[Abstract] Objective: To examine the effectiveness of partner-involved care guided by IFSMT theory on pregnant patients with hypertension. Method: A total of 100 patients with pregnancy-induced hypertension admitted to Yangzhou Maternal and Child Care Service Centre from January 2021 to January 2024 were selected as the study objects and divided into experimental group and control group according to random drawing method, with 50 cases in each group. The control group received routine nursing, and the experimental group received partner participation nursing guided by IFSMT theory. Blood pressure level, psychological and emotional [Fear of Childbirth Scale (CAQ) score, Patient Health Questionnaire Depression Scale (PHQ-9) score, 7-item Generalized Anxiety Disorder Scale (GAD-7) score], self-efficacy [General Self-efficacy Scale (GSES) score], self-management ability [Self-Care Health Management Questionnaire (SQHMP) score], and pregnancy outcomes (preterm birth, cesarean section, postpartum hemorrhage, eclampsia, termination of pregnancy) were compared between the two groups. Result: After intervention, the systolic blood pressure, diastolic blood pressure, CAQ, PHQ-9 and GAD-7 scores of the experimental group were lower than those of the control group, with statistical significance (P<0.05). The GSES scores and SQHMP scores of the experimental group were higher than those of the control group, and the differences were statistically significant (P<0.05). The incidence of preterm birth, cesarean section, postpartum hemorrhage, eclampsia and termination of pregnancy in the experimental group was lower than that in the control group, with statistical significance (P<0.05). Conclusion: The partner participation nursing under the guidance of IFSMT theory can significantly improve the blood pressure control, psychological state, self-efficacy and self-management ability of hypertensive patients during pregnancy, and optimize the pregnancy outcome, which is an effective nursing intervention method.

Polycystic ovary syndrome (PCOS) is a gynecological disease with high incidence of endocrine and metabolic disorders in the reproductive age, its etiology and pathogenesis remain unclear, it may be related to endocrine disorders, insulin resistance, inflammatory factors, intestinal flora, oxidative stress, etc. Traditional Chinese medicine has the unique advantages of high safety and low side effects in the treatment of PCOS, traditional Chinese medicine therapy (traditional Chinese medicine compound, single Chinese medicine, Chinese medicine extract) from the whole, by regulating the above mechanism, effectively improve the endocrine disorders, blood glucose, ovarian function, ovulation status and pregnancy rate of PCOS patients. By collecting literature in recent years, this paper expounded the mechanism of traditional Chinese medicine in the treatment of PCOS in many aspects, aiming to provide theoretical basis for clinical intervention of PCOS by traditional Chinese medicine.

Polycystic ovary syndrome (PCOS) with insulin resistance (IR) is a common endocrine disorder that is particularly prevalent in obese patients. With the continuous acceleration of the pace of life, the increasingly diversified lifestyle and the continuous change of living environment, the disease has become one of the important reproductive endocrine diseases affecting the physical and mental health of women at home and abroad. Western medicine mainly treats PCOS with life intervention, hypoglycemic drugs and contraceptives, but the side effects of drugs are relatively large, and the recurrence rate is high after stopping the drug. The treatment principles of traditional medicine for obese PCOS-IR mainly follow the holistic concept and the idea of syndrome differentiation and treatment, aiming at regulating endocrine function and improving metabolic status, so as to achieve the effect of treating both symptoms and root causes, with significant therapeutic effect, small side effects and low overall cost. Based on the medical thoughts of Fu Qing, the feasibility of treating obese PCOS-IR with Fu's Modified Flavor Buzhong Yiqi Decoction was discussed in combination with the records of ancient books and the thoughts of various doctors, so as to provide a new idea for the clinical treatment of obese PCOS-IR patients.

Objective: To explore the application effect of family-integrated care (FICare) in senile weakened patients with severe pneumonia. Method: A total of 113 senile weakened patients with severe pneumonia were selected from the 900th Hospital of Joint Logistics Support Force, PLA from June 2022 to June 2023. They were randomly divided into control group (n=55) and observation group (n=58). The control group was treated with routine nursing, and the observation group was treated with FICare based on the control group. Lung function, self-efficacy, quality of life before and at 3 months of nursing and family satisfaction were compared between the two groups. Result: At 3 months of nursing, the forced lung capacity (FVC), the percentage of forced expiratory volume in the first second to the expected value (FEV1%pred) and peak respiratory flow rate (PEF) of the two groups were increased, and the FVC, FEV1%pred and PEF of the observation group were higher than those of the control group, the differences were statistically significant (P<0.05). At 3 months of nursing, the general self-efficacy scale (GSES) score of both groups increased, and the GSES score of the observation group was higher than that of the control group, the difference was statistically significant (P<0.05). At 3 months of nursing, the physiological, psychological, environmental and social scores of the two groups were increased, and the physiological, psychological, environmental and social scores in the observation group were higher than those of the control group, the differences were statistically significant (P<0.05). The total satisfaction of family members in the observation group was higher than that in the control group, and the difference was statistically significant (P<0.05). Conclusion: FICare can effectively improve lung function, self-efficacy and quality of life in senile weakened patients with severe pneumonia, and the nursing satisfaction of family members is higher.

In this paper, the demand status, composition and key points, clinical research status, advantages and disadvantages of maternal and infant continuous nursing based on Internet+multidisciplinary collaboration model are reviewed, and its application progress in maternal and infant continuous nursing is analyzed, it is found that the nursing model is conducive to improving the quality of maternal care and improving the efficiency of maternal and infant nursing services, so as to promote maternal and infant health, it is a nursing method worthy of clinical promotion. It is believed that through further clinical practice and exploration, the multidisciplinary collaborative model of maternal and infant continuous nursing based on Internet+will be more in line with clinical needs and help to improve the overall maternal and infant nursing level in China.

Objective: To explore the application effect of fine intervention in wound nursing of severe diabetes foot. Method: A total of 80 patients with severe diabetes foot who admitted to the First Affiliated Hospital of Xiamen University from January 2023 to January 2024 were selected as the research objects, they were divided into the control group and the observation group according to the principle of randomization, with 40 cases in each group. The control group was given routine nursing during hospitalization, and the observation group was given fine intervention during hospitalization. The clinical indexes, blood glucose indexes, quality of life and nursing satisfaction were compared between two groups. Result: The wound healing time of the observation group was earlier than that of the control group, the visual analogue scale (VAS) score was lower than that of the control group, and the nursing satisfaction was higher than that of the control group, the differences were statistically significant (P<0.05); after intervention, the fasting blood glucose, 2 h postprandial blood glucose and glycosylated hemoglobin in two groups were decreased, and those in the observation group were lower than the control group, the differences were statistically significant (P<0.05); after intervention, the scores of physiological function, psychological function, role and physical function in two groups were increased, and those in the observation group were higher than the control group, the differences were statistically significant (P<0.05). Conclusion: Fine intervention can promote the severe diabetes foot patients' wound healing, relieve pain, reduce blood glucose levels, and improve quality of life and nursing satisfaction.

