than those of the control group, and the differences were statistically significant (P<0.05). Conclusion: In the treatment of patients with functional constipation (Qi deficiency and Yang deficiency type), the application of Guishao Lizhong Decoction combined with acupuncture therapy can further improve the curative effect, improve the homeostasis of intestinal flora, and promote the effective relief of patients' symptoms.
  • Experience
    YANG Zhenyu, FANG Neng
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    Objective: To analyze the effect of budesonide inhalation, azithromycin sequential therapy combined with Chinese medicine acupoint application in children with mycoplasma pneumonia (MPP). Method: A total of 116 children with MPP treated in Putian Hanjiang Hospital from January 2020 to October 2023 were selected as the study objects, and were divided into control group and observation group according to random number table method, with 58 cases in each group. The control group was given budesonide suspension aerosol inhalation plus azithromycin sequential therapy. On the basis of control group, the observation group was given Chinese medicine acupoint application. The clinical efficacy, symptom disappearance time, inflammatory index, pulmonary function index and adverse reaction were compared between the two groups. Result: The total effective rate of the observation group after treatment was significantly higher than that of the control group, and the difference was statistically significant (P<0.05). The disappearance time of all symptoms was shorter than that of control group, and the difference was statistically significant (P<0.05). The levels of C-reactive protein (CRP), serum soluble interleukin -2 receptor (sIL-2R), Granulocyte Stimulating Factor (G-CSF) and forced vital capacity (FVC) were lower than those of control group, Forced Respiratory Volume in One Second (FEV1) and Peak Expiratory Flow (PEF) were higher than those of control group, and the difference was statistically significant (P<0.05). There was no significant difference in adverse reactions between the two groups (P>0.05). Conclusion: Chinese medicine acupoint application combined with budesonide atomization inhalation and azithromycin sequential therapy in the treatment of MPP children can enhance the curative effect, accelerate the time of symptom disappearance, reduce the inflammatory response of the body, improve the level of lung function, and have high drug safety.
  • Experience
    ZHAO Wei, XU Jie, XIONG Shijun
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    Objective: To analyze the effects of free position delivery combined with pelvic compression based on guided multi position changes on the outcomes ofOccipitoposterior Position And Occipitotransverse Postion. Method: 100 parturients of postoccipital and transverse parturients who received treatment in Linyi Centeal Hospital from April 2023 to July 2024 were selected as research objects. And they were randomly divided into observation group and control group, with 50 cases in each group. During delivery, the observation group adopted free position delivery based on guided multiple position changes combined with pelvic compression intervention to change the delivery mode, while the control group continued to follow the traditional lithotomy position delivery mode. The outcomes of delivery and related indicators (labor time, fetal and newborn conditions, maternal satisfaction rate, postpartum quality of life) of the two groups were compared. Result: The results of delivery outcomes and related indicators (labor time, fetal and newborn conditions, maternal satisfaction rate, postpartum quality of life) in the observation group were better than those in the control group, with statistical significance (P<0.05). Conclusion: The free position delivery combined with pelvic compression intervention with guided multiple position changes can significantly optimize the delivery process and achieve better maternal and infant health outcomes for women in occipito-posterior and occipito-transverse positions. This intervention not only helps to shorten labor time, but also improves postpartum quality of life, thereby enhancing maternal satisfaction and experience.
  • Experience
    HUANG Li, GUO Xiaowei, FENG Yumei, YANG Junyi
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    Objective: To investigate the effect of acupuncture combined with low-frequency repetitive transcranial magnetic stimulation (rTMS) on improving the walking function of children with spastic cerebral palsy. Method: A total of 62 children with spastic cerebral palsy admitted to the Children's College, Fuzhou First General Hospital (Fuzhou Children's Hospital of Fujian Province) from January 2022 to January 2024 were selected as the study objects, and were randomly divided into control group (low-frequency repetitive transcranial magnetic stimulation) and observation group (acupuncture combined with low-frequency repetitive transcranial magnetic stimulation), with 31 cases in each group. The therapeutic effect of the two groups was compared. Result: After treatment, the walking function index, Gross Motor Function Scale (GMFM) score, 10 m walking time (10MWT) and Fugel-Meyer Assessment Scale (FMA) score in observation group were better than those in control group, and the differences were statistically significant (P<0.05). Conclusion: Acupuncture combined with low frequency rTMS can significantly improve walking function in children with spastic cerebral palsy.
