Most Read
  • Published in last 1 year
  • In last 2 years
  • In last 3 years
  • All

Please wait a minute...
  • Select all
    |
  • Experience
    LI Guiqiong, ZHOU Kunli, ZHU Lanyu, ZHAO Xiaoyan
    Chinese And Foreign Medical Research. 2025, 23(11): 133-136. https://doi.org/10.14033/j.cnki.cfmr.2025.11.035
    Objective: To investigate the clinical value of Compound Glycyrrhizin combined with Isotretinoin in the treatment of papulopustular rosacea. Method: A total of 100 patients with papulopustular rosacea admitted to the Dermatology Department of the First Affiliated Hospital of Xiamen University from January 2022 to July 2024 were selected and randomly divided into two groups using the random number table, with 50 patients in each group. The control group was treated with Isotretinoin Capsules alone, while the observation group was treated with Compound Glycyrrhizin Tablets in addition to Isotretinoin Capsules. The treatment effect and improvement of skin damage in two groups of patients were observed and analyzed through dermatoscopy, and the levels of serum inflammatory factors [interleukin-8 (IL-8) and transforming growth factor-β1 (TGF-β1)] were compared before and after treatment. Adverse events during treatment was also recorded. Result: Compared with the control group, the total effective rate of the observation group was higher, and the difference was statistically significant (P<0.05). After treatment, the skin lesion score of both groups were decreased, and the observation group was lower than the control group, the differences were statistically significant (P<0.05). After treatment, the levels of IL-8 and TGF-β1 in both groups were decreased, and the levels of the observation group were lower than those of the control group, the differences were statistically significant (P<0.05). The incidence of adverse events in the observation group was slightly higher than that in the control group, the difference was not statistically significant (P>0.05). Conclusion: The combination of Compound Glycyrrhizin and Isotretinoin has shown significant therapeutic effects in treating papulopustular rosacea, effectively improving skin damage, reducing inflammatory cytokine levels, and has good safety.
  • Review
    LI Zongxuan
    Chinese And Foreign Medical Research. 2025, 23(19): 180-184. https://doi.org/10.14033/j.cnki.cfmr.2025.19.047
    Gastroesophageal reflux disease (GERD) is a common chronic digestive disorder characterized by symptoms such as reflux, heartburn, bloating, belching, and chest pain, which can lead to severe complications like esophageal adenocarcinoma. With the ongoing social and economic development and lifestyle changes, the prevalence of GERD continues to rise, particularly in Asian countries. Although proton pump inhibitors (PPIs) are considered as the first-line treatment, monotherapy presents limitations, such as incomplete symptom relief and long-term safety concerns. Therefore, recent treatment strategies have gradually shifted towards diversification and personalization. The study summarizes the latest advances in GERD treatment, including the use of acid-suppressing agents, prokinetics, mucosal protectants, reflux inhibitors, and neuromodulators, as well as non-pharmacological interventions such as endoscopic and surgical therapies. Additionally, the treatment characteristics for special populations, including children, the elderly, and pregnant women, are discussed. By optimizing combination therapy and individualized approaches, the clinical outcomes for GERD patients and their quality of life are expected to improve further.
  • Article
    LIAO Jianbin, YAN Yongzhong, FANG Jieming
    Chinese And Foreign Medical Research. 2025, 23(23): 1-4. https://doi.org/10.14033/j.cnki.cfmr.2025.23.001
    Objective: To explore the impact of adenoidectomy on nasal inflammation control and Th1/Th2 cell balance in children with adenoid hypertrophy and allergic rhinitis (AR). Method: 100 children with adenoid hypertrophy combined with allergic rhinitis who were treated at Puning People's Hospital from June 2022 to June 2024 were selected and randomly divided into a control group (treated with drugs, n=50) and an observation group (treated with drugs plus adenoidectomy, n=50) according to the random number table method. The control of rhinitis in the two groups, the levels of inflammatory factors [tumor necrosis factor-α (TNF-α), leukocyte mediators (IL)-4, IL-6, interferon-γ(INF-γ)] before and after treatment, and the occurrence of adverse reactions were compared. Result: The total effective rate of treatment in the observation group was higher than that in the control group, and the difference was statistically significant (P<0.05). After treatment in both groups, the levels of TNF-α, IL-4 and IL-6 decreased, and those in the observation group were lower than those in the control group. The level of INF-γ increased in both groups, and that in the observation group was higher than that in the control group. The differences were statistically significant (P<0.05). The occurrence of adverse reactions in the observation group was higher than that in the control group, but the difference was not statistically significant (P>0.05). Conclusion: Adenoidectomy can effectively increase the total effective rate of treatment for children with adenoid hypertrophy accompanied by AR, reduce the levels of inflammatory factors, and subsequently regulate the Th1/Th2 cell balance, with high safety.
  • Review
    LI Yufeng, XIONG Jiawei
    Chinese And Foreign Medical Research. 2025, 23(13): 181-184. https://doi.org/10.14033/j.cnki.cfmr.2025.13.046
    Nervous tinnitus, as one of the most common clinical tinnitus symptoms, causes serious damage to the patient's physical and mental health and quality of life. At present, there is a lack of effective therapeutic drugs for nervous tinnitus in clinical practice, acupuncture have good effects and safety in the treatment of nervous tinnitus, and the methods of acupuncture in the treatment of nervous tinnitus are becoming more and more abundant, under the guidance of traditional Chinese medicine theory, it can effectively reduce the severity of symptoms, ensure the therapeutic effect, and play a positive role in improving physical and mental health. This article is a brief summary of the etiology and pathogenesis of nervous tinnitus and the methods of acupuncture treatment of nervous tinnitus, hoping to provide an effective reference for the treatment of neural tinnitus.
  • Synthetic medicine
    ZHU Mingyang
    Chinese And Foreign Medical Research. 2025, 23(12): 164-168. https://doi.org/10.14033/j.cnki.cfmr.2025.12.043
    Objective: The purpose of this study is to investigate the clinical effectiveness of Xiangsha Liujunzi Decoction combined with moxibustion in the treatment of chronic atrophic gastritis, providing new insights and reference for the treatment of this disease. Method: 126 patients with chronic atrophic gastritis admitted to Beijing Huairou District Hospital of Traditional Chinese Medicine from September 2022 to September 2023 were randomly divided into control group and observation group, with 63 patients in each group. The control group was treated with conventional western medicine combined with Xiangsha Liujunzi decoction, and the observation group was treated with moxibustion on this basis. Clinical efficacy, levels of inflammatory factors and Gastrin (GAS), gastroscopy and pathological improvement, and Short Form 36-item Health Survey (SF-36 score) were compared between the two groups before and after treatment to evaluate the effects of different treatments. Result: There were no significant differences in age, gender, course of disease and other baseline data between the two groups (P>0.05). The effective and the total effective rate of the observation group, significantly higher than those of the control group (P<0.05). After treatment, compared with the control group, the CRP level and IL-6 level in the observation group were significantly decreased, and the GAS level was significantly increased. The reduction range in the observation group was greater than that in the control group, and the difference was statistically significant (P<0.05). After six months of follow-up, gastroscopy and pathological improvement showed that the observation group was better than the control group in terms of inflammation remission, atrophy improvement and intestinal metaplasia reversal, and the difference was statistically significant (P<0.05). The SF-36 score of quality of life showed that the improvement of physical function, role function, emotional health and vitality in the observation group was better than that in the control group, and the difference was statistically significant (P<0.05). Conclusion: The combination of Xiangsha Liujunzi Decoction and moxibustion in the treatment of chronic atrophic gastritis can significantly improve clinical effectiveness, reduce levels of inflammatory factors, promote the recovery of gastric pathological conditions, and enhance patients' quality of life. This combined therapy is an effective method for treating chronic atrophic gastritis.
