Objective: To assess the therapeutic response of tongue acupuncture in patients with post-stroke dysphagia (PSD). Method: Medical records of PSD patients consecutively admitted to Yangjiang Hospital of Traditional Chinese Medicine between October 2021 and December 2022 were retrospectively analyzed. Eighty patients meeting the inclusion criteria were enrolled. Participants were stratified into a control group (n=40) and a tongue acupuncture group (n=40) based on the specific therapeutic regimen received. The control group was given rehabilitation therapy, while the treatment group was combined with tongue acupuncture. The differences in Water Swallowing Test (WST) grades and Standardized Swallowing Assessment (SSA) scores were compared. The therapeutic outcomes and adverse events were documented following the intervention period. Result: Baseline equivalence in WST grades and SSA scores was observed, demonstrated no significant intergroup differences (P>0.05). Post-therapy, the tongue acupuncture cohort demonstrated greater WST improvement, lower SSA scores, and higher clinical efficacy rates versus controls, differences were statistically significant (P<0.05). No adverse events occurred in either group. Conclusion: Tongue acupuncture combined with rehabilitation achieves superior dysphagia mitigation in PSD compared to rehabilitation alone, with sustained short-term effects observed at 3-month follow-up and an optimal safety trajectory.

Gastroesophageal reflux disease (GERD) is a common chronic digestive disorder characterized by symptoms such as reflux, heartburn, bloating, belching, and chest pain, which can lead to severe complications like esophageal adenocarcinoma. With the ongoing social and economic development and lifestyle changes, the prevalence of GERD continues to rise, particularly in Asian countries. Although proton pump inhibitors (PPIs) are considered as the first-line treatment, monotherapy presents limitations, such as incomplete symptom relief and long-term safety concerns. Therefore, recent treatment strategies have gradually shifted towards diversification and personalization. The study summarizes the latest advances in GERD treatment, including the use of acid-suppressing agents, prokinetics, mucosal protectants, reflux inhibitors, and neuromodulators, as well as non-pharmacological interventions such as endoscopic and surgical therapies. Additionally, the treatment characteristics for special populations, including children, the elderly, and pregnant women, are discussed. By optimizing combination therapy and individualized approaches, the clinical outcomes for GERD patients and their quality of life are expected to improve further.

Objective: To explore the impact of adenoidectomy on nasal inflammation control and Th1/Th2 cell balance in children with adenoid hypertrophy and allergic rhinitis (AR). Method: 100 children with adenoid hypertrophy combined with allergic rhinitis who were treated at Puning People's Hospital from June 2022 to June 2024 were selected and randomly divided into a control group (treated with drugs, n=50) and an observation group (treated with drugs plus adenoidectomy, n=50) according to the random number table method. The control of rhinitis in the two groups, the levels of inflammatory factors [tumor necrosis factor-α (TNF-α), leukocyte mediators (IL)-4, IL-6, interferon-γ(INF-γ)] before and after treatment, and the occurrence of adverse reactions were compared. Result: The total effective rate of treatment in the observation group was higher than that in the control group, and the difference was statistically significant (P<0.05). After treatment in both groups, the levels of TNF-α, IL-4 and IL-6 decreased, and those in the observation group were lower than those in the control group. The level of INF-γ increased in both groups, and that in the observation group was higher than that in the control group. The differences were statistically significant (P<0.05). The occurrence of adverse reactions in the observation group was higher than that in the control group, but the difference was not statistically significant (P>0.05). Conclusion: Adenoidectomy can effectively increase the total effective rate of treatment for children with adenoid hypertrophy accompanied by AR, reduce the levels of inflammatory factors, and subsequently regulate the Th1/Th2 cell balance, with high safety.

Objective: To investigate the clinical effect of Montelukast sodium combined with Yupingfeng granules in the treatment of allergic rhinitis in children. Method: A cohort of 100 pediatric patients diagnosed with allergic rhinitis was enrolled from Yangjiang Maternal and Child Health Hospital from April 2023 to April 2024. Participants were randomly allocated via a random number table into two groups (n=50 each): control group receiving 0.9% saline nasal irrigation combined with montelukast sodium monotherapy, and research group receiving 0.9% saline nasal irrigation plus a combined regimen of montelukast sodium and Yupingfeng granules. Treatment efficacy and safety were evaluated by comparative analysis of Traditional Chinese Medicine (TCM) syndrome scores, inflammatory cytokine levels, and immunoglobulin profiles before and after the intervention period. Result: Baseline assessments indicated comparable TCM syndrome scores and serum levels of interleukin-6 (IL-6), interleukin-17 (IL-17), interleukin-23 (IL-23), immunoglobulin A (IgA), immunoglobulin G (IgG), and immunoglobulin E (IgE) between groups (P>0.05). After treatment, the syndrome score of the study group was significantly lower than that of the control group, and the concentration of pro-inflammatory factors was also lower than that of the control group. The immune function of the study group was significantly improved, manifested as an increase in IgA and IgG levels compared with the control group, while IgE decreased. The difference was statistically significant (P<0.05). The total clinical effective rate of the study group was significantly higher than that of the control group, and the difference was statistically significant (P<0.05). Moreover, no drug-related serious adverse events occurred in either group. Conclusion: The adjunctive use of Yupingfeng granules with montelukast sodium significantly enhances therapeutic outcomes in pediatric allergic rhinitis. This synergistic approach effectively alleviates nasal symptoms (rhinorrhea, congestion) through concurrent suppression of inflammatory mediators and bidirectional immunomodulation, without increasing drug-related risks.

Objective: To observe the efficacy of Shenshuaining combined with compound alpha ketoacid tablets in the treatment of patients with chronic renal failure. Method: 82 patients with chronic renal failure admitted to Yongtai County Hospital from August 2022 to August 2024 were randomly divided into a control group and a test group using the envelope method. The control group was treated with oral compound alpha ketoacid tablets, while the test group was treated with Shenshuaining in addition. The clinical efficacy and drug side effects of two groups, as well as the renal function indicators, renal fibrosis indicators, and micro inflammation indicators before and after treatment were compared. The total effective rate of the experimental group (95.12%) was significantly higher than that of the control group (78.05%), and the difference was statistically significant (P<0.05). After 30 days of treatment, the levels of BUN, Scr, and Cys-C in both groups decreased significantly, with the experimental group showing a more significant decrease. The eGFR levels were significantly increased, with the experimental group showing a more significant increase, and the difference was statistically significant (P<0.05). After 30 days of treatment, the levels of TIMP-1, CTGF, FN, TNF-α, and IL-6 in both groups decreased significantly. The experimental group showed a more significant decrease, and the difference was statistically significant (P<0.05). There was no significant difference in the incidence of drug side effects between the experimental group (7.32%) and the control group (4.88%), and the difference was not statistically significant (P>0.05). Conclusion: The combination therapy of oral administration of Shenshuaining and compound alpha ketoacid tablets in patients with chronic renal failure has significant therapeutic effects, significantly improving renal function indicators, renal fibrosis indicators, and micro inflammatory indicators, with low drug side effects.