  • Experience
    ZHAO Aibing, ZHAO Yuming, FENG Guiyou
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    Objective: To investigate the clinical efficacy of the supine direct anterior approach (DAA) and the posterolateral approach (PLA) of the hip joint in total hip arthroplasty in femoral neck fracture and femoral head necrosis. Method: A total of 64 patients with total hip arthroplasty admitted to Taixing Third People's Hospital of Jiangsu Province from January 2020 to December 2023 were selected as the study objects, and were divided into DAA group (32 cases, DAA treatment) and PLA group (32 cases, PLA treatment) according to different surgical protocols. Both groups were followed up until 12 months after surgery. Perioperative indexes, pain degree, hip function, walking function and complications were compared between the two groups at different times (preoperative, 1 month, 3 months, 6 months, 12 months). Result: The operation time of PLA group was shorter than DAA group, and the intraoperative blood loss and postoperative drainage volume were higher than DAA group (P<0.05). Visual analogue scale (VAS), hip Harris score and 10 m walking time of DAA group were similar to those of PLA before surgery, 1 month and 12 months after surgery (P>0.05). 3 months and 6 months after operation, VAS score and 10 m walking time in DAA group were lower than those in PLA group, and hip joint Harris score was higher than those in PLA group (P<0.05). The complication rate of DAA group was lower than that of PLA group (P<0.05). Conclusion: In total hip replacement, PLA can shorten the operation time, but DAA can reduce the surgical trauma of patients, and 3 months and 6 months after surgery, DAA can reduce the pain degree of patients, improve their hip function and walking ability, and reduce the incidence of complications.
  • Synthetic medicine
  • Synthetic medicine
    CUI Xingfang, ZHAI Hong
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    Objective: To explore the clinical effect of superpulse CO2 lattice laser combined with compound glycyrrhizin on patients with vitiligo. Method: A total of 84 patients with vitiligo who were treated in Liupanshui People's Hospital from January 2022 to October 2023 were selected as the study objects and divided into study group and control group by random number table method, with 42 cases in each group. The control group was treated with superpulse CO2 lattice laser, and the study group was treated with superpulse CO2 lattice laser combined with compound glycyrrhizin. After 6 months of intervention, the clinical efficacy of the two groups was observed, and the white spot area, skin recolor rate, immune indexes, inflammatory indexes and the occurrence of adverse reactions were compared between the two groups. Result: The total effective rate of the study group was higher than that of the control group, and the difference was statistically significant (P<0.05). After treatment, the white plaque area of the study group was smaller than that of the control group, the recolor rate of skin lesions was higher than that of the control group, the levels of serum interleukin-17 (IL-17), interleukin-23 (IL-23) and CD8+ were lower than those of the control group, and the levels of CD3+ and CD4+ were higher than those of the control group, with statistical significance (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion: Superpulse CO2 lattice laser combined with compound glycyrrhizin tablets can effectively reduce the patient's white spot area, improve the patient's immune and inflammatory indexes, with high safety and good clinical efficacy.
  • Synthetic medicine
    CAI Huangjie, LIN Chengzu, CAI Bing
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    Objective: To analyze the effects of combination therapy with linezolid and cycloserine capsules on X-pert MTB/RIF test results and lung function levels in patients with multidrug-resistant pulmonary tuberculosis. Method: 79 patients with multidrug-resistant tuberculosis admitted to Jinjiang Hospital from July 2021 to June 2023 were selected as the study objects for retrospective treatment study. All patients received investigatory drug treatment during this period. The patients treated with Elinezolid were the reference group (39 cases), and the patients treated with Elinezolid combined with cycloserine capsule were the study group (40 cases). The levels of lung ventilation function and cellular immune function before and after treatment were compared between the two groups. After treatment, the results of X-pert MTB/RIF detection, the improvement time of clinical symptoms, the negative conversion rate of tuberculosis in sputum, the effective rate of treatment and the incidence of adverse drug reactions. Result: Compared with the control group, the levels of ventilatory function, CD4+, CD8+ and CD4+/CD8+ in the study group after cycloserine combined treatment were increased, and the differences were statistically significant (P<0.05). The positive detection rate of X-pert MTB/RIF was decreased (15.00%), the negative conversion rate of sputum tuberculosis bacillus was increased (85.00%), and the effective rate of treatment was increased (92.50%), with statistical significance (P<0.05). The time of focal area reduction, sputum culture to negative time, acid-fast staining smear to negative time and pulmonary cavity closure time were shortened, and the differences were statistically significant (P<0.05). There was no significant difference in the incidence of adverse drug reactions between the two groups (P>0.05). Conclusion: The combined treatment of linezolid and cycloserine capsule in patients with MDR-TB has a definite effect, which can reduce the positive detection rate of X-pert MTB/RIF, promote the negative transformation of sputum tuberculosis, and regulate the lung function and cellular immune function of patients, without obvious risk of toxic and side effects, and has clinical safety.