  • Clinical practice
    DENG Jumei, LI Meirong, LI Xiaoting
    Chinese And Foreign Medical Research. 2025, 23(12): 29-32. https://doi.org/10.14033/j.cnki.cfmr.2025.12.008
    Objective: To investigate the clinical efficacy of secuchiumab in the treatment of ankylosing spondylitis and its effect on spinal function. Method: 80 patients with ankylosing spondylitis (AS) admitted to Jinjiang City Hospital from January 2022 to January 2024 were selected as the study objects. They were divided into Adamu group and Secuchiu group according to different medication regimens, with 40 cases in each group. Adamu group received adamumab treatment, while the Secuchiumab group received secuchiumab treatment, and all patients continued to receive treatment for 3 months. The treatment effectiveness of the two groups was compared. Spinal function (ankylosing spondylitis Function Index (BASFI), Bath Ankylosing Spondylitis Metrology index (BASMI), morning stiffness duration], laboratory indicators [erythrocyte subsidence rate (ESR), C-reactive protein (CRP)] and drug safety were compared between the two groups before and after treatment. Result: The effective rate of Sikuchiyou group was higher than that of Adamu group, and the difference was statistically significant (P<0.05). After treatment, the BASFI and BASMI of Secuchiyou group were lower than those of Adamu group, the duration of morning stiffness was shorter than that of Adamu group (P<0.05). After treatment, compared with Adamu group, both ESR and CRP in Secuchiu group were lower (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion: The treatment effect of secuchiumab in patients with AS is better than that of adalimumab, which is beneficial to improve the spinal function of patients, shorten the morning rigor time, promote blood circulation, reduce inflammatory factors, and no obvious adverse reactions were observed.
  • Review
    ZHANG Wenjing, ZHU Weihong
    Chinese And Foreign Medical Research. 2025, 23(9): 181-184. https://doi.org/10.14033/j.cnki.cfmr.2025.09.048
    Patients with overactive bladder experience a significant impact on quality of life due to urinary control issues, and may even develop long-term complications. The efficacy of conventional Western medicine treatments is not satisfactory. This article collected, organized, and analyzed literature on the treatment of overactive bladder with traditional Chinese external therapy methods from the China National Knowledge Infrastructure database from 2012 to 2024. It was found that methods such as moxibustion, acupoint application, acupuncture, catgut embedding at acupoints, massage, herbal foot baths, fire dragon therapy, acupoint massage, and auricular therapy all have significant therapeutic effects on overactive bladder. Most of these methods are characterized by relatively stable long-term efficacy and few adverse reactions. The article discusses the current research status of traditional Chinese external therapy methods in treating overactive bladder, guides clinical treatment, and explores future research directions.
  • Review
    DING Jiaqin, LIU Qiujiang
    Chinese And Foreign Medical Research. 2025, 23(10): 177-180. https://doi.org/10.14033/j.cnki.cfmr.2025.10.047
    Mixed hemorrhoids is a common disease in anorectal diseases. Surgery is an important treatment for mixed hemorrhoids. However, the occurrence of many postoperative complications brings great pain to patients, so the treatment of postoperative complications is the focus of current treatment of anorectal diseases. This paper summarizes the treatment methods of traditional Chinese and western medicine for postoperative edema, pain and anal distention of mixed hemorrhoids in recent years. Traditional Chinese medicine includes internal treatment, external treatment and acupuncture treatment, while western medicine includes analgesia, circulation improvement and anti-inflammatory treatment. With the help of the combination of traditional Chinese and western medicine, we can give full play to their respective advantages and reduce the occurrence of adverse reactions. This article reviews the pathogenesis and treatment progress of postoperative edema, pain and anal distention of mixed hemorrhoids.
  • Synthetic medicine
    WU Chengcong
    Chinese And Foreign Medical Research. 2025, 23(12): 161-164. https://doi.org/10.14033/j.cnki.cfmr.2025.12.042
    Objective: To explore the application value of flexible ureteroscope combined with flexible flexible negative pressure ureteric sheath in the treatment of kidney stones. Method: A total of 180 patients with kidney stones admitted to the Sixth Hospital of Guiyang City from June 2022 to May 2023 were selected for this study. After numbering them according to the admission order, they were randomly divided into two groups with 90 cases each by drawing lots. In the control group, flexible ureteroscope lithotripsy (FURL) was performed with a non-flexible ureteral guide sheath. Observation group was treated with FURL, ureteral access sheath (FURS). After treatment, the surgical quality, general indexes, pain degree, complications and quality of life of the two groups were compared. Result: The stone clearance rate of the observation group was 95.56% (86/90), and that of the control group was 85.56% (77/90). The stone clearance rate of the observation group was significantly higher than that of the control group, and the difference was statistically significant (P<0.05). The indexes of intraoperative blood loss and hospital stay in the observation group were lower than those in the control group, and the difference was statistically significant (P<0.05). Before surgery, there was no significant difference in visual analogue scale (VAS) between the two groups (P>0.05). The observation group was lower than the control group 1 d and 2 d after operation, and the difference was statistically significant (P<0.05). The complication rate of urinary tract infection in the observation group was lower than that in the control group, the difference was statistically significant (P<0.05). There was no significant difference in quality of life scores between the two groups before operation (P>0.05). The score of quality of life in the observation group was higher than that in the control group, and the difference was statistically significant (P<0.05). Conclusion: The use of FURL and FURS can improve the surgical efficiency, facilitate the removal of stones, improve the surgical quality, shorten the operation time, reduce the surgical trauma, facilitate the postoperative rehabilitation of patients, reduce the pain degree of patients, and improve the life quality of patients.
  • Article
    ZHU Jieqiong, LIAO Feiwen
    Chinese And Foreign Medical Research. 2025, 23(12): 21-24. https://doi.org/10.14033/j.cnki.cfmr.2025.12.006
    Objective: To investigate the therapeutic effect of sertraline combined with repetitive transcranial magnetic stimulation (rTMS) on adolescent depression and its effect on cognitive function. Method: A total of 86 adolescent patients with depression admittted to the Second Affliated Hospital of Hubei University of Science and Technology from January 2022 to June 2023 were selected as the study objects, and they were randomly divided into control group and observation group, with 43 cases in each group. The control group was treated with sertraline alone, and the observation group was treated with sertraline combined with rTMS. Both groups were treated for 4 weeks. The efficacy of the two groups was evaluated, and the scores of 17 items of Hamilton Depression Scale (HAMD-17), Symptom Checklist 90 (SCL-90), Montreal Cognitive Assessment Scale (MoCA), Social Disability Screening Schedule (SDSS) and serum 5-hydroxytryptamine (5-HT) and norepinephrine (NE) levels were compared between the two groups. Result: The total effective rate of observation group was higher than that of control group, and the difference was statistically significant (P<0.05). After treatment, HAMD-17 scores, SCL-90 scores and SDSS scores in observation group were lower than those in control group (P<0.05). The MoCA score of the observation group was higher than that of the control group, and the difference was statistically significant (P<0.05). After treatment, the levels of 5-HT and NE in the observation group were higher than those in the control group, and the difference was statistically significant (P<0.05). Conclusion: rTMS combined with sertraline is effective in the treatment of adolescent depression, which can achieve effective symptom relief and cognitive function improvemen, up-regulation of 5-HT and NE expression may be one of its mechanisms.