Lumbar disc herniation (LDH) is a common condition in clinical practice, particularly in orthopedics, often causing lower back and leg pain and affecting patients' quality of life. Traditional Chinese medicine acupuncture has been shown to be effective in treating LDH patients, offering advantages such as simplicity, convenience, affordability and reliability, and plays an irreplaceable role in treatment. The article reviews relevant literature on the mechanisms of action of acupuncture in the treatment of LDH over the past five years and summarizes the findings. The results indicate that acupuncture treatment for LDH is closely associated with multiple mechanisms of action, including reducing inflammation levels, improving bone metabolism, improving serum differential metabolite levels, regulating neurotransmitters, enhancing nerve conduction velocity, and improving blood rheology.

Objective: To investigate the effect of fenelidone for diabetic nephropathy combined with heart failure on patients. Method: 107 patients with diabetic nephropathy combined with chronic heart failure admitted to Putian Ninety-five Hospital from July 2022 to December 2024 were selected as the study subjects, and were randomly divided into 53 cases in the observation group and 54 cases in the control group using the lottery method. The control group was treated with metformin hydrochloride tablets with valsartan capsules, and the observation group was treated with combined fenetylline on the basis of the control group for 2 months. The efficacy, cardiac enzymes and urine microalbumin, and quality of life of the two groups were compared, and the incidence of adverse reactions was counted. Result: After treatment, the total effective rate of the observation group was higher than that of the control group, and the difference was statistically significant (P<0.05). After treatment, the indicators of cardiac enzymes and 24-h urinary microalbumin excretion rate decreased significantly in both groups, and compared with the control group, troponin I (cTnI), N-terminal B-type natriuretic peptide precursor (NT-proBNP), free fatty acid (FFA), and 24-h urinary microalbumin excretion rate in the observation group were lower, and the difference was statistically significant (P<0.05). The scores of all dimensions of quality of life in both groups increased after treatment compared with those before treatment, and compared with the control group, the observation group had higher scores in the physical domain, emotional domain, and other domains, and the difference was statistically significant (P<0.05). The difference in the incidence of adverse reactions between the two groups was not statistically significant (P>0.05). Conclusion: The adjuvant treatment of diabetic nephropathy combined with chronic heart failure can effectively improve the cardiac enzymes, urinary microalbumin excretion rate, and play a protective role in the recovery of cardiac and renal function, with good therapeutic effects and few adverse reactions, and high safety.

Objective: To explore the effect of warm palace plaster combined with traditional Chinese medicine characteristic nursing on pain, dysmenorrhea symptoms, and sleep quality in patients with dysmenorrhea. Method: According to the random number table method, 102 patients with dysmenorrhea who visited Songzi Traditional Chinese Medicine Hospital from May 2023 to May 2024 were divided into a warm uterine patch group (n=51) and a traditional Chinese medicine group (n=51). The warm palace patch group received warm palace patch intervention. The traditional Chinese medicine group added traditional Chinese medicine characteristic nursing (separated moxibustion and finger acupoint nursing intervention). After 6 treatment courses (1 menstrual cycle as 1 treatment course), the pain level, Traditional Chinese Medicine symptom score, dysmenorrhea symptoms, and sleep quality of the two groups were compared. Result: The VAS scores of the two groups before intervention were compared, and there was no significant difference (P>0.05). After 6 courses of intervention, the VAS scores of the third course and the sixth course of intervention in the two groups were lower than those before intervention, with statistically significant difference (P<0.05). The TCM symptom score of TCM group was lower than that of warm palace patch group, and the difference was statistically significant (P<0.05). The CMSS score of TCM group was lower than that of warm palace patch Group, and the difference was statistically significant (P<0.05). The PSQI of TCM group was lower than that of warm palace patch group, and the difference was statistically significant (P<0.05). Conclusion: Traditional Chinese medicine characteristic nursing combined with warm uterus patches can alleviate the pain of dysmenorrhea patients, and improve dysmenorrhea symptoms and sleep quality.

Objective: To investigate the efficacy of teprenone capsule combined with magnesium aluminum carbonate in the treatment of gastroduodenal ulcer and its effect on the healing of gastric mucosa. Method: 78 cases of gastroduodenal ulcer patients admitted to the First Hospital Affiliated to the School of Medicine of Zhejiang University from October 2022 to October 2024 were selected as the study subjects, and they were divided into the control group and the observation group according to the different medication regimens, with 39 cases in each group. The control group was treated with magnesium aluminum carbonate, and the observation group was treated with teprenone capsule combined with magnesium aluminum carbonate, and both groups continued treatment for 2 weeks. The clinical efficacy, symptom relief time, gastrointestinal hormone level changes and gastric mucosa healing were compared between the two groups. Result: After treatment, the total effective rate of treatment of the observation group was higher than that of the control group, and the difference was statistically significant (P<0.05). The time to relieve abdominal pain, abdominal distension, acid reflux, belching and other symptoms in the observation group was shorter than that in the control group, and the difference was statistically significant (P<0.05). Serum pepsinogen I (PG I), pepsinogen II (PG II) and gastrin-17 (G-17) levels were lower in the observation group than in the control group, and the difference was statistically significant (P<0.05). The gastric mucosa healing score of the observation group was lower than that of the control group, and the difference was statistically significant (P<0.05). Conclusion: Teprenone capsule combined with magnesium aluminum carbonate is effective in the treatment of gastroduodenal ulcer, which can shorten the time of symptomatic relief, improve the patient's gastrointestinal hormone level, and improve the quality of gastric mucosal healing.

Objective: To investigate the effect of Weisu Granules based on four joint program in the treatment of gastric mucosal lesions in patients with Helicobacter pylori (HP) infection complicated with atrophic gastritis. Method: A total of 90 patients with HP infection complicated with atrophic gastritis admitted to Wuxue Hospital of Traditional Chinese Medicine from April 2022 to April 2023 were selected as the research objects. They were divided into the Western medicine group, the traditional Chinese medicine group and the integrated traditional Chinese and Western medicine group according to the random number table method, with 30 cases in each group. The Western medicine group was treated with the quadruple therapy, the traditional Chinese medicine group was treated with Weisu Granules, and the integrated traditional Chinese and Western medicine group was treated with the quadruple therapy combined with Weisu Granules. The levels of gastrin (GAS), motilin (MTL), and gastrin-17 (G-17), as well as the TCM syndrome scores were compared among the three groups. Levels of inflammatory factors [C-reactive protein (CRP), interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α)]. Result: After treatment, the GAS and MTL in the integrated traditional Chinese and Western medicine group were lower than those in the Western medicine group and the traditional Chinese medicine group, while the G-17 level was higher than that in the Western medicine group and the traditional Chinese medicine group, and the differences were statistically significant (P<0.05). The TCM syndrome scores (belching, acid reflux, abdominal distension and abdominal pain) in the integrated Chinese and Western medicine group were lower than those in the Western medicine group and the traditional Chinese medicine group, and the difference was statistically significant (P<0.05). The levels of CRP, IL-6 and TNF-α in the integrated traditional Chinese and Western medicine group were lower than those in the Western medicine group and the traditional Chinese medicine group, and the difference was statistically significant (P<0.05). Conclusion: Gaisu Granules have a significant effect in the treatment of patients with HP infection complicated with atrophic gastritis. It can improve the clinical gastric discomfort symptoms of patients, effectively regulate the levels of gastrointestinal hormones, promote the repair of gastric mucosa, and reduce the inflammatory response.