  • Synthetic medicine
    YU Jiawei, LI Beibei, MA Li, TU Mingfeng
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    Objective: To explore the effect of modified Tongqiao Huoxue decoction in the treatment of acute cerebral infarction and its influence on inflammation and lipoprotein-associated phospholipase A2 (Lp-PLA2). Method: A total of 120 patients diagnosed with ACI admitted to the Department of Neurology, Liyang Hospital of Chinese Medicine from February 2022 to January 2024 were included in the study, and were divided into control group and observation group according to computer random number table method, with 60 cases in each group. The control group was treated with conventional western medicine, while the observation group was treated with Tongqi Huoxue decoction on the basis of the control group. Laboratory indicators (serum and inflammatory factor levels), clinical efficacy, and adverse reactions were compared between the two groups. Result: There was no difference in serum, inflammatory factors, and TCM symptom scores before treatment between the two groups (P>0.05). After treatment, all indicators in the two groups were lower than those before treatment, and the indicators in the observation group were lower than those in the control group (P<0.05). The curative effect of the traditional Chinese medicine group was higher than that of the western medicine group (P<0.05). There was no difference in adverse reactions between the two groups (P>0.05). Conclusion: The application of Tongqi Huoxue decoction combined with Western medicine in the treatment of acute cerebral infarction has a remarkable effect, which can alleviate clinical symptoms, promote blood circulation, reduce inflammation, and have a remarkable therapeutic effect.
  • Synthetic medicine
    WU Dan, WANG Le, MA Baoman, LIN Chujuan, GONG Ying
    Abstract ( ) PDF ( ) Knowledge map Save
    Objective: To observe the clinical effect of acupuncture acupuncture by Zhuang medicine combined with medicine ironing on primary dysmenorrhea of qi stagnation and blood stasis type. Method: 60 patients with primary dysmenorrhea admitted to International Zhuang Medicine Hospital Affiliated to Guangxi University of Traditional Chinese Medicine from January 2020 to June 2024 were selected as the subjects of this study, and were divided into two groups according to 1:1 ratio by random mode. The control group was treated with oral ibuprofen. While the observation group was treated with Zhuang medicine acupuncture combined with medicine ironing. The treatment continued for 3 menstrual cycles. Visual analogue Scales (VAS) scores and TCM syndrome scores were compared between the two groups after treatment, and the clinical efficacy and incidence of adverse reactions were observed after 3 menstrual cycles of treatment. Result: After treatment, dysmenorrhea symptoms were alleviated in both groups, and VAS scores and TCM syndrome scores were significantly improved, with statistical significance (P<0.05). Compared with the specific improvement degree of the two groups, the improvement of TCM syndrome scores in the observation group was more obvious, and the effect was faster and more stable, with statistical significance (P<0.05). The adverse reaction rate of the observation group was lower while the curative effect was better, and the difference was statistically significant (P<0.05). Conclusion: Compared with single painkiller treatment, Zhuang medicine acupuncture combined with medicine ironing has better effect on the treatment of primary dysmenorrhea with qi stagnation and blood stasis. The clinical effect is significant, stable, painless, easy to operate, and less side effects.
  • Synthetic medicine
    XU Rui, LV Shuqin, GUO Yijuan, QIN Hongyu, ZHAO Nengjiang
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    The article explores the pathogenesis of Polycystic Ovary Syndrome (PCOS) based on the imbalance in the relationships among the five elements of the zang-fu organs. The primary pathogenesis includes lung metal generating kidney water, kidney water nourishing liver wood, heart fire insulting kidney water, spleen earth restraining kidney water, and cellular obstruction as well as phlegm stasis blocking collaterals. In the treatment of syndrome differentiation, one should commence with the regulation of the relationships among the zang-fu organs, tonify the lungs and kidneys, nourish the liver and kidneys, communicate the heart and kidneys, tonify the kidneys and relieve the spleen, address the pathological contradictions of "deficiency, phlegm, stasis, and stagnation", and restore the normal ovulation and menstruation functions of women.
  • Review
  • Review
    YANG Meijuan, ZHOU Chunming, LUO Huali
    Abstract ( ) PDF ( ) Knowledge map Save
    The incidence of renal anemia is increasing with the progress of chronic kidney disease (CKD). At present, the awareness rate and treatment rate of renal anemia in China are low, which not only endangers the physical and mental health of patients, but also brings huge economic burden to them. At present, Western medicine mainly treat renal anemia with iron, hypoxy-inducing factor prolyl hydroxylase inhibitor (HIF-PHI), erythropoietic stimulant, blood transfusion and so on. The treatment of renal anemia by traditional Chinese medicine is varied and effective, but there are still some shortcomings, such as unclear mechanism of action and small sample size. The article will discuss the current treatment methods and related research progress of renal anemia from the perspectives of Western medicine and Chinese medicine.