Chronic kidney disease is a major disease that endangers human health because of its high prevalence rate, poor awareness rate and high treatment cost. Renal anemia is a common complication of chronic kidney disease, and chronic kidney disease can also cause many cardiopulmonary complications, which has a serious impact on the quality of life and prognosis of patients with chronic kidney disease. The article reviews the effects of chronic kidney disease and renal anemia on cardiopulmonary function, focusing on the cardiovascular disease (CVD)and pulmonary diseases caused by them, such as chronic kidney disease caused by heart failure, ischemic cardiomyopathy, obstructive sleep apnea hypopnea syndrome, pulmonary hypertension and other diseases, renal anemia caused by heart failure, coronary heart disease and other diseases were analyzed, and the possible mechanism of action was discussed. At the same time, integrated analysis of the current research status and research gaps, found that the effects of renal anemia on cardiopulmonary function and the specific mechanism of related studies are still few, pointing out the direction of future research.

Objective: To comprehensively analyze the clinical efficacy of using Chifeng Yingyuan acupuncture at Huiyang point in the treatment of female stress urinary incontinence (SUI). Method: 106 female SUI patients admitted to Shenzhen Integrated Traditional Chinese and Western Medicine Hospital from July 2022 to January 2024 were selected as the study objects and randomly divided into a control group (42 cases, electroacupuncture at Huiyang point+pelvic floor muscle training) and an observation group (64 cases, pelvic floor muscle training+red phoenix Yingyuan needle puncture at Huiyang point) using a random number table method. The corresponding datas of the Visual Analog Scale (VAS) scores and the International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF) questionnaire scores before treatment, after 4 weeks of treatment, and at 4 weeks, 8 weeks, and 12 weeks of follow-up were compared. And the efficacy of the 1-hour urine cushion test between the two groups also were compared. Result: Before treatment, there was no statistically significant difference in the comparison of VAS and ICIQ-SF between the two groups (P>0.05). After 4 weeks of treatment and follow-up at 4 weeks, 8 weeks, and 12 weeks, the VAS and ICIQ-SF in the observation group were lower than those in the control group, and the difference was statistically significant (P<0.05). The total effective rate of the 1-hour urine cushion test in the observation group was higher than that of control group, and the difference was statistically significant (P<0.05). Conclusion: The use of Chifeng Yingyuan acupuncture at Huiyang point in the treatment of female SUI has a positive effect, which can effectively improve the patient's urinary incontinence symptoms and thus enhance overall efficacy.

Objective: To observe the application effect of Qili Qiangxin capsules and dopamine and furosemide pump infusion in patients with acute exacerbation of chronic heart failure. Method: According to the random envelope method, 86 patients with acute onset of chronic heart failure admitted to the First People's Hospital of Kashgar Region from February 2022 to December 2023 were divided into control group (39 cases) and study group (47 cases). Both groups received conventional treatment. The control group was treated with intravenous injection of dopamine and furosemide, while the study group was treated with Qili Qiangxin capsule. Cardiac function, vascular endothelial function, improvement of clinical symptoms, adverse reactions and clinical efficacy were compared between the two groups. Result: The total effective rate, mean arterial pressure, 6-minute walking test (6MWT), left ventricular ejection fraction (LVEF), cardiac output (CO) and nitric oxide (NO) levels in the study group were higher than those in the control group. Left ventricular end-systolic diameter (LVESD), left ventricular end-diastolic diameter (LVEDD), resting heart rate, brain natriuretic peptide (BNP), endothelin-1 (ET-1) levels of study group were lower than those of control group, and the differences were statistically significant (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion: Based on the conventional treatment of acute chronic heart failure, Qili Qiangxin capsule combined with dopamine and furosemide pump infusion can effectively alleviate the symptoms of heart failure in patients, improve vascular endothelial function, inhibit ventricular remodeling, restore blood circulation in the venous system, and further improve the heart function of patients, with high safety and practicability.

Coronary artery disease (CAD) is a common disease that endangers human health. Due to the rapid development of China's economy, people's living standards have also improved from food and clothing to a well-off level, the proportion of high-calorie diets such as cholesterol in the dietary structure has increased, and the psychological pressure of life and work has increased, so that the incidence of coronary heart disease is also increasing. As an important pathological basis of cardiovascular diseases, more and more doctors and scholars have paid attention to atherosclerosis (AS) and conducted a lot of research on its prevention and treatment. The pathogenesis of AS mainly includes inflammatory response, oxidative stress, vascular endothelial damage, lipid metabolism disorders, etc., and for the pathogenesis of AS, traditional Chinese medicine mainly relies on the effects of antioxidant stress, anti-inflammatory response, improvement of lipid metabolism, and adjustment of vascular endothelium. A large number of studies have shown that traditional Chinese medicine (TCM) has a significant advantage in the prevention and treatment of coronary atherosclerosis, with multiple pathways, multiple targets and few toxic side effects. The article summarizes the literature and research in the past five years to further explore the pathogenesis of coronary atherosclerosis and the role of traditional Chinese medicine in its prevention and treatment, so as to provide new ideas and directions for the prevention and treatment of coronary atherosclerotic heart disease.

Objective: To explore the clinical effect of acupuncture embedding at pressing points and whole knee three-step and nine methods for knee osteoarthritis (KOA) patients with liver and kidney deficiency. Method: A total of 80 KOA patients with liver and kidney deficiency syndrome who were admitted to Xifeng County Traditional Chinese Medicine Hospital from January 2023 to January 2024 were selected as the study objects and randomly divided into the study group and the control group, with 40 cases in each group. The study group was treated with acupoint acupuncture combined with whole knee three-step and nine methods, while the control group was treated with conventional western medicine. The clinical efficacy, knee joint function, pain level, quality of life, inflammatory factors in both groups were compared. Result: The total effective rate of the study group was higher than that of the control group, and the difference was statistically significant (P<0.05). After treatment, the University of Western Ontario and McMaster University Osteoarthritis Index (WOMAC) scores decreased in both groups, and the study group was lower than the control group, and the difference was statistically significant (P<0.05). After treatment, the scores of visual analogue scale (VAS) and knee osteoarthritis Quality of Life Scale (QOL-KOA) decreased in both groups, and the study group was lower than the control group, and the difference was statistically significant (P<0.05). After treatment, the levels of interleukin-1β (IL-1β) and interleukin-6 (IL-6) in the two groups were decreased, and the levels in the study group were lower than those in the control group, and the difference was statistically significant (P<0.05). Conclusion: In patients with KOA with hepatorenal insufficiency, the combination of acupoint acupuncture and whole knee three-step and nine methods can improve clinical efficacy, better reduce pain, improve knee joint function, and enhance quality of life. The mechanism of action is related to the regulation of IL-1β and IL-6 levels.