Objective: To explore the clinical value of pearl eye drops combined with polyvinyl alcohol eye drops in the treatment of dry eye syndrome. Method: 112 patients with dry eye disease who were diagnosed and treated in Ezhou Aier Eye Hospital from December 2023 to October 2024 were randomly divided into two groups. The control group (56 cases and 112 eyes) were treated with polyvinyl alcohol eye drops, and the experimental group (56 cases and 112 eyes) were treated with pearl eye drops and polyvinyl alcohol eye drops. After 2 weeks of treatment, compared the overall efficacy, disease-related indicators, tear inflammatory factors and drug safety. Result: After treatment, comparisons between the experimental group and the control group showed that the total effective rate was higher in the experimental group, the Schirmer Tear Secretion Test (SIT) and the average tear film break-up time (BUT) were both longer in the experimental group, the Ocular Surface Disease Index (OSDI) was lower in the experimental group, the concentrations of interleukin-1 β (IL-1β), tumor necrosis factor -α (TNF-α), and interleukin-6 (IL-6) in the tear fluid were lower in the experimental group, with statistically significant difference (P<0.05). The difference in adverse reaction rates did not reach statistical significance (P>0.05). Conclusion: Pearl eye drops combined with polyvinyl alcohol eye drops in the treatment of dry eye syndrome can play positive synergistic effect. It is conducive to the improvement of the disease. And it can reduce the expression of inflammatory factors in tears, with good safety.

Objective: To investigate the effect of limaprost in the treatment of patients with lumbar spinal stenosis and influence for gait parameters. Method: 80 patients with lumbar spinal stenosis diagnosed and treated in 910th Hospital of the Joint Service Support Force of the Chinese People's Liberation Army from November 2023 to August 2024 were grouped by random number table. 40 cases of the control group were treated with routine treatment for lumbar spinal stenosis, and 40 cases of the observation group were treated with limaprost on the treatment of control group. Then the total effective rates for limaprost, lower back and leg pain situation [Visual Analogue Scale (VAS)], disease state [Chinese swiss spinal stenosis questionnaire (CSSS scale)] and gait parameters [routine gait indexes (step speed, step frequency and stride length) and gait symmetry indexes (stance phase and bipedal support phase)] of two groups before and after the treatment were compared. Result: The total effective rate for limaprost of observation group was significantly higher than that of control group. The lower back and leg VAS score, CSSS score and gait symmetry indexes of observation group 4 and 8 weeks after the treatment were significantly lower than those of control group. The routine gait indexes were all significantly higher than those of control group, and the differences were statistically significant (P<0.05). Conclusion: The effect of limaprost in the treatment of patients with lumbar spinal stenosis is better, and it can effectively control the lower backand leg pain, and improve the gait parameters. So its application value in the patients with lumbar spinal stenosis is higher.

Objective: To analyze the effect evaluation of acupuncture at Dong's unique acupoint on pain mediators and lumbar vertebral function in patients with lumbar disc herniation. Method: 97 patients with lumbar disc herniation admitted to the Acupuncture and Moxibustion Department of the Rehabilitation Hospital Affiliated to Fujian University of Chinese Medicine from March 2022 to February 2023 were selected as the study objects, and randomly divided into the control group (48 cases) and the study group (49 cases). The control group was given rehabilitation training combined with traditional Chinese medicine treatment, and the study group was given additional acupuncture treatment at Dong's unique acupoint. The therapeutic effect of the two groups was compared after 4 courses of treatment. Result: The lumbar function score of the study group was (22.07±1.98), which was significantly higher than that of the control group, and the difference was statistically significant (P<0.05). The scores of the main complaint pain scale and lumbar dysfunction index in the study group were (3.47±0.32) points and (22.81±2.05) points, which were significantly lower than those in the control group, with statistical significance (P<0.05). The levels of serotonin (468.72±43.08) ng/L and substance P (178.26±15.19) ng/mL in the study group were significantly lower than those in the control group, with statistical significance (P<0.05). The total effective rate of the control group was 77.08% (37/48) and that of the study group was 93.88% (46/49), which was significantly higher than that of the control group, and the difference was statistically significant (P<0.05). Conclusion: Acupuncture at Dong's uniqe acupoint is beneficial to relieve the pain degree of patients with lumbar disc herniation, improve the function of lumbar spine and treatment effect, and then reduce the expression of pain mediators, which has a good clinical treatment effect.

Objective: To investigate the clinical effect of Zopiclone and Alprazolam on elderly patients with insomnia in the community. Method: 70 elderly insomnia patients treated in the Chronic Disease Hospital of Shandong Province from September 2023 to September 2024 were selected for this study. The patients were randomly assigned into control group receiving Alprazolam, and an observation group receiving both Alprazolam and Zopiclone, with 35 each group. Clinical efficacy, sleep quality (PSQI), cognitive function (MMSE), treatment satisfaction, and adverse drug reactions between the two groups were compared. Result: After treatment, the observation group showed significant improvements in PSQI and MMSE scores compared to the control group. The clinical efficacy and treatment satisfaction were also significantly higher in the observation group, with statistically significant differences (P<0.05). There was no statistically significant difference in adverse drug reactions between the two groups (P>0.05). Conclusion:.The combination of Zopiclone and Alprazolam effectively improves sleep quality, cognitive function, and psychological status in elderly insomnia patients, and enhances treatment satisfaction.

Dexamethasone is a synthetic long-acting glucocorticoid, a fluorinated derivative of prednisolone, with anti-inflammatory, antitoxic, anti-immune and antishock effects, excitation of the central nervous system, affecting the hematopoietic system, promoting the secretion of gastric acid, inhibiting the pineal gland's secretion of melatonin, and decreasing iodine ion uptake by the thyroid gland, which has been widely used in clinical practice. For unexplained fever and osteoarthritic pain, it has the effect of temporarily reducing fever and alleviating pain, which is favored by clinicians, especially in the primary health care institutions is a large number of applications, and even reached the point of abuse. The article found that dexamethasone would have adverse reactions such as ergotism, hypokalemic paralysis, anaphylactic shock, mental abnormality, perineal itching, urinary incontinence, acanthosis nigricans, epilepsy, gastric perforation, and femoral head necrosis in clinical application, which would cause unnecessary pain to patients. These adverse reactions occurring in the clinical application of dexamethasone in recent years are now analyzed and summarized to provide reference for future clinical application.