  • Review
    LEI Yumeng, LEI Jing
    Abstract ( ) PDF ( ) Knowledge map Save
    Non-small cell lung cancer (NSCLC) is the main type of lung cancer, and about 30% of NSCLC patients are in the resectable range when diagnosed. However, the long-term prognosis of patients after radical resection is not ideal, and the main reason for the poor long-term prognosis of patients is tumor recurrence and metastasis. In order to improve the long-term prognosis of patients with resectable NSCLC, the comprehensive treatment strategy of radical surgery combined with perioperative radiotherapy and chemotherapy is often used in clinic, but the curative effect is limited. Therefore, the treatment of resectable NSCLC has always been the focus and hotspot of clinical research. In recent years, immune checkpoint inhibitors (ICIs) have been used in the treatment of various advanced malignant tumors and achieved good results. However, the exploration of combined immunotherapy strategies in the context of comprehensive treatment of resectable NSCLC and the toxicity and side effects are still controversial. To this end, this article reviews the studies on perioperative immunotherapy in patients with resectable NSCLC, aiming to provide reference for comprehensive treatment in patients with resectable NSCLC.
  • Review
    YANG Kangshuai, ZHANG Dongyang, LIU Enkun, WANG Yawen, ZHANG Wei
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    Cervical spondylosis is a common and frequently occurring disease in clinic, and cervical spondylotic radiculopathy (CSR) is the highest incidence rate of all types of cervical spondylosis, which is common in middle-aged and elderly people. The rapid development of electronic products has changed the way people work and live, and the incidence of CSR is gradually becoming younger. This disease is not only a physical torment, but also causes huge mental harm in the long run. CSR is often treated conservatively, such as acupuncture and moxibustion, massage, traction, drug oral administration, nerve block and other methods. The above methods have achieved good therapeutic effects in clinical practice, but due to their slow onset of CSR and the pain or other side effects caused by the treatment process, patients are prone to resistance. Mulligan technology has the characteristics of fast efficacy and painlessness, and has gradually been used by many doctors for clinical treatment of CSR. This article summarizes the research progress of Mulligan technology in treating CSR in recent years, in order to provide a basis for future Mulligan technology treatment of CSR.
  • Review
    SHI Yi, QU Yuan
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    Abdominal trauma may lead to abdominal infection, which is a serious complication that requires timely diagnosis and treatment. Abdominal trauma includes injuries caused by various reasons, such as car accidents, knife wounds, gunshot wounds, falls, etc. The severity and risk of abdominal infection depend on the nature of the injury and the organs involved. If timely and effective diagnosis and treatment are not obtained in the event of abdominal infection, it can pose a great threat to patients and even lead to death. Therefore, timely diagnosis and subsequent treatment for patients with abdominal trauma combined with abdominal infection are key measures to improve patient prognosis. Based on this, this article provides a research review on the diagnosis and treatment of patients with abdominal trauma combined with abdominal infection, aiming to provide clinical reference for the diagnosis and treatment of abdominal trauma combined with abdominal infection.
  • Review
    ZHANG Haiyun, ZHAO Wulan
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    Tinnitus has always caused great trouble to patients' lives, and the prevalence of tinnitus is showing a gradual increase, and the reasons for tinnitus are diverse. With the increasing level of industrialization of society, noise exposure has become more common and complex, and has become one of the most common causes of hearing loss. In this context, the phenomenon of tinnitus induced by noise exposure is becoming more and more common. However, the mechanism of noise induced tinnitus has not been clearly explained. Recent studies have hypothesized that the mechanism is "noise exposure-cochlear strap synaptic damage-peripheral afferent signal reduction-auditory center overcompensation-central hyperexcitability-tinnitus occurrence". This article reviews the relationship between noise exposure and tinnitus.
  • Review
    ZHANG Liran, ZHANG Ziya, HAN Xiangyu
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    Since non-ST elevation myocardial infarction (NSTEMI) is associated with multiple chronic diseases and has a high incidence of major adverse cardiac events, MACEs (MACEs), in order to better evaluate the prognosis of NSTEMI patients, this paper summarized traditional predictors such as GRACE (Global Register of Acute Coronary Events) scores and novel biological indicators. In order to provide patients with personalized diagnosis and treatment plan.
  • Review
    ZHANG Wenjing, ZHU Weihong
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    Patients with overactive bladder experience a significant impact on quality of life due to urinary control issues, and may even develop long-term complications. The efficacy of conventional Western medicine treatments is not satisfactory. This article collected, organized, and analyzed literature on the treatment of overactive bladder with traditional Chinese external therapy methods from the China National Knowledge Infrastructure database from 2012 to 2024. It was found that methods such as moxibustion, acupoint application, acupuncture, catgut embedding at acupoints, massage, herbal foot baths, fire dragon therapy, acupoint massage, and auricular therapy all have significant therapeutic effects on overactive bladder. Most of these methods are characterized by relatively stable long-term efficacy and few adverse reactions. The article discusses the current research status of traditional Chinese external therapy methods in treating overactive bladder, guides clinical treatment, and explores future research directions.
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