Objective: To explore the clinical effect and safety of Guizhi Fuling Pills in the treatment of uterine fibroids. Method: A total of 80 patients with uterine fibroids who admitted to Quanzhou Quangang District Hospital from February 2022 to August 2023 were selected as the study objects, the patients were divided into the control group and the observation group by random number table method, 40 cases in each group. The control group was treated with Mifepristone, and the observation group was treated with Guizhi Fuling Pills on the basis of the control group. The sex hormone levels, blood viscosity, uterine fibroids volume and adverse reactions were compared between two groups. Result: After treatment, the levels of follicle stimulating hormone, estradiol, progesterone, whole blood viscosity and plasma viscosity in two groups were lower than those before treatment, and those in the observation group were lower than the control group, the differences were statistically significant (P<0.05); after treatment, the uterine fibroids volume in two groups were smaller than those before treatment, and that in the observation group was smaller than that in the control group, the differences were statistically significant (P<0.05); there was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion: Guizhi Fuling Pills in the treatment of uterine fibroids can effectively improve the level of sex hormones and blood viscosity, reduce the uterine fibroids volume, and has high safety.

Objective: To analyze the clinical effect of Lianhua Qingwen Capsules combined with Oseltamivir in the treatment of patients with influenza. Method: A total of 84 patients with influenza who admitted to the 63750 Team Hospital of the Chinese People's Liberation Army from March 2023 to March 2024 were selected as the research objects, the patients were divided into the control group (n=42) and the observation group (n=42) by random number table method. The control group was treated with Oseltamivir Phosphate, the observation group was treated with Oseltamivir Phosphate combined with Lianhua Qingwen Capsules, two groups were treated for 5 d. The improvement of clinical symptoms, traditional Chinese medicine symptom score, C-reactive protein (CRP), clinical efficacy and adverse reactions were compared between two groups. Result: The disappearance times of fever, sore throat, cough and muscle acid in the observation group were shorter than those in the control group, and the differences were statistically significant (P<0.05); the main symptoms, secondary symptoms, total scores and CRP levels in the observation group after treatment were lower than those in the control group, and the differences were statistically significant (P<0.05); the total effective rate of the observation group was higher than that of the control group, and the difference was statistically significant (P<0.05); the total incidence of adverse drug reactions in the observation group was lower than that in the control group, but there was no significant difference between two groups (P>0.05). Conclusion: Lianhua Qingwen Capsules combined with Oseltamivir in the treatment of influenza can effectively accelerate the improvement of clinical symptoms, improve the inflammation control effect and treatment effect, and will not increase the adverse drug reactions, with good effectiveness and safety.

Objective: To analyze the clinical diagnostic efficacy of EB virus NA1-IgA combined with VCA-IgA detection on patients with nasopharyngeal carcinoma. Method: Blood samples of 783 patients undergoing nasopharyngeal carcinoma two items (EB virus NA1-IgA and VCA-IgA) routine were retrospectively analyzed from January 1, 2021 to July 26, 2023 in the inpatient and outpatient of Hechi People's Hospital. All samples were detected by EB virus NA1-IgA and VCA-IgA. The detection rate of nasopharyngeal carcinoma in NA1-IgA and VCA-IgA and its combined positive was compared. The diagnosis condition of nasopharyngeal carcinoma by NA1-IgA and VCA-IgA combination was analyzed. Result: Among the 783 patients, 155 cases (19.80%) were NA1-IgA positive, 114 cases (14.56%) were VCA-IgA positive, and 85 cases (10.86%) were both NA1-IgA and VCA-IgA positive. The detection rate of nasopharyngeal carcinoma in NA1-IgA and VCA-IgA positive patients was significantly higher than that in NA1-IgA and VCA-IgA alone positive patients, and the differences were statistically significant (P<0.05). The sensitivity, specificity and accuracy of NA1-IgA combined with VCA-IgA in diagnosis of nasopharyngeal carcinoma were 98.67% (74/75), 90.00% (9/10) and 97.65% (83/85) respectively. Conclusion: The combined detection of EB virus NA1-IgA and VCA-IgA has high clinical diagnostic efficacy in patients with nasopharyngeal carcinoma.

The main clinical manifestation of the third lumbar transverse process syndrome (TLTPS) is chronic pain caused by acute or chronic injury, especially the tenderness at the third lumbar transverse process, in this paper, we collected and summarized the relevant literatures about the treatment and the analysis of the curative effect of the TLTPS in recent 3 years, so as to provide more effective treatment for the clinician.

This article reviews the application and possible mechanisms of traditional Chinese medicine sensitization acupoint therapy in the treatment of depression syndrome. Based on the guidance of meridian theory, sensitize acupoints to adjust the circulation of qi and blood and the function of organs, in order to alleviate the symptoms of depression syndrome. By restoring the balance of the body, sensitization acupoint therapy can reduce symptoms, improve mental state, and be combined with medication, psychotherapy, and other treatments to enhance therapeutic effects. The mechanism of sensitization acupoint therapy for depression syndrome may involve multiple aspects, including neurobiology, immune regulation, inflammatory response, psychological and psychosomatic regulation, etc. In addition, the selection and application of sensitization acupoint therapy are guided by the theory of meridians, which restores the body's balance by adjusting the circulation of meridians. In summary, this article aims to gain a deeper understanding of the application and mechanism of sensitization acupoint therapy for depression syndrome, provide scientific basis for clinical treatment, and improve treatment effectiveness.