Gout is a group of diseases caused by high blood uric acid deposition in the joints and tissues causing a variety of damage, with strong heterogeneity, severe cases can be complicated by cardiovascular and cerebrovascular diseases, renal failure, and ultimately may be life-threatening. In recent years, clinical trials have found that Chinese medicine has obvious advantages in the treatment of gouty arthritis, which can not only reduce clinical symptoms, but also reduce blood uric acid, and achieve the effect of treating both symptoms and root causes. This article collects the dialectical thoughts of ancient and modern doctors on gout, and then summarizes Simiao San, Xuanbi Decoction, White Tiger and Guizhi Decoction. The research progress of the four classic prescriptions of Guizhi Shaoyao Zhimu Decoction in the field of gout is expected to further clarify the dialectical logic of TCM treatment of gout and provide new ideas for clinical diagnosis and treatment.

Objective: To investigate the efficacy of combined administration of diquafosol sodium and cyclosporine in the treatment of dry eye disease. Method: A total of 110 patients with dry eye treated in our hospital from January 2022 to December 2023 were selected as cases and divided into two groups with 55 cases each by random number table method. The conventional group received cyclosporine eye drops, and the experimental group received desquafoxol sodium eye drops + cyclosporine eye drops. The treatment effect was compared. Result: After treatment, the effective rate, Schirmer test result and BUT value, disease symptom score and inflammatory factor level of the experimental group were better than those of the conventional group, with statistically significant difference (P<0.05). Conclusion: Diquafoxol sodium eye drops combined with cyclosporine eye drops have outstanding efficacy in the treatment of dry eye, which can effectively improve eye function and reduce disease symptoms, and reduce inflammation, and is worth promoting.

Objective: To explore the effectiveness of mind mapping health education in patients with colorectal cancer with temporary colostomy. Method: 130 patients with colorectal cancer with temporary enterostomy admitted to Jianyang First Hospital in Nanping City from June 2020 to June 2024 were selected the subjects, and were randomly into the study and the control group, 65 cases in group. The control received conventional rehabilitation nursing care, and the study group used thinking guide health education, and both groups received nursing care for a period of 12 weeks . Before and after the intervention, self-care ability, survival quality, peristoma skin status, awareness and complications were compared between the two groups. Result: After 12 weeks of intervention, erosion, discoloration, and tissue proliferation scores lower in study group compared the control, and difference was statisically sigifiant (P<0.05). The quality of cancer survival scores in the 3 domains of symptomatic domain, functional domain and general health status were elevated in study group compared the control group, the difference was statistcally signifcant (P<0.05). The scores the dimensions of self-care ability the study increased mpared with the trol group, and the diffence was statiscally signcant (P<0.05). Knowledge scores the 3 dimensions of complication recognition, stoma replacement, and precautions were elevated in the study compared with control group, difference was stastically signcant (P<0.05). The complicon rate of the study group was lwer than that of the control, and the difference was stastically signifnt (P<0.05). Conclusion: Mind mapping health education can better improve the quality of cancer survival and peristoma skin status of colorectal cancer patients with temporary colostomy, improve self-care ability and knowledge.

Objective: To analyze the role and value of transvaginal color Doppler ultrasound (transvaginal color Doppler ultrasound) in the clinical differential diagnosis of ectopic pregnancy rupture and ovarian corpus luteum rupture. Method: Patients with ruptured ectopic pregnancy and ruptured corpus luteum of the ovary admitted to Taishan Maternal and Child Health Hospital from May 2022 to May 2024 were selected as the research subjects, with 62 cases and 53 cases respectively. All patients underwent vaginal color Doppler ultrasound examination. The color Doppler ultrasound indicators, blood flow characteristics, diagnostic efficacy and consistency of pathological diagnosis of patients with different diseases were compared and calculated. Result: The ovarian volume, depth of the fluid dark area and diameter of the abnormal echo area in ruptured corpus luteum of the ovary were higher than those in ruptured ectopic pregnancy, and the difference was statistically significant (P<0.05). The comparison of blood flow signal patterns in patients with the two diseases showed statistically significant difference (P<0.05). In the images of ruptured ectopic pregnancy, point-like and strip-like blood flow signals were mainly found, while in the images of ruptured corpus luteum of the ovary, there were more circular blood flow signals. Among the efficacy indicators of vaginal color Doppler ultrasound in the differential diagnosis of the two lesions, the accuracy was 95.65%, the sensitivity was 94.34%, the specificity was 96.77%, the positive predictive value was 96.15%, and the negative predictive value was 95.24%, and it had extremely high consistency with the pathological diagnosis (Kappa=0.912, P<0.05). Conclusion: The application of vaginal ultrasound in clinical examination and differential diagnosis of ectopic pregnancy rupture and ovarian corpus luteum rupture is accurate and effective. It has good application results.

Objective: The effects of traditional Chinese medicine enema and external application of mirnitus on patients with acute pancreatitis were compared. Method: 60 patients with acute pancreatitis admitted to the Second People's Hospital Affiliated to Fujian University of Traditional Chinese Medicine from January 2023 to September 2024 were selected as the research objects. They were divided into the control group and the observation group by the random number table method, with 30 cases in each group. Both groups received routine care. The control group was given enema with traditional Chinese medicine, while the observation group was treated with external application of mirnitus. The syndrome of TCM, symptom recovery time and intra-abdominal pressure before and after the intervention in the two groups were compared. Result: Before the intervention, there was no statistically significant difference in the TCM syndrome scores between the two groups (P>0.05). After the intervention, the syndrome TCM of the patients all decreased, and the decrease in the observation group was higher than that in the control group, with statistically significant differences (P<0.05). The pain relief time, the disappearance time of abdominal distension and the cessation time of nausea and vomiting in the observation group were all shorter than those in the control group, and the differences were statistically significant (P<0.05). Before the intervention, there was no statistically significant difference in intra-abdominal pressure between the two groups (P>0.05). After 3 and 7 days of intervention, the intra-abdominal pressure of the patients gradually decreased, and the observation group was lower than the control group, and the difference was statistically significant (P<0.05). Conclusion: Enema with traditional Chinese medicine and external application of mirnitus can shorten the symptom recovery time of patients with acute pancreatitis, improve the TCM syndrome score and reduce intra-abdominal pressure.