  • Article
    CHEN Yuting
    Chinese And Foreign Medical Research. 2025, 23(12): 6-9. https://doi.org/10.14033/j.cnki.cfmr.2025.12.002
    Objective: To explore the effect of Huanglian Wendan Decoction on blood glucose level and sleep quality in type 2 diabetes (T2DM) patients with insomnia. Method: A total of 98 T2DM patients with insomnia treated in Chengxiang District Hospital of Putian City from January 2020 to January 2023 were selected as the study objects and divided into control group and observation group by radom number table, with 49 cases in each group. Both groups were given routine hypoglycemic regimen. The control group was given Esazolam orally, while the observation group was given Huanglian Wendan Decoction plus or less on the basis of control group. The clinical efficacy, blood glucose level, neurotransmitter level and sleep quality of the two groups were compared. Result: The total effective rate of the observation group higher than that of control group (P<0.05). After treatment, the levels of Fasting Plasma Glucose (FPG) and 2-hour postprandial blood glucose (2-hour PG) decreased in both groups, and the observation group had lower levels of FPG and 2-hour PG (P<0.05). After treatment, the levels of BDNF and 5-HT increased in both groups, while the levels of Norepinephrine (NE) decreased. The observation group showed better improvement in Brain-Derived Neurotrophic Factor (BDNF), 5-Hydroxytryptamine (5-HT), and NE (P<0.05). Both groups showed a decrease in Pittsburg Sleep Quality Index (PSQI) scores after treatment, with the observation group having a lower PSQI score (P<0.05). Conclusion: Huanglian Wendan Decoction can reduce blood sugar, regulate neurotransmitter levels, improve sleep quality, and enhance treatment efficacy in patients with T2DM and insomnia.
  • Clinical practice
    JIANG Yan, WANG Xiaoqin
    Chinese And Foreign Medical Research. 2025, 23(9): 38-41. https://doi.org/10.14033/j.cnki.cfmr.2025.09.011
    Objective: To explore the clinical effect of Yinhu Ganmao powder patch on acute upper respiratory tract infection in children. Method: Sixty children with acute upper respiratory tract infection admitted to the Affiliated Hospital of Zunyi Medical University from May 2022 to November 2022 were selected as the study objects. The patients were divided into observation group and control group by systematic randomization, with 30 cases in each group. The control group received conventional oral treatment, and the observation group received Yinhu Ganmao powder patch on the basis of conventional treatment. The main disease score, secondary disease score, symptom change time, clinical efficacy, symptom score and incidence of adverse reactions were compared between the two groups. Result: After treatment, the disappearance time of clinical symptoms in the observation group was shorter than that in the control group, and the difference was statistically significant (P<0.05). The effective rate of treatment in observation group was higher than that in control group, and the difference was statistically significant (P<0.05). Symptom score of observation group was lower than control group, and the difference was statistically significant (P<0.05). The incidence of adverse events in observation group was lower than that in control group, and the difference was statistically significant (P<0.05). Conclusion: The use of Yinhu Ganmao powder patch in the treatment of acute upper respiratory tract infection in children can improve the clinical symptoms, shorten the course of the disease, reduce the symptom score, and no adverse reactions.
  • Article
    GUO Liqiang, ZHANG Fang
    Chinese And Foreign Medical Research. 2025, 23(12): 17-20. https://doi.org/10.14033/j.cnki.cfmr.2025.12.005
    Objective: To explore the effect of Feilike mixture combined with budesonide in the treatment of acute bronchitis. Method: 100 patients with acute bronchitis admitted to Shangzhou Jinghe Nursing Hospital of Shangluo from February 2022 to December 2023 were selected as the study objects and randomly divided into observation group and control group, with 50 cases in each group. Control group received budesonide treatment, observation group combined with Feilike mixture. Symptom improvement time, lung function, inflammatory factors, immune function and adverse reactions were observed in the two groups. Result: Symptom improvement time of observation group was shorter than control group, and the difference was statistically significant (P<0.05). On the first day before treatment, there was no significant difference in lung function index inflammatory factors and immune function between the two groups (P>0.05). 15 days after treatment, the pulmonary function index of observation group was higher than that of control group, and the inflammatory factors and immune function were lower than that of control group, with statistical significance (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion: Feilike Mixture combined with budesonide in the treatment of acute bronchitis can reduce the time of symptom improvement, enhance lung function and reduce inflammatory factors, with high safety and remarkable effect.
  • Synthetic medicine
    WU Shihao, REN Lanxian
    Chinese And Foreign Medical Research. 2025, 23(22): 150-153. https://doi.org/10.14033/j.cnki.cfmr.2025.22.039
    Objective: To investigate the clinical effect of Montelukast sodium combined with Yupingfeng granules in the treatment of allergic rhinitis in children. Method: A cohort of 100 pediatric patients diagnosed with allergic rhinitis was enrolled from Yangjiang Maternal and Child Health Hospital from April 2023 to April 2024. Participants were randomly allocated via a random number table into two groups (n=50 each): control group receiving 0.9% saline nasal irrigation combined with montelukast sodium monotherapy, and research group receiving 0.9% saline nasal irrigation plus a combined regimen of montelukast sodium and Yupingfeng granules. Treatment efficacy and safety were evaluated by comparative analysis of Traditional Chinese Medicine (TCM) syndrome scores, inflammatory cytokine levels, and immunoglobulin profiles before and after the intervention period. Result: Baseline assessments indicated comparable TCM syndrome scores and serum levels of interleukin-6 (IL-6), interleukin-17 (IL-17), interleukin-23 (IL-23), immunoglobulin A (IgA), immunoglobulin G (IgG), and immunoglobulin E (IgE) between groups (P>0.05). After treatment, the syndrome score of the study group was significantly lower than that of the control group, and the concentration of pro-inflammatory factors was also lower than that of the control group. The immune function of the study group was significantly improved, manifested as an increase in IgA and IgG levels compared with the control group, while IgE decreased. The difference was statistically significant (P<0.05). The total clinical effective rate of the study group was significantly higher than that of the control group, and the difference was statistically significant (P<0.05). Moreover, no drug-related serious adverse events occurred in either group. Conclusion: The adjunctive use of Yupingfeng granules with montelukast sodium significantly enhances therapeutic outcomes in pediatric allergic rhinitis. This synergistic approach effectively alleviates nasal symptoms (rhinorrhea, congestion) through concurrent suppression of inflammatory mediators and bidirectional immunomodulation, without increasing drug-related risks.
  • Article
    ZHOU Jianxin, MO Suhong, LAN Liu, XU Fan, ZHAO Liang
    Chinese And Foreign Medical Research. 2025, 23(12): 1-5. https://doi.org/10.14033/j.cnki.cfmr.2025.12.001
    Objective: To evaluate the application effect of automatic cardiopulmonary resuscitation (CPR) instrument in adult patients with cardiac arrest and whether it can reduce the ischemic injury of heart, brain and kidney. Method: A total of 84 patients who underwent in the Second Affiliated Hospital of Guangxi University of Science and Technology and Yongfu County People's Hospital from January 1, 2021 to December 31, 2023 were selected as the study objects, 40 patients who were resuscitated by automatic cardiopulmonary resuscitation instrument were selected as the observation group, and 44 patients who underwent hands-free cardiopulmonary resuscitation were selected as the control group. The success rate of resuscitation, vital signs of patients after resuscitation, blood gas analysis results, serum lactate dehydrogenase (LDH), serum creatine kinase (CK), creatine kinase MB (CKMB), serum creatine creatinine (CREA), serum urea (UREA) index and the incidence of complications were observed in both groups. Result: The success rate of resuscitation in the observation group was higher than that in the control group, the difference was statistically significant (P<0.05). The recovery time of spontaneous circulation (ROSC) >24 h in the observation group was higher than that in the control group, and the recovery time of ROSC was earlier than that in the control group, with no statistical significance (P>0.05). There were no significant differences in vital signs, blood gas analysis results, LDH, CK, CKMB, CREA and UREA indexes between the two groups after successful resuscitation (P>0.05). There was no significant difference in complication rates of hemopneumothorax, rib fracture and gastric contents regurgitation between the two groups after resuscitation (P>0.05). Conclusion: Cardiopulmonary resuscitation instrument has a better rescue effect on patients with cardiac arrest, and has good application value in emergency rescue.