Objective: To explore the impact of adenoidectomy on nasal inflammation control and Th1/Th2 cell balance in children with adenoid hypertrophy and allergic rhinitis (AR). Method: 100 children with adenoid hypertrophy combined with allergic rhinitis who were treated at Puning People's Hospital from June 2022 to June 2024 were selected and randomly divided into a control group (treated with drugs, n=50) and an observation group (treated with drugs plus adenoidectomy, n=50) according to the random number table method. The control of rhinitis in the two groups, the levels of inflammatory factors [tumor necrosis factor-α (TNF-α), leukocyte mediators (IL)-4, IL-6, interferon-γ(INF-γ)] before and after treatment, and the occurrence of adverse reactions were compared. Result: The total effective rate of treatment in the observation group was higher than that in the control group, and the difference was statistically significant (P<0.05). After treatment in both groups, the levels of TNF-α, IL-4 and IL-6 decreased, and those in the observation group were lower than those in the control group. The level of INF-γ increased in both groups, and that in the observation group was higher than that in the control group. The differences were statistically significant (P<0.05). The occurrence of adverse reactions in the observation group was higher than that in the control group, but the difference was not statistically significant (P>0.05). Conclusion: Adenoidectomy can effectively increase the total effective rate of treatment for children with adenoid hypertrophy accompanied by AR, reduce the levels of inflammatory factors, and subsequently regulate the Th1/Th2 cell balance, with high safety.

Objective: To analyze the effect of five elements music therapy combined with time acupoint application on essential hypertension patients with liver-Yang hyperactivity syndrome. Method: A total of 80 patients with essential hypertension with liver-Yang hyperactivity syndrome treated in Qidong Hospital of Traditional Chinese Medicine from March 2023 to March 2024 were selected. They were divided into control group and observation group according to random number table method, with 40 cases in each group. The control group received conventional treatment, and the observation group received five elements music therapy combined with time acupoint application on the basis of the control group. Blood pressure, Chinese medicine symptom score, psychological symptoms and quality of life before and after treatment were compared. Result: After treatment, diastolic blood pressure (DBP) and systolic blood pressure (SBP) in both groups were decreased, and SBP and DBP in observation group were lower than those in control group, the differences were statistically significant (P<0.05). After treatment, the scores of vertigo and headache, facial hot, impatience and irritability, tinnitus and insomnia in both groups were reduced, and the scores of vertigo and headache, facial hot, impatience and irritability, tinnitus and insomnia in the observation group were lower than those in the control group, the differences were statistically significant (P<0.05). After treatment, the Hamilton anxiety scale (HAMA), Hamilton depression scale (HAMD) score of the two groups was decreased, and the HAMA and HAHD score of the observation group was lower than that of the control group, the differences were statistically significant (P<0.05). After treatment, mental health, social function, emotional function, physical function, vitality, physical pain, physiological function and overall health scores of both groups were increased, and mental health, social function, emotional function, physical function, vitality, physical pain, physiological function and overall health scores of the observation group were higher than those of the control group, the differences were statistically significant (P<0.05). Conclusion: Five elements music therapy combined with time acupoint application can effectively reduce the blood pressure of essential hypertension of liver-Yang hyperactivity syndrome and improve the quality of life.

Objective: To investigate the effect of Weichun capsule combined with quadruple therapy on Helicobacter pylori (Hp)-positive chronic atrophic gastritis. Method: A total of 120 patients with Hp-positive chronic atrophic gastritis admitted to Chun 'an County Traditional Chinese Medicine Hospital from October 2022 to December 2023 were selected as the study objects and randomly divided into control group and observation group, with 60 cases in each group. The control group was treated with quadruple therapy, while the observation group was treated with Weifuchun capsule combined with quadruple therapy. The clinical effect, the degree of clinical symptoms, laboratory test indexes and the results of Hp negative conversion were compared between the two groups. Result: The total effective rate, Hp negative conversion rate and the levels of pepsinogen Ⅰ (PG-Ⅰ), PG-Ⅰ / PG-Ⅱ and G17 in the observation group were higher than those in the control group, while the scores of TCM symptoms and PG-Ⅱlevels in the observation group were lower than those in the control group, with statistical significance (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion: Weifuchun capsule combined with quadruple therapy is effective in the treatment of Hp-positive chronic atrophic gastritis, which can not only increase the negative conversion rate of Hp, but also improve clinical symptoms and serum pepsinogen and G17 levels more effectively.

Objective: To study and analyze the minimally invasive advantages of intussusception transparent dilation channel in the protection of neurological function and improvement of prognosis in hypertensive intracerebral hemorrhage. Method: 90 patients with hypertensive cerebral hemorrhage admitted to Sihong Hospital from August 2021 to July 2023 were selected as the study objects, and were divided into control group and study group according to different treatment plans, with 45 cases in each group. The control group underwent traditional craniotomy, while the study group underwent intussusception transparent dilatation. Surgical indicators, cerebral blood flow parameters, serum inflammatory factors, neurological function indicators and Glasgow prognostic score (GOS) were compared between the two groups. Result: After treatment, the operation time and intraoperative blood loss in the study group were significantly lower than those in the control group, and the difference was statistically significant (P<0.05). After treatment, the hematoma clearance rate of the study group was significantly higher than that of the control group, and the difference was statistically significant (P<0.05). After treatment, the average blood flow and average blood flow velocity in the study group were significantly higher than those in the control group, with statistical significance (P<0.05). After treatment, the peripheral resistance of the study group was significantly lower than that of the control group, the difference was statistically significant (P<0.05). After treatment, the levels of serum inflammatory factors [interleukin-6 (IL-6), tumor necrosis factor-α(TNF-α) and hypersensitive C-reactive protein (hs-CRP)] in the study group were lower than those in the control group, and the difference was statistically significant (P<0.05). After treatment, the levels of neuron-specific enolase (NSE), neuropeptide Y (NPY) and brain-derived neurotrophic factor (BDNF) in the study group were significantly lower than those in the control group, and the difference was statistically significant (P<0.05). Six months after surgery, GOS prognostic score in the study group was significantly higher than that in the control group, with statistical significance (P<0.05). Conclusion: The treatment of hypertensive intracerebral hemorrhage by intusception hyaline dilation can effectively shorten the operation time, reduce the amount of intraoperative blood loss, regulate inflammatory factors, protect nerve function and improve prognosis. In this way, it can provide patients with more effective and suitable treatment and surgical options in clinical practice, and improve the survival rate and postoperative quality of life of patients.