Objective: To explore the application effect of percutaneous endoscopic lumbar disc herniation combined with radiofrequency ablation in lumbar intervertebral disc protrusion. Method: A total of 104 patients with lumbar intervertebral disc protrusion who visited Beijing DCN Orthopaedic Hospital from January 2021 to January 2024 were selected as the research subjects. They were divided into a control group of 52 cases and an observation group of 52 cases according to different treatment methods. The control group received percutaneous puncture low-temperature plasma radiofrequency ablation treatment, while the observation group received percutaneous endoscopic lumbar discectomy combined with radiofrequency ablation treatment. The therapeutic effects, functional recovery, pain relief and incidence of adverse reactions of the two groups were compared. The Japanese Orthopaedic Association (JOA) Assessment of Treatment score, Oswestry Disability Index Questionnaire (ODI) score, and Visual Analogue Scale (VAS) score were determined. Result: After treatment, the therapeutic effect of the observation group was better than that of the control group, the JOA score was higher than that of the control group, the ODI and VAS scores were lower than those of the control group, and the incidence and recurrence rates of adverse reactions were both lower than those of the control group. The differences were statistically significant (P<0.05). Conclusion: Percutaneous endoscopy combined with radiofrequency ablation can improve the therapeutic effect of lumbar intervertebral disc protrusion, promote pain relief and functional recovery, and reduce the incidence of adverse reactions.

Objective: To investigate the effectiveness of azithromycin in conjunction with Montelukast sodium for treating mycoplasma pneumoniae pneumonia in children. Method: A total of 100 pediatric patients diagnosed with mycoplasma pneumoniae pneumonia, who were treated in the hospital from May 2022 to March 2024 were chosen as study subjects. These patients were randomly divided into two groups, with 50 patients in each group. The control group received azithromycin alone, whereas the study group was given a combination of azithromycin and Montelukast sodium. The outcomes measured included treatment efficacy, lung function parameters [such as peak time ratio (t-PTEF/t-E), tidal volume (V-T), mid-inspiratory flow rate to mid-expiratory flow rate ratio (MTIF/MTEF), forced vital capacity (FVC), maximum peak expiratory flow rate (PEF), and forced expiratory volume in one second (FEV1)], inflammatory markers [C-reactive protein (CRP), procalcitonin (PCT), and erythrocyte sedimentation rate (ESR)], duration of symptom resolution (cough, wheezing, rales, and fever), and the occurrence of adverse effects (dizziness, nausea, vomiting, abdominal pain, and diarrhea) of two groups were compared. Result: The overall effectiveness in the study group was notably superior to that in the control group (P<0.05). After treatment, both groups showed improvements in lung function, but the study group exhibited better results (P<0.05). Both groups experienced a reduction in inflammatory marker levels compared to pre-treatment, but the study group had a more pronounced decrease (P<0.05). The study group also had a shorter symptom resolution time than the control group (P<0.05). Additionally, the incidence of adverse reactions was lower in the study group, with statistically significant difference (P<0.05). Conclusion: The combination of azithromycin and Montelukast sodium is effective in treating mycoplasma pneumonia in children, contributing to improving lung function, reducing inflammation, and accelarting clinical symptom improvement, with high therapeutic safety.

Objective: To study the efficacy of tirofiban in non-endovascular treatment of patients with wake ischemic stroke. Method: A total of 100 patients with wake ischemic stroke who received non-endovascular treatment in Xinyi People's Hospital from January 2023 to December 2024 were selected and divided into a control group and an experimental group, with 50 cases in each group, based on whether tirofiban was used for non-endovascular treatment after admission for wake ischemic stroke. The control group received conventional treatment, while the experimental group was treated with tirofiban in addition. The therapeutic effects and hematocrit, platelet count, platelet ratio, fibrinogen, NIHSS, mRS And ADL scores of the two groups were compared. Result: The effective rate of treatment in the experimental group was higher than that in the control group, and the difference was statistically significant (P<0.05). There was no statistically significant difference in hematocrit, platelet count, platelet ratio, fibrinogen level, NIHSS, mRS And ADL score between the two groups before treatment (P>0.05). After treatment, the hematocrit, platelet count, platelet ratio, fibrinogen level, NIHSS and mRS Score of both groups decreased, and those of the experimental group were lower than those of the control group. The ADL score of both groups increased, and that of the experimental group was higher than that of the control group (P<0.05). Conclusion: Tirofiban in the treatment of patients with ischemic stroke after awakening who received non-endovascular treatment is helpful to improve the rheological indicators of blood flow and neurological function of patients, and to enhance the mRS, ADL scores and therapeutic effects.

Objective: To elucidate the specific process and efficacy of acupoint application combined with ear-patch therapy in the treatment of COPD combined with cough. Method: From December 2023 to January 2025, 80 patients of COPD complicated with cough participated in this study from Nanning Traditional Chinese Medicine Hospital. According to the principle of randomization, patients were classified into control group and test group, with 40 cases in each group. The control group received general medication and nursing from the department, while the test group received acupuncture point application combined with ear-patch therapy. Compare the CCS scores , lung capacity, cough severity and cough related quality of life between two groups. Result: After applying acupoint patches combined with ear-patch therapy to treat cough, the test group showed clearly better on the CCS and VAS scales, lung capacity and cough related quality of life compared to the control group. Conclusion: The combination of acupoint application and plaster therapy effectively improves cough symptoms, lung capacity and cough related quality of life in COPD patients with cough.

Objective: To study the efficacy of Lactobacillus vaginal capsule combined with clotrimazole vaginal suppository in the treatment of mycotic vaginitis and the effect on vaginal environment. Method: 82 patients with mycotic vaginitis admitted to Shijingshan Teaching Hospital, Capital Medical University, Beijing Shijingshan Hospital from April 2023 to June 2024 were divided into two groups by random number table method, including control group (treated with clotrimazole vaginal suppository, 41 cases) and observation group (treated with lactobacillus vaginal capsule on the basis of observation group, 41 cases). The inflammation, vaginal environment, efficacy and adverse reactions were compared between the two groups. Result: Before treatment, no significant differences were observed in the levels of inflammatory mediators or the vaginal environment between the two groups (P>0.05). After treatment, the observation group exhibited a greater reduction in C-reactive protein (CRP), interleukin-6 (IL-6), tumor necrosis factor (TNF-α), vaginal secretion pH, and acetylglucosaminase compared to the control group (P<0.05). Additionally, the observation group experienced a more pronounced increase in vaginal hydrogen peroxide levels than the control group, with statistically significant difference (P<0.05). The treatment effectiveness rate was higher in the observation group than in the control group, with statistically significant difference (P<0.05). However, there were no significant differences between the two groups in the overall incidence of vulvar swelling, loss of appetite, and rash (P>0.05). Conclusion: The combination of Lactobacillus vaginal capsule and clotrimazole vaginal suppository in the treatment of mycotic vaginitis can alleviate the inflammatory response of patients, and improve and maintain the vaginal environment, with good efficacy, high safety.