  • Synthetic medicine
    CUI Xingfang, ZHAI Hong
    Chinese And Foreign Medical Research. 2025, 23(9): 137-141. https://doi.org/10.14033/j.cnki.cfmr.2025.09.037
    Objective: To explore the clinical effect of superpulse CO2 lattice laser combined with compound glycyrrhizin on patients with vitiligo. Method: A total of 84 patients with vitiligo who were treated in Liupanshui People's Hospital from January 2022 to October 2023 were selected as the study objects and divided into study group and control group by random number table method, with 42 cases in each group. The control group was treated with superpulse CO2 lattice laser, and the study group was treated with superpulse CO2 lattice laser combined with compound glycyrrhizin. After 6 months of intervention, the clinical efficacy of the two groups was observed, and the white spot area, skin recolor rate, immune indexes, inflammatory indexes and the occurrence of adverse reactions were compared between the two groups. Result: The total effective rate of the study group was higher than that of the control group, and the difference was statistically significant (P<0.05). After treatment, the white plaque area of the study group was smaller than that of the control group, the recolor rate of skin lesions was higher than that of the control group, the levels of serum interleukin-17 (IL-17), interleukin-23 (IL-23) and CD8+ were lower than those of the control group, and the levels of CD3+ and CD4+ were higher than those of the control group, with statistical significance (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion: Superpulse CO2 lattice laser combined with compound glycyrrhizin tablets can effectively reduce the patient's white spot area, improve the patient's immune and inflammatory indexes, with high safety and good clinical efficacy.
  • Review
    SHI Yi, QU Yuan
    Chinese And Foreign Medical Research. 2025, 23(9): 170-173. https://doi.org/10.14033/j.cnki.cfmr.2025.09.045
    Abdominal trauma may lead to abdominal infection, which is a serious complication that requires timely diagnosis and treatment. Abdominal trauma includes injuries caused by various reasons, such as car accidents, knife wounds, gunshot wounds, falls, etc. The severity and risk of abdominal infection depend on the nature of the injury and the organs involved. If timely and effective diagnosis and treatment are not obtained in the event of abdominal infection, it can pose a great threat to patients and even lead to death. Therefore, timely diagnosis and subsequent treatment for patients with abdominal trauma combined with abdominal infection are key measures to improve patient prognosis. Based on this, this article provides a research review on the diagnosis and treatment of patients with abdominal trauma combined with abdominal infection, aiming to provide clinical reference for the diagnosis and treatment of abdominal trauma combined with abdominal infection.
  • Clinical practice
    LI Honglin, ZHAO Li
    Chinese And Foreign Medical Research. 2025, 23(12): 41-44. https://doi.org/10.14033/j.cnki.cfmr.2025.12.011
    Objective: To explore the clinical effect of cindilimumab combined with albumin-binding paclitaxel and nedaplatin in cervical cancer patients. Method: total of 82 patients with cervical cancer admitted to Jinshazhou Hospital of Guangzhou University of Chinese Medicine from April 2023 to April 2024 were selected as the study objects, and were divided into experimental group (n=41) and control group (n=41) by random number table method. The treatment regimen of the control group was albumin-bound paclitaxel combined with nedaplatin, and the treatment regimen of the experimental group was sindelizumab combined with albumin-bound paclitaxel and nedaplatin. The short-term efficacy, long-term efficacy, levels of inflammatory factors and immune indexes, levels of serum tumor markers, and incidence of adverse reactions were compared between the two groups. Result: The disease remission rate and disease control rate in the test group were higher than those in the control group (P<0.05). Progression-free survival and overall survival in the test group were higher than those in the control group (P<0.05). The level of squamous cell carcinoma antigen (SCC), platelet-to-lymphocyte ratio (PLR) levels were lower in the control group, lymphocyte to monocyte ratio (LMR) levels were higher than the control group (P<0.05). Comparison of the serum tumor marker levels, the post-treatment test group was lower than the control group (P<0.05). After treatment, the incidence of adverse effects, there was no significant difference between the two groups (P>0.05). Conclusion: In cervical cancer patients, cindilizumab and albumin-binding paclitaxel and nedaplatin have significant short-term and long-term effects, which can relieve inflammation, regulate immune function, reduce serum tumor markers, and have high therapeutic safety.
  • Clinical practice
    ZHANG Jianping, BIAN Weigang, CHEN Yan
    Chinese And Foreign Medical Research. 2025, 23(12): 61-64. https://doi.org/10.14033/j.cnki.cfmr.2025.12.016
    Objective: To investigate the effect of cindilizumab combined with chemotherapy on advanced gastric cancer and the changes of tumor indexes. Method: According to random number table method, 86 patients with gastric cancer treated in Yancheng NO.1 People's Hospital from February 2022 to January 2024 were divided into control group and monoclonal antibody group, with 43 cases in each group. The monoclonal antibody group was treated with Sintillizumab combined with chemotherapy, while the control group was treated with oxaliplatin plus capecitabine (XELOX). After 6 cycles of treatment, the safety, therapeutic effect, tumor indexes, serum transforming growth factor-β1 (TGF-β1) and vascular endothelial growth factor (VEGF) levels were compared between the two groups. Result: There was no statistically significant difference in the incidence of toxic side effects between the two groups (P>0.05). After treatment, the objective efficacy of the monoclonal antibody group was higher than that of the control group, and the difference was statistically significant (P<0.05). After treatment, the levels of carcinoembryonic antigen, carbohydrate antigen 242, carbohydrate antigen 724, glycoprotein antigen 50 and carbohydrate antigen 199 in monoclonal antibody group were lower than those in control group, with statistical significance (P<0.05). After treatment, the levels of TGF-β1 and VEGF in monoclonal antibody group were lower than those in control group, and the differences were statistically significant (P<0.05). Conclusion: The combination of Sindilizumab and XELOX regimen in advanced gastric cancer patients can improve the therapeutic effect, regulate the level of tumor markers, serum TGF-β1 and VEGF levels, and has high safety.
  • Clinical practice
    ZHANG Zhe, SU Zhiwei
    Chinese And Foreign Medical Research. 2025, 23(12): 25-29. https://doi.org/10.14033/j.cnki.cfmr.2025.12.007
    Objective: To analyze the therapeutic effect of Huanglian Jiedu Decoction on cognitive dysfunction and clinical symptoms of Parkinson's disease. Method: 60 with Parkinson's disease cognitive dysfunction admitted to Hebei Hospital of Traditional Chinese Medicine from January 2020 to June 2022 were selected as the study objects and divided intoa control group and an observation group according to random number table method. 30 patients in the control group were treated with Western medicine, and 30 patients in the observation group were treated with Huanglian Jiadu Decoction on the basis of control group. After 4 weeks, the clinical efficacy, clinical symptoms of Parkinson's disease, cognitive function, constipation degree, emotional state and sleep quality of the two groups were compared. Result: After treatment, the total effective rate in the observation group was higher than that in the control group, and the difference was statistically significant (P<0.05). The Unified Parkinson's Disease Scale (UPDRS) score the observation group was lower than that points of the control group, and the difference was statistically significant (P<0.05). The scores of the Montreal Cognitive Assessment Scale (MoCA) and the Simple Mental State Scale (MMSE) in the observation group were higher than those in the control group [(23.14±4.23) points and (24.20±3.09) points], and the difference was statistically significant (P<0.05). In the observation group, the scores of Wexner Constipation Rating Scale (Wexner), Hamilton Depression Scale (HAMD) and Hamilton Anxiety Scale (HAMA) were lower than those in the control group, while the scores of Parkinson's Disease Sleep Scale (PDSS) was higher than the control group, and the difference was statistically significant (P<0.05). Conclusion: Huanglian Jiedu Decoction can achieve significant results in the treatment of cognitive dysfunction in Parkinson's disease, which can not only improve the clinical efficacy of patients, alleviate clinical symptoms of Parkinson's disease, improve cognitive function, but also promote the improvement of constipation, emotional state, as well as further improve the quality of sleep.
