Medical technology and clinical
ZHANG Dongyu, FANG Jie, REN Fengying, Lü Hongli
Objective: To investigate the effect of keratoplasty on corneal function and visual acuity recovery in adolescent myopic patients. Method: The data of 120 adolescent myopia patients (186 eyes) who underwent visual acuity examination and correction at the First Affiliated Hospital of Xiamen University from July 2021 to January 2024 were retrospectively analyzed, and based on the different correction methods, they were divided into the control group (59 cases and 91 eyes wearing conventional myopia spectacles), and the plasmapheresis group (61 cases and 95 eyes wearing keratoplasty lenses continuously for 6 months). Corneal function and visual acuity were examined before, 1 week, 1 month, 3 months, and 6 months after lens wear and the number of corneal endothelial cells, corneal refractive error, intraocular pressure length, ocular axis, corneal thickness, anterior and posterior surface high-order aberration, and naked-eye visual acuity (UCVA) were compared between the two groups. Result: Corneal refraction, axial length, and corneal thickness were significantly reduced in both groups at 1 week, 1 month, 3 months, and 6 months after wearing the lenses, and the refraction was higher in the plastic lens group than in the control group at all time points, and the axial length and corneal thickness were lower than those in the control group, and the difference was statistically significant (P<0.05). The anterior surface high-order aberration was higher than that before lens wear in both groups at 1 week, 1 month, 3 months, and 6 months after lens wear, and the anterior surface high-order aberration was higher in the plastigraphy group than that in the control group at all time points, and the difference was statistically significant (P<0.05). The UCVA (logMA) of the plastic lens group was better than that of the control group at 1 week, 1 month, 3 months, and 6 months after lens wear, and the difference was statistically significant (P<0.05). Pearson's parametric correlation analysis showed that corneal refraction, corneal thickness, and ocular axis length were positively correlated with naked-eye distance visual acuity (UDVA), and anterior surface higher-order aberrations were negatively correlated with UDVA in myopia patients at 6 months after lens wear (P<0.05). Conclusion: The recovery of corneal function and visual acuity is most obvious 1 week after keratoplasty in adolescent myopic patients, while continuous wearing of keratoplasty lenses for 6 months can effectively improve patients' corneal function and naked-eye visual acuity.