Objective: To investigate the clinical efficacy of ipratropium bromide in patients with acute exacerbation of bronchial asthma (BA). Method: From January 2023 to June 2024, 100 patients with acute onset of BA admitted to the Second People's Hospital of Lanzhou were enrolled. The patients were divided into the control group (treated with budesonoid) and the observation group (treated with ipratropium bromide on this basis) by palpation. The symptom improvement time, clinical effect, air trapping index, pulmonary ventilation function and safety were compared between the two groups. Result: Compared with the control group, the improvement time of clinical symptoms in the observation group was shorter, the total effective rate of treatment, pH value, partial pressure of blood oxygen (PaO₂), the levels of FEV1, FEV1/FVC and PEF were higher, and the partial pressure of carbon dioxide (PaCO₂) was lower, and the　difference was statistically significant (P<0.05). There was no significant difference in the incidence of mild headache, abnormal liver function and abnormal gastrointestinal function between the two groups(P>0.05). Conclusion: The application of ipratropium bromide in the treatment of acute attack of BA can shorten the improvement time of clinical symptoms with good curative effect, and improves pulmonary ventilation function and air trapping index with good safety.

Objective: To study the effect of psychotherapy combined with sodium valproate treatment on the emotional stability of patients with bipolar disorder. Method: 102 patients with mania treated in Dongcheng District Mental Health Care Hospital of Beijing from June 2021 to June 2024 were selected as the study objects and divided into observation group and control group, with 51 patients in each group. The control group was treated with sodium valproate, and the observation group was supplemented with psychological treatment. The clinical efficacy, symptom score, emotional stability scale score, quality of life score and treatment satisfaction were evaluated. Result: The total effective rate of the observation group was higher than that of the control group, the difference was statistically significant (P<0.05). After treatment, the scores of the Baker-Lafansen Mania Scale (BRMS), Positive and Negative Symptom Scale (PANSS), self-rating Anxiety Scale (SAS) and self-rating Depression Scale (SDS) in the observation group were lower than those in the control group, with statistical significance (P<0.05). After treatment, the scores of the Exxon Emotional Stability Scale (EES) in the observation group were lower than those in the control group, and the difference was statistically significant (P<0.05). The score of GQOLI-74 in observation group was higher than that in control group, and the difference was statistically significant (P<0.05). The treatment satisfaction of the observation group was higher than that of the control group, the difference was statistically significant (P<0.05). Conclusion: Psychotherapy combined with sodium valproate has a good effect on patients with mania, which can improve the symptoms of mania, stabilize the mood of patients with mania, improve the quality of life and treatment satisfaction of patients.

Objective: To evaluate the clinical outcomes of modified Holmium Laser Enucleation of the Prostate (HoLEP) with maximum preservation of functional urethra. Method: A retrospective analysis was conducted on 216 patients with benign prostatic hyperplasia (BPH) treated in the hospital from January to December 2024, including 104 cases using modified HoLEP with functional urethral preservation (Group A) and 112 cases using traditional HoLEP (Group B). Assessment indicators included perioperative parameters, effectiveness indicators (IPSS score, QoL score, and PVR 1, 3, and 6 months postoperatively); and safety indicators [incidence of stress urinary incontinence （SUI） immediately after catheter removal and 1, 2, and 4 weeks after operation]. Result: All surgeries were successfully completed, and there were no significant differences in perioperative parameters between the two groups (P>0.05). Group A showed significantly better IPSS scores than Group B at 6 months postoperatively, and the difference was statistically significant (P<0.05). Regarding safety, Group A demonstrated significantly lower incidence of stress urinary incontinence both immediately after catheter removal and 1, 2, and 4 weeks postoperatively compared to Group B, and the differences were statistically significant (P<0.05). Conclusion: The modified HoLEP technique with maximum preservation of functional urethra maintains surgical efficacy while significantly reduces the incidence of postoperative urinary incontinence, demonstrating promising clinical value.

Objective: To investigate the effect of combined treatment of finerenone and dapagliflozin on patients with diabetic nephropathy (DN). Method: 100 DN patients treated in Beijing Shijingshan Hospital from February 2022 to February 2024 were taken as the subjects. All cases were assigned to control group (n=50 cases, treated with dapagliflozin) and observation group (n=50 cases, treated with dapagliflozin and finerenone) by random numerical table. The glucose metabolism indicators, inflammatory factors, renal function indicators, quality of life and adverse reactions in both groups were compared. Result: After 4 weeks of treatment, the observation group had lower glucose metabolism indicators, tumor necrosis factor - α (TNF - α), interleukin-1 β (IL-1 β), interleukin-6 (IL-6), high-sensitivity C-reactive protein (hs-CRP), serum creatinine (Scr), blood urea nitrogen (BUN), and 24-hour urinary protein quantity (24hUPE) levels compared to the control group. The estimated glomerular filtration rate (eGFR) level and 36-Item Short-Form Health Survey (SF-36) score in the observation group were higher compared with the control group (P<0.05). The comparison of the incidence of adverse reactions in both groups showed no statistically significant difference(P>0.05). Conclusion: The combination of finerenone and dapagliflozin has significant therapeutic effect in DN patients, which can effectively regulate glucose metabolism indicators, reduce inflammatory levels, improve renal function, and enhance the quality of life, with relatively high safety.

Objective: To explore the effect of metoprolol succinate sustained-release tablets in patients with coronary heart disease (CHD) after percutaneous coronary intervention (PCI). Method: A total of 201 CHD patients treated with PCI in Enshi Huiyi Rheumatology Hospital from February 2022 to February 2024 were selected and divided into two groups by random number table method, group B (n=100) received conventional drug treatment, and group A (n=101) was treated with metoprolol succinate extended-release tablets on the basis of group B. The clinical efficacy, cardiac function, hemodynamics, myocardial enzymes, and major adverse cardiovascular events in the two groups were observed. Result: The total effective rate of group A was higher than that of group B, and the difference was statistically significant (P<0.05). After 6 months of treatment, the left ventricular ejection fraction and 6-minute walk test in the two groups increased compared with the time of admission and were higher in group A than in group B, the left ventricular end-diastolic diameter and left ventricular end-systolic inner diameter in the two groups decreased compared with those at admission, and group A was lower than that in group B, the mean left atrial pressure, mean pulmonary artery pressure, and mean mitral valve pressure in the two groups decreased compared with the time of admission, and group A was lower than group B, the incidence of recurrent angina and heart failure in group A were significantly lower than those in group B，with statistically significant differences (P<0.05). There were no significant differences in the incidence of stent restenosis, stroke, and sudden cardiac death between the two groups (P>0.05).Conclusion: The application of metoprolol succinate sustained-release tablets in CHD patients undergoing PCI can improve hemodynamics and myocardial enzyme levels, promote the recovery of cardiac function, reduce the incidence of recurrent angina and heart failure, and improve clinical efficacy.