Objective: To explore the impact of personalized nursing based on Caprini risk assessment on the incidence of deep venous thrombosis (DVT) in elderly patients with lower limb fractures. Method: A total of 80 elderly patients with lower limb fractures in Quanzhou Orthopedic-Traumatological Hospital from February to December 2023 were selected as the study subjects. The patients were divided into control group (n=40) and observation group (n=40) by random number table method. The control group received routine nursing intervention, while the observation group received personalized nursing based on Caprini risk assessment on the basis of routine nursing intervention. The differences in thigh circumference, incidence of DVT, and satisfaction between two groups of lower limbs were compared between the two groups. Result: Before surgery, there were no significant difference in thigh circumference between the two groups of lower limbs (P>0.05). At 3 d after surgery, 7 d after surgery and before discharge, the thigh circumference in the observation group were better than those in the control group , the differences were statistically significant (P<0.05). There were 1 case of DVT occurred in the observation group, with an incidence rate of 2.50%; there were 6 cases of DVT in the control group, with an incidence rate of 15.00%, and there was no statistically significant in the incidence of DVT between the two groups (P<0.05). The total satisfaction of the observation group was higher than that of the control group, the difference was statistically significant (P<0.05). Conclusion: Personalized nursing based on Caprini risk assessment can reduce the risk of DVT in elderly patients with lower limb fractures and improve patient satisfaction.

Sepsis associated acute kidney injury (SA-AKI) is characterized by significantly high morbidity and mortality, and it is urgent to further explore effective strategies to promote the progress of research and practice in this field. At present, the clinical understanding of the diagnosis and treatment of SA-AKI is still insufficient, which makes most patients have developed acute kidney injury (AKI) at the time of treatment, leading to poor prognosis. Therefore, early identification of SA-AKI is particularly important for implementing targeted treatment and improving patient outcomes. This article will focus on the pathophysiological mechanism, early novel biomarkers and corresponding treatment of SA-AKI, hoping to provide a useful reference for clinical research.

Objective: To investigate the effect of oral four vitamins combined with Iodine Glycerin in the treatment of oral ulcer. Method: A total of 94 patients with oral ulcer who admitted to Qianxinan Autonomous Prefecture Hospital of Traditional Chinese Medicine from June 2022 to June 2023 were selected as the research objects, they were divided into the control group and the observation group by random number table method, with 47 cases in each group. The control group was treated with Iodine Glycerin, and the observation group was treated with four vitamins on the basis of the control group, the efficacy, epidermal growth factor, immune indexes and inflammatory factors were compared between two groups. Result: The total effective rate of the observation group was higher than that of the control group, and the difference was statistically significant (P<0.05); after 30 d of treatment, the epidermal growth factor, CD3+, CD4+ and CD4+/CD8+ in two groups were higher than those before treatment, and those in the observation group were higher than those in the control group, the differences were statistically significant (P<0.05); after 30 d of treatment, the levels of interleukin-1 (IL-1), interleukin-8 (IL-8), interleukin-17 (IL-17) and tumor necrosis factor-α (TNF-α) in two groups were lower than those before treatment, and those in the observation group were lower than those in the control group, the differences were statistically significant (P<0.05). Conclusion: Oral four vitamins combined with Iodine Glycerin is effective in the treatment of oral ulcer, which can increase epidermal growth factor, improve immune function and reduce inflammatory response.

Objective: To investigate the clinical effect of combined administration of voronolazone and esomeprazole in patients with refractory gastroesophageal reflux (GERD) positive helicobacter pylori (Hp). Method: A total of 80 patients with Hp-positive refractory GERD treated in Dongtai People's Hospital from January 2021 to October 2023 were selected as the study objects, and grouped according to treatment differences, with 40 cases in each group. Patients in both groups received basic intervention. The control group was treated with esomeprazole, while the study group was treated with Vonolazine fumarate tables on the basis of control group. The levels of gastrointestinal hormones, inflammatory factors, adverse reactions and clinical efficacy of the two groups were compared. Result: Before treatment, there was no significant difference in gastrointestinal hormone levels between the two groups (P>0.05). After treatment, VIP in the study group was lower than that before treatment, and lower than that in control group, with statistically significance (P>0.05). After treatment, gastrin and motilin in study group were higher than that before treatment, with statistical significance (P<0.05). Before treatment, there was no significant difference in the levels of inflammatory factors between the two groups (P>0.05). After treatment, CRP, C-creative protein, interleukin-6 and TNF-α in the study group were lower than those before treatment and lower than those in control group, and the difference was statistically significant (P<0.05). After treatment, the incidence of abdominal pain, diarrhea, nausea and vomiting in the study group was lower than that in the control group, and the difference was statistically significant (P<0.05). After treatment, the total effective rate of the study group was higher than that of the control group, and the difference was statistically significant (P<0.05). Conclusion: Venolazan combined with esomeprazole can improve the level of gastrointestinal hormones and inflammatory factors in patients with Hp-positive refractory gastroesophageal reflux disease, thus improving the clinical effect of patients with high safety.

Objective: To explore the clinical effect of Montmorillonite Powder combined with Bifidobacterium Tetravalent Live Bacteria in the treatment of acute gastroenteritis (AGE). Method: A total of 60 patients with AGE who admitted to the Department of Emergency Medicine of Jiangyin People's Hospital from March 2023 to May 2024 were selected as the research objects, they were divided into the control group and the study group according to the random number table method, with 30 cases in each group. Two groups were given symptomatic treatment such as bed rest, rehydration, correction of electrolyte, etc, the control group was given oral Montmorillonite Powder, and the study group was given oral Bifidobacterium Tetravalent Live Bacteria Tablets on the basis of the control group, two groups were treated for 3 d. The remission times of clinical symptoms (diarrhea, abdominal pain, nausea and vomiting), curative effect, stool frequency, stool trait score, immune function (CD4+, CD8+ and CD4+/CD8+) were compared between two groups. Result: The remission times of diarrhea, abdominal pain, nausea and vomiting in the study group were earlier than those in the control group, the total effective rate was higher than that in the control group, the differences were statistically significant (P<0.05); the stool frequency in the study group after treatment was less than that in the control group, the stool trait score was lower than that in the control group, and CD4+ and CD4+/CD8+ were higher than those in the control group, the differences were statistically significant (P<0.05). Conclusion: Montmorillonite Powder combined with Bifidobacterium Tetravalent Live Bacteria can shorten clinical symptoms relief time, improve therapeutic effects, reduce stool frequency and stool trait scores, and improve immune function in AGE patients.