  • Clinical practice
    CHEN Qiaoling
    Chinese And Foreign Medical Research. 2025, 23(11): 21-24. https://doi.org/10.14033/j.cnki.cfmr.2025.11.006
    Objective: To study the clinical effect of pain point point press combined with stretching in the treatment of lumbar muscle strain. Method: A total of 90 patients with lumbar muscle strain who admitted to Longyan People's Hospital from February 2023 to April 2024 were selected as the study objects, they were divided into the acupuncture group (acupuncture therapy) and the massage group (massage therapy) and the pain point therapy combined group (pain point point press combined with stretching therapy) according to different treatment methods, with 30 cases in each group. The clinical efficacy, recurrence rate after 3 months and 6 months of treatment, the degree of psoas muscle pain before and after treatment [visual analogue scale (VAS)], lumbar dysfunction [Roland-Morris disability questionnaire (RDQ)] and range of lumbar motion among three groups were observed and compared. Result: The total clinical effective rate of the pain point therapy combined group was higher than those of the acupuncture group and the massage group, and the differences were statistically significant (P<0.05); the recurrence rate of the pain point therapy combined group after 3 months and 6 months of treatment were lower than those of the acupuncture group and the massage group, and the differences were statistically significant (P<0.05); the VAS score and RDQ score of the pain point therapy combined group after treatment were lower than those of the acupuncture group and the massage group, and the lumbar range of motion (lumbar extension, flexion and lateral flexion) were greater than those of the acupuncture group and the massage group, the differences were statistically significant (P<0.05). Conclusion: Pain point point press combined with stretching in the treatment of lumbar muscle strain can effectively alleviate the degree of lumbar muscle pain, improve lumbar dysfunction, increase the range of lumbar activity, and reduce the risk of disease recurrence, and the clinical effect is significant.
  • Clinical practice
    FAN Menghao
    Chinese And Foreign Medical Research. 2025, 23(9): 34-37. https://doi.org/10.14033/j.cnki.cfmr.2025.09.010
    Objective: To explore the effects of blood flow restriction therapy combined with Mulligan dynamic joint mobilization on pain, exercise fear, and functional recovery in patients with knee osteoarthritis. Method: A total of 120 patients with knee osteoarthritis who were treated in Shanxi Provincial Integrated TCM and WM Hospital from January 2022 to June 2023 were selected as the study objects, and were divided into combination group, blood flow restriction therapy group and dynamic joint loosening group according to random number table method, with 40 cases in each group. The dynamic joint loosening group received Mulligan dynamic joint loosening, the blood flow restriction therapy group received blood flow restriction training, and the combined group received both dynamic joint loosening and blood flow restriction training for a total of 8 weeks. Visual Analog Scale (VAS), Tampa Scale for Kinesiophobia (TSK), Western Ontario and McMaster University Rating Scale (WOMAC), Berg Balance Scale (BBS), standing up and Sitting test (TUGT) and 10-meter walking test were compared before and after the intervention. Result: After intervention, VAS score, TSK score, WOMAC score, TUGT score and 10-meter walking test were all decreased in the three groups, and BBS score was increased, and the difference was statistically significant (P<0.05). After intervention, compared with the blood flow restriction group and dynamic joint loosening group, VAS score, TSK score, WOMAC score, TUGT score and 10-meter walking test were lower in the combined group. And BBS score was higher, with statistical significance (P<0.05). Conclusion: The combination of flow restriction therapy and Mulligan dynamic joint loosening or single method can improve pain, exercise fear and functional recovery in patients with knee osteoarthritis, but the combined effect is more obvious.
  • Review
    WANG Wenzai, CHEN Tingting, CHEN Xujun, CHEN Lianghua, ZHANG Fen, HUANG Fazhang, LIN Yuan
    Chinese And Foreign Medical Research. 2025, 23(12): 181-184. https://doi.org/10.14033/j.cnki.cfmr.2025.12.047
    Spasm of paralyzed limbs after stroke is a common sequelae after stroke, which affects the functional reconstruction of the affected limbs, and significantly reduces the quality of life and rehabilitation confidence of patients. Studies have shown that acupuncture therapy can improve the spasticity of paralyzed limbs after stroke, and it is easy to operate and has no obvious adverse reactions. This article collected the acupuncture and moxibustion methods for the treatment of limb spastic paralysis after stroke in recent years, and summarized the scalp acupuncture, abdominal acupuncture, umbilical acupuncture, fire acupuncture, electric acupuncture, bloodletting therapy, moxibustion therapy, needle-knife therapy, etc., to provide some reference for acupuncture treatment of spastic paralysis after stroke.
  • Review
    SHENG Ruxin, MA Zhong
    Chinese And Foreign Medical Research. 2025, 23(10): 181-184. https://doi.org/10.14033/j.cnki.cfmr.2025.10.048
    Cervical spondylotic radiculopathy is a common chronic degenerative disease, mainly manifested as neck pain, stiffness and limited movement. With the rapid development of modern society, the incidence of cervical spondylotic radiculopathy has increased year by year because of long-term fixed posture or bending over the desk. Acupuncture and moxibustion, as a traditional Chinese medicine treatment method, has been widely concerned because of its remarkable curative effect and small side effects. Through literature retrieval, this paper summarizes the research progress of acupuncture and moxibustion in the treatment of cervical spondylotic radiculopathy of Qi stagnation and blood stasis in recent five years, in order to provide new ideas and clues for acupuncture and moxibustion in the treatment of cervical spondylotic radiculopathy and promote its scientific and standardized development.
  • Review
    KANG Yimin
    Chinese And Foreign Medical Research. 2025, 23(10): 171-173. https://doi.org/10.14033/j.cnki.cfmr.2025.10.045
    Ultrasound-guided fine-needle aspiration cytology (US-FNAC) is one of the most commonly used diagnostic methods for differentiating benign and malignant thyroid nodules in clinical practice, and its cytological examination results are also the gold standard for clinical diagnosis. The procedure includes many steps, such as accurate judgment of thyroid nodule location under ultrasound guidance, selection of puncture path, selection of puncture needle, puncture technique and cytology examination, reasonable and accurate operation of each step has a certain impact on the result of diagnosis, which also leads to some limitations of examination. Proper understanding of US-FNAC can make the clinical application of this technique better develop and improve the accuracy of benign and malignant diagnosis of thyroid nodules. This article reviews the application status and limitations of US-FNAC in thyroid nodules, in order to provide strong theoretical guidance for clinical practice.
  • Synthetic medicine
    WANG Yanjun
    Chinese And Foreign Medical Research. 2025, 23(10): 151-154. https://doi.org/10.14033/j.cnki.cfmr.2025.10.040
    Objective: To investigate the effect of Chinese medicine encapsulation intervention of rhubarb mirabilite in parturients after cesarean section. Method: A total of 100 women who underwent cesarean section in Liupanshui City Maternal and Child Health Care Hospital from June to December 2023 were selected, they were randomly divided into two groups, 50 cases in each group. The control group received routine intervention, and the observation group was added with Chinese medicine encapsulation intervention of rhubarb mirabilite. The incision pain, swelling degree, incision healing status, incision recovery time, comfort level, and inflammation level were compared between the two groups. Result: After intervention, the pain score and swelling degree score of the observation group were lower than those of the control group, and the incision healing was better than that of the control group, the differences were statistically significant (P<0.05). The time of redness, induration and incision healing in observation group was shorter than that in control group, and the differences were statistically significant (P<0.05). The score dimensions and total scores of the simplified comfort status scale after intervention in the observation group were higher than those in the control group, and the differences were statistically significant (P<0.05). The inflammation level in the observation group was lower than that in the control group after intervention, and the differences were statistically significant (P<0.05). Conclusion: The Chinese medicine encapsulation intervention of rhubarb mirabilite can accelerate maternal incision healing, reduce incision pain and swelling, reduce inflammation level, and improve maternal comfort.