Objective: To explore the clinical effect of aerosol inhalation of salbutamol and budesonide micro pump for infantile asthma. Method: A total of 80 children with asthma in infants and young children treated in Longyan People's Hospital from January 2021 to January 2024 were selected as research objects and divided into control group and observation group by random number table method, with 40 cases in each group. The control group was treated with budesonide, and the observation group was treated with salbutamol. The clinical efficacy, resolution time, length of hospital stay, lung function, inflammatory factors and adverse reactions were compared between the two groups. Result: The total effective rate of observation group was higher than that of control group. The time of dyspnea, cough, wheezing and wheezing in the observation group were shorter than those in the control group. After treatment, the peak expiratory flow rate (PEF), forced expiratory volume in the first second (FEV1), forced vital capacity (FVC) and expiratory flow rate when forced to exhale 50% of vital capacity (FVE50%) in the observation group were higher than those in the control group. The levels of interleukin-1β (IL-1β) and interleukin-12 (IL-12) in observation group were lower than those in control group, and the differences were statistically significant (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion: In the clinical treatment of infant asthma, salbutamol and budesonide are effective, can improve the symptoms and lung function of children, reduce the level of inflammatory factors in the body, and are relatively safe.

Objective: To explore the application effect of graded nursing mode in emergency nursing of patients with acute pancreatitis and its impact on prognosis. Method: A total of 106 patients with acute pancreatitis admitted to the First Affiliated Hospital of Bengbu Medical College from June 2021 to June 2024 were selected. The patients were randomly divided into two groups with random number table: control group (n=52, receiving routine nursing intervention) and observation group (n=54, receiving graded nursing intervention). The emergency treatment time and clinical symptom relief time between two groups were recorded and compared. Before and after intervention, the psychological status of patients with Self Rating Anxiety Scale (SAS) and Self Rating Depression Scale (SDS) was evaluated, and the incidence of complications between the two groups was compared. Result: The waiting time, triage evaluation time, emergency observation time, and relief time of abdominal pain, fever, nausea, and vomiting in the observation group were all shorter than those in the control group (P<0.05). After intervention, both groups of patients showed a decreasing trend in SAS and SDS scores compared to before intervention (P<0.05). After intervention, the SAS and SDS scores of the observation group were lower than those of the control group at the same time (P<0.05). The incidence of complications in the observation group was lower than the control group (P<0.05). Conclusion: The hierarchical nursing model can effectively shorten the emergency treatment time of patients with acute pancreatitis, alleviate clinical symptoms, improve adverse psychological states, and reduce the incidence of complications.

Objective: To investigate the effects of ultrasound-guided dual nerve block technology on analgesia, motor function preservation, and postoperative recovery in ankle surgery patients. Method: A total of 80 patients undergoing ankle surgery at Xinhui District Hospital of Traditional Chinese Medicine in Jiangmen City, Guangdong Province from April to November 2024 were selected as subjects. The study was divided into experimental and control groups using equalized sequential matching. Equalized sequential matching was applied, with 40 cases in the control group receiving combined spinal-epidural anesthesia and 40 cases in the experimental group receiving ultrasound-guided popliteal popliteal nerve block combined with obturator block. The effectiveness of the control anesthesia protocol during surgical treatment was evaluated. Result: Analysis of heart rate, systolic blood pressure, diastolic blood pressure, and oxygen saturation levels showed no significant differences across time periods. Systolic and diastolic blood pressure remained unchanged before anesthesia initiation and at the end of surgery. However, the experimental group exhibited higher blood pressure at the start of surgery and 30 minutes post-surgery compared to the control group, with statistically significant difference (P<0.05). No significant difference was observed at 1 h postoperative, but statistically significant differences (P<0.05) were found at 12 h and 24 h postoperative, indicating better analgesia outcomes. The experimental group also demonstrated superior nerve block efficacy compared to the control group (P<0.05). Conclusion: During ankle surgery, implementing ultrasound-guided popliteal popliteal nerve block combined with obturator block ensures reliable anesthesia blockade, maintains stable circulatory status, and delivers high-quality analgesia.

Objective: To explore the application effect of arthroscopic total arthroscopic rotator cuff repair and arthroscopic-assisted small incision rotator cuff repair in the treatment of patients with rotator cuff injury and their influence on shoulder joint function. Method: A retrospective analysis was conducted on the clinical data of 80 patients with rotator cuff injury admitted to Beijing Huairou Hospital of Traditional Chinese Medicine from January 2021 to August 2024. They were divided into two groups according to the surgical methods. 40 patients in group A underwent arthroscopic total arthroscopic rotator cuff repair, and 40 patients in group B underwent arthroscopic-assisted small incision rotator cuff repair. The general information, operation time, intraoperative blood loss, postoperative hospital stay, and incidence of postoperative complications of the two groups were compared. As well as the Visual Analogue Scale (VAS) for pain before the operation, 3 months, 6 months, and 12 months after the operation, American Shoulder and Elbow Surgeons (ASES), the Shoulder Joint Function Score of the University of California, Los Angeles (UCLA), and shoulder joint function assessment indicators including shoulder joint range of motion, shoulder joint muscle strength classification, joint forward flexion, abduction, neutral position external rotation, muscle strength, etc. Result: There was no statistically significant difference between the two groups in terms of general information, postoperative hospital stay, incidence of postoperative complications, etc. (P>0.05). The operation time of group A was longer than that of group B, and the difference was statistically significant (P<0.05). The intraoperative blood loss was lower than that of group B, and the difference was statistically significant (P<0.05). The comparison of indicators such as VAS score, ASES score, UCLA score, shoulder joint range of motion, shoulder joint muscle strength grade, joint forward flexion, abduction, neutral position external rotation, and muscle strength between the two groups before the operation showed no statistically significant difference (P>0.05), but were significantly better than those before the operation at 3 months, 6 months, and 12 months after the operation. The difference was statistically significant (P<0.05), and group A was superior to group B at each time point, and the difference was statistically significant (P<0.05). Conclusion: Both arthroscopic total arthroscopic rotator cuff repair and small incision rotator cuff repair can effectively improve shoulder joint function, relieve pain and enhance the quality of life in the treatment of patients with rotator cuff injury. However, the former has a better therapeutic effect compared to the latter and is more suitable for the choice of patients with rotator cuff injury.

Objective: To investigate the effect of using pressure tourniquets throughout and halfway of total knee arthroplasty. Method: 120 patients with knee osteoarthritis (KOA) in the hospital from March 2022 to March 2024 were selected and randomly divided into two groups using a random number table: Group A and Group B, with 60 patients in each group. In total knee replacement surgery, Group A was given a full tourniquet, while Group B was given a half tourniquet. The intraoperative blood loss, surgical time, postoperative pain [Visual Analog Scale (VAS)], degree of swelling, quadriceps muscle strength [Manual Muscle Strength Test (MMT) score], and knee joint function [Hospital for Special Surgery Knee Score (HSS)] between two groups were compared. Result: The intraoperative blood output of patients in group B was higher than that in group A, and the operation time in group B was longer than that in group A (P<0.05). 1 d and 3 d after operation, VAS scores in group B were lower than those in group A (P<0.05). 1 d and 3 d after operation, the degree of limb swelling in group B was lower than that in group A (P<0.05). 7 d and 14 d after operation, the MMT scores of patients in group B were higher than those in the control group (P<0.05). 7 d and 14 d after operation, the HSS score in group B was higher than that in group A (P<0.05). Conclusion: The use of a half tourniquet in total knee arthroplasty can alleviate early postoperative pain and limb swelling in patients, promote the recovery of quadriceps muscle strength, and improve knee joint function. However, using a half tourniquet during surgery can prolong the patient's surgery time and increase intraoperative bleeding.