[Abstract].Objective: To explore the clinical efficacy of Amlodipine Folic Acid Tablets in the treatment of H-type hypertension and pharmacoeconomics evaluation. Method: A total of 141 patients with H-type hypertension admitted to the First Hospital of Sanming Affiliated to Fujian Medical University from August 2022 to August 2023 were retrospectively selected as the study objects. According to the use of drugs, they were divided into group A, group B and group C, 47 cases in each group. Group A was given Amlodipine Besylate Tablets, group B was given Amlodipine Folic Acid Tablets, group C was given Enalapril Maleate Folic Acid Tablets. The clinical efficacy, blood pressure index, homocysteine (Hcy), vascular endothelial function and inflammatory factors before and after treatment, adverse reactions and pharmacoeconomics were compared between the two groups. Result: The total effective rate of group B was significantly higher than that of group A and group C, and the difference was statistically significant (P<0.05). After treatment, systolic blood pressure (SBP), diastolic blood pressure (DBP) and Hcy levels were all reduced in the three groups, and SBP, DBP and Hcy levels in group B were lower than those in group A and group C, the indexes in the group C were lower than those in the group A, the differences were statistically significant (P<0.05). After treatment, nitric oxide (NO) in the three groups were increased, endothelin-1 (ET-1), tumor necrosis factor-α (TNF-α), interleukin-6 (interleukin-6), and hypersensitive C-reactive protein (hs-CRP) were decreased, and the level of NO in group B was significantly higher than that in group A and group C, while the levels of ET-1, TNF-α, IL-6 and hs-CRP were significantly lower than those in group A and group C, the levels of NO in group C was significantly higher than that in group A, and the levels of ET-1, TNF-α, IL-6 and hs-CRP were significantly lower than those in group A, the differences were statistically significant (P<0.05). There was no significant difference in the incidence of adverse reactions among the three groups (P>0.05). The drug cost of group B was lower than that of group A and group C, group C was lower than group A, and the differences were statistically significant (P<0.05). Conclusion: Amlodipine Folic Acid Tablets has good clinical effect in the treatment of H-type hypertension, which not only effectively reduces blood pressure, Hcy level and inflammatory factor level, but also improves vascular endothelial function, which is more economical.

Objective: To observe the effect of Jianpi Shengxue Granules combined with Ferrous Succinate in the treatment of patients with iron deficiency anemia during pregnancy. Method: A total of 128 patients with iron deficiency anemia during pregnancy treated in Jintai Hospital in Baoji City from January to December 2023 were selected. They were divided into control group (n=64) and observation group (n=64) according to random number table method. The control group was treated with Ferrous Succinate, and the observation group was treated with Jianpi Shengxue Granules on the basis of the control group. The clinical efficacy, blood biochemical and iron metabolism indexes before and after medication, pregnancy outcome and adverse reactions were compared between the two groups. Result: The total effective rate of the observation group was higher than that of the control group, and the difference was statistically significant (P<0.05). After treatment, red blood cell count (RBC), mean red blood cell hemoglobin concentration (MCHC), hematocrit (HCT) and hemoglobin (Hb) levels in both groups were increased, and RBC, MCHC, HCT and Hb levels in observation group were higher than those in control group, the differences were statistically significant (P<0.05). After treatment, the levels of ferritin (SF), transferrin (TRF), iron concentration (SI) and iron regulating hormone (HEPC) in both groups were increased, and the levels of SF, TRF, SI and HEPC in observation group were higher than those in control group, the differences were statistically significant (P<0.05). The incidences of preterm birth, cesarean section, puerperal infection, postpartum hemorrhage, low birth weight infants and neonatal asphyxia in observation group were lower than those in control group, and the differences were statistically significant (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion: The application of Ferrous Succinate combined with Jianpi Shengxue Granules in the treatment of iron-deficiency anemia in pregnancy can effectively regulate iron metabolism, improve blood biochemical indexes, reduce adverse pregnancy outcomes, with definite clinical effect and drug safety.

Nervous tinnitus, as one of the most common clinical tinnitus symptoms, causes serious damage to the patient's physical and mental health and quality of life. At present, there is a lack of effective therapeutic drugs for nervous tinnitus in clinical practice, acupuncture have good effects and safety in the treatment of nervous tinnitus, and the methods of acupuncture in the treatment of nervous tinnitus are becoming more and more abundant, under the guidance of traditional Chinese medicine theory, it can effectively reduce the severity of symptoms, ensure the therapeutic effect, and play a positive role in improving physical and mental health. This article is a brief summary of the etiology and pathogenesis of nervous tinnitus and the methods of acupuncture treatment of nervous tinnitus, hoping to provide an effective reference for the treatment of neural tinnitus.

Objective: The purpose of this study is to investigate the clinical effectiveness of Xiangsha Liujunzi Decoction combined with moxibustion in the treatment of chronic atrophic gastritis, providing new insights and reference for the treatment of this disease. Method: 126 patients with chronic atrophic gastritis admitted to Beijing Huairou District Hospital of Traditional Chinese Medicine from September 2022 to September 2023 were randomly divided into control group and observation group, with 63 patients in each group. The control group was treated with conventional western medicine combined with Xiangsha Liujunzi decoction, and the observation group was treated with moxibustion on this basis. Clinical efficacy, levels of inflammatory factors and Gastrin (GAS), gastroscopy and pathological improvement, and Short Form 36-item Health Survey (SF-36 score) were compared between the two groups before and after treatment to evaluate the effects of different treatments. Result: There were no significant differences in age, gender, course of disease and other baseline data between the two groups (P>0.05). The effective and the total effective rate of the observation group, significantly higher than those of the control group (P<0.05). After treatment, compared with the control group, the CRP level and IL-6 level in the observation group were significantly decreased, and the GAS level was significantly increased. The reduction range in the observation group was greater than that in the control group, and the difference was statistically significant (P<0.05). After six months of follow-up, gastroscopy and pathological improvement showed that the observation group was better than the control group in terms of inflammation remission, atrophy improvement and intestinal metaplasia reversal, and the difference was statistically significant (P<0.05). The SF-36 score of quality of life showed that the improvement of physical function, role function, emotional health and vitality in the observation group was better than that in the control group, and the difference was statistically significant (P<0.05). Conclusion: The combination of Xiangsha Liujunzi Decoction and moxibustion in the treatment of chronic atrophic gastritis can significantly improve clinical effectiveness, reduce levels of inflammatory factors, promote the recovery of gastric pathological conditions, and enhance patients' quality of life. This combined therapy is an effective method for treating chronic atrophic gastritis.