  • Review
    ZHANG Liran, ZHANG Ziya, HAN Xiangyu
    Chinese And Foreign Medical Research. 2025, 23(12): 176-180. https://doi.org/10.14033/j.cnki.cfmr.2025.12.046
    Myocardial Infarction (MI) and Aortic Dissection (AD) are two common acute cardiovascular diseases that manifest as acute chest pain. Recent studies have shown that inflammatory response is closely related to the occurrence and development of MI and AD, and the number of some inflammatory cells in peripheral blood, such as neutrophils, lymphocytes, platelets and monocytes, have varying degrees of change in both diseases. The article reviews the role of inflammatory derived indicators such as neutrophils/lymphocytes (NLR), platelets/lymphocytes (PLR), monocytes/high-density lipoprotein (MHR), and systemic immunoinflammatory index (SII) in the two diseases, with a view to providing new diagnosis and treatment ideas for early identification of MI and AD.
  • Experience
    YANG Ke
    Chinese And Foreign Medical Research. 2025, 23(12): 126-129. https://doi.org/10.14033/j.cnki.cfmr.2025.12.033
    Objective: To analyze the clinical value of the treatment of anal fistula (AF) through intersphincter approach (hereinafter referred to as release) and incision drainage. Method: Clinical data of 126 patients with anal fistula admitted to Xiamen Changgeng Hospital from November 2022 to December 2023 was selected and retrospectively analyzed. They were divided into the control group and the observation group according to the differences in surgical methods. The control group (n=63 cases) received incision and drainage, and the observation group (n=63 cases) received loose drainage. The surgical and prognostic indexes, complications, Visual Analogue Scale (VAS) scores at different time points, anal function before and 3 months after surgery, and serum inflammatory factor levels before and 1 day after surgery were compared between the two groups. Result: Compared with the control group, the operation, postoperative hematochezia, wound healing, pus shedding and hospital stay in the observation group were shorter, and the difference was statistically significant (P<0.05). The results of repeated measurement variance Mauchly’ s sphericity test showed that the VAS scores of the two groups at different time points were consistent with the sphericity test, and the results did not need to be corrected by Greenhouse-Geisser method. According to the main effect analysis of measurement time, VAS scores of the two groups increased first and then decreased 1 h, 1 d and 7 d after surgery, with statistical significance (P<0.05). The main effect analysis of the groups showed that the VAS scores of the observation group were lower than those of the control group 1 d and 7 d after surgery, and the difference was statistically significant (P<0.05). Compared with the control group, the serum levels of Interleukin-6 (IL-6), Tumor Necrosis Factor-α(TNF-α), Interleukin-8 (IL-8) and Wexner incontinence score in the observation group were lower 1 day after surgery, and the mean anal venous pressure and mean maximum anal constriction pressure were higher 3 months after surgery, with statistical significance (P<0.05). The complication rate of observation group (3.7%) was lower than that of control group (17.46%), and the difference was statistically significant (P<0.05). Conclusion: The treatment of AF can effectively shorten the operation time, reduce pain, reduce inflammatory stress, promote postoperative recovery, improve the anal function of patients with few complications.
  • Experience
    YANG Libai, LIU Yongtao, LIU Meizhang, ZHANG Chuqiong
    Chinese And Foreign Medical Research. 2025, 23(12): 141-144. https://doi.org/10.14033/j.cnki.cfmr.2025.12.037
    Objective: To analyze the effect of warm acupuncture and moxibustion at four abdominal points combined with acupuncture based on meridian theory on facial nerve muscle strength and function in patients with intractable facial paralysis. Method: A total of 80 patients with intractable facial paralysis treated in the outpatient department of Huai’an Hospital of Traditional Chinese Medicine from January 2021 to January 2024 were selected as the study objects and divided into control group and observation group according to random number table method, with 40 cases in each group. The control group was treated with conventional acupuncture, and the observation group was treated with abdominal four-point warm acupuncture combined with theoretical acupuncture. The clinical effect, facial nerve muscle strength, facial nerve function, body function and social life ability of the two groups were compared. Result: The total effective rate of the observation group was higher than that of the control group, and the House-Brackmann (H-B) facial nerve function evaluation grading standard was better than that of the control group, and the difference was statistically significant (P<0.05). After treatment, Sunnybrook facial nerve rating system score and Facial Disability Index Physical (FDIP) score of observation group were higher than those of control group, and the difference was statistically significant (P<0.05). The social function (FDIS) score of observation group was lower than that of control group, and the difference was statistically significant (P<0.05). Conclusion: The combination of warm acupuncture and moxibustion at abdominal four points and acupuncture at meridian theory can effectively improve the facial nerve muscle strength and function of patients with intractable facial paralysis, help to improve the physical function and social life ability, and have certain application value, which is worthy of clinical reference.
  • Clinical practice
    YING Lintong, XIE Xiufang, LI Xiujuan
    Chinese And Foreign Medical Research. 2025, 23(12): 64-67. https://doi.org/10.14033/j.cnki.cfmr.2025.12.017
    Objective: To evaluate the clinical efficacy of deep needling of Shaoyang meridian acupoints combined with modified Cong'er Ximing Tang in the treatment of refractory sudden sensorineural hearing loss (RSSNHL). Method: 100 patients with RSSNHL admitted to Ningde Hospital of Traditional Chinese Medicine from November 2021 to December 2023 were selected as the study objects and randomly divided into combination group and control group, with 50 cases in each group. The combined group was treated with Shaoyang meridian acupoints and acupoints combined with Cong'er Ximing Tang, and the control group was treated with Cong'er Ximing Tang. Hearing improvement, tinnitus score, psychological state, TCM syndrome score, quality of life and adverse reactions were compared between the two groups. Result: After treatment, the hearing threshold and tinnitus score of the combined group were lower than those of the control group, and the differences were statistically significant (P<0.05). The anxiety and depression scores of the combined group were lower than those of the control group after treatment, and the difference was statistically significant (P<0.05). After treatment, the TCM syndrome score of the combined group was lower than that of the control group, and the quality of life score was higher than that of the control group, and the difference was statistically significant (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion: The combination of deep needling of Shaoyang meridian acupoints and modified Cong'er Ximing Tang has significant therapeutic effects on RSSNHL, which can effectively improve patients' clinical symptoms and psychological status, promote the improvement of quality of life, and have high safety.
  • Clinical practice
    WANG Yajian
    Chinese And Foreign Medical Research. 2025, 23(9): 52-55. https://doi.org/10.14033/j.cnki.cfmr.2025.09.015
    Objective: To analyze the clinical efficacy and impact on renal function of the combined use of cyclophosphamide and glucocorticoids in the treatment of nephrotic syndrome (NS) patients. Method: A total of 86 patients with NS treated in Liupanshui People's Hospital from July 2020 to August 2024 were selected as the study objects. They were divided into control group and observation group by stratified drawing method, with 43 cases in each group. The control group was treated with glucocorticoid, and the observation group was treated with cyclophosphamide combined with glucocorticoid. The therapeutic effect, renal function index, blood lipid index, toxicity and side effects were compared between the two groups. Result: The total clinical effective rate of the observation group was better than that of the control group, and the difference was statistically significant (P<0.05). After treatment, compared with control group, serum albumin (ALB) content and serum creatinine level in observation group were higher, blood urea nitrogen (BUN) concentration and 24 h urinary protein quantitative level were lower, and the differences were statistically significant (P<0.05). After treatment, the levels of triglyceride (TG), total cholesterol (TC)and low density lipoprotein cholesterol (LDL-C) in the observation group were lower than those in the control group, and the difference was statistically significant (P<0.05). There was no significant difference in the incidence of side effects between the two groups (P>0.05). Conclusion: Combined treatment with cyclophosphamide and glucocorticoid can improve the clinical efficacy of patients with nephrotic syndrome, improve renal function and lipid indexes, and do not increase the incidence of side effects.