Objective: To explore the effects of aromatherapy combined with cognitive behavioral therapy on Chemotherapy-Induced Nausea and Vomiting (CINV), comfort level and quality of life in patients with colorectal cancer undergoing chemotherapy. Method: A total of 92 patients with colorectal cancer undergoing chemotherapy who visited Union Hospital Affiliated to Fujian Medical University from February 2023 to February 2024 were selected as the research subjects. They were divided into the observation group and the control group by the random number table method, with 46 cases in each group. The control group was intervened with aromatherapy, while the observation group was intervened with cognitive behavioral therapy on the basis of the control. The occurrence of nausea and vomiting (incidence of delayed nausea and vomiting, frequency of vomiting, and severity) in the two groups was recorded, and the Piper Fatigue Self-Assessment Scale-Revised (PFS-R), General Comfort Questionnaire (GCQ), and the Functional Living Index for Cancer (FLIC) before and after the intervention were compared between the two groups. Result: The incidence, frequency and severity of delayed nausea and vomiting in the observation group were all lower than those in the control group, and the difference was statistically significant (P<0.05). The PFS-R scores of both groups decreased after the intervention, and the behavioral, sensory, emotional and cognitive scores of the observation group were all lower than those of the control group, with statistically significant differences (P<0.05). The FLIC and GCQ of both groups increased after the intervention, and those of the observation group were higher than those of the control group, with statistically significant differences (P<0.05). Conclusion: For patients with colorectal cancer undergoing chemotherapy, the combination of aromatherapy and cognitive behavioral therapy can improve the symptoms of CINV, reduce cancer-related fatigue, enhance comfort, and improve the quality of life.

Meniscus injury is a common knee joint disease. As a common sports injury, it often leads to symptoms such as knee joint pain and limited movement, seriously affecting patients' daily life and athletic ability. This literature reviews the latest research progress in the treatment of meniscus injury with both traditional Chinese and Western medicine. The exploration of treatment methods has always been a hot topic in the field of orthopedics. In recent years, significant progress has been made in the clinical application of integrated traditional Chinese and Western medicine in the treatment of meniscus injuries. This article explores the advantages and clinical application prospects of different treatment methods, aiming to provide references for clinical treatment.

Objective: To explore the clinical efficacy and safety of different hysteroscopic surgical schemes for the treatment of endometrial polyps. Method: 100 patients with endometrial polyps admitted to Fujian Funeng Group General Hospital from January 2019 to January 2024 were selected, and they were divided into 49 cases of control group (treated with hysteroscopic resection) and 51 cases of observation group (treated with hysteroscopic cold knife resection) according to different treatment methods. The changes in preoperative and postoperative menstrual symptom scores, endometrial indicators, surgery related indicators, and incidence of complications were compared. Result: The operation time, blood loss and incidence of complications in the observation group were all lower than those in the control group, and the difference was statistically significant (P<0.05). 6 months after operation, the menstrual symptom scores, endometrial thickness, pulsatility index (PI), and resistance index (RI) of both groups showed a downward trend compared with those before the operation. Moreover, compared with the control group in the same period, the menstrual symptom scores, endometrial thickness, PI and RI of the observation group were lower, and the differences were statistically significant (P<0.05). There was no statistically significant difference in the hospital stay between the observation group and the control group (P>0.05). Conclusion: Both hysteroscopic resection and hysteroscopic cold knife resection have good polypectomy effects on endometrial polyps. It can reduce the risk of postoperative recurrence. However, compared with hysteroscopic resection, hysteroscopic cold knife resection has more advantages in improving surgical efficiency, improving patients' menstrual symptoms, and promoting endometrial recovery. It has better security.

Objective: To analyze the efficacy of ulinastatin combined with octreotide in patients with acute pancreatitis and its adverse reactions. Method: A retrospective analysis was conducted on the clinical data of 82 patients with acute pancreatitis admitted to First Hospital of Putian City from June 2022 to February 2024. All selected patients were divided into two groups with 41 cases in each group by treatment methods. The control group took octreotide alone, and the observation group added ustervastatin. The clinical efficacy, symptom disappearance and hospitalization time, white blood cell count (WBC), serum amylase (AMS), urinary amylase (UAMY) levels, serum inflammatory factors [interleukin-10 (IL-10), C-reactive protein (CRP), tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6)], and adverse reactions of two groups were compared. Result: After treatment, the clinical effect of observation group was higher than that of control group. The symptoms disappeared in the observation group and the hospitalization time was shorter than that in the control group. The levels of WBC, AMS, UAMY, CRP, IL-6 and TNF-α were lower than those of control group, and the levels of IL-10 were higher than those of control group, with statistically significant difference (P<0.05). The adverse reactions of the two groups were compared, with no statistically significant difference (P>0.05). Conclusion: The combination of ustepidem and octreotide can effectively improve the levels of detection factors: WBC in patients with acute pancreatitis, alleviate inflammation, shorten the duration of symptoms, and do not increase adverse reactions, which has higher safety.

Objective: To evaluate the efficacy of Chaihu Kegu Oyster Decoction in the treatment of esophageal reflux gastritis. Method: A total of 206 patients diagnosed with esophageal reflux gastritis admitted to the hospital from June 2022 to June 2024, were randomly assigned to two groups. The control group received rabeprazole sodium enteric-coated tablets, while the study group was administered Chaihu Kegu Oyster Decoction in addition to treatment regimen of the control group. Both groups underwent an 8-week treatment period. Traditional Chinese Medicine (TCM) syndrome scores, severity of reflux disease, and esophageal motor function were assessed and compared between the two groups. Result: 8 weeks after treatment, the study group exhibited significantly lower scores for acid reflux, retrosternal burning, upper abdominal discomfort, and noise compared to the control group (P<0.05). After 4 and 8 weeks treatment, RDQ scores in the study group were significantly lower than those in the control group (P<0.05). 8 weeks after treatment, the amplitude of esophageal constriction waves was higher, the transmission speed of esophageal peristaltic waves was faster, and the average duration of esophageal constriction was shorter in the study group compared to the control group (P<0.05). The therapeutic effect was superior in the study group (P<0.05), with lower rates of adverse reactions and recurrence (P<0.05). Conclusion: Chaihu Kegu Oyster Decoction effectively improves esophageal motor function; alleviates clinical symptoms, such as acid reflux and upper abdominal discomfort; reduces recurrence rates; and demonstrates safety.