Objective: To observe and explore the clinical effect of betahistine hydrochloride combined with ginkgo biloba extract on patients with vascular vertigo. Method: A total of 106 patients with vasogenic vertigo admitted to the Luochuan County Hospital from February 2022 to March 2024 were selected as the study subjects, and were divided into control group (treated with betahistine hydrochloride, 53 cases) and observation group (treated with betahistine hydrochloride plus ginkgo biloba extract, 53 cases) according to random number method. The total effective rate, cerebral arterial blood flow, plasma fibrinogen (FIB), erythrocyte sedimentation rate (ESR), vascular endothelial growth factor (VEGF), C-reactive protein (CRP), serum amylase and adverse reactions were compared between the two groups. Result: The total effective rate of the observation group was higher than that of the control group (P<0.05). Before treatment, there was no difference in the comparison of cerebral artery blood flow, FIB, ESR, VEGF, CRP, and serum amylase levels between the two groups (P>0.05). After treatment, the cerebral artery blood flow and VEGF of the patients in the two groups increased, and the levels of FIB, ESR, CRP and serum amylase decreased. The cerebral artery blood flow and VEGF of the patients in the test group were higher than those in the control group, and the levels of FIB, ESR, CRP, and the serum amylase in the test group were lower than those in the control group (P<0.05). There was no difference in the comparison of adverse reactions between the two group (P>0.05). Conclusion: Betahistine hydrochloride combined with ginkgo biloba extract can further increase cerebral artery blood flow, improve the levels of FIB, ESR and VEGF, and reduce inflammatory reaction in patients with vascular vertigo. It has definite clinical efficacy and is safe to use.

Objective: To observe the clinical effect of Modified Zuojin Pills combined with Omeprazole in the treatment of reflux pharyngitis, and to provide a favorable reference for future clinical treatment. Method: Eighty-six patients with reflux pharyngitis admitted to Capital Medical University Affiliated Beijing Tongren Hospital Mentougou Hospital from March 2019 to May 2023 were selected and divided into two groups by random number table method. The control group (n=43) was treated with Omeprazole, and the observation group (n=43) was treated with Modified Zuojin Pills on the basis of Omeprazole. The therapeutic effect, laryngeal mucous pepsin concentration, reflux symptom index scale (RSI) score, reflux finding scale (RFS) score, symptom score, signs score and gastrointestinal hormone index before and after treatment of the two groups were compared, and adverse reactions during medication was recorded. Result: The total effective rate was 93.02% (40/43) in the observation group, which was higher than 69.77% (30/43) in the control group, the difference was statistically significant (P<0.05). The laryngeal mucus pepsin concentration, RSI scores, RFS scores, symptom scores, sign scores, pepsinogen Ⅰ (PGⅠ) and gastrin stimulating hormone (GAS) levels in the two groups after treatment were all lower than those before treatment, and the indexes in the observation group were lower than those in the control group, motilin (MTL) were higher than those before treatment, and the observation group was higher than the control group, the differences were statistically significant (P<0.05). The adverse reaction rate was 11.63% (5/43) in the observation group and 6.98% (3/43) in the control group, the difference was not statistically significant (P>0.05). Conclusion: Modified Zuojin Pills combined with Omeprazole can further improve the symptoms and signs of patients with reflux pharyngitis, regulate gastrointestinal hormones, improve the efficacy and safety.

Acute kidney injury (AKI) is a global problem, affecting millions of patients worldwide, and over the past few decades, many research results have improved our understanding of AKI, standardizing the diagnostic criteria for AKI and influencing subsequent clinical treatment in Kidney Diseases: Improving Global Outcomes (KDIGO) in 2012. Glutamine (GLN) is a non-essential amino acid that is abundant in healthy humans, and previous studies have shown that GLN supplementation can be used to prevent new infections in uninfected patients or subsequent infections in critically ill patients who have already been infected, and is part of the clinical nutritional supplement regimen and recommended immunosuppressive individuals. With the continuous updating of AKI treatment guidelines and the in-depth exploration of GLN metabolism, more and more researchers have found that GLN plays a non-ignorable protective role in clinical AKI and critically ill patients. This review introduces the possible protective mechanism and clinical reference of GLN metabolism in the occurrence of AKI diseases, so as to provide a reference for better treatment of AKI patients. It can effectively protect the renal function of AKI patients, alleviate the disease symptoms and improve the prognosis of the disease.

The application of external treatment of Chinese medicine in the treatment of bone fracture has a long history and is widely used, which can be used as one of the non-surgical treatments for bone fracture to provide patients with a variety of therapeutic choices, and can also be combined with surgical treatments as an important part of the preoperative preparations or postoperative rehabilitation, which has the advantages of small side effects, few contraindications and so on. Meanwhile, with the development of science and technology in recent years, there are new advances in the application of external treatment of Chinese medicine to assist in the treatment of bone fracture, which is reviewed in this paper, with a view to providing reference for the application of external treatment in future clinical work.

Hypertension, hyperglycemia, and hyperlipidemia are important components of metabolic syndrome (MS), which tend to cluster and multiply the risk of systemic multisystem diseases. Obesity, overeating and reduced activity are traditional risk factors that promote the co-morbidity of HFSS. However, recent studies have found that some potential risk factors are closely related to the occurrence of HFSS. Therefore, based on the high prevalence rate and the low prevention awareness of the public, this paper reviews the emerging potential risk factors and intervention measures for the co-morbidity of the three high diseases, in order to provide a new perspective for the early prevention and treatment of the three high diseases, and provide scientific basis and practical guidance for alleviating the occurrence of metabolic disorders and systemic diseases caused by the three high diseases.

Objective: To investigate the clinical efficacy of secuchiumab in the treatment of ankylosing spondylitis and its effect on spinal function. Method: 80 patients with ankylosing spondylitis (AS) admitted to Jinjiang City Hospital from January 2022 to January 2024 were selected as the study objects. They were divided into Adamu group and Secuchiu group according to different medication regimens, with 40 cases in each group. Adamu group received adamumab treatment, while the Secuchiumab group received secuchiumab treatment, and all patients continued to receive treatment for 3 months. The treatment effectiveness of the two groups was compared. Spinal function (ankylosing spondylitis Function Index (BASFI), Bath Ankylosing Spondylitis Metrology index (BASMI), morning stiffness duration], laboratory indicators [erythrocyte subsidence rate (ESR), C-reactive protein (CRP)] and drug safety were compared between the two groups before and after treatment. Result: The effective rate of Sikuchiyou group was higher than that of Adamu group, and the difference was statistically significant (P<0.05). After treatment, the BASFI and BASMI of Secuchiyou group were lower than those of Adamu group, the duration of morning stiffness was shorter than that of Adamu group (P<0.05). After treatment, compared with Adamu group, both ESR and CRP in Secuchiu group were lower (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion: The treatment effect of secuchiumab in patients with AS is better than that of adalimumab, which is beneficial to improve the spinal function of patients, shorten the morning rigor time, promote blood circulation, reduce inflammatory factors, and no obvious adverse reactions were observed.