  • Review
    LIU Guihong, LI Weibo, LIN Huixia, FENG Shuangxi, HUANG Fang
    Chinese And Foreign Medical Research. 2025, 23(10): 174-176. https://doi.org/10.14033/j.cnki.cfmr.2025.10.046
    Transcranial magnetic stimulation (TMS), as a non-invasive neuromodulation technology, has the advantages of being painless, non-invasive, safe, and with few side effects, which provides a new option for the treatment of neurological and psychiatric diseases. With the continuous development and improvement of the technology, TMS has been widely used in the treatment and research of neurological diseases and psychiatric disorders. This paper presents a review of the latest research progress of TMS in the rehabilitation of motor function of children with spastic cerebral palsy, it aims to provide a reference for clinical work.
  • Synthetic medicine
    ZHAO Changying, ZHANG Dandan
    Chinese And Foreign Medical Research. 2025, 23(12): 169-172. https://doi.org/10.14033/j.cnki.cfmr.2025.12.044
    Objective: To explore the therapeutic effect of transcutaneous acupoint electrical stimulation of Ren Du vessels combined with bridge exercise in patients with urinary incontinence after stroke. Method: From January 2022 to June 2023, 60 patients with urinary incontinence after stroke admitted to Guangdong Work Injury Rehabilitation Hospital were selected as the study objects and divided into two groups by envelope method, with 30 cases in each group. All the patients were treated with routine methods. The control group was combined with bridge exercise intervention. The observation group was combined with transcutaneous electrical stimulation of Ren Du acupoints on the basis of the control group. Both groups completed 4 weeks of treatment. The urodynamics, overactive bladder overactive symptom score (OABSS) and pelvic floor muscle strength were compared between the two groups. Result: After the intervention, the urodynamics of the two groups was improved. The voiding filling sensation (Vfs) and maximum bladder volume (Vmax) of the observation group were higher than those of the control group (P<0.05). The maximum detrusor pressure level was lower than that of the control group (P<0.05). After the intervention, the OABSS scores of the two groups decreased. The scores of daytime urinary frequency, nighttime urinary frequency, urgency and urgent urinary incontinence in the observation group were lower than those in the control group (P<0.05). After the intervention, the pelvic floor muscle strength of the two groups was improved. The number of cases of grade 3, grade 4 and grade 5 in the observation group was higher than that in the control group (P<0.05). Conclusion: Percutaneous Ren Du acupoint electrical stimulation combined with bridge exercise can improve the urodynamic level of patients with urinary incontinence after stroke, help to reduce the score of overactive bladder symptoms and improve pelvic floor muscle strength.
  • Article
    YUE Bingqing, ZHOU Wentao
    Chinese And Foreign Medical Research. 2025, 23(20): 1-4. https://doi.org/10.14033/j.cnki.cfmr.2025.20.001
    Objective: To investigate the effect of Weisu Granules based on four joint program in the treatment of gastric mucosal lesions in patients with Helicobacter pylori (HP) infection complicated with atrophic gastritis. Method: A total of 90 patients with HP infection complicated with atrophic gastritis admitted to Wuxue Hospital of Traditional Chinese Medicine from April 2022 to April 2023 were selected as the research objects. They were divided into the Western medicine group, the traditional Chinese medicine group and the integrated traditional Chinese and Western medicine group according to the random number table method, with 30 cases in each group. The Western medicine group was treated with the quadruple therapy, the traditional Chinese medicine group was treated with Weisu Granules, and the integrated traditional Chinese and Western medicine group was treated with the quadruple therapy combined with Weisu Granules. The levels of gastrin (GAS), motilin (MTL), and gastrin-17 (G-17), as well as the TCM syndrome scores were compared among the three groups. Levels of inflammatory factors [C-reactive protein (CRP), interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α)]. Result: After treatment, the GAS and MTL in the integrated traditional Chinese and Western medicine group were lower than those in the Western medicine group and the traditional Chinese medicine group, while the G-17 level was higher than that in the Western medicine group and the traditional Chinese medicine group, and the differences were statistically significant (P<0.05). The TCM syndrome scores (belching, acid reflux, abdominal distension and abdominal pain) in the integrated Chinese and Western medicine group were lower than those in the Western medicine group and the traditional Chinese medicine group, and the difference was statistically significant (P<0.05). The levels of CRP, IL-6 and TNF-α in the integrated traditional Chinese and Western medicine group were lower than those in the Western medicine group and the traditional Chinese medicine group, and the difference was statistically significant (P<0.05). Conclusion: Gaisu Granules have a significant effect in the treatment of patients with HP infection complicated with atrophic gastritis. It can improve the clinical gastric discomfort symptoms of patients, effectively regulate the levels of gastrointestinal hormones, promote the repair of gastric mucosa, and reduce the inflammatory response.
  • Experience
    HAO Kaimin, TIAN Zhaoxia,HAO Zhihong
    Chinese And Foreign Medical Research. 2025, 23(12): 122-125. https://doi.org/10.14033/j.cnki.cfmr.2025.12.032
    Objective: To investigate the effect of targeted nursing based on the Health-Promoting Lifestyle Profile (HPLP) on medication adherence and health behavior of elderly hypertensive patients. Method: From January 2021 to December 2023, 150 hypertensive patients admitted to Fenyang People's Hospital were selected as the study objects, and divided into the control group and the study group according to the odd/even number grouping method, with 75 cases in each group. The patients of control group received routine nursing and follow-up, while the patients of study group received targeted nursing based on the HPLP. Medication adherence, health behavior, and self-efficacy of the two groups were compared. Result: After 6 months of follow-up, the medication compliance of the study group was significantly better than that of the control group, with statistical significance (P<0.05). The scores of Health Promotion Lifestyle Scale Ⅱ (HPLPⅡ) in the aspects of health responsibility, self-actualization, nutrition, interpersonal relationship, exercise and stress management were increased in the study group, and the scores of the study group were increased more than those of the control group, and the difference was statistically significant (P<0.05). The Self-efficacy to Manage Chronic Disease (SEMCD) scores of both groups were increased, and the increase rate was greater in the study group, with statistical significance (P<0.05). Conclusion: Targeted nursing based on the Health-Promoting Lifestyle Profile is an effective nursing intervention method. It can significantly improve medication adherence, health behavior, and self-efficacy of elderly hypertensive patients..