Among the growth and development diseases of children in China, short stature (SS) accounts for a high proportion, with the improvement of living standards, parents pay more attention to children's height. Western medicine treatment of SS mainly uses subcutaneous injection of Recombinant Human Growth Hormone, the clinical efficacy of individual differences is obvious, the treatment time is long, and the compliance of children is poor. The treatment of SS in traditional Chinese medicine is to take the corresponding prescription orally after syndrome differentiation and treatment of traditional Chinese medicine, at the same time, it can be combined with acupuncture, massage, acupoint application and other external treatment methods of traditional Chinese medicine to achieve the therapeutic effect, the clinical observation shows that the treatment effect of traditional Chinese medicine is obvious, and it has the advantages of low treatment cost and less side effects, therefore, it is worth popularizing and further studying. This article review the literature of SS-related traditional Chinese medicine and western medicine treatment in the past five years, in order to providing new treatment ideas and methods for clinical treatment of SS.

Objective: To explore the application value of flexible ureteroscope combined with flexible flexible negative pressure ureteric sheath in the treatment of kidney stones. Method: A total of 180 patients with kidney stones admitted to the Sixth Hospital of Guiyang City from June 2022 to May 2023 were selected for this study. After numbering them according to the admission order, they were randomly divided into two groups with 90 cases each by drawing lots. In the control group, flexible ureteroscope lithotripsy (FURL) was performed with a non-flexible ureteral guide sheath. Observation group was treated with FURL, ureteral access sheath (FURS). After treatment, the surgical quality, general indexes, pain degree, complications and quality of life of the two groups were compared. Result: The stone clearance rate of the observation group was 95.56% (86/90), and that of the control group was 85.56% (77/90). The stone clearance rate of the observation group was significantly higher than that of the control group, and the difference was statistically significant (P<0.05). The indexes of intraoperative blood loss and hospital stay in the observation group were lower than those in the control group, and the difference was statistically significant (P<0.05). Before surgery, there was no significant difference in visual analogue scale (VAS) between the two groups (P>0.05). The observation group was lower than the control group 1 d and 2 d after operation, and the difference was statistically significant (P<0.05). The complication rate of urinary tract infection in the observation group was lower than that in the control group, the difference was statistically significant (P<0.05). There was no significant difference in quality of life scores between the two groups before operation (P>0.05). The score of quality of life in the observation group was higher than that in the control group, and the difference was statistically significant (P<0.05). Conclusion: The use of FURL and FURS can improve the surgical efficiency, facilitate the removal of stones, improve the surgical quality, shorten the operation time, reduce the surgical trauma, facilitate the postoperative rehabilitation of patients, reduce the pain degree of patients, and improve the life quality of patients.

Objective: To examine the treatment strategy's efficacy and safety in administering methylprednisolone sodium succinate injections beneath the mastoid periosteum in the retroauricular groove for patients with Sudden Sensorineural Hearing Loss (SSNHL). Method: From June 2022 to January 2024, 118 patients with Sudden Sensorineural Hearing Loss (SSNHL) admitted to Wujin Hospital Affiliated to Jiangsu University were selected as the study objects and randomly divided into a control group and a trial group, with 59 cases in each group. The control group was treated with sodium phosphate dexamethasone injections, while the experimental group was treated with methylprednisolone sodium succinate injections. All patients were treated by injection to the retroauricular sulci mastoid periosteum. The changes of pure tone hearing threshold and hemorheology indexes before and after treatment were analyzed in the two groups, and the clinical effective rate and the incidence of adverse reactions during treatment were evaluated. Result: After treatment, the average listening valves in pure tone region, low frequency region and high frequency region of experimental group were lower than those in control group, and the difference was statistically significant (P<0.05). After treatment, the changes of whole blood high tangential viscosity, whole blood low tangential viscosity and plasma viscosity in the study group were lower than those in the control group, and the differences were statistically significant (P<0.05). The total clinical effective rate of experimental group was higher than that of control group, and the difference was statistically significant (P<0.05). There was no significant difference in the comparison of adverse reactions between the two groups (P>0.05). Conclusion: In the treatment with SSNHL, the efficacy of methylprednisolone sodium succinate injection treatment is better than dexamethasone, which can improve patients' hearing and blood indexes and has high safety.

Objective: To investigate the application effect of Baofukang Gel in the patients with senile vaginitis. Method: A total of 100 patients with senile vaginitis admitted to the First Affiliated Hospital of Fujian Medical University from April 2023 to April 2024. According to the random number table method, they were divided into a control group and an observation group, with 50 cases in each group. The control group was given Conjugated Estrogen Cream, and the observation group was given Baofukang Gel on the basis of the control group. The clinical efficacy, adverse reactions, vaginal inflammation symptom and sign scores, pH value, cellular immune index, and vaginal secretion detection indicators before treatment, after 1 week and 2 weeks of treatment between two groups were compared. Result: The total effective rate of the observation group was significantly higher than that of the control group, and the difference was statistically significant (P<0.05). The incidence of adverse reactions in the observation group was significantly lower than that in the control group, and the difference was statistically significant (P<0.05). After 1 week and 2 weeks of treatment, the itching, burning sensation, and dryness scores in the observation group were significantly lower than those in the control group, and the difference was statistically significant (P<0.05). After 1 week and 2 weeks of treatment, the pH value of the observation group was significantly lower than that of the control group, and the difference was statistically significant (P<0.05). After 1 week and 2 weeks of treatment, the observation group showed significantly higher levels of CD3+, CD4+, and CD4+/CD8+ compared to the control group, and the difference was statistically significant (P<0.05). After 1 week and 2 weeks of treatment, the levels of 37 amino acids at the N-terminus of cathelicidin LL-37, human beta defence-2 (HBD-2), and human beta defence-3 (HBD-3) in the observation group were significantly lower than those in the control group, and the differences were statistically significant (P<0.05). Conclusion: The application of Baofukang Gel in senile vaginitis has good effect, high safety, and can significantly improve the local immune status of patients.

As one of the traditional Chinese medicine therapies, acupuncture and moxibustion can invigorate the body and expel pathogens, regulate qi and blood, and has a significant effect in treating and improving tumor related symptoms. This article mainly summarizes the treatment of cancer related fatigue, bone marrow depression, gastrointestinal adverse reactions, related insomnia, depression, peripheral neuropathy injury and other aspects of tumor, in order to explore the feasibility of acupuncture and moxibustion in the treatment of tumor related symptoms, and provide scientific basis for acupuncture and moxibustion to prevent and treat malignant tumors.