  • Synthetic medicine
    LI Fangjun, YAN Guanghua
    Chinese And Foreign Medical Research. 2025, 23(12): 145-149. https://doi.org/10.14033/j.cnki.cfmr.2025.12.038
    Objective: To explore the risk factors of viral diarrhea in infants and young children in Zaozhuang City, Shandong Province from 2022 to 2023, and to investigate its pathogenic characteristics. Method: A total of 183 infants and young children with viral diarrhea reported in Zaozhuang City, Shandong Province from January 2022 to December 2023 were included as the observation group, and 183 non viral diarrhea infants and young children during the same period were selected as the control group. A questionnaire survey was conducted on all guardians of the infants and young children, and univariate and multivariate analyses were conducted on the risk factors of viral diarrhea in infants and young children. At the same time, all fecal samples of the affected children will be examined to investigate their pathogenic characteristics. Result: The observation group had a higher proportion of infants and young children who sucked their fingers, had contact with diarrhea patients within 7 days, visited hospitals and clinics within 7 days, taken antibiotics within 7 days, had parents with a high school diploma or below, kept pets, had unpasteurized drinking water, unpasteurized tableware and dairy utensils, separated kitchen knives and utensils, and did not wash their hands before meals compared to the control group (P<0.05). Multivariate analysis showed that finger sucking in infants and young children, contact with diarrhea patients within 7 days, visits to hospitals and clinics within 7 days, use of antibiotics within 7 days, parents' education level of high school or below, and pet ownership were independent risk factors for viral diarrhea in infants and young children. Disinfection of drinking water, tableware and dairy utensils, separation of raw and cooked kitchen knives, and washing hands before meals by feeders/infants were protective factors . Among 183 infants and young children with viral diarrhea, single pathogen infection accounted for 84.15%, with Rotavirus (RV) infection being the most common, followed by Human ca-licivirus (HuCV) and Enteric Adenovirus (EAdV), mixed infection accounted for 15.85%, with RV combined with HuCV being the most common, followed by HuCV combined with Astrovirus (AstV) and RV combined with EAdV. Conclusion: The risk factors for viral diarrhea in infants and young children in this region in the past 2 years include a history of virus contact, antibiotic use, lack of health knowledge among parents, and poor living environment, while good hygiene habits are protective factors. Moreover, the pathogen is mainly rotavirus, and targeted preventive measures should be developed according to the situation in clinical practice.
  • Experience
    FAN Qi, YANG Shunhong
    Chinese And Foreign Medical Research. 2025, 23(12): 133-136. https://doi.org/10.14033/j.cnki.cfmr.2025.12.035
    Objective: To explore the clinical effect of combining probiotics particles and diprogestin in patients with endometriosis (EMS). Method: 58 patients diagnosed with EMS admitted to Anshun Maternal and Child Health Care Hospital from February 2023 to December 2023 were selected as study objects by randomized control method, and were divided into study group (n=29) and control group (n=29) according to the odd-even number of patient records. The control group was treated with dinorgestrel, and the study group was treated with probiotic granules combined with dinorgestrel. The clinical effective rate, sex hormone levels, endometrial thickness, uterine hemodynamic indexes, inflammatory factor levels, and incidence of adverse reactions were compared between the two groups. Result: The clinical effective rate of study group was higher than that of control group, and the difference was statistically significant (P<0.05). After treatment, the levels of sex hormones in the study group were lower than those in the control group, and the difference was statistically significant (P<0.05). After treatment, the endometrial thickness and uterine hemodynamics indexes of the study group were lower than those of the control group, and the differences were statistically significant (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion: The combination of probiotic granules and dinorgestrel in EMS patients has significant therapeutic effect, which can improve sex hormone levels, reduce endometrial thickness and hemodynamic indexes, and has high drug safety.
  • Modern nursing
    XIE Minxia
    Chinese And Foreign Medical Research. 2025, 23(12): 114-117. https://doi.org/10.14033/j.cnki.cfmr.2025.12.030
    Objective: To explore the effect of mechanical vibration sputum expectorant and abdominal breathing training in postoperative nursing patients with cardiovascular disease. Method: 70 Seventy patients with large cardiac vessels admitted to Fujian Medical University Union Hospital from January 2023 to December 2023 were selected as the study objects, and were divided into control group (n=35) and observation group (n=35) by random number table method. The control group was given abdominal breathing training, and the observation group was given mechanical vibration sputum expelling apparatus and abdominal breathing training. The changes of vital signs (RR, PaO2, PaCO2, HR) and expectoration effect (total amount of sputum and difficulty of expectoration) before and after intervention were compared between the two groups. The Kolcaba Simplified Comfort Scale (GCQ) and the incidence of pulmonary infection were measured. Result: After intervention, the PaO2 level in observation group was higher than that in control group, and the PaCO2 level, HR and RR values were lower than those in control group, with statistical significance (P<0.05). The total amount of sputum in the observation group was higher than that in the control group after intervention, and the difference was statistically significant (P<0.05). The phlegm difficulty score of the observation group was lower than that of the control group, and the difference was statistically significant (P<0.05). The comfort level of observation group was higher than that of control group, and the difference was statistically significant (P<0.05). The incidence of pulmonary infection in observation group was lower than that in control group, and the difference was statistically significant (P<0.05). Conclusion: The combined implementation of mechanical vibration expectorant and abdominal breathing training in patients after cardiac and vascular surgery can not only enhance the expectorant effect, but also improve their vital signs, reduce pulmonary infections, and improve patient comfort.
  • Modern nursing
    ZHENG Qin
    Chinese And Foreign Medical Research. 2025, 23(12): 118-121. https://doi.org/10.14033/j.cnki.cfmr.2025.12.031
    Objective: To analyse the effect of balanced fire cupping therapy combined with rehabilitation nursing on the rehabilitation of patients with stroke hemiplegia. Method: Sixty patients with stroke hemiplegia admitted to Huaxi District Hospital of Traditional Chinese Medicine of Guiyang City from January 2023 to January 2024 were selected as the study objects, and were divided into observation group and control group by random number table method, with 30 cases in each group. The control group received rehabilitation nursing, while the observation group added balanced cupping on this basis. The physical function, self-care ability and coordination function were compared between the two groups. Result: After intervention, the physical activity function score and self-care ability rating scale (ADL) score of the observation group were higher than those of the control group, and the difference was statistically significant (P<0.05). After the intervention, the scores upper limb movement, lower limb movement and basic transfer activity in the observation group were higher than those in the control group, while the scores postural and gait abnormalities, limb ataxia and dysarthria were lower than those in the control group, with statistical significance (P<0.05). Conclusion: Balanced fire cupping therapy combined with rehabilitation care can promote the recovery of limb function, improve ataxic coordination and enhance the ability of hemiplegic stroke patients to take care of themselves.
  • Experience
    DENG Xiaomei, ZHENG Luanying, ZHANG Liping, YE Hong
    Chinese And Foreign Medical Research. 2025, 23(12): 129-132. https://doi.org/10.14033/j.cnki.cfmr.2025.12.034
    Objective: To explore the clinical efficacy of Jiawei Kuntai Pill in treating ovarian dysfunction. Method: 68 patients with ovarian dysfunction admitted to Guangzhou Haizhu District Hospital of Traditional Chinese Medicine from February 2024 to May 2024 were selected as the study objects. The patients were randomly divided into a conventional Western medicine group and a modified Kuntai Pill group, with 34 cases in each group. The conventional Western medicine group received routine treatment with Fenmetol, while the modified Kuntai Pill group was treated with modified Kuntai Pill on the basis of conventional treatment. The menstrual status, follicle stimulating hormone (FSH), luteinizing hormone (LH), estradiol (E2), anti Mullerian hormone (AMH), FSH/LH, and traditional Chinese medicine syndrome scores of patients in the two groups were compared before and after treatment. Result: After treatment, the number of antral follicles, menstrual scores, E2 and AMH levels increased in both groups, while FSH, LH, FSH/LH, and traditional Chinese medicine syndrome scores decreased, and the number of antral follicles, menstrual score, E2 and AMH levels in the modified Kuntai Pill group were higher than those in the conventional Western medicine group, while FSH, LH, FSH/LH levels, and TCM syndrome score in the modified Kuntai Pill group were lower than those in the conventional Western medicine group, and the differences were statistically significant (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion: Modified Kuntai Pill can improve the menstrual status and traditional Chinese medicine symptoms of patients with ovarian dysfunction, and regulate their hormone levels.
Highlights
Download
Data Inclusion
Share